Collated Gene Ontology terms

Biological process: oxidoreductase activity(2024) alditol:NADP+ 1-oxidoreductase activity(2013, 2017, 2019, 2024) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(2012, 2024) aldo-keto reductase (NADP) activity(2012, 2013, 2014, 2023, 2024) aldose-6-phosphate reductase (NADPH) activity(2024) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(2006, 2024) methylglyoxal reductase (NADPH-dependent, acetol producing)(2013, 2023) D-xylose:NADP reductase activity(2007, 2024) indole-3-acetaldehyde reductase (NADPH) activity(2004, 2024) indole-3-acetaldehyde reductase (NADH) activity(2004, 2024)
L-arabinose:NADP reductase activity2007 2,5-didehydrogluconate reductase activity2024 nucleotide binding2024 mannose-6-phosphate 6-reductase activity2024 alpha-keto ester reductase activity2006, 2013 alpha-keto amide reductase activity2006, 2013 alcohol dehydrogenase (NADP+) activity2014, 2024 sphingosine-1-phosphate receptor activity2020 prostaglandin-F synthase activity2024 prostaglandin H2 endoperoxidase reductase activity2024 methylglyoxal reductase (NADPH-dependent) activity2024 aryl-alcohol dehydrogenase (NADP+) activity2012 adenosine deaminase activity2024 RNA binding2024

Molecular function: methylglyoxal catabolic process2012, 2017, 2023 L-ascorbic acid biosynthetic process2024 arabinose catabolic process2006, 2013, 2024 D-xylose catabolic process2006, 2013, 2024 proteasome-mediated ubiquitin-dependent protein catabolic process2021 prostaglandin biosynthetic process2024 cellular response to oxidative stress2013, 2024 ubiquitin-dependent protein catabolic process2021 cell redox homeostasis2021 sphingosine-1-phosphate receptor signaling pathway2020
regulation of metabolic process2021 monoatomic ion transmembrane transport2024 cellular ketone metabolic process2013 angiogenesis2020 adenylate cyclase-activating G protein-coupled receptor signaling pathway2020 RNA processing2024

Cellular component: cytosol2009, 2014, 2019, 2024 cytoplasm2009, 2014, 2018, 2023, 2024 nucleus2009, 2014, 2018, 2024 plasma membrane2010, 2018, 2023 membrane2024 mitochondrion2019 peptidoglycan-based cell wall2012

Phylogenetic distribution

Chordates: 9/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 3/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 32/39 
Archea: 1/8 
Bacteria: 17/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9SJV1_ARATH
TAIR»
0.0
At2g21260 At2g21260 (NAD(P)-linked oxidoreductase superfamily protein)
(Putative NADPH dependent mannose 6-phosphate reductase)		 Arabidopsis thaliana
TI:3702 None
 
Q9SJV2_ARATH
TAIR»
0.0
At2g21250 NAD(P)-linked oxidoreductase superfamily protein
(Putative NADPH-dependent mannose 6-phosphate reductase)		 Arabidopsis thaliana
TI:3702 None
 
P91997_CAEEL
WormBase»
0.5
CELE_F53F1.2 F53F1.2 NADP-dependent oxidoreductase
domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
P91998_CAEEL
WormBase»
0.5
CELE_F53F1.3 F53F1.3 NADP-dependent oxidoreductase
domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q17568_CAEEL
WormBase»
0.5
C01G5.5 CELE_C01G5.5 NADP-dependent oxidoreductase
domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q18483_CAEEL
WormBase»
0.5
C35D10.6 CELE_C35D10.6 NADP-dependent oxidoreductase
domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q21274_CAEEL
WormBase»
0.5
CELE_K07C5.2 K07C5.2 NADP-dependent oxidoreductase
domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q9U2J5_CAEEL
WormBase»
0.5
CELE_Y39G8B.2 Y39G8B.2 NADP-dependent oxidoreductase
domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
YOF5_CAEEL
WormBase»
0.5
ZK1290.5 Uncharacterized oxidoreductase
ZK1290.5 (EC 1.-.-.-)		 Caenorhabditis elegans
TI:6239 None
 
Q5BLA6_DANRE
ZFIN»
0.5
zgc:110782 Uncharacterized protein LOC541358 (Zgc:110782) Danio rerio
TI:7955 None
 
Q5XJM7_DANRE
ZFIN»
0.5
zgc:101765 Glyoxal reductase-like (Glyoxal
reductase-like isoform X1) (Zgc:101765)		 Danio rerio
TI:7955 None
 
U3JA33_DANRE
ZFIN»
0.5
zgc:110366 Uncharacterized protein LOC550476
isoform 1 (Zgc:110366)		 Danio rerio
TI:7955 None
 
Q54NR0_DICDI
dictyBase»
0.5
alrD Aldo-keto reductase Dictyostelium discoideum
TI:44689 None
 
Q54NR1_DICDI
dictyBase»
0.5
alrE Aldo-keto reductase Dictyostelium discoideum
TI:44689 None
 
Q54NR2_DICDI
dictyBase»
0.5
alrF Aldo-keto reductase Dictyostelium discoideum
TI:44689 None
 
DKGA_ECOLI
EnsemblBacteria»
3.4
dkgA 2,5-diketo-D-gluconic acid reductase A (2,5-DKG reductase
A) (2,5-DKGR A) (25DKGR-A) (EC 1.1.1.274) (AKR5C)		 Escherichia coli
TI:562 None
 
DKGB_ECOLI
EnsemblBacteria»
4.7
dkgB 2,5-diketo-D-gluconic acid reductase B (2,5-DKG reductase
B) (2,5-DKGR B) (25DKGR-B) (EC 1.1.1.346) (AKR5D)		 Escherichia coli
TI:562 None
 
KAR_YEAST
SGD»
5.3
YDL124W NADPH-dependent alpha-keto amide reductase
(AKR-E) (EC 1.2.1.-) (YKAR)		 Saccharomyces cerevisiae
TI:4932 None
 
YJ66_YEAST
SGD»
5.3
YJR096W Uncharacterized oxidoreductase
YJR096W (EC 1.-.-.-)		 Saccharomyces cerevisiae
TI:4932 None
 
I3ACR_SCHPO
PomBase»
3.9
SPAC19G12.09 NAD/NADP-dependent indole-3-acetaldehyde reductase (EC
1.1.1.190) (EC 1.1.1.191) (AKR3C2)		 Schizosaccharomyces pombe
TI:4896 None
 
YER5_SCHPO
PomBase»
2.5
SPAC2F3.05c Uncharacterized oxidoreductase
C2F3.05c (EC 1.-.-.-)		 Schizosaccharomyces pombe
TI:4896 None
 
YHH5_SCHPO
PomBase»
1.5
SPBC28F2.05c Uncharacterized oxidoreductase
C28F2.05 (EC 1.-.-.-)		 Schizosaccharomyces pombe
TI:4896 None
 
YKW2_SCHPO
PomBase»
2.5
SPAP32A8.02 Uncharacterized oxidoreductase
P32A8.02 (EC 1.-.-.-)		 Schizosaccharomyces pombe
TI:4896 None