Collated Gene Ontology terms

Biological process: GTPase activator activity(2013, 2016, 2017, 2020, 2021, 2024) guanyl-nucleotide exchange factor activity(2024) small GTPase binding(2006)

Molecular function: signal transduction2024 regulation of Rho protein signal transduction2006, 2024 regulation of small GTPase mediated signal transduction2024 defense response to virus2016 small GTPase mediated signal transduction2021 imaginal disc-derived leg morphogenesis2012 apical constriction involved in gastrulation2016 Rho protein signal transduction2013

Cellular component: membrane2024 cytosol2013 cytoplasm2021 apical part of cell2016

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
B7Z058_DROME
FlyBase»
3.9
RhoGAP71E Rho GTPase activating protein at 71E, isoform D Drosophila melanogaster
TI:7227 None
 
TAGAP_HUMAN
Ensembl»
2.3
TAGAP T-cell activation Rho GTPase-activating
protein (T-cell activation GTPase-activating protein)		 Homo sapiens
TI:9606 None
 
RHG20_HUMAN
Ensembl»
2.3
ARHGAP20 Rho GTPase-activating protein 20
(Rho-type GTPase-activating protein 20)		 Homo sapiens
TI:9606 None
 
RHG20_RAT
RGD»
2.3
Arhgap20 Rho GTPase-activating protein 20 (RA and RhoGAP
domain-containing protein) (RARhoGAP) (Rho-type GTPase-activating protein 20)		 Rattus norvegicus
TI:10116 None
 
D3ZXG5_RAT
RGD»
1.0
Tagap T-cell activation RhoGTPase activating protein Rattus norvegicus
TI:10116 None
 
TAGAP_MOUSE
Ensembl»
0.8
Tagap T-cell activation Rho GTPase-activating
protein (T-cell activation GTPase-activating protein)		 Mus musculus
TI:10090 None
 
A0A0G2K665_RAT
RGD»
0.5
Tgap1 GTPase activating protein testicular GAP1 Rattus norvegicus
TI:10116 None
   
A0A2I2ZPW0_GORGO
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Gorilla gorilla
TI:9593 None
 
A0A2I3RL56_PANTR
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Pan troglodytes
TI:9598 None
 
A0A3Q1M2Q1_BOVIN
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Bos taurus
TI:9913 None
   
A0A3Q2GW36_HORSE
Ensembl»
0.0
Rho-GAP domain-containing protein Equus caballus
TI:9796 None
   
A0A6I8N785_ORNAN
Ensembl»
0.0
LOC103167849 Rho-GAP domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8NB09_ORNAN
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7HP66_STRPU
EnsemblMetazoa»
0.0
Rho GTPase-activating protein 20 Strongylocentrotus purpuratus
TI:7668 None
   
A0A8M9PSX5_DANRE
ZFIN»
0.5
arhgap20 Rho GTPase-activating protein 20 Danio rerio
TI:7955 None
 
A0A9J7LP40_BRAFL
CTD»
0.0
LOC118422840 Uncharacterized protein LOC118422840 isoform X1 Branchiostoma floridae
TI:7739 None
   
A8XIE2_CAEBR
WormBase»
0.0
rga-2 Protein CBR-RGA-2 Caenorhabditis briggsae
TI:6238 None
 
C4LT51_ENTH1
EnsemblProtists»
0.0
EHI_148840 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
D3ZRJ5_RAT
RGD»
0.5
AABR07009260.1 Uncharacterized LOC100910852 Rattus norvegicus
TI:10116 None
   
D4AA19_RAT
RGD»
0.5
RGD1306519 Rho-GAP domain-containing protein Rattus norvegicus
TI:10116 None
   
F1Q8C7_DANRE
ZFIN»
0.5
zgc:77799 T cell activation RhoGTPase-activating protein a
(T-cell activation Rho GTPase-activating protein isoform X1)		 Danio rerio
TI:7955 None
 
F1S1S8_PIG
Ensembl»
0.0
Uncharacterized protein Sus scrofa
TI:9823 None
   
F1SB58_PIG
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Sus scrofa
TI:9823 None
   
