Collated Gene Ontology terms

Biological process: chromatin binding(2012, 2015, 2024) molecular adaptor activity(2022, 2024) translation elongation factor activity(2024) zinc ion binding(2020, 2024) transcription coregulator activity(2020) cysteine-type deubiquitinase activity(2024) chromatin DNA binding(2017) acyltransferase activity, transferring groups other than amino-acyl groups(2024) SNARE binding(2020) RNA polymerase II cis-regulatory region sequence-specific DNA binding(2017)
RNA binding2004

Molecular function: negative regulation of transcription elongation by RNA polymerase II2011, 2012, 2022, 2024 translational elongation2024 regulation of granulocyte differentiation2023, 2024 positive regulation of transcription by RNA polymerase II2015, 2024 positive regulation of protein modification process2015, 2024 fungal-type cell wall organization2019, 2022 regulation of transcription by RNA polymerase II2018 regulation of gene expression2023 protein transport2024 protein deubiquitination2024
negative regulation of transcription by RNA polymerase II2018 intracellular protein transport2024 endoplasmic reticulum to Golgi vesicle-mediated transport2024 cell wall organization2024 COPII-coated vesicle cargo loading2020

Cellular component: NELF complex2011, 2012, 2019, 2022, 2024 nucleus2011, 2019, 2022, 2024 nucleoplasm2013, 2023, 2024 nuclear body2023, 2024 cytosol2023, 2024 membrane2024 fungal-type cell wall2013, 2022, 2024 extracellular region2013, 2024 COPII vesicle coat2023, 2024 transcription repressor complex2004
side of membrane2024 endoplasmic reticulum exit site2020 chromosome2024 cell periphery2018 SAGA complex2020

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
H9GD69_ANOCA
Ensembl»
0.0
NELFA Negative elongation factor complex member A Anolis carolinensis
TI:28377 None
   
A0A453YSQ0_ANOGA
EnsemblMetazoa»
0.0
USP domain-containing protein Anopheles gambiae
TI:7165 None
 
A7UR29_ANOGA
EnsemblMetazoa»
0.0
5667720 AGAP002290-PA Anopheles gambiae
TI:7165 None
 
A6QQS5_BOVIN
Ensembl»
0.0
NELFA Negative elongation factor complex
member A (WHSC2 protein)		 Bos taurus
TI:9913 None
 
A0A9J7HXQ7_BRAFL
CTD»
0.0
LOC118409435 Negative elongation factor A-like Branchiostoma floridae
TI:7739 None
   
A0A8I3NYG9_CANLF
Ensembl»
0.0
NELFA Negative elongation factor complex member A Canis lupus
TI:9612 None
   
A0A2K3CPC5_CHLRE
EnsemblPlants»
0.0
CHLRE_17g707551v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
   
A0A2K3CR61_CHLRE
EnsemblPlants»
0.0
CHLRE_17g733600v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
   
A0A2K3CX12_CHLRE
EnsemblPlants»
0.0
CHLRE_14g608200v5 HTH OST-type domain-containing protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
A0A2K3CZF0_CHLRE
EnsemblPlants»
0.0
CHLRE_13g566500v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
   
A0A2K3D5W4_CHLRE
EnsemblPlants»
0.0
CHLRE_12g555001v5 Protein kinase domain-containing protein Chlamydomonas reinhardtii
TI:3055 None 		 
   
A0A2K3DBE7_CHLRE
EnsemblPlants»
0.0
CHLRE_10g454350v5 Guanylate cyclase domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
   
A0A2K3DEM1_CHLRE
EnsemblPlants»
0.0
CHLRE_09g396289v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
   
A0A2K3DLR1_CHLRE
EnsemblPlants»
0.0
CHLRE_07g357500v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
   
