Collated Gene Ontology terms

Biological process: lysozyme activity(2005, 2006, 2007, 2017, 2018, 2022, 2024) hydrolase activity, acting on glycosyl bonds(2007, 2024) metal ion binding(2024) lactose synthase activity(2022, 2024) calcium ion binding(2024) identical protein binding(2024) chitinase activity(2006) beta-N-acetylglucosaminidase activity(2011)

Molecular function: defense response to bacterium2004, 2005, 2011, 2017, 2024 fusion of sperm to egg plasma membrane involved in single fertilization2017, 2020, 2024 killing of cells of another organism2017, 2024 defense response to Gram-negative bacterium2007, 2008, 2013, 2017, 2020 defense response to Gram-positive bacterium2007, 2008, 2017, 2020, 2024 fertilization2017, 2024 lactose biosynthetic process2003, 2022, 2024 sperm-egg recognition2006, 2024 single fertilization2024 digestion2024
cell maturation2021 signal transduction2003 response to progesterone2016 response to estradiol2016 response to dehydroepiandrosterone2016 response to 11-deoxycorticosterone2016 positive regulation of phagocytosis2006 positive regulation of macrophage activation2006 negative regulation of innate immune response2013 monocyte activation2006 inflammatory response2006 cell-cell signaling2003 cell wall macromolecule catabolic process2016 apoptotic process2003 antimicrobial humoral response2024

Cellular component: acrosomal vesicle2006, 2017, 2020, 2024 sperm flagellum2017, 2020, 2024 extracellular space2003, 2006, 2010, 2011, 2014, 2015, 2017, 2024 extracellular region2016, 2024 acrosomal membrane2017, 2024 secretory granule2006, 2007, 2024 sperm plasma membrane2017, 2024 acrosomal matrix2017, 2024 protein-containing complex2022, 2024 sperm midpiece2017, 2024
motile cilium2024 cytoplasmic vesicle2024 membrane2024 cell surface2024 trans-Golgi network transport vesicle2007 tertiary granule lumen2016 specific granule lumen2016 rough endoplasmic reticulum lumen2007 nucleus2014 microvillus2007 extracellular exosome2014 endoplasmic reticulum lumen2007 endoplasmic reticulum2011 cytoplasm2016 azurophil granule lumen2016 Golgi stack2007 Golgi membrane2014 Golgi lumen2014 Golgi cis cisterna2007

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 0/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.


Proteins

UniProt ID
Organism DB»
Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q54XV8_DICDI
dictyBase»
0.5
DDB_G0278563 Transglycosylase SLT domain-containing protein Dictyostelium discoideum
TI:44689 None
 
A1ZBX7_DROME
FlyBase»
1.5
Dmel\CG11159 GEO12014p1 Drosophila melanogaster
TI:7227 None
 
Q9W4C2_DROME
FlyBase»
1.5
Dmel\CG16756 GEO08277p1 (RH17440p) Drosophila melanogaster
TI:7227 None
 
A1ZBX6_DROME
FlyBase»
1.5
Dmel\CG16799 Uncharacterized protein, isoform A (Uncharacterized
protein, isoform B (EC 3.2.1.17))
Drosophila melanogaster
TI:7227 None
 
A1Z9D5_DROME
FlyBase»
1.5
Dmel\CG30062 IP06881p Drosophila melanogaster
TI:7227 None
 
A1ZAB8_DROME
FlyBase»
1.5
Dmel\CG7798 GEO02684p1 (MIP31483p) Drosophila melanogaster
TI:7227 None
 
Q9VSA5_DROME
FlyBase»
1.5
Dmel\CG8492 Glycosyl hydrolases family
22 (GH22) domain-containing protein
Drosophila melanogaster
TI:7227 None
 
LALBA_HUMAN
Ensembl»
5.0
LALBA Alpha-lactalbumin (Lactose synthase B
protein) (Lysozyme-like protein 7)
Homo sapiens
TI:9606 None
 
A0A8M6Z596_DANRE
CTD»
0.0
LOC100536618 Sperm acrosome-associated protein 5-like Danio rerio
TI:7955 None
   
