Collated Gene Ontology terms

Biological process: N-acylneuraminate cytidylyltransferase activity(2007, 2010, 2012, 2015, 2023, 2024) nucleotidyltransferase activity(2024) hydrolase activity(2024) hydrolase activity, acting on ester bonds(2024) metal ion binding(2024) 3-deoxy-manno-octulosonate-8-phosphatase activity(2024) transferase activity(2024) keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity(2015) N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity(2015) N-acylneuraminate-9-phosphatase activity(2024)

Molecular function: N-acetylneuraminate metabolic process2024 lipopolysaccharide biosynthetic process2024 CMP-N-acetylneuraminate biosynthetic process2002, 2024 glycosylation2024 response to heat2013 protein glycosylation2024 chemical synaptic transmission2013

Cellular component: nucleus2002, 2012, 2014, 2024 cytoplasm2012, 2024 membrane2014, 2024 trans-Golgi network2013 synapse2024 nucleoplasm2013 cytosol2014 Golgi apparatus2022

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 1/8 
Bacteria: 22/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A803STF5_ANOCA
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Anolis carolinensis
TI:28377 None
   
A0A1S4GLW4_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
O67920_AQUAE
EnsemblBacteria»
0.0
aq_2171 3-deoxy-D-manno-octulosonate
8-phosphate phosphatase		 Aquifex aeolicus
TI:63363 None
 
KDGGP_BACTN
EnsemblBacteria»
0.0
BT_1713 2-keto-3-deoxy-D-glycero-D-galacto-9-phosphonononic acid phosphatase (KDN-9-P phosphatase) (EC
3.1.3.103) (2-keto-3-deoxy-D-glycero-D-galacto-nonic acid-9-phosphate phosphatase) (KDN9PP) (3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphatase)		 Bacteroides thetaiotaomicron
TI:818 None
 
Q8A748_BACTN
EnsemblBacteria»
0.0
BT_1677 Hydrolase Bacteroides thetaiotaomicron
TI:818 None
 
NEUA_BOVIN
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase (EC 2.7.7.43)
(CMP-N-acetylneuraminic acid synthase) (CMP-NeuNAc synthase)		 Bos taurus
TI:9913 None
 
H7C812_BRADU
EnsemblBacteria»
0.0
ptmB Posttranslational modification protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q89HL8_BRADU
EnsemblBacteria»
0.0
neuA NeuA protein Bradyrhizobium diazoefficiens
TI:1355477 None 		 
 
A0A9J7HQS7_BRAFL
CTD»
0.0
LOC118406623 N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7HT52_BRAFL
CTD»
0.0
LOC118406756 N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7KAY6_BRAFL
CTD»
0.0
LOC118407224 N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7LLH3_BRAFL
CTD»
0.0
LOC118421524 N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7NBR4_BRAFL
CTD»
0.0
LOC118431440 N-acylneuraminate cytidylyltransferase-like Branchiostoma floridae
TI:7739 None
   
A0A8I3NVQ5_CANLF
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase (EC
2.7.7.43) (CMP-N-acetylneuraminic acid synthase)		 Canis lupus
TI:9612 None
   
Q0E670_CIOIN
Ensembl»
0.0
cmas Putative CMP-sialic acid synthetase Ciona intestinalis
TI:7719 None 		 
 
Q83DI2_COXBU
EnsemblBacteria»
0.0
CBU_0749 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
(EC 3.1.3.45) (KDO 8-P phosphatase)		 Coxiella burnetii
TI:777 None
 
NEUAA_DANRE
ZFIN»
1.3
cmasa N-acylneuraminate cytidylyltransferase A (EC
2.7.7.43) (CMP-sialic acid synthetase 1)		 Danio rerio
TI:7955 None
 
NEUAB_DANRE
ZFIN»
1.3
cmasb N-acylneuraminate cytidylyltransferase B (EC
2.7.7.43) (CMP-sialic acid synthetase 2)		 Danio rerio
TI:7955 None
 
E9FTA5_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_310334 N-acylneuraminate cytidylyltransferase Daphnia pulex
TI:6669 None 		 
 
Q8IQV0_DROME
FlyBase»
5.3
Csas CMP-sialic acid synthase (EC 2.7.7.43) Drosophila melanogaster
TI:7227 None
 