F6ZP42_MACMU
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Macaca mulatta
TI:9544 None
   
F7F3K8_MONDO
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Monodelphis domestica
TI:13616 None
   
F7H213_MACMU
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Macaca mulatta
TI:9544 None
   
G1K9D8_ANOCA
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Anolis carolinensis
TI:28377 None
   
G1KCY3_ANOCA
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Anolis carolinensis
TI:28377 None
   
G3QPM6_GORGO
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Gorilla gorilla
TI:9593 None
 
H2M9K0_ORYLA
Ensembl»
0.0
LOC101155816 T-cell activation Rho GTPase-activating protein Oryzias latipes
TI:8090 None
   
H2MBS6_ORYLA
Ensembl»
0.0
LOC101155476 Rho GTPase-activating protein 20 Oryzias latipes
TI:8090 None
   
H2QTZ3_PANTR
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Pan troglodytes
TI:9598 None
 
I3LKJ5_PIG
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Sus scrofa
TI:9823 None
   
M3W3U9_FELCA
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Felis catus
TI:9685 None
 
M3WL65_FELCA
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Felis catus
TI:9685 None
 
M3X8G6_FELCA
Ensembl»
0.0
Rho-GAP domain-containing protein Felis catus
TI:9685 None
 
Q9XW53_CAEEL
WormBase»
0.5
rga-2 Rho GTPase-activating protein 20 Caenorhabditis elegans
TI:6239 None
 
W5MXS5_LEPOC
Ensembl»
0.0
Rho GTPase activating protein 20 Lepisosteus oculatus
TI:7918 None
 
W5NBM3_LEPOC
Ensembl»
0.0
Rho-GAP domain-containing protein Lepisosteus oculatus
TI:7918 None
 
W5NHV1_LEPOC
Ensembl»
0.0
T cell activation RhoGTPase activating protein Lepisosteus oculatus
TI:7918 None
 
A0A0G2K6E6_RAT
RGD»
0.0
LOC120093152 Similar to T-cell activation
Rho GTPase-activating protein isoform b		 Rattus norvegicus
TI:10116 None
   
A0A1L8G8K7_XENLA
Xenbase»
0.0
tagap.L T-cell activation Rho
GTPase-activating protein isoform X1		 Xenopus laevis
TI:8355 None
   
A0A1L8HB04_XENLA
Xenbase»
0.0
arhgap20.S Rho GTPase-activating protein 20 isoform X1 Xenopus laevis
TI:8355 None
   
A0A6I8QXZ0_XENTR
Xenbase»
0.0
arhgap20b Rho GTPase-activating protein 20 Xenopus tropicalis
TI:8364 None
   
A0A8I3MU89_CANLF
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Canis lupus
TI:9612 None
   
A0A8I3P9Q8_CANLF
Ensembl»
0.0
Rho-GAP domain-containing protein Canis lupus
TI:9612 None
   
A0A8I3PIB8_CANLF
Ensembl»
0.0
LOC119864445 Rho GTPase activating protein 20 Canis lupus
TI:9612 None
   
A0A8I3RRI3_CANLF
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Canis lupus
TI:9612 None
   
A0A8I5Y886_RAT
RGD»
0.0
LOC102550446 Rho GTPase-activating protein 20-like Rattus norvegicus
TI:10116 None
   
A0A8I5ZV48_RAT
RGD»
0.0
LOC120100815 Rho GTPase-activating protein 20-like Rattus norvegicus
TI:10116 None
   
A0A8I5ZY49_RAT
RGD»
0.0
LOC102555991 Uncharacterized LOC102555991 Rattus norvegicus
TI:10116 None
   
A0A8I6G5J2_RAT
RGD»
0.0
LOC365791 Rho GTPase-activating protein 20-like Rattus norvegicus
TI:10116 None
   
A0A8I6GKX2_RAT
RGD»
0.0
LOC678817 Similar to GTPase
activating protein testicular GAP1		 Rattus norvegicus
TI:10116 None
   
A0A8J0SP67_XENTR
Xenbase»
0.0
tagap T-cell activation Rho
GTPase-activating protein isoform X1		 Xenopus tropicalis
TI:8364 None
   
