Biological process: transcription cis-regulatory region binding^{(2009, 2012, 2018, 2020, 2024)} sequence-specific DNA binding^{(2006, 2008, 2011, 2018, 2024)} SMAD binding^{(2006, 2011, 2014, 2024)} DNA-binding transcription factor activity^{(2003, 2009, 2024)} DNA-binding transcription activator activity, RNA polymerase II-specific^{(2013, 2018, 2020, 2024)} DNA binding^{(2005, 2009, 2024)} R-SMAD binding^{(2009, 2012, 2024)} protein domain specific binding^{(2006, 2024)} nuclear androgen receptor binding^{(2012, 2024)} co-SMAD binding^{(2012, 2024)}
± 8 bHLH transcription factor binding^{2014, 2024} DNA-binding transcription factor binding^{2021, 2024} DNA-binding transcription factor activity, RNA polymerase II-specific^{2007, 2019, 2023} RNA polymerase II cis-regulatory region sequence-specific DNA binding²⁰²³ RNA polymerase II-specific DNA-binding transcription factor binding²⁰²¹ cis-regulatory region sequence-specific DNA binding²⁰¹⁹ RNA polymerase II transcription regulatory region sequence-specific DNA binding²⁰¹⁸ DNA-binding transcription repressor activity, RNA polymerase II-specific²⁰¹⁸

Molecular function: positive regulation of transcription by RNA polymerase II^{2006, 2009, 2012, 2017, 2018, 2020, 2024} transforming growth factor beta receptor signaling pathway^{2006, 2012, 2018, 2020, 2024} regulation of DNA-templated transcription^{2003, 2024} regulation of transcription by RNA polymerase II^{2003, 2007, 2024} positive regulation of DNA-templated transcription^{2006, 2009, 2024} cellular response to cytokine stimulus^{2017, 2024} negative regulation of transcription by RNA polymerase II^{2007, 2008, 2018, 2024} heart looping^{2010, 2012, 2023, 2024} ventricular trabecula myocardium morphogenesis^{2012, 2023, 2024} secondary heart field specification^{2012, 2023, 2024}
± 42 outflow tract morphogenesis^{2012, 2023, 2024} determination of left/right symmetry^{2003, 2006, 2024} cardiac right ventricle morphogenesis^{2012, 2023, 2024} aorta morphogenesis^{2012, 2023, 2024} negative regulation of intracellular estrogen receptor signaling pathway^{2012, 2024} negative regulation of androgen receptor signaling pathway^{2012, 2024} embryonic heart tube anterior/posterior pattern specification^{2020, 2024} axial mesoderm development^{2006, 2024} anterior/posterior pattern specification^{2003, 2024} negative regulation of DNA-binding transcription factor activity^{2012, 2024} cell differentiation²⁰²⁴ anatomical structure morphogenesis²⁰²⁴ hepatocyte differentiation^{2023, 2024} gastrulation²⁰²⁴ gastrulation with mouth forming second²⁰⁰⁶ activin receptor signaling pathway²⁰⁰⁹ specification of animal organ position²⁰⁰⁴ somite rostral/caudal axis specification²⁰¹¹ regulation of gene expression²⁰¹¹ regulation of BMP signaling pathway²⁰¹⁴ prechordal plate formation²⁰¹¹ notochord formation²⁰¹¹ notochord development²⁰¹⁵ nodal signaling pathway²⁰²³ mesodermal cell fate specification²⁰⁰⁶ mesoderm formation²⁰¹¹ mesendoderm development²⁰¹¹ lens placode formation involved in camera-type eye formation²⁰¹⁵ hypothalamus development²⁰¹⁶ floor plate formation²⁰⁰⁸ floor plate development²⁰¹⁵ endoderm formation²⁰¹¹ embryonic heart tube morphogenesis²⁰⁰⁶ embryonic heart tube left/right pattern formation²⁰¹¹ dorsal/ventral pattern formation²⁰¹¹ determination of left/right asymmetry in lateral mesoderm²⁰²³ cell migration involved in gastrulation²⁰⁰⁸ brain morphogenesis²⁰¹⁶ blood vessel development²⁰⁰⁷ axial mesodermal cell fate specification²⁰¹¹ axial mesoderm morphogenesis²⁰¹¹ Spemann organizer formation at the embryonic shield²⁰¹¹

Cellular component: activin responsive factor complex^{2006, 2009, 2012, 2020, 2024} nucleus^{2003, 2006, 2007, 2012, 2024} transcription regulator complex^{2008, 2009, 2020, 2024} chromatin^{2014, 2018, 2019, 2024} nucleoplasm²⁰¹¹