A0A2K3DS81_CHLRE
EnsemblPlants»
0.0
CHLRE_05g245101v5 BTB domain-containing protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
A0A2K3DSK0_CHLRE
EnsemblPlants»
0.0
CHLRE_05g241640v5 CUB domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3DSU9_CHLRE
EnsemblPlants»
0.0
CHLRE_05g236850v5 N-acetyltransferase domain-containing protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
A0A2K3DSV1_CHLRE
EnsemblPlants»
0.0
CHLRE_05g236878v5 N-acetyltransferase domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3DVH7_CHLRE
EnsemblPlants»
0.0
CHLRE_03g146567v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
   
A0A2K3DX41_CHLRE
EnsemblPlants»
0.0
CHLRE_03g171424v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
   
A0A2K3DYQ8_CHLRE
EnsemblPlants»
0.0
CHLRE_03g197450v5 JmjC domain-containing protein Chlamydomonas reinhardtii
TI:3055 None 		 
   
A0A2K3E2E4_CHLRE
EnsemblPlants»
0.0
CHLRE_02g102776v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
   
F6SKY6_CIOIN
Ensembl»
0.0
HDAg domain-containing protein Ciona intestinalis
TI:7719 None
 
E7FFE0_DANRE
ZFIN»
1.3
fi75f03 Negative elongation factor A (Negative
elongation factor complex member A)		 Danio rerio
TI:7955 None
 
E9HUC3_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_304407 HDAg domain-containing protein Daphnia pulex
TI:6669 None
 
Q75JP0_DICDI
dictyBase»
0.5
DDB_G0272480 SAP DNA-binding domain-containing protein Dictyostelium discoideum
TI:44689 None
   
NELFA_DROME
FlyBase»
2.3
Nelf-A Negative elongation factor A Drosophila melanogaster
TI:7227 None
 
A0A337SBY3_FELCA
Ensembl»
0.0
NELFA Negative elongation factor complex member A Felis catus
TI:9685 None
 
A0A8V0Z4C5_CHICK
Ensembl»
0.0
NELFA Negative elongation factor complex member A Gallus gallus
TI:9031 None 		     
G3RE48_GORGO
Ensembl»
0.0
Negative elongation factor complex member A Gorilla gorilla
TI:9593 None
 
T1FUR1_HELRO
EnsemblMetazoa»
0.0
20212557 HDAg domain-containing protein Helobdella robusta
TI:6412 None
 
T1FVC1_HELRO
EnsemblMetazoa»
0.0
20212767 Uncharacterized protein Helobdella robusta
TI:6412 None
   
NELFA_HUMAN
Ensembl»
2.9
NELFA Negative elongation factor A (NELF-A)
(Wolf-Hirschhorn syndrome candidate 2 protein)		 Homo sapiens
TI:9606 None
 
B7PKJ4_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW018991 Negative elongation factor A, putative
(Negative elongation factor A, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
W5M2E1_LEPOC
Ensembl»
0.0
Negative elongation factor complex member A Lepisosteus oculatus
TI:7918 None
 
H9FZF2_MACMU
Ensembl»
0.0
NELFA Negative elongation factor A (Negative
elongation factor complex member A)		 Macaca mulatta
TI:9544 None
 
A0A2R6WUQ4_MARPO
EnsemblPlants»
0.0
MARPO_0056s0035 OVATE domain-containing protein Marchantia polymorpha
TI:3197 None 		 
   
F6VE42_MONDO
Ensembl»
0.0
NELFA Negative elongation factor complex member A Monodelphis domestica
TI:13616 None
   
NELFA_MOUSE
Ensembl»
1.6
Nelfa Negative elongation factor A (NELF-A)
(Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2)		 Mus musculus
TI:10090 None
 
A7T0K3_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g140527 HDAg domain-containing protein Nematostella vectensis
TI:45351 None 		 
 
A7T0K4_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g140529 HDAg domain-containing protein Nematostella vectensis
TI:45351 None 		 
 
A0A6I8P9P6_ORNAN
Ensembl»
0.0
NELFA Negative elongation factor complex member A Ornithorhynchus anatinus
TI:9258 None
   
