Standard knownness: 5.8; Custom knownness: None; Num. species: 39; Orthology database: Panther19.0; Protein members: 45
Molecular function: snRNA 3'-end processing2012, 2019, 2025 RNA polymerase II transcription initiation surveillance2025 snRNA processing2006, 2012, 2025 protein localization to chromatin2025 regulation of transcription elongation by RNA polymerase II2025 positive regulation of neuron differentiation2019 positive regulation of gene expression2019 negative regulation of BMP signaling pathway2023
Cellular component: integrator complex2006, 2012, 2024, 2025 nucleus2024, 2025 chromosome2025 INTAC complex2025 chromatin2025 nucleoplasm2015 cytosol2023
| Chordates: | 22/21 | ![]() |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 4/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 0/4 | |
| Harosa: | 1/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 3/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
Click here to switch to the previous version of the database.
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
A0A1S4H7K5_ANOGA EnsemblMetazoa» |
|
|
INTS8 TPR repeats domain-containing protein |
Anopheles gambiae TI:7165 None |
|
|
|
||||||
|
A0A7M7LTG6_STRPU EnsemblMetazoa» |
|
|
INTS8 TPR repeats domain-containing protein |
Strongylocentrotus purpuratus TI:7668 None |
|
|
|||||||
|
F7AP73_CIOIN Ensembl» |
|
|
Integrator complex subunit 8 |
Ciona intestinalis TI:7719 None |
|
|
|
||||||
|
H3GGI9_PHYRM EnsemblProtists» |
|
|
INTS8 TPR repeats domain-containing protein |
Phytophthora ramorum TI:164328 None |
|
|
|
||||||
|
W5MH81_LEPOC Ensembl» |
|
|
Integrator complex subunit 8 |
Lepisosteus oculatus TI:7918 None |
|
|
|
||||||
|
T1F3J1_HELRO EnsemblMetazoa» |
|
|
20203390 | INTS8 TPR repeats domain-containing protein |
Helobdella robusta TI:6412 None |
|
|
|
|||||
|
T1G2Q8_HELRO EnsemblMetazoa» |
|
|
20215356 | INTS8 TPR repeats domain-containing protein |
Helobdella robusta TI:6412 None |
|
|
|
|||||
|
D6WSC4_TRICA euHCVdb» |
|
|
AUGUSTUS-3.0.2_09538 | Integrator complex subunit 8-like Protein |
Tribolium castaneum TI:7070 None |
|
|
|
|||||
|
Q54VK4_DICDI dictyBase» |
|
|
DDB_G0280283 | Uncharacterized protein |
Dictyostelium discoideum TI:44689 None |
|
|
|
|||||
|
INT8_DICDI dictyBase» |
|
|
DDB_G0280285 | Integrator complex subunit 8-like protein |
Dictyostelium discoideum TI:44689 None |
|
|
|
|||||
|
F0ZZR3_DICPU TubercuList» |
|
|
DICPUDRAFT_95711 | INTS8 TPR repeats domain-containing protein |
Dictyostelium purpureum TI:5786 None |
|
|
|
|||||
|
A0A1D5P482_CHICK Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Gallus gallus TI:9031 None |
|
|
||||||
|
A0A5F5Q074_HORSE Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Equus caballus TI:9796 None |
|
|
||||||
|
A0A803TYN8_ANOCA Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Anolis carolinensis TI:28377 None |
|
|
||||||
|
A0A8I3NNC6_CANLF Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Canis lupus TI:9612 None |
|
|
||||||
|
A0ABI7ZU49_FELCA Ensembl» |
|
|
INTS8 | INTS8 TPR repeats domain-containing protein |
Felis catus TI:9685 None |
|
|
||||||
|
A5PJS8_BOVIN Ensembl» |
|
|
INTS8 | INTS8 protein (Integrator complex subunit 8) |
Bos taurus TI:9913 None |
|
|
|
|||||
|
F1RY55_PIG Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Sus scrofa TI:9823 None |
|
|
||||||
|
F6Q8M0_MONDO Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Monodelphis domestica TI:13616 None |