F6VQY1_HORSE
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase (EC
2.7.7.43) (CMP-N-acetylneuraminic acid synthase)		 Equus caballus
TI:9796 None
   
KDSC_ECOLI
EnsemblBacteria»
0.0
kdsC 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
(EC 3.1.3.45) (KDO 8-P phosphatase)		 Escherichia coli
TI:562 None
 
M3WCA2_FELCA
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase (EC
2.7.7.43) (CMP-N-acetylneuraminic acid synthase)		 Felis catus
TI:9685 None
 
Q8RGS1_FUSNN
EnsemblBacteria»
0.0
FN0213 N-acylneuraminate-9-phosphatase (EC 3.1.3.29) Fusobacterium nucleatum
TI:851 None
 
A0A8V0YDW2_CHICK
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Gallus gallus
TI:9031 None 		     
Q74BR9_GEOSL
EnsemblBacteria»
0.0
GSU1972 N-acetylneuraminate cytidylyltransferase Geobacter sulfurreducens
TI:35554 None
 
Q74BY6_GEOSL
EnsemblBacteria»
0.0
kdsC 3-deoxy-D-manno-octulosonate-8-phosphate
phosphatase		 Geobacter sulfurreducens
TI:35554 None
 
Q7NEV3_GLOVI
EnsemblBacteria»
0.0
glr3775 Glr3775 protein Gloeobacter violaceus
TI:33072 None
 
G3RGF5_GORGO
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase (EC
2.7.7.43) (CMP-N-acetylneuraminic acid synthase)		 Gorilla gorilla
TI:9593 None
 
KDSC_HAEIN
EnsemblBacteria»
0.0
HI_1679 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
(EC 3.1.3.45) (KDO 8-P phosphatase)		 Haemophilus influenzae
TI:727 None
 
NEUA_HAEIN
EnsemblBacteria»
0.0
neuA Probable N-acylneuraminate cytidylyltransferase (EC 2.7.7.43) (CMP-N-acetylneuraminic
acid synthase) (CMP-NeuNAc synthase) (CMP-sialic acid synthase)		 Haemophilus influenzae
TI:727 None
 
O26090_HELPY
EnsemblBacteria»
0.0
HP_1570 Uncharacterized protein Helicobacter pylori
TI:210 None
 
PSEFG_HELPY
EnsemblBacteria»
0.0
HP_0326 Pseudaminic acid cytidylyltransferase and UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase [Includes: Pseudaminic acid cytidylyltransferase (EC 2.7.7.81) (Pseudaminic acid biosynthesis protein F)
(PseF) (Pseudaminic acid cytidylyltransferase HP_0326A); UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase (EC 3.6.1.57) (Pseudaminic acid biosynthesis protein G) (PseG) (UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase HP_0326B)]		 Helicobacter pylori
TI:210 None
 
NEUA_HUMAN
Ensembl»
2.1
CMAS N-acylneuraminate cytidylyltransferase (EC 2.7.7.43)
(CMP-N-acetylneuraminic acid synthase) (CMP-NeuNAc synthase)		 Homo sapiens
TI:9606 None
 
B7Q984_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW021121 Cmp-N-acetylneuraminic acid synthase, putative (EC
2.7.7.43) (Cmp-N-acetylneuraminic acid synthase, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
W5NE59_LEPOC
Ensembl»
0.0
N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Lepisosteus oculatus
TI:7918 None
 
Q8F5Q2_LEPIN
EnsemblBacteria»
0.0
neuA CMP-N-acetylneuraminic acid synthetase Leptospira interrogans
TI:173 None
 
Q8F5R2_LEPIN
EnsemblBacteria»
0.0
neuA CMP-N-acetylneuraminic acid synthetase Leptospira interrogans
TI:173 None
 
F7H7Q2_MACMU
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase (EC
2.7.7.43) (CMP-N-acetylneuraminic acid synthase)		 Macaca mulatta
TI:9544 None
 
Q8TJL6_METAC
EnsemblBacteria»
0.0
neuA N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Methanosarcina acetivorans
TI:2214 None
 
F7EKV2_MONDO
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase (EC
2.7.7.43) (CMP-N-acetylneuraminic acid synthase)		 Monodelphis domestica
TI:13616 None
   
NEUA_MOUSE
AG»
1.0
Cmas N-acylneuraminate cytidylyltransferase (EC 2.7.7.43)
(CMP-N-acetylneuraminic acid synthase) (CMP-NeuNAc synthase)		 Mus musculus
TI:10090 None
 