A0A8M1RN62_DANRE
CTD»
0.0
LOC100536671 Vegetative cell wall protein gp1-like Danio rerio
TI:7955 None
     
A0A8M1RTP2_DANRE
CTD»
0.0
LOC100536887 Uncharacterized protein LOC100536887 Danio rerio
TI:7955 None
     
LYSC_CHICK
Ensembl»
5.6
LYZ Lysozyme C (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase C) (Allergen
Gal d IV) (allergen Gal d 4)
Gallus gallus
TI:9031 None
 
LYSC_HUMAN
Ensembl»
7.4
LYZ Lysozyme C (EC
3.2.1.17) (1,4-beta-N-acetylmuramidase C)
Homo sapiens
TI:9606 None
 
LYZL1_HUMAN
Ensembl»
0.5
LYZL1 Lysozyme-like protein 1 (EC 3.2.1.17) Homo sapiens
TI:9606 None
 
LYZL2_HUMAN
Ensembl»
0.5
LYZL2 Lysozyme-like protein 2
(Lysozyme-2) (EC 3.2.1.17)
Homo sapiens
TI:9606 None
 
LYZL4_HUMAN
Ensembl»
1.5
LYZL4 Lysozyme-like protein 4 (Lysozyme-4) Homo sapiens
TI:9606 None
 
LYZL6_HUMAN
Ensembl»
3.4
LYZL6 Lysozyme-like protein 6 (EC 3.2.1.17) Homo sapiens
TI:9606 None
 
LALBA_MOUSE
Ensembl»
1.6
Lalba Alpha-lactalbumin (Lactose synthase B protein) Mus musculus
TI:10090 None
 
LALBA_RAT
RGD»
1.5
Lalba Alpha-lactalbumin (Lactose synthase B protein) Rattus norvegicus
TI:10116 None
 
A0A8I5Y928_RAT
RGD»
1.5
Lyc2 Lysozyme C type 2 Rattus norvegicus
TI:10116 None
   
LYSB_DROME
FlyBase»
1.5
LysB Lysozyme B (EC
3.2.1.17) (1,4-beta-N-acetylmuramidase B)
Drosophila melanogaster
TI:7227 None
 
LYSD_DROME
FlyBase»
2.6
LysD Lysozyme D (EC
3.2.1.17) (1,4-beta-N-acetylmuramidase D)
Drosophila melanogaster
TI:7227 None
 
LYSE_DROME
FlyBase»
2.5
LysE Lysozyme E (EC
3.2.1.17) (1,4-beta-N-acetylmuramidase E)
Drosophila melanogaster
TI:7227 None
 
LYSP_DROME
FlyBase»
1.5
LysP Lysozyme P (EC
3.2.1.17) (1,4-beta-N-acetylmuramidase P)
Drosophila melanogaster
TI:7227 None
 
LYSS_DROME
FlyBase»
1.5
LysS Lysozyme S (EC
3.2.1.17) (1,4-beta-N-acetylmuramidase S)
Drosophila melanogaster
TI:7227 None
 
LYSX_DROME
FlyBase»
1.5
LysX Lysozyme X (EC
3.2.1.17) (1,4-beta-N-acetylmuramidase X)
Drosophila melanogaster
TI:7227 None
 
LYSC1_RAT
RGD»
8.0
Lyz1 Lysozyme C-1 (EC
3.2.1.17) (1,4-beta-N-acetylmuramidase C)
Rattus norvegicus
TI:10116 None
 
LYZ1_MOUSE
Ensembl»
1.6
Lyz1 Lysozyme C-1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase
C) (Lysozyme C type P)
Mus musculus
TI:10090 None
 
LYSC2_RAT
AG»
1.5
Lyz2 Putative lysozyme C-2
(EC 3.2.1.17) (1,4-beta-N-acetylmuramidase C)
Rattus norvegicus
TI:10116 None
 
LYZ2_MOUSE
Ensembl»
3.2
Lyz2 Lysozyme C-2 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase
C) (Lysozyme C type M)
Mus musculus
TI:10090 None
 
