Cluster UKP09615
- TRANSMEMBRANE PROTEIN 65
Standard knownness: 3.9; Custom knownness: None; Num. species: 42; Orthology database: Panther19.0; Protein members: 56
Collated Gene Ontology terms
Biological process:
calcium ion binding(2024)
hydrolase activity(2024)
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(2024)
cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(2024)
Molecular function: regulation of cardiac conduction2015, 2021, 2024 cardiac ventricle development2015, 2017, 2021, 2024 cardiac conduction2023, 2024 heart development2017
Cellular component: membrane2024 mitochondrion2009, 2012, 2014, 2018, 2021, 2024 mitochondrial inner membrane2017, 2024 plasma membrane2015, 2024 intercalated disc2015, 2024 cytoplasm2018
Phylogenetic distribution
| Chordates: | 20/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 4/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 1/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 0/3 | |
| Excavates: | 2/4 | |
| Harosa: | 3/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 5/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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G1KJI6_ANOCA Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Anolis carolinensis TI:28377 None |
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A0A1S4H0M7_ANOGA EnsemblMetazoa» |
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Uncharacterized protein |
Anopheles gambiae TI:7165 None |
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TMM65_BOVIN Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Bos taurus TI:9913 None |
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A0A9J7HG99_BRAFL CTD» |
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LOC118403985 | Transmembrane protein 65-like |
Branchiostoma floridae TI:7739 None |
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A8XRJ9_CAEBR WormBase» |
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Cbr-tag-321 | Protein CBR-TAG-321 |
Caenorhabditis briggsae TI:6238 None |
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B6IEE2_CAEBR WormBase» |
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CBG26048 CBG_26048 | Protein CBG26048 |
Caenorhabditis briggsae TI:6238 None |
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Q95QS6_CAEEL WormBase» |
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tag-321 | Transmembrane protein 65 |
Caenorhabditis elegans TI:6239 None |
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YPB3_CAEEL WormBase» |
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C03B8.3 | Uncharacterized protein C03B8.3 |
Caenorhabditis elegans TI:6239 None |
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Q84X76_CHLRE EnsemblPlants» |
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CHLRE_03g171550v5 | CR042 protein |
Chlamydomonas reinhardtii TI:3055 None |
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F6Y7W5_CIOIN Ensembl» |
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LOC100184985 | Transmembrane protein 65-like |
Ciona intestinalis TI:7719 None |
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TMM65_DANRE ZFIN» |
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tmem65 | Transmembrane protein 65 |
Danio rerio TI:7955 None |
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E9H326_DAPPU EnsemblMetazoa» |
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DAPPUDRAFT_200404 | Transmembrane protein 65 |
Daphnia pulex TI:6669 None |
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Q8SYF7_DROME FlyBase» |
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Dmel\CG17715 | LP09246p (RE07178p) (RE63764p) (Uncharacterized protein, isoform B) (Uncharacterized protein, isoform D) |
Drosophila melanogaster TI:7227 None |
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A0A3Q2KU82_HORSE Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Equus caballus TI:9796 None |
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A0A337SHV8_FELCA Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Felis catus TI:9685 None |
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A0A8V0Y889_CHICK Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Gallus gallus TI:9031 None |
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A0A2I2ZLW7_GORGO Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Gorilla gorilla TI:9593 None |
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T1G9T8_HELRO EnsemblMetazoa» |
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20217834 | Transmembrane protein 65 |
Helobdella robusta TI:6412 None |
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TMM65_HUMAN Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Homo sapiens TI:9606 None |
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A0A1Y1I4M4_KLENI EnsemblPlants» |
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KFL_001580010 | EF-hand domain-containing protein |
Klebsormidium nitens TI:105231 None |
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Q4Q071_LEIMA EnsemblProtists» |
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LMJF_36_6840 | EF-hand domain-containing protein |
Leishmania major TI:5664 None |
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Q4QI72_LEIMA EnsemblProtists» |
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LMJF_08_0970 | EF-hand domain-containing protein |
Leishmania major TI:5664 None |
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W5MRE8_LEPOC Ensembl» |
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Transmembrane protein 65 |
Lepisosteus oculatus TI:7918 None |
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A0A5F7Z7C1_MACMU Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Macaca mulatta TI:9544 None |
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A0A2R6XF70_MARPO EnsemblPlants» |
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MARPO_0019s0161 | EF-hand domain-containing protein |
Marchantia polymorpha TI:3197 None |
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F6SNF7_MONDO Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Monodelphis domestica TI:13616 None |
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A9UV59_MONBE EnsemblProtists» |
