Collated Gene Ontology terms

Biological process: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity(2010, 2019, 2023) metal ion binding(2023) hydrolase activity(2023) transferase activity(2023) nucleic acid binding(2023) GTP diphosphokinase activity(2023)

Molecular function: response to starvation2010 guanosine tetraphosphate catabolic process2010

Cellular component:

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 3/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 7/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
H9GMV1_ANOCA
Ensembl»
0.0
HD domain-containing protein Anolis carolinensis
TI:28377 None
   
Q7Q7N0_ANOGA
EnsemblMetazoa»
0.0
1275936 AGAP004597-PA Anopheles gambiae
TI:7165 None
 
Q7QKR1_ANOGA
EnsemblMetazoa»
0.0
1269057 AGAP012646-PA Anopheles gambiae
TI:7165 None
   
F4P465_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_89127 HD domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F1MR07_BOVIN
Ensembl»
0.0
HDDC3 HD domain containing 3 Bos taurus
TI:9913 None
   
Q89UG1_BRADU
EnsemblBacteria»
0.0
blr1456 Blr1456 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
A0A9J7KW34_BRAFL
CTD»
0.0
LOC118412510 Guanosine-3',5'-bis(Diphosphate)
3'-pyrophosphohydrolase MESH1-like		 Branchiostoma floridae
TI:7739 None 		     
A8XW96_CAEBR
WormBase»
0.0
CBG19806 CBG_19806 Protein CBG19806 Caenorhabditis briggsae
TI:6238 None
 
O18307_CAEEL
WormBase»
0.5
CELE_ZK909.3 ZK909.3 HD domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A0A8I3MRZ7_CANLF
Ensembl»
0.0
HDDC3 HD domain containing 3 Canis lupus
TI:9612 None
   
A9WHG6_CHLAA
EnsemblBacteria»
0.0
Caur_3093 Metal-dependent phosphohydrolase HD sub domain Chloroflexus aurantiacus
TI:1108 None
   
F6QJB5_CIOIN
Ensembl»
0.0
HD domain-containing protein Ciona intestinalis
TI:7719 None
 
Q5KID5_CRYNJ
EnsemblFungi»
0.0
CND03360 HD/PDEase domain-containing protein Cryptococcus neoformans
TI:5207 None
 
MESH1_DANRE
ZFIN»
0.5
hddc3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein
3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)		 Danio rerio
TI:7955 None
 
E9H8N5_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_308647 HD domain-containing protein Daphnia pulex
TI:6669 None
 
F0ZTB3_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_155188 HD/PDEase domain-containing protein Dictyostelium purpureum
TI:5786 None
 
Q54KN3_DICDI
dictyBase»
0.5
spoT Guanosine-3',5'-bis 3'-diphosphatase Dictyostelium discoideum
TI:44689 None
 
MESH1_DROME
FlyBase»
2.9
Mesh1 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (Metazoan
SpoT homolog 1) (Mesh1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)		 Drosophila melanogaster
TI:7227 None
 
C4M411_ENTH1
EnsemblProtists»
0.0
EHI_195060 Metal-dependent phosphohydrolase, putative Entamoeba histolytica
TI:5759 None
 
M3W598_FELCA
Ensembl»
0.0
HDDC3 HD domain containing 3 Felis catus
TI:9685 None
 
A0A8V0X4C9_CHICK
Ensembl»
0.0
LOC107056801 HD domain containing 3 Gallus gallus
TI:9031 None 		     
Q7NIR7_GLOVI
EnsemblBacteria»
0.0
gll2115 Gll2115 protein Gloeobacter violaceus
TI:33072 None
 
A0A2I2YAG5_GORGO
Ensembl»
0.0
HDDC3 HD domain containing 3 Gorilla gorilla
TI:9593 None
 
T1EMJ6_HELRO
EnsemblMetazoa»
0.0
20197796 HD domain-containing protein Helobdella robusta
TI:6412 None
 
MESH1_HUMAN
Ensembl»
0.5
HDDC3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein
3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)		 Homo sapiens
TI:9606 None
 
B7Q0D7_IXOSC
EnsemblMetazoa»
0.0
8034036 Guanosine polyphosphate pyrophosphohydrolase/synthase, putative (EC
2.7.6.5) (Guanosine polyphosphate pyrophosphohydrolase/synthase, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
W5N9W8_LEPOC
Ensembl»
0.0
HD domain containing 3 Lepisosteus oculatus
TI:7918 None
 
Q8Y8T2_LISMO
EnsemblBacteria»
0.0
lmo0812 Lmo0812 protein Listeria monocytogenes
TI:1639 None
 
G7MVZ1_MACMU
Ensembl»
0.0
HDDC3 HD domain containing 3 Macaca mulatta
TI:9544 None
   
A9UYV8_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_25258 HD domain-containing protein Monosiga brevicollis
TI:81824 None
 
MESH1_MOUSE
Ensembl»
0.5
Hddc3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein
3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)		 Mus musculus
TI:10090 None
 
A0A6I8NEF5_ORNAN
Ensembl»
0.0
HDDC3 HD domain containing 3 Ornithorhynchus anatinus
TI:9258 None
   
A0A3B3IN91_ORYLA
Ensembl»
0.0
hddc3 HD domain containing 3 Oryzias latipes
TI:8090 None
   
K7BTU9_PANTR
Ensembl»
0.0
HDDC3 HD domain containing 3 Pan troglodytes
TI:9598 None
 
A0A2A6BM82_PRIPA
EnsemblMetazoa»
0.0
WBGene00103413 HD domain-containing protein Pristionchus pacificus
TI:54126 None 		 
 
A0A454XQT1_PRIPA
EnsemblMetazoa»
0.0
WBGene00094801 HD domain-containing protein Pristionchus pacificus
TI:54126 None 		 
 
A0A454XUZ0_PRIPA
EnsemblMetazoa»
0.0
WBGene00272635 HD domain-containing protein Pristionchus pacificus
TI:54126 None 		 
 
Q9I686_PSEAE
EnsemblBacteria»
0.0
PA0431 Bifunctional (P)ppGpp
synthetase/guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase		 Pseudomonas aeruginosa
TI:287 None
   
D4A500_RAT
RGD»
0.5
Hddc3 HD domain containing 3 Rattus norvegicus
TI:10116 None
   
A0A7M7RDN5_STRPU
EnsemblMetazoa»
0.0
HD domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
F1RMH8_PIG
Ensembl»
0.0
HDDC3 HD domain containing 3 Sus scrofa
TI:9823 None
   
P72810_SYNY3
EnsemblBacteria»
0.0
sll1660 Sll1660 protein Synechocystis sp.
TI:1148 None
 
Q6ZEC1_SYNY3
EnsemblBacteria»
0.0
sll7077 Sll7077 protein Synechocystis sp.
TI:1148 None
 
D6WD98_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_00063 Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase
MESH1-like Protein		 Tribolium castaneum
TI:7070 None
 
Q8PBN2_XANCP
EnsemblBacteria»
0.0
XCC1087 HD/PDEase domain-containing protein Xanthomonas campestris
TI:339 None
 
MESH1_XENTR
Xenbase»
0.0
hddc3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein
3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)		 Xenopus tropicalis
TI:8364 None