Collated Gene Ontology terms

Biological process: chromatin binding(2012, 2015, 2024) molecular adaptor activity(2022, 2024) translation elongation factor activity(2024) zinc ion binding(2020, 2024) transcription coregulator activity(2020) cysteine-type deubiquitinase activity(2024) chromatin DNA binding(2017) acyltransferase activity, transferring groups other than amino-acyl groups(2024) SNARE binding(2020) RNA polymerase II cis-regulatory region sequence-specific DNA binding(2017)
RNA binding2004

Molecular function: negative regulation of transcription elongation by RNA polymerase II2011, 2012, 2022, 2024 translational elongation2024 regulation of granulocyte differentiation2023, 2024 positive regulation of transcription by RNA polymerase II2015, 2024 positive regulation of protein modification process2015, 2024 fungal-type cell wall organization2019, 2022 regulation of transcription by RNA polymerase II2018 regulation of gene expression2023 protein transport2024 protein deubiquitination2024
negative regulation of transcription by RNA polymerase II2018 intracellular protein transport2024 endoplasmic reticulum to Golgi vesicle-mediated transport2024 cell wall organization2024 COPII-coated vesicle cargo loading2020

Cellular component: NELF complex2011, 2012, 2019, 2022, 2024 nucleus2011, 2019, 2022, 2024 nucleoplasm2013, 2023, 2024 nuclear body2023, 2024 cytosol2023, 2024 membrane2024 fungal-type cell wall2013, 2022, 2024 extracellular region2013, 2024 COPII vesicle coat2023, 2024 transcription repressor complex2004
side of membrane2024 endoplasmic reticulum exit site2020 chromosome2024 cell periphery2018 SAGA complex2020

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8V0Z4C5_CHICK
Ensembl»
0.0
NELFA Negative elongation factor complex member A Gallus gallus
TI:9031 None 		     
E7FFE0_DANRE
ZFIN»
1.3
fi75f03 Negative elongation factor A (Negative
elongation factor complex member A)		 Danio rerio
TI:7955 None
 
F7FPZ3_RAT
RGD»
4.4
Nelfa Negative elongation factor complex member A Rattus norvegicus
TI:10116 None
   
HPF1_YEAST
SGD»
1.3
HPF1 Haze protective factor 1 Saccharomyces cerevisiae
TI:4932 None
 
NELFA_DROME
FlyBase»
2.3
Nelf-A Negative elongation factor A Drosophila melanogaster
TI:7227 None
 
NELFA_HUMAN
Ensembl»
2.9
NELFA Negative elongation factor A (NELF-A)
(Wolf-Hirschhorn syndrome candidate 2 protein)		 Homo sapiens
TI:9606 None
 
NELFA_MOUSE
Ensembl»
1.6
Nelfa Negative elongation factor A (NELF-A)
(Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2)		 Mus musculus
TI:10090 None
 
Q75JP0_DICDI
dictyBase»
0.5
DDB_G0272480 SAP DNA-binding domain-containing protein Dictyostelium discoideum
TI:44689 None