Collated Gene Ontology terms

Biological process: DNA binding(2023, 2025) nucleic acid binding(2025) endonuclease activity(2025) zinc ion binding(2025) chromatin binding(2003, 2025) mRNA binding(2003, 2025) metal ion binding(2025) sequence-specific DNA binding(2009, 2014, 2025) centromeric DNA binding(2009, 2019) RNA polymerase II cis-regulatory region sequence-specific DNA binding(2013, 2025)
satellite DNA binding2003 hydrolase activity2025 cysteine-type deubiquitinase activity2025 chromatin-protein adaptor activity2024 DNA-binding transcription factor activity2025

Molecular function: regulation of DNA-templated transcription2025 segment specification2025 central nervous system formation2025 positive regulation of canonical Wnt signaling pathway2017, 2025 positive regulation of transcription by RNA polymerase II2013 positive regulation of thiamine biosynthetic process2013 donor selection2015, 2024 protein deubiquitination2025 positive regulation of glycolytic fermentation to ethanol2013 negative regulation of rDNA heterochromatin formation2025
chromatin organization2025 central nervous system development2003 DNA biosynthetic process2025

Cellular component: nucleus2003, 2009, 2010, 2013, 2021, 2025 nucleoplasm2024, 2025 chromosome, centromeric region2014, 2025 condensed chromosome, centromeric region2014, 2016, 2019, 2025 nuclear body2024, 2025 chromosome2014, 2025 ribonucleoprotein complex2018, 2025 pericentric heterochromatin2016, 2025 cytoplasm2011, 2025 plasma membrane2025
cytosol2025 chromatin2005, 2018, 2024 mating-type region heterochromatin2015

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 11/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 4/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A0G2KAW9_RAT
RGD»
0.5
Cenpb Major centromere autoantigen B Rattus norvegicus
TI:10116 None
   
A0A0R4IN51_DANRE
ZFIN»
0.5
si:rp71-1d10.8 Si:rp71-1d10.8 Danio rerio
TI:7955 None
 
A0A8D9N0J4_CAEEL
WormBase»
0.0
CELE_Y53G8AM.8 Y53G8AM.8 HTH CENPB-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A0A8V0Y6L1_CHICK
Ensembl»
0.5
TIGD5 Tigger transposable element derived 5 Gallus gallus
TI:9031 None
   
A0A8V1ADK7_CHICK
Ensembl»
0.5
LOC107052490 HTH CENPB-type domain-containing protein Gallus gallus
TI:9031 None
   
A0AB13A8U4_DANRE
ZFIN»
0.0
LOC100150296 Uncharacterized protein LOC100150296 Danio rerio
TI:7955 None
   
A7YY82_RAT
RGD»
1.5
Jrk Jrk helix-turn-helix protein Rattus norvegicus
TI:10116 None
   
ABP1_SCHPO
PomBase»
6.1
abp1 ARS-binding protein 1 Schizosaccharomyces pombe
TI:4896 None
 
B4DSL7_HUMAN
Ensembl»
0.0
hCG_2040263 HCG2040263, isoform CRA_b (cDNA FLJ53537) Homo sapiens
TI:9606 None
 
CBH1_SCHPO
PomBase»
1.3
cbh1 CENP-B homolog protein 1 (CBHP-1) Schizosaccharomyces pombe
TI:4896 None
 
CBH2_SCHPO
PomBase»
0.5
cbh2 CENP-B homolog protein 2 (CBHP-2) Schizosaccharomyces pombe
TI:4896 None
 
CENPB_HUMAN
Ensembl»
3.6
CENPB Major centromere autoantigen B
(Centromere protein B) (CENP-B)		 Homo sapiens
TI:9606 None
 
CENPB_MOUSE
Ensembl»
0.5
Cenpb Major centromere autoantigen B
(Centromere protein B) (CENP-B)		 Mus musculus
TI:10090 None
 
D3ZS21_RAT
RGD»
0.5
Tigd3 Tigger transposable element derived 3 Rattus norvegicus
TI:10116 None
   
