Collated Gene Ontology terms

Biological process: nucleotide binding(2025) kinase activity(2025) transferase activity(2025) protein serine/threonine kinase activity(2025) ATP binding(2025) GTP binding(2025) cysteine-type endopeptidase activity(2025) death receptor binding(2022) caspase binding(2022) RNA binding(2003)

Molecular function: regulation of apoptotic process2025 signal transduction2025 proteolysis2025 positive regulation of innate immune response2023 extrinsic apoptotic signaling pathway2022

Cellular component: nucleoplasm2017, 2024, 2025 nucleolus2003, 2025 cytosol2025 CD95 death-inducing signaling complex2022

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
H9GE15_ANOCA
Ensembl»
0.0
NOL4L Nucleolar protein 4 like Anolis carolinensis
TI:28377 None
   
H9GPU8_ANOCA
Ensembl»
0.0
NOL4 Nucleolar protein 4 Anolis carolinensis
TI:28377 None
   
A0A1S4GXI6_ANOGA
EnsemblMetazoa»
0.0
Nucleolar protein 4
helical domain-containing protein		 Anopheles gambiae
TI:7165 None 		 
 
A0A1S4GXJ5_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None 		 
 
A0ABI0NVE2_BOVIN
Ensembl»
0.0
NOL4L Nucleolar protein 4 like Bos taurus
TI:9913 None 		     
G3N0K6_BOVIN
Ensembl»
0.0
NOL4 Nucleolar protein 4 Bos taurus
TI:9913 None
   
A0A9J7HDW4_BRAFL
euHCVdb»
0.0
LOC118403288 Uncharacterized protein LOC118403288 Branchiostoma floridae
TI:7739 None 		     
A0A9J7HGW6_BRAFL
neXtProt»
0.0
LOC118403534 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7HH58_BRAFL
neXtProt»
0.0
LOC118403530 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7HTA9_BRAFL
neXtProt»
0.0
LOC118407683 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7HTQ3_BRAFL
euHCVdb»
0.0
LOC118408947 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7HVE8_BRAFL
euHCVdb»
0.0
LOC118407687 Death-associated protein kinase dapk-1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7HW40_BRAFL
euHCVdb»
0.0
LOC118408995 Uncharacterized protein LOC118408995 Branchiostoma floridae
TI:7739 None
   
A0A9J7HW84_BRAFL
neXtProt»
0.0
LOC118408943 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7KBD2_BRAFL
neXtProt»
0.0
LOC118407594 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7KBG8_BRAFL
neXtProt»
0.0
LOC118407691 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7KCU4_BRAFL
neXtProt»
0.0
LOC118408944 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7KFJ8_BRAFL
neXtProt»
0.0
LOC118403277 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7KGL6_BRAFL
euHCVdb»
0.0
LOC118403276 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7KHW1_BRAFL
euHCVdb»
0.0
LOC118407689 Uncharacterized protein LOC118407689 Branchiostoma floridae
TI:7739 None
   
A0A9J7KJC9_BRAFL
neXtProt»
0.0
LOC118406355 Protein TORNADO 1-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7KKV5_BRAFL
neXtProt»
0.0
LOC118407684 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7KL91_BRAFL
euHCVdb»
0.0
LOC118408946 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7KNA6_BRAFL
euHCVdb»
0.0
LOC118409888 Ankyrin repeat and
KH domain-containing protein CBG24701-like		 Branchiostoma floridae
TI:7739 None 		     
A0A9J7KP77_BRAFL
euHCVdb»
0.0
LOC118410195 Nucleolar protein 4-like isoform X1 Branchiostoma floridae
TI:7739 None 		     
A0A9J7KPB8_BRAFL
euHCVdb»
0.0
LOC118410191 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7L765_BRAFL
neXtProt»
0.0
LOC118416324 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7L799_BRAFL
neXtProt»
0.0
LOC118416378 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7L7G6_BRAFL
neXtProt»
0.0
LOC118416377 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7L809_BRAFL
neXtProt»
0.0
LOC118416371 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7L8I6_BRAFL
euHCVdb»
0.0
LOC118416325 Death-associated protein kinase dapk-1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7L8V7_BRAFL
neXtProt»
0.0
LOC118416123 Death-associated protein kinase
1-like isoform X1		 Branchiostoma floridae
TI:7739 None
   
A0A9J7L994_BRAFL
euHCVdb»
0.0
LOC118416320 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7L9I3_BRAFL
neXtProt»
0.0
LOC118417311 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7L9U3_BRAFL
euHCVdb»
0.0
LOC118417266 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7L9Z7_BRAFL
euHCVdb»
0.0
LOC118417313 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7LA20_BRAFL
neXtProt»
0.0
LOC118417375 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7LBE2_BRAFL
euHCVdb»
0.0
LOC118417377 Uncharacterized protein LOC118417377 Branchiostoma floridae
TI:7739 None
   
