Collated Gene Ontology terms

Biological process:

Molecular function: non-motile cilium assembly2016, 2017, 2025 cell projection organization2025 cilium assembly2012, 2015, 2016, 2025 smoothened signaling pathway2012, 2025 positive regulation of smoothened signaling pathway2025 positive regulation of cilium assembly2025 photoreceptor cell morphogenesis2025 photoreceptor cell maintenance2025 protein localization to ciliary transition zone2016, 2025 photoreceptor cell outer segment organization2023
convergent extension involved in gastrulation2012

Cellular component: ciliary transition zone2011, 2012, 2016, 2017, 2025 membrane2012, 2025 cilium2012, 2015, 2025 MKS complex2012, 2025 ciliary membrane2012, 2025 mitochondrion2014 cytosol2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 3/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A5F8HCY2_MONDO
Ensembl»
0.0
Transmembrane protein 216 Monodelphis domestica
TI:13616 None
   
A0A7M7P831_STRPU
EnsemblMetazoa»
0.0
Transmembrane protein 216 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7P9V8_STRPU
EnsemblMetazoa»
0.0
Transmembrane protein 17 Strongylocentrotus purpuratus
TI:7668 None
   
A0A9L0TIS8_HORSE
Ensembl»
0.0
Transmembrane protein 80 Equus caballus
TI:9796 None
   
A0ABI7W6H1_FELCA
Ensembl»
0.0
Transmembrane protein 80 Felis catus
TI:9685 None
   
A0ABK8G7Q3_ANOGA
EnsemblMetazoa»
0.0
Transmembrane protein 17 Anopheles gambiae
TI:7165 None
 
F7FJZ3_MONDO
Ensembl»
0.0
Transmembrane protein 216 Monodelphis domestica
TI:13616 None
   
F7FJZ5_MONDO
Ensembl»
0.0
Transmembrane protein 216 Monodelphis domestica
TI:13616 None
   
G3RDS3_GORGO
Ensembl»
0.0
Transmembrane protein 80 Gorilla gorilla
TI:9593 None
 
W5LWB6_LEPOC
Ensembl»
0.0
Transmembrane protein 216 Lepisosteus oculatus
TI:7918 None
   
W5M7L8_LEPOC
Ensembl»
0.0
Zgc:112294 Lepisosteus oculatus
TI:7918 None
 
W5MM70_LEPOC
Ensembl»
0.0
Transmembrane protein 17 Lepisosteus oculatus
TI:7918 None
 
Q7PS73_ANOGA
EnsemblMetazoa»
0.0
1271534 AGAP003795-PA Anopheles gambiae
TI:7165 None
 
T1FX93_HELRO
EnsemblMetazoa»
0.0
20213441 Uncharacterized protein Helobdella robusta
TI:6412 None
 
T1G6W2_HELRO
EnsemblMetazoa»
0.0
20216809 Transmembrane protein 17 Helobdella robusta
TI:6412 None
 
D6X4X1_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_11020 Transmembrane protein 216-like Protein Tribolium castaneum
TI:7070 None
 
A0A139WC55_TRICA
neXtProt»
0.0
AUGUSTUS-3.0.2_31228 Transmembrane protein 17-like Protein Tribolium castaneum
TI:7070 None
 
F4P2Q5_BATDJ
euHCVdb»
0.0
BATDEDRAFT_88744 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None
 
A8WTY7_CAEBR
WormBase»
0.0
CBG02597 CBG_02597 Protein CBG02597 Caenorhabditis briggsae
TI:6238 None
 
A0A2K3DHZ6_CHLRE
euHCVdb»
0.0
CHLRE_08g379750v5 Transmembrane protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3DA64_CHLRE
neXtProt»
0.0
CHLRE_10g435600v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
E9G4T7_DAPPU
neXtProt»
0.0
DAPPUDRAFT_300429 Transmembrane protein 17 Daphnia pulex
TI:6669 None
 
Q8INQ3_DROME
FlyBase»
1.0
Dmel\CG11760 GEO13292p1 (RE66485p) Drosophila melanogaster
TI:7227 None
 
