Collated Gene Ontology terms

Biological process: calcium ion binding(2013, 2024) metal ion binding(2024)

Molecular function: vesicle-mediated transport2024 regulation of cell cycle2024 protein transport2024 cell adhesion2024 carboxylic acid metabolic process2003 sexual reproduction2013 negative regulation of cell population proliferation2003 negative regulation of cell growth2005

Cellular component: extracellular region2003, 2024 endoplasmic reticulum-Golgi intermediate compartment2024 endoplasmic reticulum2024 Golgi apparatus2024 extracellular space2012 endoplasmic reticulum-Golgi intermediate compartment membrane2015 endoplasmic reticulum membrane2015 ER to Golgi transport vesicle membrane2013

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
G1KCN9_ANOCA
Ensembl»
0.0
MCFD2 Multiple coagulation factor deficiency 2,
ER cargo receptor complex subunit		 Anolis carolinensis
TI:28377 None
   
A0A1S4GR51_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
Q7Q7Q7_ANOGA
EnsemblMetazoa»
0.0
1275900 AGAP004631-PA Anopheles gambiae
TI:7165 None
 
F4P3U4_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_25195 EF-hand domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
A0A3Q1MFL2_BOVIN
Ensembl»
0.0
MCFD2 Multiple coagulation factor deficiency 2,
ER cargo receptor complex subunit		 Bos taurus
TI:9913 None
   
A0A3Q1MH68_BOVIN
Ensembl»
0.0
Uncharacterized protein Bos taurus
TI:9913 None
   
A0A9J7HL12_BRAFL
CTD»
0.0
LOC118404728 Multiple coagulation factor deficiency protein 2 homolog isoform X1
(Multiple coagulation factor deficiency protein 2 homolog isoform X2)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7LZ26_BRAFL
CTD»
0.0
LOC118425908 Multiple coagulation factor
deficiency protein 2 homolog		 Branchiostoma floridae
TI:7739 None 		     
A0A9J7N3Y5_BRAFL
CTD»
0.0
LOC118425906 Multiple coagulation factor deficiency
protein 2 homolog isoform X1		 Branchiostoma floridae
TI:7739 None 		     
C3XRX8_BRAFL
CTD»
0.0
LOC118415270 Cell growth regulator with
EF hand domain protein 1-like		 Branchiostoma floridae
TI:7739 None
 
C3XRY0_BRAFL
CTD»
0.0
Prop Multiple coagulation factor
deficiency protein 2 homolog		 Branchiostoma floridae
TI:7739 None 		 
 
A8XF67_CAEBR
WormBase»
0.0
CBG12288 CBG_12288 Protein CBG12288 Caenorhabditis briggsae
TI:6238 None
 
A8Y4B0_CAEBR
WormBase»
0.0
CBG23273 CBG_23273 Protein CBG23273 Caenorhabditis briggsae
TI:6238 None
 
Q20796_CAEEL
WormBase»
0.0
CELE_F55A11.1 F55A11.1 EF-hand domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q22159_CAEEL
WormBase»
0.0
CELE_T04F3.4 T04F3.4 EF-hand domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q3HKD3_CAEEL
WormBase»
0.0
C29E4.14 CELE_C29E4.14 EF-hand domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A0A8I3MXZ8_CANLF
Ensembl»
0.0
CGREF1 Uncharacterized protein Canis lupus
TI:9612 None
   
A0A8I3Q3Y7_CANLF
Ensembl»
0.0
MCFD2 EF-hand domain-containing protein Canis lupus
TI:9612 None
   
H2XXY9_CIOIN
Ensembl»
0.0
EF-hand domain-containing protein Ciona intestinalis
TI:7719 None
 
F6P9I0_DANRE
ZFIN»
0.0
cgref1 Cell growth regulator with EF hand domain protein
1 (Cell growth regulator with EF-hand domain 1)		 Danio rerio
TI:7955 None
 
Q5XJ39_DANRE
ZFIN»
0.0
hm:zeh1186 Mcfd2 protein (Multiple coagulation factor deficiency 2) (Multiple coagulation factor deficiency 2,
ER cargo receptor complex subunit) (Multiple coagulation factor deficiency protein 2 precursor)		 Danio rerio
TI:7955 None
 
E9FS66_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_205163 EF-hand domain-containing protein Daphnia pulex
TI:6669 None
 
E9GYK7_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_306762 EF-hand domain-containing protein Daphnia pulex
TI:6669 None
 
Q0KI91_DROME
FlyBase»
0.0
Dmel\CG12817 EF-hand domain-containing protein Drosophila melanogaster
TI:7227 None
 
Q9VDI5_DROME
FlyBase»
1.3
Dmel\CG17271 Uncharacterized protein, isoform A Drosophila melanogaster
TI:7227 None
 
