Standard knownness: 4.5; Custom knownness: None; Num. species: 48; Orthology database: Panther19.0; Protein members: 200
                   Molecular function:
                   
                     regulation of autophagy2014, 2015, 2021, 2024
                   
                     protein localization to plasma membrane2016, 2021, 2024
                   
                     photoreceptor cell maintenance2015, 2021, 2024
                   
                     autophagy2024
                   
                     phosphatidylinositol phosphate biosynthetic process2016, 2024
                   
                     visual perception2015, 2024
                   
                     proprioception2017, 2024
                   
                     cellular response to mechanical stimulus2017, 2024
                   
                     retina development in camera-type eye2024
                   
                     monoatomic cation transmembrane transport2024
                   
                   
                      
                      
                      
                        
                          cell population proliferation2024
                        
                          apoptotic process2024
                        
                          phloem or xylem histogenesis2024
                        
                          negative regulation of phospholipid translocation2018, 2024
                        
                          catabolic process2005, 2024
                        
                          vacuole organization2013, 2024
                        
                          lipid metabolic process2024
                        
                          defense response to bacterium2015, 2021
                        
                          actin cytoskeleton organization2013, 2024
                        
                          monoatomic ion transmembrane transport2024
                        
                      
                    
                   
                   Cellular component:
                   
                     membrane2024
                   
                     plasma membrane2013, 2016, 2017, 2021, 2024
                   
                     lysosome2009, 2013, 2015, 2021, 2024
                   
                     endosome membrane2024
                   
                     endosome2024
                   
                     autophagosome membrane2024
                   
                     cytoplasm2013, 2024
                   
                     photoreceptor inner segment2015, 2024
                   
                     lysosomal membrane2016, 2024
                   
                     apical plasma membrane2015, 2024
                   
                   
                      
                      
                      
                        
                          intracellular membrane-bounded organelle2023, 2024
                        
                          Golgi apparatus2023, 2024
                        
                          cell periphery2018
                        
                      
                    
