Collated Gene Ontology terms

Biological process: hydrolase activity(2023) phosphoric diester hydrolase activity(2019, 2021, 2023) manganese ion binding(2019, 2023) GMP binding(2019, 2023) AMP binding(2019, 2023) nucleotide binding(2023) metal ion binding(2023) rhamnogalacturonan endolyase activity(2023) lyase activity(2023) catalytic activity(2023)
carbohydrate binding2023

Molecular function: polysaccharide catabolic process2023 podocyte development2014 organic substance catabolic process2023 cell wall organization2023 cell wall modification2017 carbohydrate metabolic process2023

Cellular component: membrane2023 extracellular region2023

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 7/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 1/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 5/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
MPPD1_HUMAN
Ensembl»
0.0
MPPED1 Metallophosphoesterase domain-containing protein 1 (EC
3.1.-.-) (Adult brain protein 239) (239AB)		 Homo sapiens
TI:9606 None
 
A0A2I2YM18_GORGO
Ensembl»
0.0
MPPED1 Metallophosphoesterase domain containing 1 Gorilla gorilla
TI:9593 None
 
MPPD2_HUMAN
Ensembl»
2.0
MPPED2 Metallophosphoesterase MPPED2 (EC 3.1.-.-) (Fetal brain
protein 239) (239FB) (Metallophosphoesterase domain-containing protein 2)		 Homo sapiens
TI:9606 None
 
MPPD1_MOUSE
Ensembl»
0.0
Mpped1 Metallophosphoesterase domain-containing protein
1 (EC 3.1.-.-)		 Mus musculus
TI:10090 None
 
MPPD2_RAT
RGD»
3.2
Mpped2 Metallophosphoesterase MPPED2 (EC 3.1.-.-) (239FB) (Fetal brain
protein 239 homolog) (Metallophosphoesterase domain-containing protein 2)		 Rattus norvegicus
TI:10116 None
 
Q7ZUB6_DANRE
ZFIN»
0.8
brpl Fetal brain protein 239 (Metallophosphoesterase domain containing 2) (Metallophosphoesterase
domain containing 2b isoform X1) (Metallophosphoesterase domain-containing 2b) (Mpped2 protein)		 Danio rerio
TI:7955 None
 
G3R4B9_GORGO
Ensembl»
0.0
MPPED2 Metallophosphoesterase domain containing 2 Gorilla gorilla
TI:9593 None
 
W5ND41_LEPOC
Ensembl»
0.0
Metallophosphoesterase domain containing 1 Lepisosteus oculatus
TI:7918 None
 
F6WJ08_MACMU
Ensembl»
0.0
MPPED2 Metallophosphoesterase MPPED2 isoform 1
(Metallophosphoesterase domain containing 2)		 Macaca mulatta
TI:9544 None
 
YW12_CAEEL
WormBase»
0.0
T07D4.2 UPF0046 protein T07D4.2 Caenorhabditis elegans
TI:6239 None
 
A0A2I3S9A3_PANTR
Ensembl»
0.0
MPPED2 Metallophosphoesterase domain containing 2 Pan troglodytes
TI:9598 None
 
B7PAE2_IXOSC
EnsemblMetazoa»
0.0
8026945 Metallophosphoesterase domain-containing
protein, putative		 Ixodes scapularis
TI:6945 None
 
RGLC_EMENI
EnsemblFungi»
0.0
rglC Probable rhamnogalacturonate lyase
C (EC 4.2.2.23)		 Emericella nidulans
TI:162425 None
 
T1F0M8_HELRO
EnsemblMetazoa»
0.0
20202378 Calcineurin-like phosphoesterase
domain-containing protein		 Helobdella robusta
TI:6412 None
 
A0A0D1DZF5_USTMA
EnsemblFungi»
0.0
UMAG_11726 Calcineurin-like phosphoesterase
domain-containing protein		 Ustilago maydis
TI:5270 None
 