Q8BM26_MOUSE
Ensembl»
0.0
Lyz3 9530003J23Rik protein (Lysozyme f1)
(RIKEN cDNA 9530003J23 gene)
Mus musculus
TI:10090 None
 
D4A0W0_RAT
RGD»
0.5
Lyzl1 Lysozyme d1 (Lysozyme-like 1) Rattus norvegicus
TI:10116 None
 
LYZL1_MOUSE
Ensembl»
0.0
Lyzl1 Lysozyme-like protein 1 (EC 3.2.1.17) Mus musculus
TI:10090 None
 
LYZL4_MOUSE
Ensembl»
1.6
Lyzl4 Lysozyme-like protein 4 (Lysozyme-4) Mus musculus
TI:10090 None
 
LYZL4_RAT
RGD»
4.1
Lyzl4 Lysozyme-like protein 4 (Lysozyme-4) Rattus norvegicus
TI:10116 None
 
A0A077S6M4_RAT
RGD»
2.5
Lyzl6 Lysozyme-like 6 Rattus norvegicus
TI:10116 None
   
LYZL6_MOUSE
Ensembl»
1.5
Lyzl6 Lysozyme-like protein 6 (EC 3.2.1.17) Mus musculus
TI:10090 None
 
D4A0W2_RAT
RGD»
1.5
RGD1306474 Lysozyme f1 (Similar to RIKEN cDNA 9530003J23) Rattus norvegicus
TI:10116 None
 
SACA3_HUMAN
Ensembl»
4.8
SPACA3 Sperm acrosome membrane-associated protein 3 (Cancer/testis antigen 54) (CT54) (Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17) (Lysozyme-like protein 3) (Sperm lysozyme-like protein 1) (Sperm protein
reactive with antisperm antibodies) (Sperm protein reactive with ASA) [Cleaved into: Sperm acrosome membrane-associated protein 3, membrane form; Sperm acrosome membrane-associated protein 3, processed form]
Homo sapiens
TI:9606 None
 
LYZL5_HUMAN
Ensembl»
1.0
SPACA5; SPACA5B Sperm acrosome-associated protein 5 (EC 3.2.1.17) (Lysozyme-like
protein 5) (Sperm-specific lysozyme-like protein X) (SLLP-X)
Homo sapiens
TI:9606 None
 
F1M6E7_RAT
RGD»
2.0
Spaca3 Lysozyme c (Sperm acrosome associated 3) Rattus norvegicus
TI:10116 None
 
SACA3_MOUSE
Ensembl»
1.6
Spaca3 Sperm acrosome membrane-associated protein 3 (Lysozyme-like protein 3) (Sperm lysozyme-like protein 1) (mSLLP1) [Cleaved
into: Sperm acrosome membrane-associated protein 3, membrane form; Sperm acrosome membrane-associated protein 3, processed form]
Mus musculus
TI:10090 None
 
LYZL5_MOUSE
Ensembl»
0.0
Spaca5 Sperm acrosome-associated protein 5
(EC 3.2.1.17) (Lysozyme-like protein 5)
Mus musculus
TI:10090 None
 
M0RCC1_RAT
RGD»
1.0
Spaca5 Sperm acrosome associated 5 Rattus norvegicus
TI:10116 None
   
Y1137_DICDI
dictyBase»
0.5
lyC2 Lysozyme C-like protein DDB_G0291137 Dictyostelium discoideum
TI:44689 None
 
Q90YS5_DANRE
ZFIN»
2.2
lys-C Lysozyme C (Lysozyme-like protein
2 precursor (EC 3.2.1.17))
Danio rerio
TI:7955 None
 
Q8MML4_DICDI
dictyBase»
0.5
rcdBB HypotPutative Glycosidase (Random
cDNA clone veg113)
Dictyostelium discoideum
TI:44689 None
 
A0A8M9QGP2_DANRE
CTD»
0.0
wu:fj19g03 Uncharacterized protein wu:fj19g03 Danio rerio
TI:7955 None