Collated Gene Ontology terms

Biological process: phospholipid scramblase activity(2025) L-amino acid transmembrane transporter activity(2024)

Molecular function: phospholipid translocation2017, 2018, 2025 retrograde transport, endosome to Golgi2017, 2018, 2025 plasma membrane phospholipid scrambling2025 multivesicular body assembly2025 lipid transport2025 amino acid transmembrane transport2024 L-alpha-amino acid transmembrane transport2025

Cellular component: membrane2025 trans-Golgi network membrane2019, 2025 endosome membrane2019, 2025 cytosol2025 trans-Golgi network2025 endosome2025 early endosome2025 lysosomal membrane2024 late endosome membrane2025 endoplasmic reticulum2018
cytoplasm2018 Golgi membrane2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 11/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 3/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A803TNQ7_ANOCA
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Anolis carolinensis
TI:28377 None
   
A0A1S4GZE5_ANOGA
EnsemblMetazoa»
0.0
Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Anopheles gambiae
TI:7165 None
 
Q4WEM2_ASPFU
TubercuList»
0.0
AFUA_5G03510 PQ loop repeat protein Aspergillus fumigatus
TI:746128 None
 
S66A2_BOVIN
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Bos taurus
TI:9913 None
 
A0A9J7MUM1_BRAFL
neXtProt»
0.0
LOC118418625 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Branchiostoma floridae
TI:7739 None
   
A8WW26_CAEBR
WormBase»
0.0
CBG04043 CBG_04043 Protein CBG04043 Caenorhabditis briggsae
TI:6238 None
 
A8WW28_CAEBR
CTD»
0.0
CBG04045 CBG_04045 Protein CBG04045 Caenorhabditis briggsae
TI:6238 None
 
G5EE99_CAEEL
WormBase»
1.0
CELE_T19A6.1 T19A6.1 PQ-loop repeat-containing protein 1 Caenorhabditis elegans
TI:6239 None
 
A0A1D8PDB8_CANAL
CGD»
0.0
CAALFM_C104340CA orf19.8672 PQ-loop repeat-containing protein 1 Candida albicans
TI:5476 None
 
A0A8I3M9N7_CANLF
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Canis lupus
TI:9612 None
   
A0A1W3JHQ5_CIOIN
Ensembl»
0.0
LOC100176476 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Ciona intestinalis
TI:7719 None
   
Q5KI27_CRYD1
TubercuList»
0.0
CND04440 PQ-loop repeat-containing protein 1 Cryptococcus deneoformans
TI:40410 None
 
A0A8M9PH02_DANRE
ZFIN»
1.0
slc66a2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Danio rerio
TI:7955 None
   
A3KQM5_DANRE
ZFIN»
1.0
si:dkey-246g23.2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Danio rerio
TI:7955 None
 
Q54C20_DICDI
dictyBase»
1.0
DDB_G0293284 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Dictyostelium discoideum
TI:44689 None
 
M9PEZ6_DROME
FlyBase»
2.0
BcDNA:SD10385 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Drosophila melanogaster
TI:7227 None
 
C8V783_EMENI
TubercuList»
0.0
ANIA_11057 Uncharacterized protein Emericella nidulans
TI:162425 None
 
C4LSG6_ENTH1
TubercuList»
0.0
EHI_151230 PQ loop repeat protein Entamoeba histolytica
TI:5759 None
 
A0A5F5Q339_HORSE
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Equus caballus
TI:9796 None
   
Q75A96_EREGS
neXtProt»
0.0
AGOS_ADR022W ADR022Wp Eremothecium gossypii
TI:33169 None
 
A0ABI7VTC9_FELCA
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Felis catus
TI:9685 None
   
A0A3Q2U1K3_CHICK
Ensembl»
0.0
PQLC1 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Gallus gallus
TI:9031 None
   
G3QRC5_GORGO
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Gorilla gorilla
TI:9593 None
 
T1EHM2_HELRO
EnsemblMetazoa»
0.0
20196072 PQ-loop repeat-containing protein 1 Helobdella robusta
TI:6412 None
 
S66A2_HUMAN
Ensembl»
1.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Homo sapiens
TI:9606 None
 
B7PRS3_IXOSC
EnsemblMetazoa»
0.0
8030412 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Ixodes scapularis
TI:6945 None
 
Q4Q8Y8_LEIMA
TubercuList»
0.0
LMJF_26_2040 PQ loop repeat family protein Leishmania major
TI:5664 None
 
W5M2Q3_LEPOC
Ensembl»
0.0
Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Lepisosteus oculatus
TI:7918 None
 
W5MPF3_LEPOC
Ensembl»
0.0
Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Lepisosteus oculatus
TI:7918 None
 
F7GUY0_MACMU
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Macaca mulatta
TI:9544 None
 
F7B9T8_MONDO
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Monodelphis domestica
TI:13616 None
   