A0A8J0U486_XENLA
Xenbase»
0.0
arhgap20b.L Rho GTPase-activating protein 20 Xenopus laevis
TI:8355 None
   
A0A8J1MA96_XENLA
Xenbase»
0.0
arhgap20.L Rho GTPase-activating protein 20 isoform X1 Xenopus laevis
TI:8355 None
   
A0A8M1REZ7_DANRE
CTD»
0.0
arhgap20b Rho GTPase-activating protein 20 isoform X1 Danio rerio
TI:7955 None
   
A0A8M3AT33_DANRE
CTD»
0.0
tagapb T-cell activation Rho
GTPase-activating protein isoform X1		 Danio rerio
TI:7955 None
   
A0A8V0XGK1_CHICK
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Gallus gallus
TI:9031 None
   
A0A8V0XV08_CHICK
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Gallus gallus
TI:9031 None
   
A0A8V0YYS2_CHICK
Ensembl»
0.0
ARHGAP20B Rho-GAP domain-containing protein Gallus gallus
TI:9031 None
   
A0JM05_XENTR
Xenbase»
0.0
arhgap20 Rho GTPase activating protein 20 Xenopus tropicalis
TI:8364 None
 
A7SC20_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g209966 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
B3RYA2_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_56489 Rho-GAP domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B7PUH2_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW019271 Rho GTPase regulating protein, putative Ixodes scapularis
TI:6945 None
 
B9EHI3_MOUSE
Ensembl»
0.0
1700006A11Rik 1700006A11Rik protein (RIKEN
cDNA 1700006A11 gene)		 Mus musculus
TI:10090 None
 
C4LSL1_ENTH1
EnsemblProtists»
0.0
EHI_151700 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LV70_ENTH1
EnsemblProtists»
0.0
EHI_182930 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
F7CPC8_MONDO
Ensembl»
0.0
Rho-GAP domain-containing protein Monodelphis domestica
TI:13616 None
   
H9G7S8_ANOCA
Ensembl»
0.0
LOC103280657 Uncharacterized protein Anolis carolinensis
TI:28377 None
   
Q3V0P3_MOUSE
Ensembl»
0.0
Gm1527 Predicted gene 1527 Mus musculus
TI:10090 None
 
RHG20_MOUSE
Ensembl»
0.0
Arhgap20 Rho GTPase-activating protein 20 (RA and RhoGAP
domain-containing protein) (RARhoGAP) (Rho-type GTPase-activating protein 20)		 Mus musculus
TI:10090 None
 
A0A139WCU6_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_34190 Rho GTPase-activating protein 20-like Protein Tribolium castaneum
TI:7070 None
 
A0A1S4H6T4_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A9UXG0_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_24989 Rho-GAP domain-containing protein Monosiga brevicollis
TI:81824 None
 
B1N3W6_ENTH1
EnsemblProtists»
0.0
EHI_072080 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
B6ILK8_CAEBR
WormBase»
0.0
rga-9 Protein CBG25663 Caenorhabditis briggsae
TI:6238 None
 
C4LSA7_ENTH1
EnsemblProtists»
0.0
EHI_153150 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LT12_ENTH1
EnsemblProtists»
0.0
EHI_148420 Rho-GAP domain-containing protein Entamoeba histolytica
TI:5759 None
 
C4LTC3_ENTH1
EnsemblProtists»
0.0
EHI_045100 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LUF8_ENTH1
EnsemblProtists»
0.0
EHI_049570 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LVA5_ENTH1
EnsemblProtists»
0.0
EHI_182500 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LVB4_ENTH1
EnsemblProtists»
0.0
EHI_196960 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LWK5_ENTH1
EnsemblProtists»
0.0
EHI_069170 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LY00_ENTH1
EnsemblProtists»
0.0
EHI_035710 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LZS4_ENTH1
EnsemblProtists»
0.0
EHI_039030 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4M1X2_ENTH1
EnsemblProtists»
0.0
EHI_164790 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4M676_ENTH1
EnsemblProtists»
0.0
EHI_117610 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4M8N2_ENTH1
EnsemblProtists»
0.0
EHI_114370 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4MBC3_ENTH1
EnsemblProtists»
0.0
EHI_011070 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4MBR1_ENTH1
EnsemblProtists»
0.0
EHI_171170 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
D2A378_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_07566 Rho-GAP domain-containing protein Tribolium castaneum
TI:7070 None
 