A0A139WKX5_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_32520 Metallophosphoesterase domain-containing
protein 1-like Protein		 Tribolium castaneum
TI:7070 None
 
A0A1Y1I6S0_KLENI
EnsemblPlants»
0.0
KFL_002760100 Calcineurin-like phosphoesterase
domain-containing protein		 Klebsormidium nitens
TI:105231 None 		 
 
A0A2A6B8M8_PRIPA
EnsemblMetazoa»
0.0
WBGene00112166 Calcineurin-like phosphoesterase
(Major sperm protein)		 Pristionchus pacificus
TI:54126 None
 
A0A2A6BRJ8_PRIPA
EnsemblMetazoa»
0.0
WBGene00280235 Calcineurin-like phosphoesterase Pristionchus pacificus
TI:54126 None
 
A0A2A6CPG4_PRIPA
EnsemblMetazoa»
0.0
WBGene00112826 Calcineurin-like phosphoesterase Pristionchus pacificus
TI:54126 None
 
A0A2I2U676_FELCA
Ensembl»
0.0
MPPED1 Metallophosphoesterase domain containing 1 Felis catus
TI:9685 None 		 
 
A0A2I3RPJ3_PANTR
Ensembl»
0.0
MPPED1 Pan troglodytes
TI:9598 None 		 
 
A0A2K3D4E5_CHLRE
EnsemblPlants»
0.0
CHLRE_12g525550v5 Calcineurin-like phosphoesterase
domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None
 
A0A454XWP6_PRIPA
EnsemblMetazoa»
0.0
WBGene00091225 Calcineurin-like phosphoesterase Pristionchus pacificus
TI:54126 None
 
A0A803KJK0_XENTR
Xenbase»
0.0
mpped2 Metallophosphoesterase MPPED2 (Metallophosphoesterase MPPED2 isoform X1) (Metallophosphoesterase domain-containing
2) (Novel calcineurin-like phosphoesterase (Ortholog of human c11orf8))		 Xenopus tropicalis
TI:8364 None
 
A0CCW2_PARTE
EnsemblProtists»
0.0
GSPATT00037414001 Chromosome undetermined scaffold_169,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0CWL2_PARTE
EnsemblProtists»
0.0
GSPATT00001382001 Chromosome undetermined scaffold_3,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0D0H4_PARTE
EnsemblProtists»
0.0
GSPATT00012093001 Chromosome undetermined scaffold_33,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0DQE2_PARTE
EnsemblProtists»
0.0
GSPATT00002659001 Chromosome undetermined scaffold_6,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0DYZ0_PARTE
EnsemblProtists»
0.0
GSPATT00003225001 Chromosome undetermined scaffold_7,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A5PJ77_BOVIN
Ensembl»
0.0
MPPED2 MPPED2 protein (Metallophosphoesterase
domain containing 2)		 Bos taurus
TI:9913 None
 
A7E7M7_SCLS1
EnsemblFungi»
0.0
SS1G_01305 Calcineurin-like phosphoesterase
domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None
 
A7EPY0_SCLS1
EnsemblFungi»
0.0
SS1G_07379 Calcineurin-like phosphoesterase
domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None 		 
 
A7ETA5_SCLS1
EnsemblFungi»
0.0
SS1G_08560 Calcineurin-like phosphoesterase
domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None
 
A7F0S4_SCLS1
EnsemblFungi»
0.0
SS1G_11193 Calcineurin-like phosphoesterase
domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None 		 
 
A7F669_SCLS1
EnsemblFungi»
0.0
SS1G_13097 Calcineurin-like phosphoesterase
domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None
 
A7S2M8_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g234821 Calcineurin-like phosphoesterase
domain-containing protein		 Nematostella vectensis
TI:45351 None
 
A8J139_CHLRE
EnsemblPlants»
0.0
CHLRE_09g388171v5 Calcineurin-like phosphoesterase
domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None
 
