Collated Gene Ontology terms

Biological process: NADH dehydrogenase (ubiquinone) activity(2007, 2025) oxidoreductase activity(2025)

Molecular function: mitochondrial electron transport, NADH to ubiquinone2007, 2023, 2024, 2025 respiratory electron transport chain2025 mitochondrial respiratory chain complex I assembly2016, 2021, 2025 protein homooligomerization2025 positive regulation of mitochondrial membrane potential2017, 2025 positive regulation of ATP biosynthetic process2016, 2025 negative regulation of reactive oxygen species biosynthetic process2017, 2025 negative regulation of non-canonical NF-kappaB signal transduction2017, 2025 proton transmembrane transport2025 proton motive force-driven mitochondrial ATP synthesis2025
aerobic respiration2025

Cellular component: respiratory chain complex I2024, 2025 mitochondrial inner membrane2005, 2013, 2024, 2025 cytoplasm2010, 2025 mitochondrion2009, 2024 plasma membrane2016 azurophil granule membrane2016

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A803TU67_ANOCA
Ensembl»
0.0
ndufc2 NADH dehydrogenase [ubiquinone] 1 subunit C2 Anolis carolinensis
TI:28377 None
   
H9GIX9_ANOCA
Ensembl»
0.0
Uncharacterized protein Anolis carolinensis
TI:28377 None
   
Q7QD00_ANOGA
EnsemblMetazoa»
0.0
1273079 NADH dehydrogenase [ubiquinone] 1 subunit C2 Anopheles gambiae
TI:7165 None
 
NDUC2_BOVIN
Ensembl»
0.0
NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2
(Complex I-B14.5b) (CI-B14.5b) (NADH-ubiquinone oxidoreductase subunit B14.5b)		 Bos taurus
TI:9913 None
 
A0A9J7LHL5_BRAFL
euHCVdb»
0.0
LOC118419571 NADH dehydrogenase [ubiquinone]
1 subunit C2-like		 Branchiostoma floridae
TI:7739 None
   
A8X9Q5_CAEBR
WormBase»
0.0
CBG09820 CBG_09820 Protein CBG09820 Caenorhabditis briggsae
TI:6238 None
 
Q9BL33_CAEEL
WormBase»
0.0
nduc-2 NADH dehydrogenase [ubiquinone] 1 subunit C2 Caenorhabditis elegans
TI:6239 None
 
A0A8I3N878_CANLF
Ensembl»
0.0
NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 Canis lupus
TI:9612 None
   
Q5BJK4_DANRE
ZFIN»
0.0
ndufc2 NADH dehydrogenase [ubiquinone] 1 subunit C2 Danio rerio
TI:7955 None
 
E9HFR9_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_329128 NADH dehydrogenase [ubiquinone] 1 subunit C2 Daphnia pulex
TI:6669 None
 
Q9VQM2_DROME
FlyBase»
3.4
ND-B14.5B NADH dehydrogenase [ubiquinone] 1 subunit C2 Drosophila melanogaster
TI:7227 None
 
A0A5F5PYN9_HORSE
Ensembl»
0.0
NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 Equus caballus
TI:9796 None
   
A0ABI7WQY8_FELCA
Ensembl»
0.0
NADH dehydrogenase [ubiquinone] 1 subunit C2 Felis catus
TI:9685 None
   
A0ABI8AGC1_FELCA
Ensembl»
0.0
NADH dehydrogenase [ubiquinone] 1 subunit C2 Felis catus
TI:9685 None
   
A0A1D5NUY6_CHICK
Ensembl»
0.0
NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 Gallus gallus
TI:9031 None
   
G3RCI8_GORGO
Ensembl»
0.0
KCTD14 Potassium channel tetramerization
domain containing 14		 Gorilla gorilla
TI:9593 None
 
NDUC2_GORGO
Ensembl»
0.0
NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2
(Complex I-B14.5b) (CI-B14.5b) (NADH-ubiquinone oxidoreductase subunit B14.5b)		 Gorilla gorilla
TI:9593 None
 
T1FG28_HELRO
EnsemblMetazoa»
0.0
20207777 NADH dehydrogenase [ubiquinone] 1 subunit C2 Helobdella robusta
TI:6412 None
 
KCD14_HUMAN
Ensembl»
0.0
KCTD14 BTB/POZ domain-containing protein KCTD14 Homo sapiens
TI:9606 None
 
NDUC2_HUMAN
Ensembl»
3.2
NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (Human
lung cancer oncogene 1 protein) (HLC-1) (NADH-ubiquinone oxidoreductase subunit B14.5b)		 Homo sapiens
TI:9606 None
 
NDUCR_HUMAN
Ensembl»
0.0
NDUFC2-KCTD14 NADH dehydrogenase [ubiquinone] 1 subunit C2,
isoform 2 (NDUFC2-KCTD14 readthrough transcript protein)		 Homo sapiens
TI:9606 None
 
B7P949_IXOSC
EnsemblMetazoa»
0.0
8026414 NADH:ubiquinone oxidoreductase, NDUFC2/B14.5B
subunit, putative (EC 1.6.5.3)		 Ixodes scapularis
TI:6945 None
 
F7HK78_MACMU
Ensembl»
0.0
NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 Macaca mulatta
TI:9544 None
 
G7NEE9_MACMU
Ensembl»
0.0
KCTD14 Potassium channel tetramerization
domain containing 14		 Macaca mulatta
TI:9544 None
   
A0A5F8GPW4_MONDO
Ensembl»
0.0
NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 Monodelphis domestica
TI:13616 None
   
NDUC2_MOUSE
Ensembl»
3.7
Ndufc2 NADH dehydrogenase [ubiquinone] 1 subunit C2
(Complex I-B14.5b) (CI-B14.5b) (NADH-ubiquinone oxidoreductase subunit B14.5b)		 Mus musculus
TI:10090 None
 
A0A6I8NBA2_ORNAN
Ensembl»
0.0
LOC114805804 NADH dehydrogenase [ubiquinone] 1 subunit C2 Ornithorhynchus anatinus
TI:9258 None
   
H2LCE1_ORYLA
Ensembl»
0.0
NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 Oryzias latipes
TI:8090 None
   
H2Q4G9_PANTR
Ensembl»
0.0
KCTD14 Potassium channel tetramerization
domain containing 14		 Pan troglodytes
TI:9598 None
 
NDUC2_PANTR
Ensembl»
0.0
NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2
(Complex I-B14.5b) (CI-B14.5b) (NADH-ubiquinone oxidoreductase subunit B14.5b)		 Pan troglodytes
TI:9598 None
 
A6I691_RAT
RGD»
4.5
Ndufc2 NADH dehydrogenase [ubiquinone] 1 subunit C2 Rattus norvegicus
TI:10116 None
 
A0A7M7RGN6_STRPU
EnsemblMetazoa»
0.0
NADH dehydrogenase [ubiquinone] 1 subunit C2 Strongylocentrotus purpuratus
TI:7668 None
   
A0A8W4FJS9_PIG
Ensembl»
0.0
NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 Sus scrofa
TI:9823 None
   
D2A2K1_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_07636 NADH dehydrogenase [ubiquinone] 1 subunit C2 Tribolium castaneum
TI:7070 None
 
A0A1B8Y3G3_XENTR
Xenbase»
0.0
ndufc2 NADH dehydrogenase [ubiquinone] 1 subunit C2 Xenopus tropicalis
TI:8364 None
 
A3KMU9_XENLA
Xenbase»
0.0
ndufc2.S NADH dehydrogenase [ubiquinone] 1 subunit C2 Xenopus laevis
TI:8355 None