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MONBRDRAFT_23897 | EF-hand domain-containing protein |
Monosiga brevicollis TI:81824 None |
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TMM65_MOUSE Ensembl» |
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Tmem65 | Transmembrane protein 65 |
Mus musculus TI:10090 None |
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A7RM83_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g86363 | Transmembrane protein 65 |
Nematostella vectensis TI:45351 None |
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H2L4U2_ORYLA Ensembl» |
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LOC111948219 | Transmembrane protein 65 |
Oryzias latipes TI:8090 None |
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H2LJQ1_ORYLA Ensembl» |
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LOC101157639 | Transmembrane protein 65 |
Oryzias latipes TI:8090 None |
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K7C6R4_PANTR Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Pan troglodytes TI:9598 None |
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A9SM92_PHYPA EnsemblPlants» |
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EF-hand domain-containing protein |
Physcomitrium patens TI:3218 None |
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H3G5D7_PHYRM EnsemblProtists» |
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Transmembrane protein 65 |
Phytophthora ramorum TI:164328 None |
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H3GUD1_PHYRM EnsemblProtists» |
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EF-hand domain-containing protein |
Phytophthora ramorum TI:164328 None |
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A0A143ZYV4_PLAF7 EnsemblProtists» |
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PF3D7_1145600 | TMEM65 domain-containing protein, putative |
Plasmodium falciparum TI:5833 None |
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O96195_PLAF7 EnsemblProtists» |
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PF3D7_0211500 | GAF domain-related protein, putative |
Plasmodium falciparum TI:5833 None |
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A0A2A6CIL6_PRIPA EnsemblMetazoa» |
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WBGene00114902 | Uncharacterized protein |
Pristionchus pacificus TI:54126 None |
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A0A8R1U972_PRIPA EnsemblMetazoa» |
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WBGene00103181 | Transmembrane protein 65 |
Pristionchus pacificus TI:54126 None |
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A0A8I5ZUG0_RAT RGD» |
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ENSRNOG00000067321 | Uncharacterized protein |
Rattus norvegicus TI:10116 None |
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A0A8I6A4F9_RAT RGD» |
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ENSRNOG00000069664 | Uncharacterized protein |
Rattus norvegicus TI:10116 None |
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A0A8I6AVM0_RAT RGD» |
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Tmem65 | Transmembrane protein 65 |
Rattus norvegicus TI:10116 None |
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D8RT42_SELML EnsemblPlants» |
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SELMODRAFT_7963 SELMODRAFT_7967 | Uncharacterized protein |
Selaginella moellendorffii TI:88036 None |
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A0A7M7RGY4_STRPU EnsemblMetazoa» |
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Transmembrane protein 65 |
Strongylocentrotus purpuratus TI:7668 None |
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A0A287BIG1_PIG Ensembl» |
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TMEM65 | Transmembrane protein 65 |
Sus scrofa TI:9823 None |
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B5YLF7_THAPS EnsemblProtists» |
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THAPS_269927 | GAF domain-containing protein (EC 3.1.4.17) |
Thalassiosira pseudonana TI:35128 None |
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B8C1S1_THAPS EnsemblProtists» |
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THAPSDRAFT_262395 | GAF domain-containing protein |
Thalassiosira pseudonana TI:35128 None |
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B8C9L6_THAPS EnsemblProtists» |
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THAPSDRAFT_18158 | Transmembrane protein 65 |
Thalassiosira pseudonana TI:35128 None |
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D6X0I0_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_11682 | Transmembrane protein 65-like Protein |
Tribolium castaneum TI:7070 None |
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B3S2M6_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_58081 | Transmembrane protein 65 |
Trichoplax adhaerens TI:10228 None |
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Q38AF3_TRYB2 VEuPathDB» |
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Tb10.6k15.2410 | Transmembrane protein 65 |
Trypanosoma brucei TI:5691 None |
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Q57ZW2_TRYB2 VEuPathDB» |
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Tb05.26K5.360 | EF-hand domain-containing protein |
Trypanosoma brucei TI:5691 None |
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A0A1L8FZY3_XENLA Xenbase» |
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tmem65.L | Transmembrane protein 65 isoform X2 |
Xenopus laevis TI:8355 None |
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A0A8J1L0P8_XENLA CTD» |
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LOC108719407 | Transmembrane protein 65 isoform X1 |
Xenopus laevis TI:8355 None |
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A0A8J1L4Q2_XENLA Xenbase» |
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LOC108719760 | Transmembrane protein 65 isoform X1 |
Xenopus laevis TI:8355 None |
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B1H2M3_XENTR Xenbase» |
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tmem65 | LOC100145439 protein (Transmembrane protein 65) |
Xenopus tropicalis TI:8364 None |
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