Collated Gene Ontology terms

Biological process: mechanosensitive monoatomic cation channel activity(2024, 2025) unfolded protein binding(2022)

Molecular function: regulation of autophagy2014, 2015, 2021, 2025 protein localization to plasma membrane2016, 2021, 2025 autophagy2025 photoreceptor cell maintenance2015, 2021, 2024, 2025 phosphatidylinositol phosphate biosynthetic process2016, 2025 visual perception2015, 2025 proprioception2017, 2025 cellular response to mechanical stimulus2017, 2025 monoatomic cation transmembrane transport2025 apoptotic process2025
negative regulation of phospholipid translocation2018, 2025 lipid metabolic process2025 cellular response to oxygen-glucose deprivation2024, 2025 vacuole organization2013, 2025 retina development in camera-type eye2024 defense response to bacterium2015 cell population proliferation2024 actin cytoskeleton organization2013, 2025 response to oxidative stress2025 response to heat2023 protein refolding2022 phloem or xylem histogenesis2024 mitophagy2025 mitochondrial fusion2025 mitochondrial fission2025

Cellular component: plasma membrane2013, 2016, 2017, 2021, 2024, 2025 endomembrane system2025 lysosome2009, 2013, 2015, 2021, 2025 cytoplasm2013, 2024, 2025 endosome membrane2025 cytoplasmic vesicle2025 autophagosome membrane2025 photoreceptor inner segment2015, 2025 apical plasma membrane2015, 2025 lysosomal membrane2016, 2025
Golgi apparatus2024, 2025 nucleus2023, 2025 cell periphery2018

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 12/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
DRAM2_HUMAN
Ensembl»
3.4
DRAM2 DNA damage-regulated autophagy modulator
protein 2 (Transmembrane protein 77)		 Homo sapiens
TI:9606 None
 
T150C_HUMAN
Ensembl»
1.5
TMEM150C Transmembrane protein 150C (Tentonin 3) Homo sapiens
TI:9606 None
 
DRAM1_HUMAN
Ensembl»
1.3
DRAM1 DNA damage-regulated autophagy modulator
protein 1 (Damage-regulated autophagy modulator)		 Homo sapiens
TI:9606 None
 
T150A_HUMAN
Ensembl»
2.1
TMEM150A Transmembrane protein 150A
(Transmembrane protein 150)		 Homo sapiens
TI:9606 None
 
T150C_MOUSE
Ensembl»
2.4
Tmem150c Transmembrane protein 150C (Tentonin 3) Mus musculus
TI:10090 None
 
DRAM2_MOUSE
Ensembl»
6.2
Dram2 DNA damage-regulated autophagy modulator
protein 2 (Transmembrane protein 77)		 Mus musculus
TI:10090 None
 
O77262_DROME
FlyBase»
0.5
anon-WO0140519.169 EG:22E5.9 protein (LP10820p) Drosophila melanogaster
TI:7227 None
 
SFK1_YEAST
SGD»
3.2
SFK1 Protein SFK1 (Suppressor of
four kinase protein 1)		 Saccharomyces cerevisiae
TI:4932 None
 
T150B_HUMAN
Ensembl»
0.0
TMEM150B Modulator of macroautophagy TMEM150B (Protein DRAM-3)
(Transmembrane protein 150B) (Transmembrane protein 224)		 Homo sapiens
TI:9606 None
 
T150C_RAT
RGD»
3.0
Tmem150c Transmembrane protein 150C Rattus norvegicus
TI:10116 None
 
DRAM1_MOUSE
Ensembl»
5.0
Dram1 DNA damage-regulated autophagy modulator
protein 1 (Damage-regulated autophagy modulator)		 Mus musculus
TI:10090 None
 
Q556P1_DICDI
dictyBase»
0.0
DDB_G0272881 DDB_G0274039 CWH43-like N-terminal domain-containing protein Dictyostelium discoideum
TI:44689 None
 
T150A_MOUSE
Ensembl»
2.5
Tmem150a Transmembrane protein 150A
(Transmembrane protein 150)		 Mus musculus
TI:10090 None
 
T150A_RAT
RGD»
2.5
Tmem150a Transmembrane protein 150A (Fasting-inducible integral
membrane protein TM6P1) (Transmembrane protein 150)		 Rattus norvegicus
TI:10116 None
 
