Collated Gene Ontology terms

Biological process: hydroxypyruvate isomerase activity(2012, 2017, 2019, 2024) isomerase activity(2024) L-ribulose-5-phosphate 3-epimerase activity(2008, 2017, 2021, 2024) intramolecular oxidoreductase activity, interconverting aldoses and ketoses(2024) metal ion binding(2024) zinc ion binding(2024) DNA binding(2024) endonuclease activity(2024) racemase and epimerase activity, acting on carbohydrates and derivatives(2019) protein homodimerization activity(2019)
manganese ion binding2019 lyase activity2024 identical protein binding2020

Molecular function: glyoxylate metabolic process2012, 2017, 2019 L-ascorbic acid metabolic process2008, 2017 carbohydrate metabolic process2024 DNA repair2024 L-ascorbic acid catabolic process2024 inositol metabolic process2024 L-lyxose metabolic process2007

Cellular component: extracellular region2012 cytosol2014

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 19/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
G1KNW7_ANOCA
Ensembl»
0.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22) Anolis carolinensis
TI:28377 None
   
Q7QBM0_ANOGA
EnsemblMetazoa»
0.0
1273774 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Anopheles gambiae
TI:7165 None
 
Q81E84_BACCR
EnsemblBacteria»
0.0
BC_2104 Xylose isomerase-like TIM
barrel domain-containing protein		 Bacillus cereus
TI:1396 None
 
Q8A8Y6_BACTN
EnsemblBacteria»
0.0
BT_1031 Xylose isomerase-like TIM barrel Bacteroides thetaiotaomicron
TI:818 None
 
E1BAZ4_BOVIN
Ensembl»
0.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22) Bos taurus
TI:9913 None
   
Q89QG1_BRADU
EnsemblBacteria»
0.0
hyi Hyi protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q89R43_BRADU
EnsemblBacteria»
0.0
blr2929 Blr2929 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
A0A9J7LLS9_BRAFL
CTD»
0.0
LOC118421810 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Branchiostoma floridae
TI:7739 None
   
A8XW49_CAEBR
WormBase»
0.0
CBG19664 CBG_19664 Protein CBG19664 Caenorhabditis briggsae
TI:6238 None 		 
 
HYI_CAEEL
WormBase»
1.0
C05D11.5 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Caenorhabditis elegans
TI:6239 None
 
A0A8I3P5Z9_CANLF
Ensembl»
0.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22) Canis lupus
TI:9612 None
   
A9WB31_CHLAA
EnsemblBacteria»
0.0
Caur_3641 Hydroxypyruvate isomerase (EC 5.3.1.22) Chloroflexus aurantiacus
TI:1108 None
 
A9WDL2_CHLAA
EnsemblBacteria»
0.0
Caur_0368 Xylose isomerase domain protein TIM barrel Chloroflexus aurantiacus
TI:1108 None
 
A5I6W3_CLOBH
Ensembl»
0.0
CBO3233 Endonuclease Clostridium botulinum
TI:1491 None
 
HYI_DANRE
ZFIN»
1.0
hyi Putative hydroxypyruvate isomerase (EC 5.3.1.22) Danio rerio
TI:7955 None
 
E9FR18_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_190185 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Daphnia pulex
TI:6669 None
 
B8E339_DICTD
EnsemblBacteria»
0.0
Dtur_1640 Xylose isomerase domain protein TIM barrel Dictyoglomus turgidum
TI:513050 None
 
HYI_DROME
FlyBase»
2.0
Gip Putative hydroxypyruvate isomerase (EC 5.3.1.22) (GIP-like
protein) (Transient receptor potential locus C protein)		 Drosophila melanogaster
TI:7227 None
 
F7BY80_HORSE
Ensembl»
0.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22) Equus caballus
TI:9796 None
   
HYI_ECOLI
EnsemblBacteria»
3.4
hyi Hydroxypyruvate isomerase (EC
5.3.1.22) (Glyoxylate-induced protein)		 Escherichia coli
TI:562 None
 
OTNI_ECOLI
EnsemblBacteria»
1.0
otnI 2-oxo-tetronate isomerase (EC 5.3.1.35)
(2-dehydrotetronate isomerase) (Glyoxylate-induced protein YgbM)		 Escherichia coli
TI:562 None
 
SGBU_ECOLI
EnsemblBacteria»
2.3
sgbU Putative L-ribulose-5-phosphate 3-epimerase SgbU
(EC 5.1.3.22) (L-xylulose-5-phosphate 3-epimerase)		 Escherichia coli
TI:562 None
 
ULAE_ECOLI
EnsemblBacteria»
2.6
ulaE L-ribulose-5-phosphate 3-epimerase UlaE (EC 5.1.3.22)
(L-ascorbate utilization protein E) (L-xylulose-5-phosphate 3-epimerase)		 Escherichia coli
TI:562 None
 