A0A9J7LBW4_BRAFL
neXtProt»
0.0
LOC118417310 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7LCX3_BRAFL
euHCVdb»
0.0
LOC118418686 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7M0K5_BRAFL
euHCVdb»
0.0
LOC118427062 Protein VAPYRIN-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7M1T3_BRAFL
neXtProt»
0.0
LOC118427058 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7M3S1_BRAFL
euHCVdb»
0.0
LOC118427059 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7MAX7_BRAFL
euHCVdb»
0.0
LOC118430777 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7MR27_BRAFL
euHCVdb»
0.0
LOC118416596 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7MSA1_BRAFL
euHCVdb»
0.0
LOC118416372 Death-associated protein kinase dapk-1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7MSW7_BRAFL
neXtProt»
0.0
LOC118416597 Uncharacterized protein LOC118416597 Branchiostoma floridae
TI:7739 None
   
A0A9J7MTS9_BRAFL
neXtProt»
0.0
LOC118417369 Death-associated protein kinase dapk-1-like Branchiostoma floridae
TI:7739 None
   
A0A9J7N064_BRAFL
euHCVdb»
0.0
LOC118421897 Death-associated protein kinase 1-like Branchiostoma floridae
TI:7739 None 		     
A0A8I3PLG0_CANLF
Ensembl»
0.0
NOL4L Nucleolar protein 4 like Canis lupus
TI:9612 None
   
A0A8I3RW58_CANLF
Ensembl»
0.0
NOL4 Nucleolar protein 4 Canis lupus
TI:9612 None
   
A0AB13ABJ9_DANRE
ZFIN»
0.0
nol4lb Nucleolar protein 4-like b isoform 2 Danio rerio
TI:7955 None 		     
F1QGF6_DANRE
ZFIN»
0.0
nol4la Nucleolar protein 4-like a
(Nucleolar protein 4-like isoform X1)		 Danio rerio
TI:7955 None 		 
 
E9GAX8_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_100633 Nucleolar protein 4
helical domain-containing protein		 Daphnia pulex
TI:6669 None 		 
 
A0A1W5PXH3_DROME
FlyBase»
0.0
CG17341 Uncharacterized protein, isoform E Drosophila melanogaster
TI:7227 None
 
A0A9L0SUK9_HORSE
Ensembl»
0.0
NOL4L Nucleolar protein 4 like Equus caballus
TI:9796 None
   
A0A9L0SXB7_HORSE
Ensembl»
0.0
NOL4 Nucleolar protein 4 Equus caballus
TI:9796 None
   
A0ABI7XAK6_FELCA
Ensembl»
0.0
NOL4 Nucleolar protein 4
helical domain-containing protein		 Felis catus
TI:9685 None 		     
A0ABI7ZGJ9_FELCA
Ensembl»
0.0
NOL4L Nucleolar protein 4
helical domain-containing protein		 Felis catus
TI:9685 None 		     
A0A1D5P4K7_CHICK
Ensembl»
0.0
NOL4L Nucleolar protein 4 like Gallus gallus
TI:9031 None
   
A0A8V0XMV7_CHICK
Ensembl»
0.0
NOL4 Nucleolar protein 4 like Gallus gallus
TI:9031 None
   
A0A2I2Y1U8_GORGO
Ensembl»
0.0
NOL4 Nucleolar protein 4 Gorilla gorilla
TI:9593 None
 
G3QIN7_GORGO
Ensembl»
0.0
NOL4L Nucleolar protein 4 like Gorilla gorilla
TI:9593 None
 
T1ET06_HELRO
EnsemblMetazoa»
0.0
20199706 Death domain-containing protein Helobdella robusta
TI:6412 None
 
T1EXL4_HELRO
EnsemblMetazoa»
0.0
20201314 Nucleolar protein 4
helical domain-containing protein		 Helobdella robusta
TI:6412 None 		 
 
NOL4L_HUMAN
Ensembl»
0.0
NOL4L Nucleolar protein 4-like Homo sapiens
TI:9606 None
 
NOL4_HUMAN
Ensembl»
0.9
NOL4 Nucleolar protein
4 (Nucleolar-localized protein)		 Homo sapiens
TI:9606 None
 
B7Q8I6_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW010756 Nucleolar protein 4
helical domain-containing protein		 Ixodes scapularis
TI:6945 None 		 
 
W5MEY8_LEPOC
Ensembl»
0.0
Nucleolar protein 4-like b Lepisosteus oculatus
TI:7918 None 		 
 
W5MGF5_LEPOC
Ensembl»
0.0
Nucleolar protein 4 Lepisosteus oculatus
TI:7918 None 		 
 
F7CJM9_MACMU
Ensembl»
0.0
NOL4L Nucleolar protein 4 like Macaca mulatta
TI:9544 None
   