T150B_MOUSE
Ensembl»
0.0
Tmem150b Modulator of macroautophagy
TMEM150B (Transmembrane protein 150B)		 Mus musculus
TI:10090 None
 
B5DEF4_RAT
RGD»
1.8
Dram1 DNA-damage regulated autophagy
modulator 1 (Dram protein)		 Rattus norvegicus
TI:10116 None
 
B8A6A2_DANRE
ZFIN»
0.5
si:dkey-228d14.5 Si:dkey-228d14.5 (Uncharacterized
protein LOC796266 precursor)		 Danio rerio
TI:7955 None
 
DRAM2_RAT
RGD»
4.5
Dram2 DNA damage-regulated autophagy modulator
protein 2 (Transmembrane protein 77)		 Rattus norvegicus
TI:10116 None
 
E9QGB9_DANRE
ZFIN»
0.0
zgc:154058 Transmembrane protein 150A-like
isoform 1 (Zgc:154058)		 Danio rerio
TI:7955 None
 
F1R7U0_DANRE
ZFIN»
1.0
dram2b DNA damage-regulated autophagy modulator protein 2b
isoform X1 (DNA-damage-regulated autophagy modulator 2b)		 Danio rerio
TI:7955 None
 
Q0P401_DANRE
ZFIN»
0.5
tmem150aa Transmembrane protein 150A
(Transmembrane protein 150)		 Danio rerio
TI:7955 None
 
Q23135_CAEEL
WormBase»
0.0
CELE_W03A5.2 W03A5.2 Transmembrane protein Caenorhabditis elegans
TI:6239 None
 
Q54KE7_DICDI
TubercuList»
0.0
DDB_G0287451 CWH43-like N-terminal domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q550K4_DICDI
TubercuList»
0.0
DDB_G0277073 CWH43-like N-terminal domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q559G4_DICDI
dictyBase»
0.0
DDB_G0272939 CWH43-like N-terminal domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q6IQJ3_DANRE
ZFIN»
0.0
zgc:86738 Transmembrane protein 150A-like (Zgc:86738) Danio rerio
TI:7955 None
 
Q7SXK4_DANRE
ZFIN»
0.5
tmem150ab Transmembrane protein 150A
(Transmembrane protein 150)		 Danio rerio
TI:7955 None
 
Q93319_CAEEL
WormBase»
0.0
C33A11.2 CELE_C33A11.2 Aa_trans domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q9U3J7_CAEEL
WormBase»
0.0
CELE_F11E6.6 F11E6.6 Transmembrane protein Caenorhabditis elegans
TI:6239 None
 
SFK1_SCHPO
PomBase»
0.0
sfk1 Protein sfk1 Schizosaccharomyces pombe
TI:4896 None
 
T150B_DANRE
ZFIN»
0.0
tmem150b Modulator of macroautophagy
TMEM150B (Transmembrane protein 150B)		 Danio rerio
TI:7955 None
 
A0A3Q2TW69_CHICK
Ensembl»
0.0
TMEM150C Transmembrane protein 150C Gallus gallus
TI:9031 None
   
A0A8M1PRT0_DANRE
ZFIN»
1.0
dram2a DNA damage-regulated autophagy
modulator protein 2		 Danio rerio
TI:7955 None
   
A0A8M9PS77_DANRE
ZFIN»
0.0
tmem150c Transmembrane protein 150C Danio rerio
TI:7955 None 		     
A0A8V0YD67_CHICK
Ensembl»
0.5
DRAM1 DNA damage regulated autophagy modulator 1 Gallus gallus
TI:9031 None
   
A0A8V1A1G7_CHICK
Ensembl»
0.0
DRAM2 DNA damage regulated autophagy modulator 2 Gallus gallus
TI:9031 None
   
A0AB32TIL2_DANRE
ZFIN»
3.2
dram1 DNA damage-regulated autophagy modulator
protein 1 isoform X1		 Danio rerio
TI:7955 None
   
D3ZEH7_RAT
RGD»
0.0
Tmem150b Transmembrane protein 150B Rattus norvegicus
TI:10116 None
   
E1C9H3_CHICK
Ensembl»
0.0
TMEM150B Transmembrane protein 150B Gallus gallus
TI:9031 None