H2LTZ4_ORYLA
Ensembl»
0.0
nelfa Negative elongation factor complex member A Oryzias latipes
TI:8090 None
   
H2QP42_PANTR
Ensembl»
0.0
NELFA Negative elongation factor complex member
A (Wolf-Hirschhorn syndrome candidate 2)		 Pan troglodytes
TI:9598 None
 
A0BD19_PARTE
EnsemblProtists»
0.0
GSPATT00004530001 Chromosome undetermined scaffold_10,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0C943_PARTE
EnsemblProtists»
0.0
GSPATT00006616001 Chromosome undetermined scaffold_16,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0CDR0_PARTE
EnsemblProtists»
0.0
GSPATT00007139001 Chromosome undetermined scaffold_17,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0CDR1_PARTE
EnsemblProtists»
0.0
GSPATT00007140001 Chromosome undetermined scaffold_17,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0CEJ7_PARTE
EnsemblProtists»
0.0
GSPATT00037652001 Chromosome undetermined scaffold_171,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0CTL6_PARTE
EnsemblProtists»
0.0
GSPATT00010367001 Chromosome undetermined scaffold_27,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0CY68_PARTE
EnsemblProtists»
0.0
GSPATT00039073001 Chromosome undetermined scaffold_303,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0CY69_PARTE
EnsemblProtists»
0.0
GSPATT00039074001 Chromosome undetermined scaffold_303,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
   
A0D468_PARTE
EnsemblProtists»
0.0
GSPATT00013301001 Chromosome undetermined scaffold_37,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0DDS9_PARTE
EnsemblProtists»
0.0
GSPATT00016037001 Chromosome undetermined scaffold_47,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0DG62_PARTE
EnsemblProtists»
0.0
GSPATT00002157001 Chromosome undetermined scaffold_5,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0DPT7_PARTE
EnsemblProtists»
0.0
GSPATT00019236001 Chromosome undetermined scaffold_59,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0DZS5_PARTE
EnsemblProtists»
0.0
GSPATT00021710001 Chromosome undetermined scaffold_70,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0E372_PARTE
EnsemblProtists»
0.0
GSPATT00022912001 Chromosome undetermined scaffold_76,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0E4K0_PARTE
EnsemblProtists»
0.0
GSPATT00023392001 Chromosome undetermined scaffold_78,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0E8P1_PARTE
EnsemblProtists»
0.0
GSPATT00024387001 Chromosome undetermined scaffold_83,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
A0EGP1_PARTE
EnsemblProtists»
0.0
GSPATT00026806001 Chromosome undetermined scaffold_95,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
   
F7FPZ3_RAT
RGD»
4.4
Nelfa Negative elongation factor complex member A Rattus norvegicus
TI:10116 None
   
HPF1_YEAST
SGD»
1.3
HPF1 Haze protective factor 1 Saccharomyces cerevisiae
TI:4932 None
 
A0A7M7SYS6_STRPU
EnsemblMetazoa»
0.0
HDAg domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A5G2QT16_PIG
Ensembl»
0.0
NELFA Negative elongation factor complex member A Sus scrofa
TI:9823 None 		     
B8C308_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_22764 Uncharacterized protein Thalassiosira pseudonana
TI:35128 None
   
D6X2R9_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_12492 Negative elongation factor A-like Protein Tribolium castaneum
TI:7070 None
 
B3SB33_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_61475 HDAg domain-containing protein Trichoplax adhaerens
TI:10228 None
 
A0A1L8HKQ3_XENLA
Xenbase»
0.0
nelfa.S Negative elongation factor A Xenopus laevis
TI:8355 None
   
A0A1L8HT19_XENLA
Xenbase»
0.0
nelfa.L Negative elongation factor A Xenopus laevis
TI:8355 None
   
F6Y7E5_XENTR
Xenbase»
0.0
nelfa Negative elongation factor A (Negative
elongation factor complex member A)		 Xenopus tropicalis
TI:8364 None