Collated Gene Ontology terms

Biological process: transmembrane transporter activity(2024) MHC class I receptor activity(2018) MHC class I protein binding(2018) zinc ion binding(2024) serine-type endopeptidase inhibitor activity(2024) protein kinase activity(2024) metallocarboxypeptidase activity(2024) calcium ion binding(2024) DNA-binding transcription factor activity(2024) ATP binding(2024)

Molecular function: transmembrane transport2024 antigen processing and presentation of exogenous peptide antigen via MHC class I2018, 2020, 2024 synaptic vesicle exocytosis2021, 2024 regulation of DNA-templated transcription2024 proteolysis2024 protein phosphorylation2024 envenomation resulting in negative regulation of voltage-gated potassium channel activity in another organism2024 determination of adult lifespan2006 adaptive immune response2024

Cellular component: membrane2014, 2020, 2024 plasma membrane2018, 2020, 2024 synaptic vesicle2021, 2024 nucleus2024

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
MFSD6_HUMAN
Ensembl»
0.5
MFSD6 Major facilitator superfamily domain-containing protein 6
(Macrophage MHC class I receptor 2 homolog)		 Homo sapiens
TI:9606 None
 
Q8MRB2_DROME
FlyBase»
1.0
Dmel\CG15706 RE36877p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Uncharacterized
protein, isoform D) (Uncharacterized protein, isoform E) (Uncharacterized protein, isoform F)		 Drosophila melanogaster
TI:7227 None
 
Q0E8H7_DROME
FlyBase»
1.0
SP1173 FI19426p1 (SP1173, isoform A) (SP1173, isoform
B) (SP1173, isoform C) (SP1173, isoform D)		 Drosophila melanogaster
TI:7227 None
 
MFSD6_MOUSE
Ensembl»
2.4
Mfsd6 Major facilitator superfamily domain-containing protein 6
(Macrophage MHC class I receptor 2)		 Mus musculus
TI:10090 None
 
MFS6L_HUMAN
Ensembl»
0.0
MFSD6L Major facilitator superfamily
domain-containing protein 6-like		 Homo sapiens
TI:9606 None
 
Q9VQ52_DROME
FlyBase»
1.0
CG15359 GH27779p (Uncharacterized protein, isoform
A) (Uncharacterized protein, isoform C)		 Drosophila melanogaster
TI:7227 None
 
A1Z9U2_DROME
FlyBase»
1.0
jef Jet fuel, isoform A (Jet fuel, isoform B) Drosophila melanogaster
TI:7227 None
 
MFD6A_DANRE
ZFIN»
0.5
mfsd6a Major facilitator superfamily domain-containing protein 6-A (Macrophage
MHC class I receptor 2 homolog A)		 Danio rerio
TI:7955 None
 
MFD6B_DANRE
ZFIN»
0.5
mfsd6b Major facilitator superfamily domain-containing protein 6-B (Macrophage
MHC class I receptor 2 homolog B)		 Danio rerio
TI:7955 None
 
MFS6L_DANRE
ZFIN»
0.0
mfsd6l Major facilitator superfamily
domain-containing protein 6-like		 Danio rerio
TI:7955 None
 
MFS6L_MOUSE
Ensembl»
0.0
Mfsd6l Major facilitator superfamily
domain-containing protein 6-like		 Mus musculus
TI:10090 None
 
Q54G39_DICDI
dictyBase»
0.0
DDB_G0290423 Major facilitator superfamily
associated domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q55CH3_DICDI
dictyBase»
0.0
DDB_G0270720 Major facilitator superfamily
associated domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q55F73_DICDI
dictyBase»
0.0
DDB_G0268230 Major facilitator superfamily
associated domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q95Y88_CAEEL
WormBase»
0.8
mfsd-6 Major facilitator superfamily
associated domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q9VTL9_DROME
FlyBase»
1.8
Sugb Sugar baby, isoform C Drosophila melanogaster
TI:7227 None
 
A0A8V0YAM6_CHICK
Ensembl»
0.0
MFSD6 Major facilitator superfamily
domain containing 6		 Gallus gallus
TI:9031 None
   
D3ZCJ3_RAT
RGD»
2.0
Mfsd6 Major facilitator superfamily
domain containing 6		 Rattus norvegicus
TI:10116 None
   
D4A757_RAT
RGD»
0.0
Mfsd6l Major facilitator superfamily
domain containing 6-like		 Rattus norvegicus
TI:10116 None