|
|
||||||
|
F6UJJ6_ORNAN Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Ornithorhynchus anatinus TI:9258 None |
|
|
||||||
|
F7GDZ1_MACMU Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Macaca mulatta TI:9544 None |
|
|
||||||
|
G3QRQ7_GORGO Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Gorilla gorilla TI:9593 None |
|
|
|
|||||
|
H2LUR6_ORYLA Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Oryzias latipes TI:8090 None |
|
|
||||||
|
INT8_HUMAN Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 (Int8) (Protein kaonashi-1) |
Homo sapiens TI:9606 None |
|
|
|
|||||
|
K7DQK9_PANTR Ensembl» |
|
|
INTS8 | Integrator complex subunit 8 |
Pan troglodytes TI:9598 None |
|
|
|
|||||
|
INT8_DROME FlyBase» |
|
|
IntS8 | Integrator complex subunit 8 |
Drosophila melanogaster TI:7227 None |
|
|
|
|||||
|
D3ZLQ6_RAT RGD» |
|
|
Ints8 | Integrator complex subunit 8 |
Rattus norvegicus TI:10116 None |
|
|
||||||
|
INT8_MOUSE Ensembl» |
|
|
Ints8 | Integrator complex subunit 8 (Int8) |
Mus musculus TI:10090 None |
|
|
|
|||||
|
B7PXX0_IXOSC EnsemblMetazoa» |
|
|
IscW_ISCW020705 | INTS8 TPR repeats domain-containing protein |
Ixodes scapularis TI:6945 None |
|
|
|
|||||
|
F6SYI0_CIOIN Ensembl» |
|
|
LOC100179349 | Integrator complex subunit 8-like |
Ciona intestinalis TI:7719 None |
|
|
|
|||||
|
A0A7I4ETD2_PHYPA EnsemblPlants» |
|
|
LOC112290513 | INTS8 TPR repeats domain-containing protein |
Physcomitrium patens TI:3218 None |
|
|
|
|||||
|
C3ZBT2_BRAFL euHCVdb» |
|
|
LOC118418455 | Integrator complex subunit 8-like |
Branchiostoma floridae TI:7739 None |
|
|
|
|||||
|
A0A2R6XTQ6_MARPO euHCVdb» |
|
|
MARPO_0002s0011 | INTS8 TPR repeats domain-containing protein |
Marchantia polymorpha TI:3197 None |
|
|
|
|||||
|
A7STC9_NEMVE neXtProt» |
|
|
NEMVEDRAFT_v1g217194 | Integrator complex subunit 8 |
Nematostella vectensis TI:45351 None |
|
|
|
|||||
|
A7T669_NEMVE euHCVdb» |
|
|
NEMVEDRAFT_v1g222886 | INTS8 TPR repeats domain-containing protein |
Nematostella vectensis TI:45351 None |
|
|
|
|||||
|
D8S880_SELML euHCVdb» |
|
|
SELMODRAFT_111174 | INTS8 TPR repeats domain-containing protein |
Selaginella moellendorffii TI:88036 None |
|
|
|
|||||
|
D8S312_SELML euHCVdb» |
|
|
SELMODRAFT_443625 | F-box domain-containing protein |
Selaginella moellendorffii TI:88036 None |
|
|
|
|||||
|
B3RVA3_TRIAD CTD» |
|
|
TRIADDRAFT_23696 | INTS8 TPR repeats domain-containing protein |
Trichoplax adhaerens TI:10228 None |
|
|
|
|||||
|
A0A2A6BNP2_PRIPA EnsemblMetazoa» |
|
|
WBGene00100780 | INTS8 TPR repeats domain-containing protein |
Pristionchus pacificus TI:54126 None |
|
|
||||||
|
A8X5L3_CAEBR WormBase» |
|
|
ints-8 | Protein CBG08018 |
Caenorhabditis briggsae TI:6238 None |
|
|
|
|||||
|
H2KML7_CAEEL WormBase» |
|
|
ints-8 | INTegrator complex Subunit homolog |
Caenorhabditis elegans TI:6239 None |
|
|
|
|||||
|
A3KQN9_DANRE ZFIN» |
|
|
ints8 | Integrator complex subunit 8 |
Danio rerio TI:7955 None |
|
|
|
|||||
|
A4IH10_XENTR Xenbase» |
|
|
ints8 | Integrator complex subunit 8 (LOC100038299 protein) |
Xenopus tropicalis TI:8364 None |
|
|
|
|||||
|
INT8_XENLA Xenbase» |
|
|
ints8 | Integrator complex subunit 8 (Int8) |
Xenopus laevis TI:8355 None |
|
|
|
|||||
|
A0A8J1L0W2_XENLA CTD» |
|
|
ints8.S | Integrator complex subunit 8 isoform X1 |
Xenopus laevis TI:8355 None |
|
|
||||||