Collated Gene Ontology terms

Biological process: zinc ion binding(2025) metal ion binding(2025) RNA polymerase II cis-regulatory region sequence-specific DNA binding(2017, 2020, 2021, 2022, 2023, 2024, 2025) DNA-binding transcription factor activity, RNA polymerase II-specific(2020, 2022, 2023, 2024, 2025) DNA binding(2025) RNA polymerase II transcription regulatory region sequence-specific DNA binding(2020, 2022, 2023, 2025) DNA-binding transcription factor activity(2017, 2020, 2023, 2025) DNA-binding transcription activator activity, RNA polymerase II-specific(2021, 2025) transcription cis-regulatory region binding(2017, 2018, 2025) sequence-specific DNA binding(2022, 2025)
DNA-binding transcription repressor activity, RNA polymerase II-specific2017, 2021, 2025 sequence-specific double-stranded DNA binding2025 identical protein binding2025 transferase activity2025 ubiquitin protein ligase activity2025 transcription coactivator activity2022 single-stranded RNA binding2015 nucleic acid binding2025 methyltransferase activity2025 double-stranded RNA binding2015 chromatin binding2011 RNA binding2025

Molecular function: regulation of transcription by RNA polymerase II2020, 2022, 2023, 2025 DNA-templated transcription2025 regulation of DNA-templated transcription2009, 2017, 2025 positive regulation of transcription by RNA polymerase II2022, 2025 regulation of primary metabolic process2025 regulation of macromolecule metabolic process2025 negative regulation of transcription by RNA polymerase II2017, 2024, 2025 regulation of gluconeogenesis2021, 2025 chromatin organization2025 regulation of gene expression2024
positive regulation of DNA-templated transcription2025 negative regulation of DNA-templated transcription2020, 2025 regulation of development, heterochronic2015 sex differentiation2025 response to heat2015 regulation of translation2025 regulation of non-canonical Wnt signaling pathway2011 regulation of neural precursor cell proliferation2025 regulation of immune system process2025 regulation of fatty acid transport2025 regulation of cytokine production2022 regulation of canonical Wnt signaling pathway2011 negative regulation of gene expression2015 methylation2025 imaginal disc-derived wing vein specification2012 epithelial tube morphogenesis2025 embryonic viscerocranium morphogenesis2013 embryonic neurocranium morphogenesis2013 embryonic digestive tract morphogenesis2007 embryonic cranial skeleton morphogenesis2013 dosage compensation by hypoactivation of X chromosome2025 determination of adult lifespan2015 dendrite morphogenesis2013 central nervous system development2025 cell differentiation2025 asymmetric neuroblast division2025 Ras protein signal transduction2012

Cellular component: nucleus2011, 2012, 2015, 2017, 2022, 2023, 2024, 2025 nucleoplasm2024, 2025 nucleolus2024, 2025 kinetochore2025 chromosome2025 nuclear speck2010, 2025 cytoplasm2015, 2025 transcription regulator complex2017 protein-containing complex2009 nuclear lumen2025
mediator complex2022 euchromatin2011 chromatin2025 PcG protein complex2017

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 3/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SEA2_CAEEL
WormBase»
7.4
sea-2 Signal element on autosome protein 2 Caenorhabditis elegans
TI:6239 None
 
F1Q8J8_DANRE
ZFIN»
6.3
prdm5 PR domain zinc finger protein
5 (PR domain-containing protein 5)		 Danio rerio
TI:7955 None
 
ZN692_HUMAN
Ensembl»
4.7
ZNF692 Zinc finger protein 692
(AICAR responsive element binding protein)		 Homo sapiens
TI:9606 None
 
SYD9_CAEEL
WormBase»
1.5
syd-9 Zinc finger protein syd-9
(Synapse defective protein 9)		 Caenorhabditis elegans
TI:6239 None
 
Z518A_HUMAN
Ensembl»
1.0
ZNF518A Zinc finger protein 518A Homo sapiens
TI:9606 None
 
B3DK35_DANRE
ZFIN»
1.5
plagl2 Pleiomorphic adenoma gene-like 2 (Zinc
finger protein PLAGL2 isoform X1)		 Danio rerio
TI:7955 None
 
Q9V3X8_DROME
FlyBase»
3.8
EG:BACR42I17.11 EG:BACR42I17.11 protein (RE55560p) (Uncharacterized protein,
isoform A) (Uncharacterized protein, isoform D)		 Drosophila melanogaster
TI:7227 None
 
B9A0M7_DROME
FlyBase»
3.0
BcDNA:LD21969 AT31036p (Uncharacterized protein, isoform
D) (Uncharacterized protein, isoform E)		 Drosophila melanogaster
TI:7227 None
 