A8WSK2_CAEBR
WormBase»
0.0
CBG03200 CBG_03200 Protein CBG03200 Caenorhabditis briggsae
TI:6238 None
 
A8XDA2_CAEBR
WormBase»
0.0
CBG11324 CBG_11324 Protein CBG11324 Caenorhabditis briggsae
TI:6238 None
 
A8XV05_CAEBR
WormBase»
0.0
CBG19177 CBG_19177 Protein CBG19177 Caenorhabditis briggsae
TI:6238 None
 
A9VCW4_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_30056 Calcineurin-like phosphoesterase
domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
A9WDE4_CHLAA
EnsemblBacteria»
0.0
Caur_3886 Metallophosphoesterase Chloroflexus aurantiacus
TI:1108 None
 
B3RKH2_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_51679 Calcineurin-like phosphoesterase
domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
B8BU60_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_21245 Calcineurin-like phosphoesterase
domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
C4LSU9_ENTH1
EnsemblProtists»
0.0
EHI_152640 Ser/thr protein phosphatase family protein Entamoeba histolytica
TI:5759 None
 
C4LVC3_ENTH1
EnsemblProtists»
0.0
EHI_197060 Ser/thr protein phosphatase family protein Entamoeba histolytica
TI:5759 None
 
C4M0P4_ENTH1
EnsemblProtists»
0.0
EHI_008800 Ser/thr protein phosphatase family protein Entamoeba histolytica
TI:5759 None
 
C4M6X4_ENTH1
EnsemblProtists»
0.0
EHI_139350 Ser/thr protein phosphatase family protein Entamoeba histolytica
TI:5759 None
 
C8V4C8_EMENI
EnsemblFungi»
0.0
ANIA_10532 Ser/Thr protein phosphatase
family protein (AFU_orthologue AFUA_1G06000)		 Emericella nidulans
TI:162425 None
 
C8VT65_EMENI
EnsemblFungi»
0.0
ANIA_00464 Ser/Thr protein phosphatase
family protein (AFU_orthologue AFUA_1G04330)		 Emericella nidulans
TI:162425 None
 
D6WGJ9_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_03443 Metallophosphoesterase domain-containing
protein 1-like Protein		 Tribolium castaneum
TI:7070 None
 
F1QUV1_DANRE
ZFIN»
0.0
mpped1 Metallophosphoesterase domain-containing 1 (Metallophosphoesterase
domain-containing protein 1 isoform X1)		 Danio rerio
TI:7955 None
 
F1SGP0_PIG
Ensembl»
0.0
MPPED2 Metallophosphoesterase MPPED2 isoform X1
(Metallophosphoesterase domain containing 2)		 Sus scrofa
TI:9823 None
 
H3GL40_PHYRM
EnsemblProtists»
0.0
Calcineurin-like phosphoesterase
domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
H3HB28_PHYRM
EnsemblProtists»
0.0
Calcineurin-like phosphoesterase
domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
M3VX47_FELCA
Ensembl»
0.0
MPPED2 Metallophosphoesterase domain containing 2 Felis catus
TI:9685 None
 
MPPD2_MOUSE
Ensembl»
4.0
Mpped2 Metallophosphoesterase MPPED2 (EC 3.1.-.-)
(Metallophosphoesterase domain-containing protein 2)		 Mus musculus
TI:10090 None
 
Q0U6I7_PHANO
EnsemblFungi»
0.0
SNOG_12627 Calcineurin-like phosphoesterase
domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
Q0UL07_PHANO
EnsemblFungi»
0.0
SNOG_07557 Calcineurin-like phosphoesterase
domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
Q0V1M7_PHANO
EnsemblFungi»
0.0
SNOG_02087 Calcineurin-like phosphoesterase
domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
Q0V588_PHANO
VEuPathDB»
0.0
SNOG_00826 Calcineurin-like phosphoesterase
domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
Q1K882_NEUCR
EnsemblFungi»
0.0
NCU01093 Ser/Thr protein phosphatase Neurospora crassa
TI:5141 None
 
