• Cluster UKP09843

• GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1

• Standard knownness: 2.9; Custom knownness: None; Num. species: 43; Orthology database: Panther19.0; Protein members: 49

Phylogenetic distribution

Chordates:	20/21
Echinoderms:	0/0
Hemichordates:	1/1
Annelids:	1/1
Molluscs:	0/0
Bryozoans:	0/0
Platyhelminthes:	0/0
Rotifers:	0/0
Nematodes:	3/3
Arthropods:	5/5
Tardigrades:	0/0
Placozoa:	0/1
Cnidaria:	0/1
Porifera:	0/0
Choanoflagellates+:	3/1
Dikarya:	0/14
Fungi (other):	0/1
Protozoa:	3/3
Excavates:	0/4
Harosa:	0/4
Hacrobia:	0/0
Plants:	0/39
Archea:	0/8
Bacteria:	7/35

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Proteins

UniProt ID Organism DB»	Standard knownness	clustom knownness	Gene name	Description	Species  [Show all]	GO terms	Seq. links	Protein domain links
MESH1_DROME FlyBase»	2.9		Mesh1	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (Metazoan SpoT homolog 1) (Mesh1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)	Drosophila melanogaster TI:7227 None	GO (7) F:IBA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity F:IEA - metal ion binding F:IEA - hydrolase activity F:IEA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity P:IDA - guanosine tetraphosphate catabolic process F:IDA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity P:IMP - response to starvation	EMBL (2) AE014297 BT024375		InterPro (2) IPR003607 - IPR006674 -
MESH1_DANRE ZFIN»	0.5		hddc3	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)	Danio rerio TI:7955 None	GO (4) F:IBA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity F:IEA - metal ion binding F:IEA - hydrolase activity F:IEA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	EMBL (1) BC092780		InterPro (2) IPR003607 - IPR006674 -
MESH1_HUMAN Ensembl»	0.5		HDDC3	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)	Homo sapiens TI:9606 None	GO (4) F:IBA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity F:IEA - metal ion binding F:IEA - hydrolase activity F:IEA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	EMBL (2) AC068831 BC033794		InterPro (2) IPR003607 - IPR006674 -
MESH1_MOUSE Ensembl»	0.0		Hddc3	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)	Mus musculus TI:10090 None	GO (3) F:IEA - metal ion binding F:IEA - hydrolase activity F:IEA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	EMBL (2) AK004078 BC038310		InterPro (2) IPR003607 - IPR006674 -
D4A500_RAT RGD»	0.5		Hddc3	HD domain containing 3	Rattus norvegicus TI:10116 None	GO (2) F:IBA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity F:IEA - metal ion binding			InterPro (2) IPR003607 - IPR006674 -
O18307_CAEEL WormBase»	0.5		CELE_ZK909.3 ZK909.3	HD domain-containing protein	Caenorhabditis elegans TI:6239 None	GO (1) F:IBA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	EMBL (1) BX284601		InterPro (2) IPR003607 - IPR006674 -
Q54KN3_DICDI dictyBase»	0.5		spoT	Guanosine-3',5'-bis 3'-diphosphatase	Dictyostelium discoideum TI:44689 None	GO (1) F:IBA - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	EMBL (1) AAFI02000099		InterPro (1) IPR003607 -
A0A8V0X4C9_CHICK Ensembl»	0.0		LOC107056801	HD domain containing 3	Gallus gallus TI:9031 None				InterPro (1) IPR003607 -