Collated Gene Ontology terms

Biological process: metal ion binding(2024) phosphatidylinositol binding(2024) zinc ion binding(2024) small GTPase binding(2024) RNA polymerase II cis-regulatory region sequence-specific DNA binding(2024) DNA-binding transcription factor activity(2024) ATP hydrolysis activity(2024) ATP binding(2024)

Molecular function: lysosome localization2017, 2021, 2024 positive regulation of ruffle assembly2017, 2024 positive regulation of bone resorption2017, 2024 autophagy2024 myoblast differentiation2018, 2024 late endosome to lysosome transport2021, 2024 autophagosome-lysosome fusion2021, 2024 protein transport2024 regulation of DNA-templated transcription2024 lysosome organization2017

Cellular component: endosome2024 membrane2024 lysosome2021, 2024 cytoplasm2018, 2024 Golgi apparatus2018, 2024 plasma membrane2018, 2024 autolysosome2021, 2024 nucleolus2023, 2024 intracellular membrane-bounded organelle2023, 2024 late endosome membrane2024
autolysosome membrane2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 1/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 18/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
F4JDV4_ARATH
TAIR»
0.0
SNX5 Phox (PX) domain-containing protein Arabidopsis thaliana
TI:3702 None
 
DEFI8_CAEEL
WormBase»
0.0
F20H11.1 Differentially expressed in FDCP 8 homolog Caenorhabditis elegans
TI:6239 None
 
K8ESM7_CAEEL
WormBase»
0.8
cup-14 RUN domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A0A0R4IHS8_DANRE
ZFIN»
0.0
zgc:101815 Differentially expressed in FDCP 8 homolog Danio rerio
TI:7955 None
 
A0A8M9Q8H1_DANRE
ZFIN»
0.0
wu:fc17c08 Pleckstrin homology domain-containing family M member 1 isoform 1 (Pleckstrin homology domain-containing family M
member 1 isoform X1) (Pleckstrin homology domain-containing, family M (with RUN domain) member 1)		 Danio rerio
TI:7955 None
 
B0UYC9_DANRE
ZFIN»
0.0
plekhm3 Novel protein (Pleckstrin homology
domain-containing family M member 3)		 Danio rerio
TI:7955 None
 
DEFI8_DROME
FlyBase»
0.0
DEF8 Differentially expressed in FDCP 8 homolog Drosophila melanogaster
TI:7227 None
 
Q9W293_DROME
FlyBase»
0.8
Plekhm1 Pleckstrin homology and RUN domain containing M1 Drosophila melanogaster
TI:7227 None
 
A0A8V0Y0K9_CHICK
Ensembl»
0.0
DEF8 Differentially expressed in FDCP 8 homolog Gallus gallus
TI:9031 None
   
A0A8V0ZT76_CHICK
Ensembl»
0.0
Pleckstrin homology domain-containing
family M member 1		 Gallus gallus
TI:9031 None
   
A0A8V1A4M8_CHICK
Ensembl»
0.0
PLEKHM3 Pleckstrin homology domain containing M3 Gallus gallus
TI:9031 None
   
A0A8V1A7J0_CHICK
Ensembl»
0.0
PLEKHM1 Pleckstrin homology and RUN domain containing M1 Gallus gallus
TI:9031 None
   
DEFI8_HUMAN
Ensembl»
1.5
DEF8 Differentially expressed in
FDCP 8 homolog (DEF-8)		 Homo sapiens
TI:9606 None
 
PKHM1_HUMAN
Ensembl»
3.9
PLEKHM1 Pleckstrin homology domain-containing family M member 1 (PH domain-containing
family M member 1) (162 kDa adapter protein) (AP162)		 Homo sapiens
TI:9606 None
 
PKHM3_HUMAN
Ensembl»
0.5
PLEKHM3 Pleckstrin homology domain-containing family M member 3 (PH
domain-containing family M member 3) (Differentiation associated protein)		 Homo sapiens
TI:9606 None
 
DEFI8_MOUSE
Ensembl»
2.4
Def8 Differentially expressed in FDCP 8 (DEF-8) Mus musculus
TI:10090 None
 
PKHM1_MOUSE
Ensembl»
3.9
Plekhm1 Pleckstrin homology domain-containing family M member
1 (PH domain-containing family M member 1)		 Mus musculus
TI:10090 None
 
PKHM3_MOUSE
Ensembl»
0.8
Plekhm3 Pleckstrin homology domain-containing family M member 3
(PH domain-containing family M member 3) (Differentiation-associated protein)		 Mus musculus
TI:10090 None
 
D4A959_RAT
RGD»
0.5
Plekhm3 Pleckstrin homology domain containing M3 Rattus norvegicus
TI:10116 None
   
DEFI8_RAT
RGD»
3.0
Def8 Differentially expressed in
FDCP 8 homolog (DEF-8)		 Rattus norvegicus
TI:10116 None
 
PKHM1_RAT
RGD»
5.0
Plekhm1 Pleckstrin homology domain-containing family M member
1 (PH domain-containing family M member 1)		 Rattus norvegicus
TI:10116 None