Q9VKC4_DROME
FlyBase»
3.1
Plzf FI01124p (Promyelocytic leukemia zinc finger, isoform
A) (Promyelocytic leukemia zinc finger, isoform B)		 Drosophila melanogaster
TI:7227 None
 
Q9W3T3_DROME
FlyBase»
3.0
Dmel\CG3032 FI01031p (Uncharacterized protein, isoform
A) (Uncharacterized protein, isoform B)		 Drosophila melanogaster
TI:7227 None
 
ZFP3_HUMAN
Ensembl»
1.5
ZFP3 Zinc finger protein 3 homolog
(Zfp-3) (Zinc finger protein 752)		 Homo sapiens
TI:9606 None
 
ZN554_HUMAN
Ensembl»
1.5
ZNF554 Zinc finger protein 554 Homo sapiens
TI:9606 None
 
ZN576_HUMAN
Ensembl»
0.6
ZNF576 Zinc finger protein 576 Homo sapiens
TI:9606 None
 
Q9VHA4_DROME
FlyBase»
3.0
Dmel\CG8319 LP19870p Drosophila melanogaster
TI:7227 None
 
Q9VL91_DROME
FlyBase»
1.5
zf30C LD23102p (Zinc finger protein 30C) Drosophila melanogaster
TI:7227 None
 
Q9W137_DROME
FlyBase»
3.5
Cg4707 LD29879p Drosophila melanogaster
TI:7227 None
 
Y2744_DROME
FlyBase»
0.0
CG12744 Uncharacterized zinc finger protein CG12744 Drosophila melanogaster
TI:7227 None
 
ZN692_RAT
RGD»
3.0
Znf692 Zinc finger protein 692
(AICAR responsive element binding protein)		 Rattus norvegicus
TI:10116 None
 
A0A0B4KER0_DROME
FlyBase»
3.9
row Relative of woc, isoform C Drosophila melanogaster
TI:7227 None
 
E7FE67_DANRE
ZFIN»
1.5
si:dkey-79d12.4 Si:dkey-79d12.4 Danio rerio
TI:7955 None
 
H0WE71_DANRE
ZFIN»
1.5
si:dkey-72l17.6 Si:dkey-72l17.6 (Uncharacterized
protein LOC503712)		 Danio rerio
TI:7955 None
 
H2KYB3_CAEEL
WormBase»
2.3
sup-37 C2H2-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q21777_CAEEL
WormBase»
1.5
ztf-15 C2H2-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q21907_CAEEL
WormBase»
1.5
CELE_R10E4.11 R10E4.11 C2H2-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q9GZC9_CAEEL
WormBase»
1.5
C04F5.9 CELE_C04F5.9 C2H2-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q9VAT1_DROME
FlyBase»
2.5
Dmel\CG1647 Uncharacterized protein, isoform A Drosophila melanogaster
TI:7227 None
 
A0A8M1PU54_DANRE
ZFIN»
1.5
si:cabz01069015.1 Uncharacterized protein si:cabz01069015.1 Danio rerio
TI:7955 None
   
A0A8M1RSI6_DANRE
ZFIN»
1.5
LOC100537572 C2H2-type domain-containing protein Danio rerio
TI:7955 None
   
A0A8M2BLL3_DANRE
euHCVdb»
1.5
LOC101882607 C2H2-type domain-containing protein Danio rerio
TI:7955 None
   
A0A8M9PS36_DANRE
ZFIN»
1.5
LOC100007966 Zinc finger protein 567 Danio rerio
TI:7955 None
   
A0A8M9PUR8_DANRE
ZFIN»
1.5
znf276 Zinc finger protein 276 Danio rerio
TI:7955 None
   
A0A8M9Q7C6_DANRE
euHCVdb»
1.5
LOC101885920 C2H2-type domain-containing protein Danio rerio
TI:7955 None
   
A0A8V0X551_CHICK
Ensembl»
1.5
C2H2-type domain-containing protein Gallus gallus
TI:9031 None
   
A0A8V0X6Q1_CHICK
Ensembl»
1.5
ZNFB3 MHCB zinc finger protein 3 Gallus gallus
TI:9031 None
   
A0AB32TKY4_DANRE
ZFIN»
0.0
znf977 Uncharacterized protein znf977 Danio rerio
TI:7955 None
   
A0AB32TMB4_DANRE
euHCVdb»
0.0
LOC137490842 Uncharacterized protein isoform X1 Danio rerio
TI:7955 None
   
A0AB32TP56_DANRE
euHCVdb»
0.0
LOC137491257 C2H2-type domain-containing protein Danio rerio
TI:7955 None
   
A0AB32TQF7_DANRE
euHCVdb»
0.0
LOC137491087 C2H2-type domain-containing protein Danio rerio
TI:7955 None