S66A2_MOUSE
Ensembl»
1.0
Slc66a2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Mus musculus
TI:10090 None
 
A7SL76_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g14428 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Nematostella vectensis
TI:45351 None
 
Q7S2B8_NEUCR
TubercuList»
0.0
NCU09543 PQ loop repeat protein Neurospora crassa
TI:5141 None
 
A0A6I8N5D4_ORNAN
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Ornithorhynchus anatinus
TI:9258 None
   
A0A3B3IC47_ORYLA
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Oryzias latipes
TI:8090 None
   
H2MM41_ORYLA
Ensembl»
0.0
si:dkey-246g23.2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Oryzias latipes
TI:8090 None
   
H2QER2_PANTR
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Pan troglodytes
TI:9598 None
 
A0CKI6_PARTE
neXtProt»
0.0
GSPATT00001017001 PQ-loop repeat-containing protein Paramecium tetraurelia
TI:5888 None
 
A0CNM7_PARTE
neXtProt»
0.0
GSPATT00008836001 PQ-loop repeat-containing protein Paramecium tetraurelia
TI:5888 None
 
A0A7U2FKR4_PHANO
TubercuList»
0.0
JI435_110530 PQ loop repeat protein Phaeosphaeria nodorum
TI:13684 None
 
A0A2A6BUG2_PRIPA
EnsemblMetazoa»
0.0
WBGene00094699 Uncharacterized protein Pristionchus pacificus
TI:54126 None
   
E3LBE0_PUCGT
TubercuList»
0.0
PGTG_19762 PQ-loop repeat-containing protein 1 Puccinia graminis
TI:5297 None
 
H6QPP7_PUCGT
TubercuList»
0.0
PGTG_20801 PQ-loop repeat-containing protein 1 Puccinia graminis
TI:5297 None
 
S66A2_RAT
RGD»
1.0
Slc66a2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Rattus norvegicus
TI:10116 None
 
ANY1_YEAST
SGD»
5.8
ANY1 Scramblase ANY1 (Antagonizes NEO1 phospholipid
flippase protein 1) (CDC50 suppressor 1)		 Saccharomyces cerevisiae
TI:4932 None
 
A7E934_SCLS1
TubercuList»
0.0
SS1G_01814 PQ loop repeat protein Sclerotinia sclerotiorum
TI:5180 None
 
A0A7M7N4G6_STRPU
EnsemblMetazoa»
0.0
Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7N4T5_STRPU
EnsemblMetazoa»
0.0
Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A287BEV0_PIG
Ensembl»
0.0
SLC66A2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Sus scrofa
TI:9823 None
   
B8C010_THAPS
euHCVdb»
0.0
THAPSDRAFT_4691 Uncharacterized protein Thalassiosira pseudonana
TI:35128 None
 
D6WL54_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_14297 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Tribolium castaneum
TI:7070 None
 
A2DHR3_TRIV3
TubercuList»
0.0
TVAG_366190 PQ loop repeat family protein Trichomonas vaginalis
TI:5722 None
 
A2DVV9_TRIV3
TubercuList»
0.0
TVAG_252170 PQ loop repeat family protein Trichomonas vaginalis
TI:5722 None
 
A2F4E6_TRIV3
TubercuList»
0.0
TVAG_257650 PQ loop repeat family protein Trichomonas vaginalis
TI:5722 None
 
A2FVP7_TRIV3
TubercuList»
0.0
TVAG_264950 PQ loop repeat family protein Trichomonas vaginalis
TI:5722 None
 
B3RVL0_TRIAD
CTD»
0.0
TRIADDRAFT_23940 PQ-loop repeat-containing protein 1 Trichoplax adhaerens
TI:10228 None
 
Q38FT6_TRYB2
TubercuList»
0.0
Tb09.160.1010 PQ loop repeat protein Trypanosoma brucei
TI:5691 None
 
A0A1L8FY83_XENLA
CTD»
0.0
slc66a2.1.L Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Xenopus laevis
TI:8355 None
   
A0A1L8GKX6_XENLA
Xenbase»
0.0
slc66a2.2.L Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Xenopus laevis
TI:8355 None
   
A0A8J0T6Q1_XENLA
Xenbase»
0.0
slc66a2.S Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Xenopus laevis
TI:8355 None
   
A4IGL5_XENTR
Xenbase»
0.0
slc66a2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Xenopus tropicalis
TI:8364 None
 
Q08CY6_XENTR
Xenbase»
0.0
slc66a2.2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Xenopus tropicalis
TI:8364 None
 
S66A2_XENLA
Xenbase»
0.0
slc66a2 Solute carrier family 66 member
2 (PQ-loop repeat-containing protein 1)		 Xenopus laevis
TI:8355 None
 
Q6C4S3_YARLI
TubercuList»
0.0
YALI0_E24145g YALI0E24145p Yarrowia lipolytica
TI:4952 None