Collated Gene Ontology terms

Biological process: nucleotide binding(2023) D-xylose 1-dehydrogenase (NADP+) activity(2004, 2015, 2017, 2022, 2023) oxidoreductase activity(2023) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(2023) glucose-fructose oxidoreductase activity(2023) inositol 2-dehydrogenase activity(2023)

Molecular function: D-xylose catabolic process2004, 2015, 2017, 2022, 2023 translation2021 regulation of apoptotic process2023 intracellular signal transduction2023 extrinsic apoptotic signaling pathway2023 DNA damage response2023

Cellular component: nucleus2009, 2023 cytosol2009, 2023 mitochondrion2023 cytoplasm2023

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 10/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 6/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
DHDH_MOUSE
Ensembl»
2.6
Dhdh Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase)
(D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase)		 Mus musculus
TI:10090 None
 
D4A903_RAT
RGD»
2.0
Dhdh Dihydrodiol dehydrogenase Rattus norvegicus
TI:10116 None
   
DHDH_HUMAN
Ensembl»
1.0
DHDH Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase) (D-xylose-NADP
dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase) (Hum2DD)		 Homo sapiens
TI:9606 None
 
M9PE54_DROME
FlyBase»
1.0
BVRA Uncharacterized protein, isoform
B (EC 1.1.1.179)		 Drosophila melanogaster
TI:7227 None
 
Q9VJH7_DROME
FlyBase»
1.0
Dmel\CG13280 Uncharacterized protein, isoform
A (EC 1.1.1.179)		 Drosophila melanogaster
TI:7227 None
 
Q9VQB4_DROME
FlyBase»
1.0
Dmel\CG3609 LD06553p (Uncharacterized protein, isoform A (EC 1.1.1.179))
(Uncharacterized protein, isoform B) (Uncharacterized protein, isoform C)		 Drosophila melanogaster
TI:7227 None
 
XDH_SCHPO
PomBase»
1.0
dhd1 Probable D-xylose 1-dehydrogenase (NADP(+)) (XDH) (EC 1.1.1.179) (D-xylose-NADP
dehydrogenase) (Dimeric dihydrodiol dehydrogenase homolog) (NADP(+)-dependent D-xylose dehydrogenase)		 Schizosaccharomyces pombe
TI:4896 None
 
A0A0D1DWH1_USTMA
EnsemblFungi»
0.0
UMAG_10732 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Ustilago maydis
TI:5270 None
 
A0A0D1E8W8_USTMA
EnsemblFungi»
0.0
UMAG_01988 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Ustilago maydis
TI:5270 None
 
A0A1B0GSH8_MOUSE
Ensembl»
0.0
Gm45808 Predicted gene 45808 Mus musculus
TI:10090 None
   
A0A1D5Q3I5_MACMU
Ensembl»
0.0
DHDH Dihydrodiol dehydrogenase Macaca mulatta
TI:9544 None
   
A0A1S4H0I5_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A0A2I3T8Z2_PANTR
Ensembl»
0.0
DHDH Dihydrodiol dehydrogenase Pan troglodytes
TI:9598 None
 
A0A2K3E4U2_CHLRE
EnsemblPlants»
0.0
CHLRE_01g003200v5 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None
 
A0A337S785_FELCA
Ensembl»
0.0
DHDH Dihydrodiol dehydrogenase Felis catus
TI:9685 None
 
A0A7M7HHT9_STRPU
EnsemblMetazoa»
0.0
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7NZ06_STRPU
EnsemblMetazoa»
0.0
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7NZH0_STRPU
EnsemblMetazoa»
0.0
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7NZI8_STRPU
EnsemblMetazoa»
0.0
Dimeric dihydrodiol dehydrogenase Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7TGY3_STRPU
EnsemblMetazoa»
0.0
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Strongylocentrotus purpuratus
TI:7668 None
   
A0A803T9K0_ANOCA
Ensembl»
0.0
LOC100560929 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Anolis carolinensis
TI:28377 None
   
A0A8V0XM79_CHICK
Ensembl»
0.0
DHDH Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Gallus gallus
TI:9031 None
   
A0A9J7KHJ2_BRAFL
CTD»
0.0
LOC118407083 Uncharacterized protein LOC118407083 Branchiostoma floridae
TI:7739 None
   
A0A9J7LKF6_BRAFL
CTD»
0.0
LOC118420636 Trans-1,2-dihydrobenzene-1,2-diol
dehydrogenase-like		 Branchiostoma floridae
TI:7739 None 		     
A7E983_SCLS1
EnsemblFungi»
0.0
SS1G_01863 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None
 
A7SPL2_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g172894 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Nematostella vectensis
TI:45351 None
 
