Collated Gene Ontology terms

Biological process: zinc ion binding(2025) protein-folding chaperone binding(2013) metal ion binding(2025) molecular adaptor activity(2018) Hsp90 protein binding(2015, 2023) clathrin binding(2024) Hsp70 protein binding(2015)

Molecular function: protein folding2013 protein stabilization2024, 2025 post-translational protein targeting to endoplasmic reticulum membrane2018 box C/D snoRNP assembly2013, 2024 regulation of locomotor rhythm2015 protein-containing complex assembly2024 post-transcriptional regulation of gene expression2016 negative regulation of motor neuron apoptotic process2015 meiotic cell cycle2025 clathrin-dependent endocytosis2024
clathrin coat disassembly2023

Cellular component: R2TP complex2013, 2016, 2025 cytosol2009, 2024, 2025 cytoplasm2015, 2018, 2024, 2025 nucleus2009, 2018, 2025 protein folding chaperone complex2025 mitochondrion2014, 2018, 2025 membrane2020 TRC complex2018 RPAP3/R2TP/prefoldin-like complex2025 vesicle2024
phagocytic vesicle2006 mitotic spindle pole body2009 cilium2025 ciliary tip2025 ciliary basal body2025 cell division site2009 acrosomal vesicle2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 3/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 8/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 4/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A1Y1HNQ3_KLENI
euHCVdb»
0.0
KFL_000350180 RNA polymerase II-associated protein 3 Klebsormidium nitens
TI:105231 None 		 
 
A0A287B0E7_PIG
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Sus scrofa
TI:9823 None
 
A0A2K3D721_CHLRE
euHCVdb»
0.0
CHLRE_12g544752v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
A0A6I8MZ96_ORNAN
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Ornithorhynchus anatinus
TI:9258 None
   
A0A7I4FTJ9_PHYPA
EnsemblPlants»
0.0
RNA polymerase II-associated protein 3 Physcomitrium patens
TI:3218 None 		 
 
A0A7M7MZU6_STRPU
EnsemblMetazoa»
0.0
RNA polymerase II-associated protein 3 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A8I3Q0F2_CANLF
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Canis lupus
TI:9612 None
   
A0A8V0YMJ4_CHICK
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Gallus gallus
TI:9031 None
   
A0A9J7L5H9_BRAFL
neXtProt»
0.0
LOC118415639 RNA polymerase II-associated protein 3 Branchiostoma floridae
TI:7739 None 		     
A0A9J7M5Z3_BRAFL
neXtProt»
0.0
LOC118429115 Uncharacterized protein LOC118429115 Branchiostoma floridae
TI:7739 None
   
A0ABI8AE42_FELCA
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Felis catus
TI:9685 None 		     
A0BW60_PARTE
neXtProt»
0.0
GSPATT00032629001 RNA-polymerase II-associated protein
3-like C-terminal domain-containing protein		 Paramecium tetraurelia
TI:5888 None
 
A0CSP1_PARTE
euHCVdb»
0.0
GSPATT00010080001 Uncharacterized protein Paramecium tetraurelia
TI:5888 None 		 
 
A2FES2_TRIV3
TubercuList»
0.0
TVAG_140980 RNA polymerase II-associated protein 3 Trichomonas vaginalis
TI:5722 None
 
A7SN44_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g27358 RNA polymerase II-associated protein 3 Nematostella vectensis
TI:45351 None 		 
 
A7T0P8_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g220540 RNA-polymerase II-associated protein
3-like C-terminal domain-containing protein		 Nematostella vectensis
TI:45351 None 		 
 
A7T0P9_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g176010 RNA polymerase II-associated protein 3 Nematostella vectensis
TI:45351 None 		 
 
A8BSN2_GIAIC
TubercuList»
0.0
GL50803_0021498 Serine/threonine protein phosphatase 5 Giardia intestinalis
TI:5741 None 		 
 
A9UV33_MONBE
euHCVdb»
0.0
MONBRDRAFT_36345 RNA polymerase II-associated protein 3 Monosiga brevicollis
TI:81824 None 		 
 
B6IKP2_CAEBR
WormBase»
0.0
rpap-3 RNA polymerase II-associated protein 3 Caenorhabditis briggsae
TI:6238 None 		 
 
B7PI94_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW017856 RNA polymerase II-associated protein 3 Ixodes scapularis
TI:6945 None 		 
 
B8C217_THAPS
neXtProt»
0.0
THAPSDRAFT_5128 Uncharacterized protein Thalassiosira pseudonana
TI:35128 None 		 
 
C4LXR3_ENTH1
TubercuList»
0.0
EHI_014270 RNA polymerase II-associated protein 3 Entamoeba histolytica
TI:5759 None 		 
 
D6WQY6_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_09385 RNA polymerase II-associated protein 3 Tribolium castaneum
TI:7070 None 		 
 
D8QSW3_SELML
euHCVdb»
0.0
SELMODRAFT_7420 Uncharacterized protein Selaginella moellendorffii
TI:88036 None 		 
 
D8R238_SELML
euHCVdb»
0.0
SELMODRAFT_406354 RNA polymerase II-associated protein 3 Selaginella moellendorffii
TI:88036 None 		 
 
D8S3B5_SELML
euHCVdb»
0.0
SELMODRAFT_107379 Uncharacterized protein Selaginella moellendorffii
TI:88036 None 		 
 
D8S5L3_SELML
euHCVdb»
0.0
SELMODRAFT_109473 Uncharacterized protein Selaginella moellendorffii
TI:88036 None 		 
 