D3Z8H5_RAT
RGD»
0.5
AABR07010333.1 Rho-GAP domain-containing protein Rattus norvegicus
TI:10116 None
   
E9FRQ4_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_219940 Rho-GAP domain-containing protein Daphnia pulex
TI:6669 None
 
E9PTA9_RAT
RGD»
0.0
LOC100910852 Uncharacterized LOC100910852 Rattus norvegicus
TI:10116 None
   
F1M6I1_RAT
RGD»
0.5
LOC691033 Similar to GTPase
activating protein testicular GAP1		 Rattus norvegicus
TI:10116 None
   
F1M6I2_RAT
RGD»
0.5
LOC499607 Similar to GTPase
activating protein testicular GAP1		 Rattus norvegicus
TI:10116 None
   
F7ALC2_HORSE
Ensembl»
0.0
Rho-GAP domain-containing protein Equus caballus
TI:9796 None
   
T1FGL9_HELRO
EnsemblMetazoa»
0.0
20207968 Rho-GAP domain-containing protein Helobdella robusta
TI:6412 None
 
U4PAK0_CAEEL
WormBase»
0.5
rga-9 Rho-GAP domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A0A2A6CIX6_PRIPA
EnsemblMetazoa»
0.0
WBGene00205449 Rga-2 Pristionchus pacificus
TI:54126 None
 
A0A6I8NZ97_ORNAN
Ensembl»
0.0
Rho-GAP domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A8I3NVD9_CANLF
Ensembl»
0.0
Rho-GAP domain-containing protein Canis lupus
TI:9612 None
   
A0A8I3P8K9_CANLF
Ensembl»
0.0
Rho-GAP domain-containing protein Canis lupus
TI:9612 None
   
A0A8I3PBG2_CANLF
Ensembl»
0.0
Rho-GAP domain-containing protein Canis lupus
TI:9612 None
   
A0A8R1UG62_PRIPA
EnsemblMetazoa»
0.0
WBGene00112295 Rho-GAP domain-containing protein Pristionchus pacificus
TI:54126 None
   
D3ZH11_RAT
RGD»
0.0
LOC103691539 Similar to GTPase
activating protein testicular GAP1		 Rattus norvegicus
TI:10116 None
   
E9G1S3_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_44312 Rho-GAP domain-containing protein Daphnia pulex
TI:6669 None
 
T1EJ76_HELRO
EnsemblMetazoa»
0.0
20196626 Rho-GAP domain-containing protein Helobdella robusta
TI:6412 None
 
T1FDF3_HELRO
EnsemblMetazoa»
0.0
20206852 Rho-GAP domain-containing protein Helobdella robusta
TI:6412 None
 
T1FGM0_HELRO
EnsemblMetazoa»
0.0
20207969 Rho-GAP domain-containing protein Helobdella robusta
TI:6412 None
 
A0A0G2K7I7_RAT
RGD»
0.0
AABR07010672.1 PH domain-containing protein Rattus norvegicus
TI:10116 None 		     
A0A5F8HFV5_MONDO
Ensembl»
0.0
T cell activation RhoGTPase activating protein Monodelphis domestica
TI:13616 None 		       
A0A8I5YCI0_RAT
RGD»
0.0
RGD1306704 Hypothetical LOC295483 Rattus norvegicus
TI:10116 None 		     
F7BJJ5_ORNAN
Ensembl»
0.0
T cell activation RhoGTPase activating protein Ornithorhynchus anatinus
TI:9258 None 		       
J3QPK7_MOUSE
Ensembl»
0.0
1700003H04Rik RIKEN cDNA 1700003H04 gene Mus musculus
TI:10090 None 		     
TGAP1_MOUSE
Ensembl»
0.0
Tagap1 T-cell activation GTPase-activating protein 1 Mus musculus
TI:10090 None