Biological process: transcription cis-regulatory region binding^{(2018, 2020, 2023)} identical protein binding^{(2021, 2023)} titin binding^{(2011, 2023)} ubiquitin protein ligase activity^{(2017, 2023)} transferase activity⁽²⁰²³⁾ metal ion binding⁽²⁰²³⁾ kinase activity⁽²⁰²³⁾ cullin family protein binding⁽²⁰²³⁾ ubiquitin-protein transferase activity⁽²⁰²³⁾ ubiquitin protein ligase binding⁽²⁰²³⁾
± 7 toxin activity²⁰²³ oxidoreductase activity²⁰²³ glycosyltransferase activity²⁰²³ enzyme binding²⁰²³ chitinase activity²⁰²³ RNA polymerase II-specific DNA-binding transcription factor binding²⁰²¹ 2-alkenal reductase [NAD(P)+] activity²⁰²³

Molecular function: positive regulation of transcription by RNA polymerase II^{2010, 2018, 2023} protein ubiquitination^{2017, 2022, 2023} mitochondrion organization^{2019, 2023} intracellular signal transduction²⁰²³ response to muscle stretch^{2014, 2023} regulation of sarcomere organization^{2014, 2023} fatty acid metabolic process^{2003, 2023} ubiquitin-dependent protein catabolic process²⁰²¹ signal transduction²⁰²³ response to mechanical stimulus^{2009, 2023}
± 21 proteasome-mediated ubiquitin-dependent protein catabolic process^{2021, 2023} cardiac muscle cell differentiation^{2021, 2023} cardiac muscle cell development^{2021, 2023} actin cytoskeleton organization^{2021, 2023} skeletal muscle cell differentiation²⁰²³ phosphorylation²⁰²³ heart looping²⁰²³ skeletal muscle atrophy²⁰²¹ regulation of transcription by RNA polymerase II²⁰²² regulation of cardiac muscle contraction²⁰²⁰ protein localization to T-tubule²⁰²⁰ protein autoubiquitination²⁰²³ positive regulation of vasculogenesis²⁰²³ positive regulation of Wnt signaling pathway, planar cell polarity pathway²⁰²³ positive regulation of DNA-templated transcription²⁰²¹ negative regulation of canonical Wnt signaling pathway²⁰²³ modulation of process of another organism²⁰²³ exocytosis²⁰²³ ecdysis, collagen and cuticulin-based cuticle²⁰¹⁶ chromatin remodeling²⁰¹² carbohydrate metabolic process²⁰²³

Cellular component: nucleus^{2003, 2010, 2020, 2023} nucleoplasm^{2013, 2023} ubiquitin ligase complex^{2017, 2022, 2023} membrane²⁰²³ cytosol^{2011, 2023} cytoplasmic ribonucleoprotein granule²⁰²³ actin cytoskeleton²⁰²³ I band^{2007, 2023} cytoplasm²⁰²³ myofibril^{2009, 2023}
± 18 intercalated disc^{2009, 2023} ATAC complex²⁰²¹ stress fiber²⁰²³ proteasome complex²⁰²³ plasma membrane²⁰²³ other organism cell membrane²⁰²³ mitochondrion²⁰²³ mitochondrial respiratory chain complex IV²⁰²³ mitochondrial membrane²⁰²³ intracellular membrane-bounded organelle²⁰²³ host cell presynaptic membrane²⁰²³ extracellular region²⁰²³ cytoskeleton²⁰²³ cilium²⁰²¹ Z disc²⁰²³ T-tubule²⁰²⁰ Cul5-RING ubiquitin ligase complex²⁰²³ Cul2-RING ubiquitin ligase complex²⁰²³