A9WGQ5_CHLAA
EnsemblBacteria»
0.0
Caur_3022 Oxidoreductase domain protein Chloroflexus aurantiacus
TI:1108 None
 
B7PJ28_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW024220 Dimeric dihydrodiol dehydrogenase, putative Ixodes scapularis
TI:6945 None 		 
   
B7Q030_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW009997 Dimeric dihydrodiol dehydrogenase,
putative (EC 1.1.1.18)		 Ixodes scapularis
TI:6945 None
 
B8C673_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_23184 Dihydrodiol dehydrogenase (EC 1.3.1.20) Thalassiosira pseudonana
TI:35128 None
 
B8CGN5_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_25901 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
B8LBT4_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_36572 Dimeric dihydrodiol dehydrogenase Thalassiosira pseudonana
TI:35128 None
 
B8LCK0_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_269868 Oxidoreductase Thalassiosira pseudonana
TI:35128 None
 
B9TAW4_RICCO
EnsemblBacteria»
0.0
RCOM_0000790 Oxidoreductase, putative (EC 1.1.99.28) Ricinus communis
TI:3988 None
 
B9TGK5_RICCO
EnsemblBacteria»
0.0
RCOM_1797010 Oxidoreductase, putative (EC 1.1.99.28) Ricinus communis
TI:3988 None
 
B9TMQ7_RICCO
EnsemblBacteria»
0.0
RCOM_2113480 Oxidoreductase, putative (EC 1.1.99.28) Ricinus communis
TI:3988 None
 
D6W762_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_14228 Trans-1,2-dihydrobenzene-1,2-diol
dehydrogenase-like Protein		 Tribolium castaneum
TI:7070 None
 
D6W763_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_14229 Trans-1,2-dihydrobenzene-1,2-diol
dehydrogenase-like Protein		 Tribolium castaneum
TI:7070 None
 
D6W764_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_14230 Trans-1,2-dihydrobenzene-1,2-diol
dehydrogenase-like Protein		 Tribolium castaneum
TI:7070 None 		 
   
D6W765_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_14231 Trans-1,2-dihydrobenzene-1,2-diol
dehydrogenase-like Protein		 Tribolium castaneum
TI:7070 None 		 
   
DHDH_BOVIN
Ensembl»
0.0
DHDH Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase)
(D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase)		 Bos taurus
TI:9913 None
 
DHDH_CANLF
Ensembl»
0.0
DHDH Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (Can2DD) (D-xylose 1-dehydrogenase)
(D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase)		 Canis lupus
TI:9612 None
 
DHDH_DANRE
ZFIN»
0.0
dhdh Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase)
(D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase)		 Danio rerio
TI:7955 None
 
DHDH_PIG
Ensembl»
0.0
DHDH Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase) (D-xylose-NADP
dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase) (Sus2DD)		 Sus scrofa
TI:9823 None
 
DHDH_XENTR
Xenbase»
0.0
dhdh Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase)
(D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase)		 Xenopus tropicalis
TI:8364 None
 
E3KW78_PUCGT
EnsemblFungi»
0.0
PGTG_14758 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Puccinia graminis
TI:5297 None
 
E3L8H1_PUCGT
EnsemblFungi»
0.0
PGTG_18910 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Puccinia graminis
TI:5297 None
 
F6XRN3_MONDO
Ensembl»
0.0
Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Monodelphis domestica
TI:13616 None 		     
F6Y011_CIOIN
Ensembl»
0.0
LOC100186038 Trans-1,2-dihydrobenzene-1,2-diol
dehydrogenase-like		 Ciona intestinalis
TI:7719 None
 
F7C081_HORSE
Ensembl»
0.0
DHDH Dihydrodiol dehydrogenase Equus caballus
TI:9796 None
   
G3QFV4_GORGO
Ensembl»
0.0
DHDH Dihydrodiol dehydrogenase Gorilla gorilla
TI:9593 None
 
H2MDA8_ORYLA
Ensembl»
0.0
LOC101170260 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Oryzias latipes
TI:8090 None
   
H2MDB6_ORYLA
Ensembl»
0.0
LOC101161387 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Oryzias latipes
TI:8090 None
   
H3G9U2_PHYRM
EnsemblProtists»
0.0
Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
H3GUI7_PHYRM
EnsemblProtists»
0.0
Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
H3GUI8_PHYRM
EnsemblProtists»
0.0
Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
H9GP63_ANOCA
Ensembl»
0.0
LOC100561324 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Anolis carolinensis
TI:28377 None
   
H9GP73_ANOCA
Ensembl»
0.0
LOC100560732 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Anolis carolinensis
TI:28377 None
   