                    
| Chordates: | 22/21 |  | 
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 0/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 4/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 12/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 1/4 | |
| Harosa: | 1/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 | 
Click here to switch to the previous version of the database.
| UniProt ID Organism DB» | Standard knownness | clustom knownness | Gene name | Description | Species [Show all] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Q23135_CAEEL WormBase» | 
 | 
 | CELE_W03A5.2 W03A5.2 | Transmembrane protein | Caenorhabditis elegans TI:6239 None |  |  |  | |||||
| Q93319_CAEEL WormBase» | 
 | 
 | C33A11.2 CELE_C33A11.2 | DNA damage-regulated autophagy modulator protein 1 | Caenorhabditis elegans TI:6239 None |  |  |  | |||||
| Q9U3J7_CAEEL WormBase» | 
 | 
 | CELE_F11E6.6 F11E6.6 | Transmembrane protein | Caenorhabditis elegans TI:6239 None |  |  |  | |||||
| A0A2R8RK24_DANRE Ensembl» | 
 | 
 | tmem150c | Transmembrane protein 150C | Danio rerio TI:7955 None |  |  |  | |||||
| A0A8M1PRT0_DANRE CTD» | 
 | 
 | LOC792944 | DNA damage-regulated autophagy modulator protein 2 | Danio rerio TI:7955 None |  |  | ||||||
| B8A6A2_DANRE ZFIN» | 
 | 
 | si:dkey-228d14.5 | Si:dkey-228d14.5 (Transmembrane protein 150-like precursor) | Danio rerio TI:7955 None |  |  |  | |||||
| E9QGB9_DANRE ZFIN» | 
 | 
 | zgc:154058 | Uncharacterized protein LOC795538 isoform 1 (Zgc:154058) | Danio rerio TI:7955 None |  |  |  | |||||
| F1R7U0_DANRE ZFIN» | 
 | 
 | dram2 | DNA damage-regulated autophagy modulator protein 2 isoform X1 (DNA-damage-regulated autophagy modulator 2b) | Danio rerio TI:7955 None |  |  |  | |||||
| Q0P401_DANRE ZFIN» | 
 | 
 | tmem150 | Transmembrane protein 150 (Transmembrane protein 150Aa) | Danio rerio TI:7955 None |  |  |  | |||||
| Q5XJL0_DANRE ZFIN» | 
 | 
 | zgc:101811 | DNA damage-regulated autophagy modulator protein 1 (Zgc:101811) | Danio rerio TI:7955 None |  |  |  | |||||
| Q6IQJ3_DANRE ZFIN» | 
 | 
 | zgc:86738 | Uncharacterized protein LOC415231 (Zgc:86738) | Danio rerio TI:7955 None |  |  |  | |||||
| Q7SXK4_DANRE ZFIN» | 
 | 
 | tmem150ab | Transmembrane protein 150 (Zgc:66242) | Danio rerio TI:7955 None |  |  |  | |||||
| T150B_DANRE ZFIN» | 
 | 
 | tmem150b | Modulator of macroautophagy TMEM150B (Transmembrane protein 150B) | Danio rerio TI:7955 None |  |  |  | |||||
| Q54KE7_DICDI EnsemblProtists» | 
 | 
 | DDB_G0287451 | Frag1/DRAM/Sfk1 family protein | Dictyostelium discoideum TI:44689 None |  |  |  | |||||
| Q550K4_DICDI EnsemblProtists» | 
 | 
 | DDB_G0277073 | DUF998 domain-containing protein | Dictyostelium discoideum TI:44689 None |  |  |  | |||||
| Q556P1_DICDI dictyBase» | 
 | 
 | DDB_G0272881 DDB_G0274039 | Frag1/DRAM/Sfk1 family protein | Dictyostelium discoideum TI:44689 None |  |  |  | |||||
| Q559G4_DICDI dictyBase» | 
 | 
 | DDB_G0272939 | Frag1/DRAM/Sfk1 family protein | Dictyostelium discoideum TI:44689 None |  |  |  | |||||
| O77262_DROME FlyBase» | 
 | 
 | anon-WO0140519.169 | EG:22E5.9 protein (LP10820p) | Drosophila melanogaster TI:7227 None |  |  |  | |||||
| A0A8V0XBE0_CHICK Ensembl» | 
 | 
 | TMEM150C | Transmembrane protein 150C | Gallus gallus TI:9031 None |  |  | ||||||
| A0A8V0YD67_CHICK Ensembl» | 
 | 
 | DRAM1 | DNA damage regulated autophagy modulator 1 | Gallus gallus TI:9031 None |  |  | ||||||
| A0A8V1A6S1_CHICK Ensembl» | 
 | 
 | DRAM2 | DNA damage regulated autophagy modulator 2 | Gallus gallus TI:9031 None |  |  | ||||||
| E1C9H3_CHICK Ensembl» | 
 | 
 | TMEM150B | Uncharacterized protein | Gallus gallus TI:9031 None |  |  | ||||||
| DRAM1_HUMAN Ensembl» | 
 | 
 | DRAM1 | DNA damage-regulated autophagy modulator protein 1 (Damage-regulated autophagy modulator) | Homo sapiens TI:9606 None |  |  |  | |||||
| DRAM2_HUMAN Ensembl» | 
 | 
 | DRAM2 | DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77) | Homo sapiens TI:9606 None |  |  |  | |||||
| T150A_HUMAN Ensembl» | 
 | 
 | TMEM150A | Transmembrane protein 150A (Transmembrane protein 150) | Homo sapiens TI:9606 None |  |  |  | |||||
| T150B_HUMAN Ensembl» | 
 | 
 | TMEM150B | Modulator of macroautophagy TMEM150B (Protein DRAM-3) (Transmembrane protein 150B) (Transmembrane protein 224) | Homo sapiens TI:9606 None |  |  |  | |||||
| T150C_HUMAN Ensembl» | 
 | 
 | TMEM150C | Transmembrane protein 150C | Homo sapiens TI:9606 None |  |  |  | |||||
| DRAM1_MOUSE Ensembl» | 
 | 
 | Dram1 | DNA damage-regulated autophagy modulator protein 1 (Damage-regulated autophagy modulator) | Mus musculus TI:10090 None |  |  |  | |||||
| DRAM2_MOUSE Ensembl» | 
 | 
 | Dram2 | DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77) | Mus musculus TI:10090 None |  |  |  | |||||
| T150A_MOUSE Ensembl» | 
 | 
 | Tmem150a | Transmembrane protein 150A (Transmembrane protein 150) | Mus musculus TI:10090 None |  |  |  | |||||
| T150B_MOUSE Ensembl» | 
 | 
 | Tmem150b | Modulator of macroautophagy TMEM150B (Transmembrane protein 150B) | Mus musculus TI:10090 None |  |  |  | |||||
| T150C_MOUSE Ensembl» | 
 | 
 | Tmem150c | Transmembrane protein 150C (Tentonin 3) | Mus musculus TI:10090 None |  |  |  | |||||
| B5DEF4_RAT RGD» | 
 | 
 | Dram1 | DNA-damage regulated autophagy modulator 1 (Dram protein) | Rattus norvegicus TI:10116 None |  |  |  | |||||
| D3ZEH7_RAT RGD» | 
 | 
 | Tmem150b | Transmembrane protein 150B | Rattus norvegicus TI:10116 None |  |  | ||||||
| DRAM2_RAT RGD» | 
 | 
 | Dram2 | DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77) | Rattus norvegicus TI:10116 None |  |  |  | |||||
| T150A_RAT RGD» | 
 | 
 | Tmem150a | Transmembrane protein 150A (Fasting-inducible integral membrane protein TM6P1) (Transmembrane protein 150) | Rattus norvegicus TI:10116 None |  |  |  | |||||
| T150C_RAT RGD» | 
 | 
 | Tmem150c | Transmembrane protein 150C | Rattus norvegicus TI:10116 None |  |  |  | |||||
| SFK1_YEAST SGD» | 
 | 
 | SFK1 | Protein SFK1 (Suppressor of four kinase protein 1) | Saccharomyces cerevisiae TI:4932 None |  |  |  | |||||
| SFK1_SCHPO PomBase» | 
 | 
 | sfk1 | Protein sfk1 | Schizosaccharomyces pombe TI:4896 None |  |  |  | |||||