Q4Q1F4_LEIMA
EnsemblProtists»
0.0
LMJF_36_2670 Calcineurin-like phosphoesterase
domain-containing protein		 Leishmania major
TI:5664 None
 
Q4WA02_ASPFU
EnsemblFungi»
0.0
AFUA_4G03130 Phosphoric ester hydrolase, putative Aspergillus fumigatus
TI:746128 None
 
Q4WJH0_ASPFU
EnsemblFungi»
0.0
AFUA_1G06000 Ser/Thr protein phosphatase family protein Aspergillus fumigatus
TI:746128 None
 
Q4WJY9_ASPFU
EnsemblFungi»
0.0
AFUA_1G04330 Ser/Thr protein phosphatase family protein Aspergillus fumigatus
TI:746128 None
 
Q4WZE3_ASPFU
EnsemblFungi»
0.0
AFUA_2G17260 Phosphoesterase, putative (EC 3.1.-.-) Aspergillus fumigatus
TI:746128 None
 
Q567D4_DANRE
ZFIN»
0.0
mpped2a Metallophosphoesterase MPPED2 (Zgc:112142) Danio rerio
TI:7955 None
 
Q5BAF4_EMENI
EnsemblFungi»
0.0
ANIA_02476 Phosphoric ester hydrolase,
putative (AFU_orthologue AFUA_4G03130)		 Emericella nidulans
TI:162425 None
 
Q7Q990_ANOGA
EnsemblMetazoa»
0.0
1275104 AGAP004891-PA Anopheles gambiae
TI:7165 None
 
Q7RWW9_NEUCR
EnsemblFungi»
0.0
NCU08795 Ser/Thr protein phosphatase Neurospora crassa
TI:5141 None
 
Q7S7M9_NEUCR
EnsemblFungi»
0.0
NCU06689 Calcineurin-like phosphoesterase
domain-containing protein		 Neurospora crassa
TI:5141 None 		 
 
Q7S9T1_NEUCR
EnsemblFungi»
0.0
NCU06375 Metallophosphoesterase domain-containing
protein 2		 Neurospora crassa
TI:5141 None
 
Q7US08_RHOBA
EnsemblBacteria»
0.0
RB5332 Probable phosphoesterase (EC 3.1.-.-) Rhodopirellula baltica
TI:265606 None
 
Q7UYQ6_RHOBA
EnsemblBacteria»
0.0
RB446 Calcineurin-like phosphoesterase
domain-containing protein		 Rhodopirellula baltica
TI:265606 None 		 
 
Q89W37_BRADU
EnsemblBacteria»
0.0
bll0856 Bll0856 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q8EZB3_LEPIN
EnsemblBacteria»
0.0
LA_3941 Phosphoesterase Leptospira interrogans
TI:173 None
 
Q9VT29_DROME
FlyBase»
0.5
Dmel\CG16717 Calcineurin-like phosphoesterase
domain-containing protein		 Drosophila melanogaster
TI:7227 None
 
Q9X7Y9_STRCO
EnsemblBacteria»
0.0
SCO2130 Calcineurin-like phosphoesterase
domain-containing protein		 Streptomyces coelicolor
TI:1902 None
 
V5IND1_NEUCR
EnsemblFungi»
0.0
NCU04147 Ser/Thr protein phosphatase Neurospora crassa
TI:5141 None
 
W5MB83_LEPOC
Ensembl»
0.0
Metallophosphoesterase domain containing 2 Lepisosteus oculatus
TI:7918 None
 
YBPT_CAEEL
WormBase»
0.0
C25E10.12 UPF0046 protein C25E10.12 Caenorhabditis elegans
TI:6239 None
 
YMSO_CAEEL
WormBase»
0.0
K07C11.7 UPF0046 protein K07C11.7 Caenorhabditis elegans
TI:6239 None
 