YCJR_ECOLI
EnsemblBacteria»
2.4
ycjR 3-dehydro-D-guloside 4-epimerase (EC
5.1.3.-) (3-keto-D-guloside 4-epimerase)		 Escherichia coli
TI:562 None
 
A0A5F5Y491_FELCA
Ensembl»
0.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22) Felis catus
TI:9685 None
 
Q8RHP3_FUSNN
EnsemblBacteria»
0.0
FN1967 Xylose isomerase-like TIM
barrel domain-containing protein		 Fusobacterium nucleatum
TI:851 None 		 
 
A0A8V0ZK35_CHICK
Ensembl»
0.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22) Gallus gallus
TI:9031 None
   
G3RAJ0_GORGO
Ensembl»
0.0
Putative hydroxypyruvate isomerase (EC 5.3.1.22) Gorilla gorilla
TI:9593 None
 
OTNI_HAEIN
EnsemblBacteria»
0.0
otnI 2-oxo-tetronate isomerase (EC
5.3.1.35) (2-dehydrotetronate isomerase)		 Haemophilus influenzae
TI:727 None
 
SGBU_HAEIN
EnsemblBacteria»
0.0
sgbU Putative L-ribulose-5-phosphate 3-epimerase SgbU
(EC 5.1.3.22) (L-xylulose-5-phosphate 3-epimerase)		 Haemophilus influenzae
TI:727 None
 
T1EH13_HELRO
EnsemblMetazoa»
0.0
20195863 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Helobdella robusta
TI:6412 None
 
HYI_HUMAN
Ensembl»
1.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22)
(Endothelial cell apoptosis protein E-CE1)		 Homo sapiens
TI:9606 None
 
B7PC71_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW017424 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Ixodes scapularis
TI:6945 None
 
W5M9Y6_LEPOC
Ensembl»
0.0
Putative hydroxypyruvate isomerase (EC 5.3.1.22) Lepisosteus oculatus
TI:7918 None
 
Q8Y3K0_LISMO
EnsemblBacteria»
0.0
lmo2835 Lmo2835 protein Listeria monocytogenes
TI:1639 None 		 
 
F7GXP8_MACMU
Ensembl»
0.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22) Macaca mulatta
TI:9544 None
   
F6YYI5_MONDO
Ensembl»
0.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22) Monodelphis domestica
TI:13616 None
   
A9UPI3_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_4973 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Monosiga brevicollis
TI:81824 None
 
HYI_MOUSE
CTD»
0.0
Hyi Putative hydroxypyruvate isomerase (EC 5.3.1.22) Mus musculus
TI:10090 None
 
A7RNR7_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g180263 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Nematostella vectensis
TI:45351 None
 
A7T4B2_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g145386 Xylose isomerase-like TIM
barrel domain-containing protein		 Nematostella vectensis
TI:45351 None 		 
 
A0A6I8MYA6_ORNAN
Ensembl»
0.0
Hydroxypyruvate isomerase (putative) Ornithorhynchus anatinus
TI:9258 None
   
H2LDE7_ORYLA
Ensembl»
0.0
hyi Putative hydroxypyruvate isomerase (EC 5.3.1.22) Oryzias latipes
TI:8090 None
   
H2PYV1_PANTR
Ensembl»
0.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22) Pan troglodytes
TI:9598 None
 
A0A2A6B5L2_PRIPA
EnsemblMetazoa»
0.0
WBGene00273940 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Pristionchus pacificus
TI:54126 None
 
Q9I3L1_PSEAE
EnsemblBacteria»
0.0
PA1501 Xylose isomerase-like TIM
barrel domain-containing protein		 Pseudomonas aeruginosa
TI:287 None
 
Q9I5Y6_PSEAE
EnsemblBacteria»
0.0
PA0550 Xylose isomerase-like TIM
barrel domain-containing protein		 Pseudomonas aeruginosa
TI:287 None
 
F1LZJ4_RAT
RGD»
1.0
Hyi Putative hydroxypyruvate isomerase (EC 5.3.1.22) Rattus norvegicus
TI:10116 None
   
Q7UDX1_RHOBA
EnsemblBacteria»
0.0
RB11728 Xylose isomerase-like TIM
barrel domain-containing protein		 Rhodopirellula baltica
TI:265606 None
 
Q7UFX9_RHOBA
EnsemblBacteria»
0.0
RB8266 Xylose isomerase-like TIM
barrel domain-containing protein		 Rhodopirellula baltica
TI:265606 None 		 
 
Q7UG21_RHOBA
EnsemblBacteria»
0.0
RB8188 Probable glyoxylate-induced protein Rhodopirellula baltica
TI:265606 None
 
Q7UHX2_RHOBA
EnsemblBacteria»
0.0
RB12897 Xylose isomerase-like TIM
barrel domain-containing protein		 Rhodopirellula baltica
TI:265606 None 		 
 
Q7UJ78_RHOBA
EnsemblBacteria»
0.0
RB12073 Xylose isomerase-like TIM
barrel domain-containing protein		 Rhodopirellula baltica
TI:265606 None 		 
 