G7NKK8_MACMU
Ensembl»
0.0
NOL4 Nucleolar protein 4 Macaca mulatta
TI:9544 None
 
F6RXF1_MONDO
Ensembl»
0.0
NOL4L Nucleolar protein 4 like Monodelphis domestica
TI:13616 None
   
F7FK61_MONDO
Ensembl»
0.0
NOL4 Nucleolar protein 4 Monodelphis domestica
TI:13616 None 		     
NOL4L_MOUSE
AG»
0.0
Nol4l Nucleolar protein 4-like Mus musculus
TI:10090 None
 
NOL4_MOUSE
Ensembl»
0.0
Nol4 Nucleolar protein 4 Mus musculus
TI:10090 None
 
A0A6I8NXM6_ORNAN
Ensembl»
0.0
NOL4 Nucleolar protein 4 Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8PFD0_ORNAN
Ensembl»
0.0
NOL4L Nucleolar protein 4 like Ornithorhynchus anatinus
TI:9258 None
   
H2MIK3_ORYLA
Ensembl»
0.0
nol4la Nucleolar protein 4-like a Oryzias latipes
TI:8090 None 		     
H2N145_ORYLA
Ensembl»
0.0
NOL4L Nucleolar protein 4-like b Oryzias latipes
TI:8090 None 		     
H2QEF4_PANTR
Ensembl»
0.0
NOL4 Nucleolar protein 4 Pan troglodytes
TI:9598 None
 
H2R925_PANTR
Ensembl»
0.0
NOL4L Nucleolar protein 4 like Pan troglodytes
TI:9598 None
 
A0ABK0LMK3_RAT
RGD»
0.0
Nol4l Nucleolar protein 4-like Rattus norvegicus
TI:10116 None
   
D4A3P4_RAT
RGD»
0.0
Nol4 Nucleolar protein 4 Rattus norvegicus
TI:10116 None
   
A0A7M7NMP7_STRPU
EnsemblMetazoa»
0.0
Nucleolar protein 4
helical domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A7M7NPR5_STRPU
EnsemblMetazoa»
0.0
Nucleolar protein 4
helical domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A7M7SXX4_STRPU
EnsemblMetazoa»
0.0
Nucleolar protein 4 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A286ZWH8_PIG
Ensembl»
0.0
NOL4L Nucleolar protein 4 like
(Nucleolar protein 4-like isoform 1)		 Sus scrofa
TI:9823 None
 
F1SAK1_PIG
Ensembl»
0.0
NOL4 Nucleolar protein 4 Sus scrofa
TI:9823 None
 
A0A139WES5_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_31212 Nucleolar protein 4-like Protein Tribolium castaneum
TI:7070 None 		 
 
D6WVZ0_TRICA
CTD»
0.0
AUGUSTUS-3.0.2_06299 Death-associated protein
kinase dapk-1-like Protein		 Tribolium castaneum
TI:7070 None
 
B3S622_TRIAD
CTD»
0.0
TRIADDRAFT_64193 CARD domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B3SAX5_TRIAD
CTD»
0.0
TRIADDRAFT_61414 COR domain-containing protein Trichoplax adhaerens
TI:10228 None 		 
 
B3SBR8_TRIAD
CTD»
0.0
TRIADDRAFT_61712 COR domain-containing protein Trichoplax adhaerens
TI:10228 None 		 
 
B3SDK8_TRIAD
CTD»
0.0
TRIADDRAFT_62367 Death domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B3SE94_TRIAD
CTD»
0.0
TRIADDRAFT_62591 COR domain-containing protein Trichoplax adhaerens
TI:10228 None 		 
 
A0A1L8ERI7_XENLA
Xenbase»
0.0
nol4l.L Nucleolar protein 4-like L homeolog isoform X1 Xenopus laevis
TI:8355 None 		     
A0A1L8FYW1_XENLA
Xenbase»
0.0
nol4.L Nucleolar protein 4 isoform X1 Xenopus laevis
TI:8355 None 		     
A0A8J0T6V8_XENLA
Xenbase»
0.0
nol4.S Nucleolar protein 4 Xenopus laevis
TI:8355 None 		     
A0A8J0TYH2_XENLA
Xenbase»
0.0
nol4l.S Nucleolar protein 4-like isoform X1 Xenopus laevis
TI:8355 None 		     
A0A8J1JPI0_XENTR
Xenbase»
0.0
nol4 Nucleolar protein 4 isoform X1 Xenopus tropicalis
TI:8364 None 		     
F6UTC7_XENTR
Xenbase»
0.0
nol4l Nucleolar protein 4-like Xenopus tropicalis
TI:8364 None