A0A3Q1M3T4_BOVIN
Ensembl»
0.0
MPPED1 Metallophosphoesterase domain containing 1 Bos taurus
TI:9913 None
   
A0A5F8AJX5_MACMU
Ensembl»
0.0
MPPED1 Metallophosphoesterase domain containing 1 Macaca mulatta
TI:9544 None
   
A0A7M7P634_STRPU
EnsemblMetazoa»
0.0
Calcineurin-like phosphoesterase
domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A803K3V5_XENTR
Ensembl»
0.0
mpped1 Metallophosphoesterase domain containing 1
(Metallophosphoesterase domain-containing protein 1)		 Xenopus tropicalis
TI:8364 None
   
A0A803SMV2_ANOCA
Ensembl»
0.0
MPPED1 Metallophosphoesterase domain containing 1 Anolis carolinensis
TI:28377 None
   
A0A8I3NTB0_CANLF
Ensembl»
0.0
MPPED1 Metallophosphoesterase domain containing 1 Canis lupus
TI:9612 None
   
A0A8I3QJJ0_CANLF
Ensembl»
0.0
MPPED2 Metallophosphoesterase domain containing 2 Canis lupus
TI:9612 None
   
A0A8R1UCB6_PRIPA
EnsemblMetazoa»
0.0
WBGene00101898 F-box domain-containing protein Pristionchus pacificus
TI:54126 None
   
A0A8R1Y5R6_PRIPA
EnsemblMetazoa»
0.0
WBGene00091459 Calcineurin-like phosphoesterase
domain-containing protein		 Pristionchus pacificus
TI:54126 None
   
A0A8V0Y777_CHICK
Ensembl»
0.0
MPPED1 Metallophosphoesterase domain containing 1 Gallus gallus
TI:9031 None 		     
A0A9J7HRN6_BRAFL
CTD»
0.0
LOC118406669 Metallophosphoesterase domain-containing
protein 1-like		 Branchiostoma floridae
TI:7739 None
   
D4A120_RAT
RGD»
0.0
Mpped1 Metallophosphoesterase domain containing 1 Rattus norvegicus
TI:10116 None
   
E1BXB8_CHICK
Ensembl»
0.0
MPPED2 Metallophosphoesterase domain containing 2 Gallus gallus
TI:9031 None
   
F6QLG8_CIOIN
Ensembl»
0.0
Calcineurin-like phosphoesterase
domain-containing protein		 Ciona intestinalis
TI:7719 None
   
F6WJR2_ORNAN
Ensembl»
0.0
Calcineurin-like phosphoesterase
domain-containing protein		 Ornithorhynchus anatinus
TI:9258 None
   
F7BK04_MONDO
Ensembl»
0.0
MPPED2 Metallophosphoesterase domain containing 2 Monodelphis domestica
TI:13616 None
   
F7BUC9_MONDO
Ensembl»
0.0
Metallophosphoesterase domain containing 1 Monodelphis domestica
TI:13616 None 		     
F7DY29_HORSE
Ensembl»
0.0
MPPED2 Metallophosphoesterase domain containing 2 Equus caballus
TI:9796 None
   
G1KW46_ANOCA
Ensembl»
0.0
MPPED2 Metallophosphoesterase domain containing 2 Anolis carolinensis
TI:28377 None
   
H2L538_ORYLA
Ensembl»
0.0
LOC101173128 Metallophosphoesterase MPPED2 Oryzias latipes
TI:8090 None
   
H2M871_ORYLA
Ensembl»
0.0
LOC101164611 Metallophosphoesterase domain-containing
protein 1		 Oryzias latipes
TI:8090 None
   
I3LHN0_PIG
Ensembl»
0.0
MPPED1 Metallophosphoesterase domain containing 1 Sus scrofa
TI:9823 None
   
K7EFC2_ORNAN
Ensembl»
0.0
MPPED2 Metallophosphoesterase domain containing 2 Ornithorhynchus anatinus
TI:9258 None