F7DNX7_HORSE
Ensembl»
0.0
MCFD2 Multiple coagulation factor deficiency 2,
ER cargo receptor complex subunit		 Equus caballus
TI:9796 None
   
A0A2I2ULQ3_FELCA
Ensembl»
0.0
EF-hand domain-containing protein Felis catus
TI:9685 None
 
A0A337S3T7_FELCA
Ensembl»
0.0
Multiple coagulation factor deficiency 2,
ER cargo receptor complex subunit		 Felis catus
TI:9685 None 		 
 
M3WCB0_FELCA
Ensembl»
0.0
CGREF1 Cell growth regulator with EF-hand domain 1 Felis catus
TI:9685 None
 
A0A8V0Y4R8_CHICK
Ensembl»
0.0
CGREF1 EF-hand domain-containing protein Gallus gallus
TI:9031 None
   
Q5ZJB5_CHICK
Ensembl»
0.0
MCFD2 Multiple coagulation factor deficiency 2 Gallus gallus
TI:9031 None
 
G3QJG5_GORGO
Ensembl»
0.0
Cell growth regulator with EF-hand domain 1 Gorilla gorilla
TI:9593 None
 
G3R986_GORGO
Ensembl»
0.0
MCFD2 Multiple coagulation factor deficiency 2,
ER cargo receptor complex subunit		 Gorilla gorilla
TI:9593 None
 
T1FQ28_HELRO
EnsemblMetazoa»
0.0
20210925 EF-hand domain-containing protein Helobdella robusta
TI:6412 None
 
T1FS13_HELRO
EnsemblMetazoa»
0.0
20211610 EF-hand domain-containing protein Helobdella robusta
TI:6412 None 		 
 
CGRE1_HUMAN
Ensembl»
0.9
CGREF1 Cell growth regulator with EF hand domain protein
1 (Cell growth regulatory gene 11 protein) (Hydrophobestin)		 Homo sapiens
TI:9606 None
 
MCFD2_HUMAN
Ensembl»
0.0
MCFD2 Multiple coagulation factor deficiency protein 2
(Neural stem cell-derived neuronal survival protein)		 Homo sapiens
TI:9606 None
 
B7P2K4_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW000865 EF hand domain-containing protein, putative
(EF hand domain-containing protein, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
B7Q8D4_IXOSC
EnsemblMetazoa»
0.0
8037429 EF hand domain-containing protein, putative Ixodes scapularis
TI:6945 None
 
B7Q8D5_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW010588 Mcfdp2, putative Ixodes scapularis
TI:6945 None 		 
 
B7Q8D6_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW010589 EF hand domain-containing protein, putative Ixodes scapularis
TI:6945 None 		 
 
W5LX64_LEPOC
Ensembl»
0.0
Cell growth regulator with EF-hand domain 1 Lepisosteus oculatus
TI:7918 None
   
W5NHP2_LEPOC
Ensembl»
0.0
Multiple coagulation factor deficiency 2 Lepisosteus oculatus
TI:7918 None
 
A0A1D5QCQ7_MACMU
Ensembl»
0.0
MCFD2 Multiple coagulation factor deficiency 2,
ER cargo receptor complex subunit		 Macaca mulatta
TI:9544 None
   
F7GPR1_MACMU
Ensembl»
0.0
CGREF1 Cell growth regulator with EF-hand domain 1 Macaca mulatta
TI:9544 None
   
F6ZFJ6_MONDO
Ensembl»
0.0
MCFD2 Multiple coagulation factor deficiency 2 Monodelphis domestica
TI:13616 None
   
F7B5N9_MONDO
Ensembl»
0.0
EF-hand domain-containing protein Monodelphis domestica
TI:13616 None
   
CGRE1_MOUSE
AG»
0.0
Cgref1 Cell growth regulator with EF hand domain protein
1 (Cell growth regulatory gene 11 protein) (Hydrophobestin)		 Mus musculus
TI:10090 None
 
MCFD2_MOUSE
Ensembl»
0.5
Mcfd2 Multiple coagulation factor deficiency protein 2
homolog (Neural stem cell-derived neuronal survival protein)		 Mus musculus
TI:10090 None
 
A7SFP6_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g116525 EF-hand domain-containing protein Nematostella vectensis
TI:45351 None
 
A7SIS2_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g245530 EF-hand domain-containing protein Nematostella vectensis
TI:45351 None
 
A0A6I8NL41_ORNAN
Ensembl»
0.0
EF-hand domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8PCT8_ORNAN
Ensembl»
0.0
EF-hand domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A3B3IPK9_ORYLA
Ensembl»
0.0
mcfd2 Multiple coagulation factor deficiency 2 Oryzias latipes
TI:8090 None
   