NEUA_NEIMB
EnsemblBacteria»
0.0
neuA N-acylneuraminate cytidylyltransferase (EC 2.7.7.43) (CMP-N-acetylneuraminic acid
synthase) (CMP-NeuNAc synthase) (CMP-sialic acid synthase)		 Neisseria meningitidis
TI:487 None
 
Q9K137_NEIMB
EnsemblBacteria»
0.0
NMB0353 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
(EC 3.1.3.45) (KDO 8-P phosphatase)		 Neisseria meningitidis
TI:487 None
 
F7FSB7_ORNAN
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase (EC
2.7.7.43) (CMP-N-acetylneuraminic acid synthase)		 Ornithorhynchus anatinus
TI:9258 None
   
A0A3B3H8E0_ORYLA
Ensembl»
0.0
cmas N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Oryzias latipes
TI:8090 None
   
H2Q5L3_PANTR
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase (EC
2.7.7.43) (CMP-N-acetylneuraminic acid synthase)		 Pan troglodytes
TI:9598 None
 
Q9HVV9_PSEAE
EnsemblBacteria»
0.0
PA4458 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
(EC 3.1.3.45) (KDO 8-P phosphatase)		 Pseudomonas aeruginosa
TI:287 None
 
NEUA_RAT
RGD»
0.5
Cmas N-acylneuraminate cytidylyltransferase (EC 2.7.7.43)
(CMP-N-acetylneuraminic acid synthase) (CMP-NeuNAc synthase)		 Rattus norvegicus
TI:10116 None
 
Q7UL05_RHOBA
EnsemblBacteria»
0.0
RB9821 3-deoxy-manno-octulosonate-8-phosphatase Rhodopirellula baltica
TI:265606 None
 
KDSC_SALTY
EnsemblBacteria»
0.0
kdsC 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
(EC 3.1.3.45) (KDO 8-P phosphatase)		 Salmonella typhimurium
TI:28901 None
 
Q8EAE9_SHEON
EnsemblPlants»
0.0
kdsC 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
(EC 3.1.3.45) (KDO 8-P phosphatase)		 Shewanella oneidensis
TI:70863 None
 
Q9AK46_STRCO
EnsemblBacteria»
0.0
SCO4880 N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Streptomyces coelicolor
TI:1902 None
 
A0A7M7NRH2_STRPU
EnsemblMetazoa»
0.0
N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Strongylocentrotus purpuratus
TI:7668 None
   
Q0E669_STRPU
EnsemblMetazoa»
0.0
cmas N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Strongylocentrotus purpuratus
TI:7668 None
 
A0A287BS35_PIG
Ensembl»
0.0
CMAS N-acylneuraminate cytidylyltransferase (EC
2.7.7.43) (CMP-N-acetylneuraminic acid synthase)		 Sus scrofa
TI:9823 None
   
P73989_SYNY3
EnsemblBacteria»
0.0
slr2122 Slr2122 protein Synechocystis sp.
TI:1148 None
 
B5YJB2_THEYD
EnsemblBacteria»
0.0
THEYE_A0482 N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Thermodesulfovibrio yellowstonii
TI:28262 None
 
D6WYC9_TRICA
EnsemblMetazoa»
0.0
GLEAN_15995 N-acylneuraminate
cytidylyltransferase-like Protein		 Tribolium castaneum
TI:7070 None
 
Q9KP52_VIBCH
EnsemblBacteria»
0.0
VC_2524 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
(EC 3.1.3.45) (KDO 8-P phosphatase)		 Vibrio cholerae
TI:666 None
 
Q8P716_XANCP
EnsemblBacteria»
0.0
XCC2798 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
(EC 3.1.3.45) (KDO 8-P phosphatase)		 Xanthomonas campestris
TI:339 None
 
A0A1L8GVU4_XENLA
Xenbase»
0.0
cmas.L N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Xenopus laevis
TI:8355 None
   
Q0E672_XENTR
Xenbase»
0.0
cmas N-acylneuraminate cytidylyltransferase
(EC 2.7.7.43)		 Xenopus tropicalis
TI:8364 None
 
KDSC_YERPE
EnsemblBacteria»
0.0
kdsC 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
(EC 3.1.3.45) (KDO 8-P phosphatase)		 Yersinia pestis
TI:632 None