Collated Gene Ontology terms

Biological process: thyrotropin-releasing hormone receptor binding(2017, 2018, 2024) hormone receptor binding(2018, 2024) hormone activity(2024) protein heterodimerization activity(2017, 2024)

Molecular function: cell surface receptor signaling pathway2017, 2018, 2024 adenylate cyclase-activating G protein-coupled receptor signaling pathway2018, 2024 signal transduction2024 regulation of signal transduction2024

Cellular component: extracellular space2009, 2018, 2024 extracellular region2002, 2016, 2024 membrane2024

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
H9GRI1_ANOCA
Ensembl»
0.0
Glycoprotein hormone subunit alpha 2 Anolis carolinensis
TI:28377 None 		     
Q7PJ83_ANOGA
EnsemblMetazoa»
0.0
1277683 AGAP008301-PA Anopheles gambiae
TI:7165 None
 
E1BD70_BOVIN
Ensembl»
0.0
GPHA2 Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Follicle-stimulating hormone alpha chain) (Follitropin
alpha chain) (Luteinizing hormone alpha chain) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (Thyrotropin alpha chain)		 Bos taurus
TI:9913 None
 
A0A9J7M0X8_BRAFL
CTD»
0.0
LOC118425984 Thyrostimulin alpha-2 subunit-like isoform X1
(Thyrostimulin alpha-2 subunit-like isoform X2)		 Branchiostoma floridae
TI:7739 None 		     
A0A9J7MXJ9_BRAFL
CTD»
0.0
LOC118419879 Thyrostimulin alpha-2 subunit-like Branchiostoma floridae
TI:7739 None 		     
A8Y458_CAEBR
WormBase»
0.0
flr-2 Bursicon (Bursicon subunit alpha) Caenorhabditis briggsae
TI:6238 None
 
Q21013_CAEEL
WormBase»
0.0
flr-2 Bursicon (Bursicon subunit alpha) Caenorhabditis elegans
TI:6239 None
 
F1PIN2_CANLF
Ensembl»
0.0
GPA2 Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Follicle-stimulating hormone alpha chain) (Follitropin
alpha chain) (Luteinizing hormone alpha chain) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (Thyrotropin alpha chain)		 Canis lupus
TI:9612 None
 
F7AY10_CIOIN
Ensembl»
0.0
LOC100178300 Thyrostimulin alpha-2 subunit-like Ciona intestinalis
TI:7719 None
 
C6SUQ4_DANRE
ZFIN»
1.0
gpa2 Glycoprotein hormones alpha chain Danio rerio
TI:7955 None
 
E9GLP7_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_212447 Putative glycoprotein hormone
alpha 2 subunit-related protein		 Daphnia pulex
TI:6669 None
 
A0A6I8WFJ4_DROME
FlyBase»
1.0
Gpa2 Glycoprotein hormone alpha 2 Drosophila melanogaster
TI:7227 None
 
F7BL67_HORSE
Ensembl»
0.0
GPHA2 Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Follicle-stimulating hormone alpha chain) (Follitropin
alpha chain) (Luteinizing hormone alpha chain) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (Thyrotropin alpha chain)		 Equus caballus
TI:9796 None
   
A0A2I2UQD1_FELCA
Ensembl»
0.0
GPHA2 Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Follicle-stimulating hormone alpha chain) (Follitropin
alpha chain) (Luteinizing hormone alpha chain) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (Thyrotropin alpha chain)		 Felis catus
TI:9685 None
 
G3QDN1_GORGO
Ensembl»
0.0
GPHA2 Glycoprotein hormone subunit alpha 2 Gorilla gorilla
TI:9593 None
 
GPHA2_HUMAN
Ensembl»
4.2
GPHA2 Glycoprotein hormone alpha-2 (Putative secreted
protein Zsig51) (Thyrostimulin subunit alpha)		 Homo sapiens
TI:9606 None
 
W5M1U7_LEPOC
Ensembl»
0.0
Glycoprotein hormone subunit alpha 2 Lepisosteus oculatus
TI:7918 None
 
F6XYG4_MACMU
Ensembl»
0.0
GPHA2 Glycoprotein hormone subunit
alpha 2 (Glycoprotein-alpha 2)		 Macaca mulatta
TI:9544 None
 
A0A5F8GII7_MONDO
Ensembl»
0.0
Glycoprotein hormone subunit alpha 2 Monodelphis domestica
TI:13616 None
   
GPHA2_MOUSE
Ensembl»
0.0
Gpha2 Glycoprotein hormone alpha-2 (Putative secreted
protein Zsig51) (Thyrostimulin subunit alpha)		 Mus musculus
TI:10090 None
 
A7RMZ2_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g239481 Uncharacterized protein Nematostella vectensis
TI:45351 None
   
A7RWM7_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g203257 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
A7RWM9_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g203259 DAN domain-containing protein Nematostella vectensis
TI:45351 None
 
A0A6I8PCD6_ORNAN
Ensembl»
0.0
GPHA2 Glycoprotein hormones alpha chain Ornithorhynchus anatinus
TI:9258 None
   
H2LLM9_ORYLA
Ensembl»
0.0
gpha2 GTH-alpha Oryzias latipes
TI:8090 None
   
H2Q412_PANTR
Ensembl»
0.0
GPHA2 Glycoprotein hormone subunit alpha 2 Pan troglodytes
TI:9598 None
 
A0A2A6C1H2_PRIPA
EnsemblMetazoa»
0.0
WBGene00099027 Flr-2 Pristionchus pacificus
TI:54126 None
 
GPHA2_RAT
RGD»
3.0
Gpha2 Glycoprotein hormone alpha-2 (Putative secreted
protein Zsig51) (Thyrostimulin subunit alpha)		 Rattus norvegicus
TI:10116 None
 
C6SUP8_STRPU
EnsemblMetazoa»
0.0
gpa2 Putative glycoprotein hormone-alpha2 Strongylocentrotus purpuratus
TI:7668 None
 
C6SUP9_STRPU
EnsemblMetazoa»
0.0
gpa2 Putative glycoprotein hormone-alpha2 Strongylocentrotus purpuratus
TI:7668 None
 
A0A4X1V5K8_PIG
Ensembl»
0.0
GPHA2 Glycoprotein hormones alpha chain Sus scrofa
TI:9823 None
   
D6X356_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_11941 Glycoprotein hormone alpha 2 Tribolium castaneum
TI:7070 None
 
A0A1L8GJK7_XENLA
Xenbase»
0.0
gpha2.L Glycoprotein hormone alpha-2 Xenopus laevis
TI:8355 None
   
A0A6I8QD90_XENTR
Ensembl»
0.0
gpha2 Glycoprotein hormones alpha chain Xenopus tropicalis
TI:8364 None