Collated Gene Ontology terms

Biological process: transmembrane transporter activity(2025) DNA binding(2019)

Molecular function: snRNA 3'-end processing2012, 2019, 2025 RNA polymerase II transcription initiation surveillance2025 snRNA processing2006, 2025 regulation of transcription elongation by RNA polymerase II2025 transmembrane transport2025 regulation of RNA splicing2009 positive regulation of neuron differentiation2019 positive regulation of gene expression2019 negative regulation of BMP signaling pathway2023

Cellular component: integrator complex2006, 2012, 2024, 2025 nucleus2017, 2024, 2025 cytoplasm2017, 2025 INTAC complex2025 nucleoplasm2015, 2024, 2025 cytosol2023, 2024, 2025 nuclear membrane2025 membrane2014, 2025

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
INT5_MOUSE
Ensembl»
3.0
Ints5 Integrator complex subunit 5 (Int5) Mus musculus
TI:10090 None
 
D3ZTW1_RAT
RGD»
2.0
Ints5 Integrator complex subunit 5 Rattus norvegicus
TI:10116 None
   
INT5_HUMAN
Ensembl»
4.1
INTS5 Integrator complex subunit 5 (Int5) Homo sapiens
TI:9606 None
 
INT5_DROME
FlyBase»
5.3
omd Integrator complex subunit 5
(Protein oocyte maintenance defects)		 Drosophila melanogaster
TI:7227 None
 
A0A5F7ZIG4_MACMU
Ensembl»
0.0
C14H11orf98 Integrator complex subunit 5 Macaca mulatta
TI:9544 None
   
A0A6I8NM36_ORNAN
Ensembl»
0.0
INTS5 Integrator complex subunit 5 Ornithorhynchus anatinus
TI:9258 None
   
A0A8I3MZK3_CANLF
Ensembl»
0.0
INTS5 Integrator complex subunit 5 Canis lupus
TI:9612 None
   
A0A8V0X0V3_CHICK
Ensembl»
0.5
INTS5 Integrator complex subunit 5 Gallus gallus
TI:9031 None
   
A1L552_BOVIN
Ensembl»
0.0
INTS5 Integrator complex subunit 5 (MGC143225 protein) Bos taurus
TI:9913 None
 
F6ZH90_MONDO
Ensembl»
0.0
INTS5 Integrator complex subunit 5 Monodelphis domestica
TI:13616 None
   
G3RUB0_GORGO
Ensembl»
0.0
INTS5 Integrator complex subunit 5 Gorilla gorilla
TI:9593 None
 
H2Q3W2_PANTR
Ensembl»
0.0
INTS5 Integrator complex subunit 5 Pan troglodytes
TI:9598 None
 
I3LMH3_PIG
Ensembl»
0.0
INTS5 Integrator complex subunit 5 Sus scrofa
TI:9823 None
   
INT5_DICDI
dictyBase»
1.0
DDB_G0279251 Integrator complex subunit 5-like protein Dictyostelium discoideum
TI:44689 None
 
A8XGP5_CAEBR
WormBase»
0.0
ints-5 Protein CBG12925 Caenorhabditis briggsae
TI:6238 None
 
A0A0R4IY96_DANRE
ZFIN»
1.3
ints5 Integrator complex subunit 5 Danio rerio
TI:7955 None
 
A0A1L8GCX3_XENLA
Xenbase»
0.0
ints5.S Integrator complex subunit 5-like Xenopus laevis
TI:8355 None
   
A0A1L8GJU2_XENLA
Xenbase»
0.0
ints5.L Integrator complex subunit 5 Xenopus laevis
TI:8355 None
   
A0A2A6CS17_PRIPA
EnsemblMetazoa»
0.0
WBGene00276189 Uncharacterized protein Pristionchus pacificus
TI:54126 None
   
A0A2R6WVT6_MARPO
euHCVdb»
0.0
MARPO_0054s0071 Uncharacterized protein Marchantia polymorpha
TI:3197 None
 
A0A7I4BIE9_PHYPA
EnsemblPlants»
0.0
LOC112272779 Uncharacterized protein Physcomitrium patens
TI:3218 None
 
A0A7M7PMY0_STRPU
EnsemblMetazoa»
0.0
Integrator complex subunit 5 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7PR69_STRPU
EnsemblMetazoa»
0.0
Integrator complex subunit 5 Strongylocentrotus purpuratus
TI:7668 None
   
A0A9J7N040_BRAFL
euHCVdb»
0.0
LOC118421764 Integrator complex subunit 5-like Branchiostoma floridae
TI:7739 None
   
B3RK36_TRIAD
CTD»
0.0
TRIADDRAFT_51610 Integrator complex subunit
5 C-terminal domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
D6X1X5_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_12371 Uncharacterized protein Tribolium castaneum
TI:7070 None
 
F0Z891_DICPU
TubercuList»
0.0
DICPUDRAFT_96433 Integrator complex subunit
5 C-terminal domain-containing protein		 Dictyostelium purpureum
TI:5786 None
 
F6V4C4_XENTR
Xenbase»
0.0
ints5 Glucosidase, alpha; neutral AB
(Integrator complex subunit 5)		 Xenopus tropicalis
TI:8364 None
   
H2LBN7_ORYLA
Ensembl»
0.0
INTS5 Integrator complex subunit 5 Oryzias latipes
TI:8090 None
   
H3H0M1_PHYRM
EnsemblProtists»
0.0
Uncharacterized protein Phytophthora ramorum
TI:164328 None
 
H9GM71_ANOCA
Ensembl»
0.0
Integrator complex subunit 5 Anolis carolinensis
TI:28377 None
   
Q7QBI6_ANOGA
EnsemblMetazoa»
0.0
AgaP_AGAP003159 AGAP003159-PA Anopheles gambiae
TI:7165 None
 
Q9U267_CAEEL
WormBase»
0.5
ints-5 Integrator complex subunit 5 Caenorhabditis elegans
TI:6239 None
 
T1FHD3_HELRO
EnsemblMetazoa»
0.0
20208232 Uncharacterized protein Helobdella robusta
TI:6412 None
 
A0A2R6WVT2_MARPO
neXtProt»
0.0
MARPO_0054s0074 Uncharacterized protein Marchantia polymorpha
TI:3197 None
 
A0ABI8ARZ5_FELCA
Ensembl»
0.0
INTS5 Integrator complex subunit 5 Felis catus
TI:9685 None
   
A7T0L3_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g220484 Integrator complex subunit
5 N-terminal domain-containing protein		 Nematostella vectensis
TI:45351 None
 
A8WLR7_CAEBR
WormBase»
0.0
CBG24917 CBG_24917 Protein CBG24917 Caenorhabditis briggsae
TI:6238 None
 
E9H8Q5_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_216438 Integrator complex subunit
5 C-terminal domain-containing protein		 Daphnia pulex
TI:6669 None
 
F7BN02_CIOIN
Ensembl»
0.0
Integrator complex subunit
5 C-terminal domain-containing protein		 Ciona intestinalis
TI:7719 None
 
H2XZK3_CIOIN
Ensembl»
0.0
Integrator complex subunit
5 N-terminal domain-containing protein		 Ciona intestinalis
TI:7719 None