Collated Gene Ontology terms

Biological process: protein domain specific binding(2009, 2025) membrane curvature sensor activity(2019, 2025) small GTPase binding(2016, 2025)

Molecular function: membrane bending2018, 2025 regulation of secretion2025 neurotransmitter transport2025 regulation of neurotransmitter secretion2004, 2014, 2025 spermatid development2016 regulation of transport2025 regulation of protein-containing complex assembly2009, 2025 regulation of locomotion involved in locomotory behavior2014, 2025 dense core granule maturation2014, 2025 postsynapse organization2018
glutamate receptor clustering2018

Cellular component: cytoplasm2003, 2006, 2025 secretory granule membrane2004, 2025 endomembrane system2025 Golgi membrane2004, 2009, 2014, 2025 cytosol2004, 2024, 2025 synaptic vesicle membrane2004, 2025 acrosomal vesicle2016, 2025 cytoplasmic vesicle2025 Golgi apparatus2011, 2025 transport vesicle membrane2025
perinuclear region of cytoplasm2009, 2025 dendrite2009, 2025 Golgi stack2009, 2025 postsynapse of neuromuscular junction2018 plasma membrane2025 cytoplasmic vesicle membrane2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9VP78_DROME
FlyBase»
3.9
ICA69 GH23156p (Islet cell autoantigen 69 kDa, isoform
A) (Islet cell autoantigen 69 kDa, isoform B)		 Drosophila melanogaster
TI:7227 None
 
E1C2A8_CHICK
Ensembl»
1.5
ICA1 Islet cell autoantigen 1 Gallus gallus
TI:9031 None
   
ICA69_HUMAN
Ensembl»
2.3
ICA1 Islet cell autoantigen 1 (69 kDa islet cell
autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69)		 Homo sapiens
TI:9606 None
 
ICA69_MOUSE
Ensembl»
3.6
Ica1 Islet cell autoantigen 1 (69 kDa islet cell
autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69)		 Mus musculus
TI:10090 None
 
ICA69_RAT
RGD»
3.6
Ica1 Islet cell autoantigen 1 (69 kDa islet cell
autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69)		 Rattus norvegicus
TI:10116 None
 
Q6DHA0_DANRE
ZFIN»
1.5
ica1 Islet cell autoantigen 1 (Zgc:92566) Danio rerio
TI:7955 None
 
A0A8M3AT72_DANRE
ZFIN»
1.5
ical1 Islet cell autoantigen 1-like isoform X1
(Islet cell autoantigen 1-like protein isoform X1)		 Danio rerio
TI:7955 None
   
ICA1L_MOUSE
Ensembl»
2.3
Ica1l Islet cell autoantigen 1-like protein (Amyotrophic lateral sclerosis 2
chromosomal region candidate gene 15 protein homolog) (Ica69-related protein)		 Mus musculus
TI:10090 None
 
ICA1L_RAT
RGD»
2.0
Ica1l Islet cell autoantigen 1-like protein (Amyotrophic lateral sclerosis 2
chromosomal region candidate gene 15 protein homolog) (Ica69-related protein)		 Rattus norvegicus
TI:10116 None
 
ICA1L_HUMAN
Ensembl»
1.5
ICA1L Islet cell autoantigen 1-like protein (Amyotrophic lateral sclerosis 2 chromosomal region candidate
gene 14 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein)		 Homo sapiens
TI:9606 None
 
RIC19_CAEEL
WormBase»
4.7
ric-19 Resistance to inhibitors of
cholinesterase protein 19 (ICA1 homolog)		 Caenorhabditis elegans
TI:6239 None