Q7URI8_RHOBA
EnsemblBacteria»
0.0
RB5637 Xylose isomerase-like TIM
barrel domain-containing protein		 Rhodopirellula baltica
TI:265606 None
 
Q7UX44_RHOBA
EnsemblBacteria»
0.0
sgbU Probable hexulose-6-phosphate
isomerase (EC 5.-.-.-)		 Rhodopirellula baltica
TI:265606 None
 
Q7UZ41_RHOBA
EnsemblBacteria»
0.0
RB201 Sugar phosphate isomerase/epimerase (EC 5.3.1.-) Rhodopirellula baltica
TI:265606 None
 
B9TEG1_RICCO
EnsemblBacteria»
0.0
RCOM_1949840 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Ricinus communis
TI:3988 None
 
Q8ZK48_SALTY
EnsemblBacteria»
0.0
STM4435 Cytoplasmic protein Salmonella typhimurium
TI:28901 None
 
Q8ZL76_SALTY
EnsemblBacteria»
0.0
sgbU 3-hexulose-6-phosphate isomerase (EC 5.-.-.-) Salmonella typhimurium
TI:28901 None
 
Q8ZMG6_SALTY
EnsemblBacteria»
0.0
ygbM Endonuclease Salmonella typhimurium
TI:28901 None
 
Q8ZR84_SALTY
EnsemblBacteria»
0.0
gip Glyoxylate-induced protein Salmonella typhimurium
TI:28901 None
 
ULAE_SALTY
EnsemblBacteria»
0.0
ulaE L-ribulose-5-phosphate 3-epimerase UlaE (EC 5.1.3.22)
(L-ascorbate utilization protein E) (L-xylulose-5-phosphate 3-epimerase)		 Salmonella typhimurium
TI:28901 None
 
A0A494G9U2_SOLLC
EnsemblPlants»
0.0
Xylose isomerase-like TIM
barrel domain-containing protein		 Solanum lycopersicum
TI:4081 None 		     
Q8DN98_STRR6
EnsemblBacteria»
0.0
sga Hexulose-6-phosphate isomerase (EC 5.-.-.-) Streptococcus pneumoniae
TI:1313 None
 
Q93JA5_STRCO
EnsemblBacteria»
0.0
SCO7491 Xylose isomerase-like TIM
barrel domain-containing protein		 Streptomyces coelicolor
TI:1902 None 		 
 
Y6206_STRCO
EnsemblBacteria»
0.0
SCO6206 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Streptomyces coelicolor
TI:1902 None
 
A0A7M7GNL2_STRPU
EnsemblMetazoa»
0.0
Putative hydroxypyruvate isomerase (EC 5.3.1.22) Strongylocentrotus purpuratus
TI:7668 None
   
F1S325_PIG
Ensembl»
0.0
HYI Putative hydroxypyruvate isomerase (EC 5.3.1.22) Sus scrofa
TI:9823 None
   
Y1304_SYNY3
EnsemblBacteria»
0.0
sll1304 Probable ketose 3-epimerase (EC 5.1.3.-) Synechocystis sp.
TI:1148 None
 
IOLO_THEMA
EnsemblBacteria»
0.0
iolO 5-keto-L-gluconate epimerase (EC 5.1.3.-) (Bifunctional nonphosphorylated sugar isomerase) (D-erythrose/D-threose isomerase) (L-ribulose 3-epimerase)
(R3E) (Nonphosphorylated sugar 3-epimerase) (EC 5.1.3.-) (Nonphosphorylated sugar aldose-ketose isomerase) (EC 5.3.1.-)		 Thermotoga maritima
TI:2336 None
 
D6WIB1_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_30659 Putative hydroxypyruvate isomerase (EC 5.3.1.22) Tribolium castaneum
TI:7070 None
 
Q9KMS9_VIBCH
EnsemblBacteria»
0.0
VC_A0241 Hexulose-6-phosphate isomerase SgbU, putative Vibrio cholerae
TI:666 None
 
A0A8J0SKJ0_XENTR
Xenbase»
0.0
hyi Hydroxypyruvate isomerase isoform X1 Xenopus tropicalis
TI:8364 None
   
A0A8J0UYX3_XENLA
Xenbase»
0.0
hyi.L Putative hydroxypyruvate isomerase (EC 5.3.1.22) Xenopus laevis
TI:8355 None
   
HYI_XENLA
Xenbase»
0.0
hyi Putative hydroxypyruvate isomerase (EC 5.3.1.22) Xenopus laevis
TI:8355 None
 
A0A2S9PME1_YERPE
EnsemblBacteria»
0.0
sgbU Hexulose-6-phosphate isomerase (EC 5.-.-.-) Yersinia pestis
TI:632 None
 
Q0WHH1_YERPE
EnsemblBacteria»
0.0
YPO1238 Hydroxypyruvate isomerase Yersinia pestis
TI:632 None