D3ZV46_RAT
RGD»
0.5
Pogk Pogo transposable element
derived with KRAB domain		 Rattus norvegicus
TI:10116 None
   
D4AC64_RAT
RGD»
0.5
Tigd4 Tigger transposable element derived 4 Rattus norvegicus
TI:10116 None
   
F1LVC4_RAT
RGD»
0.5
Tigd2 Tigger transposable element derived 2 Rattus norvegicus
TI:10116 None
   
JERKL_HUMAN
Ensembl»
1.4
JRKL Jerky protein homolog-like (Human homolog
of mouse jerky gene protein) (HHMJG)		 Homo sapiens
TI:9606 None
 
JERKL_MOUSE
Ensembl»
0.5
Jrkl Jerky protein homolog-like Mus musculus
TI:10090 None
 
JERKY_HUMAN
Ensembl»
1.3
JRK Jerky protein homolog Homo sapiens
TI:9606 None
 
JERKY_MOUSE
Ensembl»
1.8
Jrk Jerky protein Mus musculus
TI:10090 None
 
M0R5M5_RAT
RGD»
0.5
Jrkl JRK-like Rattus norvegicus
TI:10116 None
   
PDC2_YEAST
SGD»
5.3
PDC2 Protein PDC2 Saccharomyces cerevisiae
TI:4932 None
 
POGK_HUMAN
Ensembl»
0.5
POGK Pogo transposable element with KRAB domain Homo sapiens
TI:9606 None
 
POGK_MOUSE
Ensembl»
0.5
Pogk Pogo transposable element with KRAB domain Mus musculus
TI:10090 None
 
Q19682_CAEEL
WormBase»
0.0
CELE_F21D5.4 F21D5.4 HTH CENPB-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q54C89_DICDI
dictyBase»
0.0
DDB_G0293102 HTH CENPB-type domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q7JR24_DROME
FlyBase»
0.0
cag Cag, isoform A (Cag, isoform B) (RH58567p) Drosophila melanogaster
TI:7227 None
 
Q9N3P2_CAEEL
WormBase»
0.0
CELE_Y48G1C.6 Y48G1C.6 HTH CENPB-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
TIGD1_HUMAN
Ensembl»
0.5
TIGD1 Tigger transposable element-derived protein 1 Homo sapiens
TI:9606 None
 
TIGD2_HUMAN
Ensembl»
0.5
TIGD2 Tigger transposable element-derived protein 2 Homo sapiens
TI:9606 None
 
TIGD2_MOUSE
Ensembl»
0.5
Tigd2 Tigger transposable element-derived protein 2 Mus musculus
TI:10090 None
 
TIGD3_HUMAN
Ensembl»
0.5
TIGD3 Tigger transposable element-derived protein 3 Homo sapiens
TI:9606 None
 
TIGD3_MOUSE
Ensembl»
0.5
Tigd3 Tigger transposable element-derived protein 3 Mus musculus
TI:10090 None
 
TIGD4_HUMAN
Ensembl»
0.5
TIGD4 Tigger transposable element-derived protein 4 Homo sapiens
TI:9606 None
 
TIGD4_MOUSE
Ensembl»
0.5
Tigd4 Tigger transposable element-derived protein 4 Mus musculus
TI:10090 None
 
TIGD5_HUMAN
Ensembl»
0.5
TIGD5 Tigger transposable element-derived protein 5 Homo sapiens
TI:9606 None
 
TIGD5_MOUSE
Ensembl»
0.5
Tigd5 Tigger transposable element derived 5 Mus musculus
TI:10090 None
 
TIGD5_RAT
RGD»
0.5
Tigd5 Tigger transposable element derived 5 Rattus norvegicus
TI:10116 None
 
TIGD6_HUMAN
Ensembl»
0.5
TIGD6 Tigger transposable element-derived protein 6 Homo sapiens
TI:9606 None
 
TIGD7_HUMAN
Ensembl»
0.5
TIGD7 Tigger transposable element-derived protein 7 Homo sapiens
TI:9606 None