D8S7X3_SELML
euHCVdb»
0.0
SELMODRAFT_110865 Uncharacterized protein Selaginella moellendorffii
TI:88036 None 		 
 
D8SMN3_SELML
neXtProt»
0.0
SELMODRAFT_7530 Uncharacterized protein Selaginella moellendorffii
TI:88036 None 		 
 
E3K9L4_PUCGT
TubercuList»
0.0
PGTG_07362 RNA polymerase II-associated protein 3 Puccinia graminis
TI:5297 None 		 
 
E9ACV9_LEIMA
TubercuList»
0.0
LMJF_27_2390 RNA polymerase II-associated protein 3 Leishmania major
TI:5664 None 		 
 
F1A349_DICPU
TubercuList»
0.0
DICPUDRAFT_159046 RING-type domain-containing protein Dictyostelium purpureum
TI:5786 None
 
F1N0V7_BOVIN
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Bos taurus
TI:9913 None 		     
F1R498_DANRE
ZFIN»
0.0
rpap3 RNA polymerase II-associated protein 3 Danio rerio
TI:7955 None 		 
 
F4P4X7_BATDJ
euHCVdb»
0.0
BATDEDRAFT_33331 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None 		 
 
F4PCS8_BATDJ
euHCVdb»
0.0
BATDEDRAFT_36163 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None 		 
 
F7DHF7_HORSE
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Equus caballus
TI:9796 None
   
F7H693_MACMU
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Macaca mulatta
TI:9544 None
   
G1K9S5_ANOCA
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Anolis carolinensis
TI:28377 None
   
G3SI46_GORGO
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Gorilla gorilla
TI:9593 None
 
H2LZ12_ORYLA
Ensembl»
0.0
rpap3 RNA polymerase II-associated protein 3 Oryzias latipes
TI:8090 None 		     
H3GBC7_PHYRM
EnsemblProtists»
0.0
Uncharacterized protein Phytophthora ramorum
TI:164328 None 		 
 
H3GE50_PHYRM
EnsemblProtists»
0.0
RNA polymerase II-associated protein 3 Phytophthora ramorum
TI:164328 None 		 
 
H9H6B7_MONDO
Ensembl»
0.0
RNA polymerase II-associated protein 3 Monodelphis domestica
TI:13616 None 		     
K7BF62_PANTR
Ensembl»
0.0
RPAP3 RNA polymerase II-associated protein 3 Pan troglodytes
TI:9598 None
 
MUG93_SCHPO
PomBase»
0.9
mug93 Meiotically up-regulated gene 93 protein Schizosaccharomyces pombe
TI:4896 None
 
Q18405_CAEEL
WormBase»
0.0
rpap-3 RNA polymerase II-associated protein 3 Caenorhabditis elegans
TI:6239 None 		 
 
Q381E8_TRYB2
TubercuList»
0.0
Tb11.01.8070 Uncharacterized protein Trypanosoma brucei
TI:5691 None
 
Q4Q4P2_LEIMA
TubercuList»
0.0
LMJF_32_3800 Uncharacterized protein Leishmania major
TI:5664 None 		 
 
Q54RV7_DICDI
dictyBase»
0.0
DDB_G0282885 RNA polymerase II-associated protein 3 Dictyostelium discoideum
TI:44689 None 		 
 
Q55DL5_DICDI
dictyBase»
0.5
DDB_G0269614 RING zinc finger-containing protein Dictyostelium discoideum
TI:44689 None
 
Q585V5_TRYB2
TubercuList»
0.0
30J2.25 RNA polymerase II-associated protein 3 Trypanosoma brucei
TI:5691 None
 
Q59SJ2_CANAL
CGD»
0.0
SEC72 Sec63 complex subunit Candida albicans
TI:5476 None 		 
 
Q5A857_CANAL
CGD»
0.0
CAALFM_CR00830WA orf19.10782 RNA polymerase II-associated protein 3 Candida albicans
TI:5476 None 		 
 
Q5KP57_CRYD1
TubercuList»
0.0
CNA04110 ER organization and
biogenesis-related protein, putative		 Cryptococcus deneoformans
TI:40410 None
 
Q75EM5_EREGS
euHCVdb»
0.0
AGOS_AAR054C AAR054Cp Eremothecium gossypii
TI:33169 None 		 
 
Q9V3E9_DROME
FlyBase»
2.6
spag RNA polymerase II-associated protein 3 Drosophila melanogaster
TI:7227 None
 
RPAP3_CHICK
CTD»
0.0
RPAP3 RNA polymerase II-associated protein 3 Gallus gallus
TI:9031 None 		 
 
RPAP3_HUMAN
Ensembl»
0.6
RPAP3 RNA polymerase II-associated protein 3 Homo sapiens
TI:9606 None
 
RPAP3_MOUSE
Ensembl»
0.0
Rpap3 RNA polymerase II-associated protein 3 Mus musculus
TI:10090 None
 
RPAP3_RAT
RGD»
0.0
Rpap3 RNA polymerase II-associated protein 3 Rattus norvegicus
TI:10116 None
 
RPAP3_XENLA
Xenbase»
0.0
rpap3 RNA polymerase II-associated protein 3 Xenopus laevis
TI:8355 None
 
RPAP3_XENTR
Xenbase»
0.0
rpap3 RNA polymerase II-associated protein 3 Xenopus tropicalis
TI:8364 None 		 
 
TAH1_YEAST
SGD»
7.0
TAH1 TPR repeat-containing protein
associated with Hsp90		 Saccharomyces cerevisiae
TI:4932 None
 
W5NIG9_LEPOC
Ensembl»
0.0
RNA polymerase II-associated protein 3 Lepisosteus oculatus
TI:7918 None