H2M5X7_ORYLA
Ensembl»
0.0
cgref1 Cell growth regulator with EF-hand domain 1 Oryzias latipes
TI:8090 None
   
A0A2I3SM22_PANTR
Ensembl»
0.0
CGREF1 Cell growth regulator with EF-hand domain 1 Pan troglodytes
TI:9598 None
 
H2QHV6_PANTR
Ensembl»
0.0
MCFD2 Multiple coagulation factor deficiency 2 (Multiple coagulation
factor deficiency 2, ER cargo receptor complex subunit)		 Pan troglodytes
TI:9598 None
 
A0A2A6BWD5_PRIPA
EnsemblMetazoa»
0.0
WBGene00278602 EF-hand domain-containing protein Pristionchus pacificus
TI:54126 None
 
A0A2A6CGZ8_PRIPA
EnsemblMetazoa»
0.0
WBGene00117553 HLH domain-containing protein Pristionchus pacificus
TI:54126 None
 
A0A8R1ZBZ1_PRIPA
EnsemblMetazoa»
0.0
WBGene00304619 EF-hand domain-containing protein Pristionchus pacificus
TI:54126 None
   
A0A8I5ZKM6_RAT
RGD»
0.0
ENSRNOG00000068749 Uncharacterized protein Rattus norvegicus
TI:10116 None 		     
CGRE1_RAT
RGD»
0.8
Cgref1 Cell growth regulator with EF hand domain protein
1 (Cell growth regulatory gene 11 protein) (Hydrophobestin)		 Rattus norvegicus
TI:10116 None
 
MCFD2_RAT
RGD»
0.8
Mcfd2 Multiple coagulation factor deficiency protein 2
homolog (Neural stem cell-derived neuronal survival protein)		 Rattus norvegicus
TI:10116 None
 
A0A7M7G0V2_STRPU
EnsemblMetazoa»
0.0
Multiple coagulation factor
deficiency protein 2 homolog		 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A7M7T5G7_STRPU
EnsemblMetazoa»
0.0
EF-hand domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
F1SEC5_PIG
Ensembl»
0.0
CGREF1 Cell growth regulator with EF-hand domain 1 Sus scrofa
TI:9823 None
   
K7GQY4_PIG
Ensembl»
0.0
MCFD2 Multiple coagulation factor deficiency 2,
ER cargo receptor complex subunit		 Sus scrofa
TI:9823 None
   
D2A071_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_08169 Multiple coagulation factor deficiency
protein 2 homolog-like Protein		 Tribolium castaneum
TI:7070 None 		 
 
D6W6V5_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_14175 Multiple coagulation factor deficiency
protein 2 homolog-like Protein		 Tribolium castaneum
TI:7070 None
 
B3S2Z7_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_58542 EF-hand domain-containing protein Trichoplax adhaerens
TI:10228 None 		 
 
B3S580_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_59229 EF-hand domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B3S581_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_59230 EF-hand domain-containing protein Trichoplax adhaerens
TI:10228 None
 
A0A1L8G5N3_XENLA
Xenbase»
0.0
cgref1.S Cell growth regulator with EF
hand domain protein 1 isoform X1		 Xenopus laevis
TI:8355 None
   
A0A803J5X3_XENTR
Xenbase»
0.0
mcfd2 Multiple coagulation factor deficiency 2 (Multiple
coagulation factor deficiency protein 2 isoform X1)		 Xenopus tropicalis
TI:8364 None
   
A0A8J0R4W4_XENTR
Xenbase»
0.0
LOC101735296 Multiple coagulation factor
deficiency protein 2 homolog		 Xenopus tropicalis
TI:8364 None
   
A0A8J0V9K1_XENLA
Xenbase»
0.0
cgref1.L Cell growth regulator with
EF hand domain protein 1		 Xenopus laevis
TI:8355 None
   
A0A8J1JIT8_XENTR
Xenbase»
0.0
cgref1 Cell growth regulator with
EF hand domain protein 1		 Xenopus tropicalis
TI:8364 None
   
A0A8J1KQY0_XENLA
Xenbase»
0.0
LOC121393651 Multiple coagulation factor deficiency
protein 2 homolog isoform X1		 Xenopus laevis
TI:8355 None
   
A9ULX1_XENLA
Xenbase»
0.0
mcfd2.S LOC100137636 protein (Multiple coagulation factor
deficiency 2 L homeolog precursor)		 Xenopus laevis
TI:8355 None
 
Q6DFB1_XENLA
Xenbase»
0.0
mcfd2.L MGC83844 protein (MGC83844 protein precursor) Xenopus laevis
TI:8355 None