H9GS25_ANOCA
Ensembl»
0.0
Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Anolis carolinensis
TI:28377 None
   
O06789_MYCTU
TubercuList»
0.0
Rv1752 Oxidoreductase Mycobacterium tuberculosis
TI:1773 None 		 
   
Q0UWG4_PHANO
EnsemblFungi»
0.0
SNOG_03900 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
Q0UY29_PHANO
EnsemblFungi»
0.0
SNOG_03335 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
Q0V5D7_PHANO
EnsemblFungi»
0.0
SNOG_00777 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
Q1K5G9_NEUCR
EnsemblFungi»
0.0
NCU01704 NADP:D-xylose dehydrogenase Neurospora crassa
TI:5141 None
 
Q4WCC9_ASPFU
EnsemblFungi»
0.0
AFUA_8G04870 NAD binding Rossmann fold
oxidoreductase, putative (EC 1.-.-.-)		 Aspergillus fumigatus
TI:746128 None
 
Q4WJ22_ASPFU
EnsemblFungi»
0.0
AFUA_1G07520 Dimeric dihydrodiol dehydrogenase,
putative (EC 1.-.-.-)		 Aspergillus fumigatus
TI:746128 None
 
Q5AD31_CANAL
EnsemblFungi»
0.0
CAALFM_C200880WA orf19.9584 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Candida albicans
TI:5476 None
 
Q5AST8_EMENI
EnsemblFungi»
0.0
ANIA_08642 NAD binding Rossmann fold
oxidoreductase, putative (AFU_orthologue AFUA_8G04870)		 Emericella nidulans
TI:162425 None
 
Q5B2V7_EMENI
EnsemblFungi»
0.0
ANIA_05123 Dimeric dihydrodiol dehydrogenase,
putative (AFU_orthologue AFUA_1G07520)		 Emericella nidulans
TI:162425 None
 
Q5B7F6_EMENI
EnsemblFungi»
0.0
ANIA_03524 NAD binding Rossmann fold
oxidoreductase, putative (AFU_orthologue AFUA_8G04870)		 Emericella nidulans
TI:162425 None
 
Q5BHE4_EMENI
EnsemblFungi»
0.0
ANIA_00036 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Emericella nidulans
TI:162425 None
 
Q5KA13_CRYNJ
EnsemblFungi»
0.0
CNJ03430 Uncharacterized protein Cryptococcus neoformans
TI:5207 None 		 
   
Q5KD24_CRYNJ
EnsemblFungi»
0.0
CNH03050 Uncharacterized protein Cryptococcus neoformans
TI:5207 None 		 
   
Q5KEM9_CRYNJ
EnsemblFungi»
0.0
CNF04900 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Cryptococcus neoformans
TI:5207 None
 
Q5KFZ8_CRYNJ
EnsemblFungi»
0.0
CNF00010 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Cryptococcus neoformans
TI:5207 None
 
Q5KG53_CRYNJ
EnsemblFungi»
0.0
CNE04820 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Cryptococcus neoformans
TI:5207 None
 
Q5KLC1_CRYNJ
EnsemblFungi»
0.0
CNC00020 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Cryptococcus neoformans
TI:5207 None
 
Q7Q164_ANOGA
EnsemblMetazoa»
0.0
1279361 AGAP009945-PA Anopheles gambiae
TI:7165 None
 
Q7T379_DANRE
ZFIN»
0.0
dhdhl Dhdhl protein (Dihydrodiol
dehydrogenase (Dimeric), like)		 Danio rerio
TI:7955 None
 
Q8P933_XANCP
EnsemblBacteria»
0.0
XCC2033 Oxidoreductase Xanthomonas campestris
TI:339 None
 
Q8PCB9_XANCP
EnsemblBacteria»
0.0
gfo Glucose-fructose oxidoreductase Xanthomonas campestris
TI:339 None
 
Q8YA82_LISMO
EnsemblBacteria»
0.0
lmo0277 Lmo0277 protein Listeria monocytogenes
TI:1639 None
 
Q9RKP3_STRCO
EnsemblBacteria»
0.0
SCO2285 Oxidoreductase Streptomyces coelicolor
TI:1902 None
 
Q9RW70_DEIRA
EnsemblBacteria»
0.0
DR_0799 Glucose-fructose oxidoreductase Deinococcus radiodurans
TI:1299 None
 
T1G1W7_HELRO
EnsemblMetazoa»
0.0
20215065 Gfo/Idh/MocA-like oxidoreductase
N-terminal domain-containing protein		 Helobdella robusta
TI:6412 None
 
W5NDA8_LEPOC
Ensembl»
0.0
DHDH Dihydrodiol dehydrogenase Lepisosteus oculatus
TI:7918 None