Cluster UKP09175
- GAMMA-SECRETASE-ACTIVATING PROTEIN
Standard knownness: 2.9; Custom knownness: None; Num. species: 28; Orthology database: Panther19.0; Protein members: 28
Collated Gene Ontology terms
Biological process:
amyloid-beta binding(2010, 2024)
Molecular function: positive regulation of amyloid-beta formation2014, 2020, 2024 regulation of proteolysis2010, 2024
Cellular component: trans-Golgi network2010, 2020, 2024 Golgi apparatus2024
Phylogenetic distribution
| Chordates: | 20/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 0/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 0/3 | |
| Arthropods: | 3/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 0/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 1/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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G1KF73_ANOCA Ensembl» |
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GSAP | Gamma-secretase activating protein |
Anolis carolinensis TI:28377 None |
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A0A1S4GZI6_ANOGA EnsemblMetazoa» |
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Pigeon protein |
Anopheles gambiae TI:7165 None |
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A0A3Q1MCR2_BOVIN Ensembl» |
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GSAP | Gamma-secretase activating protein |
Bos taurus TI:9913 None |
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A0A9J7MR94_BRAFL CTD» |
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LOC118415690 | Gamma-secretase-activating protein-like isoform X1 |
Branchiostoma floridae TI:7739 None |
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A0A8I3PH70_CANLF Ensembl» |
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GSAP | Gamma-secretase activating protein |
Canis lupus TI:9612 None |
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A0A8M2BC42_DANRE CTD» |
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gsap | Gamma-secretase-activating protein isoform X1 |
Danio rerio TI:7955 None |
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F0ZG18_DICPU EnsemblProtists» |
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DICPUDRAFT_150327 | Gamma-secretase-activating protein C-terminal domain-containing protein |
Dictyostelium purpureum TI:5786 None |
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Q54MT3_DICDI dictyBase» |
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DDB_G0285677 | Gamma-secretase-activating protein C-terminal domain-containing protein |
Dictyostelium discoideum TI:44689 None |
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PIGE_DROME FlyBase» |
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pigeon | Protein pigeon (Protein linotte) |
Drosophila melanogaster TI:7227 None |
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M3WTF6_FELCA Ensembl» |
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GSAP | Gamma-secretase activating protein |
Felis catus TI:9685 None |
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A0A8V0Y263_CHICK Ensembl» |
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GSAP | Gamma-secretase activating protein |
Gallus gallus TI:9031 None |
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G3SKK1_GORGO Ensembl» |
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GSAP | Gamma-secretase activating protein |
Gorilla gorilla TI:9593 None |
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GSAP_HUMAN Ensembl» |
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GSAP | Gamma-secretase-activating protein (GSAP) (Protein pigeon homolog) [Cleaved into: Gamma-secretase-activating protein 16 kDa C-terminal form (GSAP-16K)] |
Homo sapiens TI:9606 None |
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W5NGE4_LEPOC Ensembl» |
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Gamma-secretase activating protein |
Lepisosteus oculatus TI:7918 None |
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A0A5F8A9D0_MACMU Ensembl» |
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GSAP | Gamma-secretase activating protein |
Macaca mulatta TI:9544 None |
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F6QD55_MONDO Ensembl» |
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GSAP | Gamma-secretase activating protein |
Monodelphis domestica TI:13616 None |
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A9UQE9_MONBE EnsemblProtists» |
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MONBRDRAFT_22382 | Gamma-secretase-activating protein C-terminal domain-containing protein |
Monosiga brevicollis TI:81824 None |
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GSAP_MOUSE Ensembl» |
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Gsap | Gamma-secretase-activating protein (GSAP) (Protein pigeon homolog) [Cleaved into: Gamma-secretase-activating protein 16 kDa C-terminal form (GSAP-16K)] |
Mus musculus TI:10090 None |
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A7RFW0_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g237945 | Gamma-secretase-activating protein C-terminal domain-containing protein |
Nematostella vectensis TI:45351 None |
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A0A6I8PQB5_ORNAN Ensembl» |
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GSAP | Gamma-secretase activating protein |
Ornithorhynchus anatinus TI:9258 None |
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A0A3B3HNG7_ORYLA Ensembl» |
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gsap | Gamma-secretase activating protein |
Oryzias latipes TI:8090 None |
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H2QUT9_PANTR Ensembl» |
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GSAP | Gamma-secretase activating protein (Pigeon homolog) |
Pan troglodytes TI:9598 None |
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A0A0G2JWZ3_RAT RGD» |
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Gsap | Gamma-secretase activating protein |
Rattus norvegicus TI:10116 None |
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A0A7M7HK62_STRPU EnsemblMetazoa» |
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Gamma-secretase-activating protein C-terminal domain-containing protein |
Strongylocentrotus purpuratus TI:7668 None |
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A0A5G2RBF0_PIG Ensembl» |
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GSAP | Gamma-secretase activating protein |
Sus scrofa TI:9823 None |
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D6W882_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_01724 | Protein pigeon-like Protein |
Tribolium castaneum TI:7070 None |
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A0A1L8GZA0_XENLA Xenbase» |
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gsap.L | Gamma-secretase-activating protein |
Xenopus laevis TI:8355 None |
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A0A803K2I1_XENTR Ensembl» |
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gsap | Gamma-secretase activating protein (Gamma-secretase-activating protein isoform X1) |
Xenopus tropicalis TI:8364 None |
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