Collated Gene Ontology terms

Biological process: ubiquitin protein ligase activity(2014, 2019, 2022, 2023, 2024) transferase activity(2024) metal ion binding(2024) ubiquitin-protein transferase activity(2011, 2024) zinc ion binding(2014) phosphatidylinositol-3-phosphate binding(2024)

Molecular function: proteasome-mediated ubiquitin-dependent protein catabolic process2011, 2022, 2023, 2024 protein K48-linked ubiquitination2011, 2022, 2024 protein ubiquitination2024 positive regulation of toll-like receptor 4 signaling pathway2023, 2024 autophagosome-lysosome fusion2024 cytoskeleton organization2011

Cellular component: membrane2014, 2022, 2024 cytoplasm2014, 2023, 2024 lysosome2024 intracellular membrane-bounded organelle2022, 2023, 2024 endosome2010, 2024 plasma membrane2014, 2023, 2024 protein-containing complex2018, 2024 cytoplasmic vesicle membrane2014, 2024 nucleoplasm2023, 2024 fibrillar center2023, 2024
cytosol2014, 2016, 2024 synapse2024 synaptic vesicle membrane2024 presynaptic membrane2024 lysosomal membrane2024 endosome membrane2024 cell projection2024 bounding membrane of organelle2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
ZNRF1_HUMAN
Ensembl»
4.6
ZNRF1 E3 ubiquitin-protein ligase ZNRF1 (EC 2.3.2.27) (Nerve injury-induced gene 283
protein) (RING-type E3 ubiquitin transferase ZNRF1) (Zinc/RING finger protein 1)		 Homo sapiens
TI:9606 None
 
ZNRF1_MOUSE
Ensembl»
4.6
Znrf1 E3 ubiquitin-protein ligase ZNRF1 (EC 2.3.2.27) (Nerve injury-induced gene 283
protein) (RING-type E3 ubiquitin transferase ZNRF1) (Zinc/RING finger protein 1)		 Mus musculus
TI:10090 None
 
Q6PFI9_DANRE
ZFIN»
1.5
wu:fb37d03 Uncharacterized protein LOC406256 (Zgc:66427) Danio rerio
TI:7955 None
 
Q9W3V3_DROME
FlyBase»
3.8
Dmel\CG14435 Uncharacterized protein, isoform A
(Uncharacterized protein, isoform C)		 Drosophila melanogaster
TI:7227 None
 
ZNRF2_HUMAN
Ensembl»
3.3
ZNRF2 E3 ubiquitin-protein ligase ZNRF2 (EC 2.3.2.27) (Protein Ells2) (RING finger
protein 202) (RING-type E3 ubiquitin transferase ZNRF2) (Zinc/RING finger protein 2)		 Homo sapiens
TI:9606 None
 
A7E2J2_DANRE
ZFIN»
1.5
znrf2a Uncharacterized protein
LOC100124611 (Zgc:171663 protein)		 Danio rerio
TI:7955 None
 
Q75JS0_DICDI
dictyBase»
1.5
DDB_G0272202 C2H2-type zinc finger-containing protein Dictyostelium discoideum
TI:44689 None
 
Q9N4I6_CAEEL
WormBase»
1.5
CELE_Y71F9AL.10 Y71F9AL.10 RING-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
ZNRF1_DANRE
ZFIN»
3.0
znrf1 E3 ubiquitin-protein ligase znrf1 (EC 2.3.2.27) (RING-type
E3 ubiquitin transferase znrf1) (Zinc/RING finger protein 1)		 Danio rerio
TI:7955 None
 
ZNRF2_DANRE
ZFIN»
1.5
znrf2 E3 ubiquitin-protein ligase znrf2 (EC 2.3.2.27) (RING-type
E3 ubiquitin transferase znrf2) (Zinc/RING finger protein 2)		 Danio rerio
TI:7955 None
 
ZNRF2_MOUSE
Ensembl»
0.5
Znrf2 E3 ubiquitin-protein ligase ZNRF2 (EC 2.3.2.27) (RING-type
E3 ubiquitin transferase ZNRF2) (Zinc/RING finger protein 2)		 Mus musculus
TI:10090 None
 
A0A8I6AGK9_RAT
RGD»
4.5
Znrf1 Zinc and ring finger 1 Rattus norvegicus
TI:10116 None
   
A0A8V0YYC5_CHICK
Ensembl»
0.0
ZNRF2 Zinc and ring finger 2 Gallus gallus
TI:9031 None
   
A0A8V0ZW26_CHICK
Ensembl»
0.0
ZNRF1 Zinc and ring finger 1 Gallus gallus
TI:9031 None
   
M0RBD9_RAT
RGD»
2.5
Znrf2 Zinc and ring finger 2 Rattus norvegicus
TI:10116 None