A0CY07_PARTE
euHCVdb»
0.0
GSPATT00011306001 Transmembrane protein Paramecium tetraurelia
TI:5888 None
 
A0D568_PARTE
euHCVdb»
0.0
GSPATT00013632001 Transmembrane protein Paramecium tetraurelia
TI:5888 None
 
A0DHL5_PARTE
euHCVdb»
0.0
GSPATT00016919001 Transmembrane protein Paramecium tetraurelia
TI:5888 None
 
B7QIP3_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW014288 Transmembrane protein, putative Ixodes scapularis
TI:6945 None
 
A0A1Y1I6X5_KLENI
euHCVdb»
0.0
KFL_003060040 Transmembrane protein Klebsormidium nitens
TI:105231 None
 
A0A1Y1IPP0_KLENI
euHCVdb»
0.0
KFL_007390050 Transmembrane protein Klebsormidium nitens
TI:105231 None
 
Q4Q3D6_LEIMA
TubercuList»
0.0
LMJF_34_0705 Transmembrane protein Leishmania major
TI:5664 None
 
F7B9H1_CIOIN
Ensembl»
0.0
LOC100183084 Transmembrane protein 17B-like Ciona intestinalis
TI:7719 None
   
H2XWL2_CIOIN
Ensembl»
0.0
LOC100186699 Transmembrane protein 216-like Ciona intestinalis
TI:7719 None
 
A0A803T6R9_ANOCA
Ensembl»
0.0
LOC100555365 Transmembrane protein 17B Anolis carolinensis
TI:28377 None
   
A0A8V0X593_CHICK
Ensembl»
0.5
LOC100858995 Transmembrane protein 17B Gallus gallus
TI:9031 None
   
A0A1L8I1M8_XENLA
CTD»
0.0
LOC108717233 Transmembrane protein 17B Xenopus laevis
TI:8355 None
   
A0A9J7HRW1_BRAFL
euHCVdb»
0.0
LOC118406735 Transmembrane protein 216-like Branchiostoma floridae
TI:7739 None
   
C3YCS9_BRAFL
neXtProt»
0.0
LOC118426554 Transmembrane protein 17B-like Branchiostoma floridae
TI:7739 None
 
A9UQC2_MONBE
euHCVdb»
0.0
MONBRDRAFT_5230 Uncharacterized protein Monosiga brevicollis
TI:81824 None
 
A7SAJ8_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g111004 Transmembrane protein 17 Nematostella vectensis
TI:45351 None
 
A7SXC1_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g175269 Transmembrane protein 216 Nematostella vectensis
TI:45351 None
 
A0A6I8N563_ORNAN
Ensembl»
0.0
TMEM138 Transmembrane protein 216 Ornithorhynchus anatinus
TI:9258 None
   
A0A3Q2H7T0_HORSE
Ensembl»
0.0
TMEM17 Transmembrane protein 17 Equus caballus
TI:9796 None
   
A0A8I3P2T5_CANLF
Ensembl»
0.0
TMEM17 Transmembrane protein 17 Canis lupus
TI:9612 None
   
A0A8V0Z1W0_CHICK
Ensembl»
0.5
TMEM17 Transmembrane protein 17 Gallus gallus
TI:9031 None
   
A0ABI7VR70_FELCA
Ensembl»
0.0
TMEM17 Transmembrane protein 17 Felis catus
TI:9685 None
   
F6PQE0_MONDO
Ensembl»
0.0
TMEM17 Transmembrane protein 17 Monodelphis domestica
TI:13616 None
   
F7DKD3_ORNAN
Ensembl»
0.0
TMEM17 Transmembrane protein 17 Ornithorhynchus anatinus
TI:9258 None
   
G7NA58_MACMU
Ensembl»
0.0
TMEM17 Transmembrane protein 17 Macaca mulatta
TI:9544 None
 
H2MPJ7_ORYLA
Ensembl»
0.0
TMEM17 Transmembrane protein 17 Oryzias latipes
TI:8090 None
   
H2QHZ1_PANTR
Ensembl»
0.0
TMEM17 Transmembrane protein 17 Pan troglodytes
TI:9598 None
 
I3LBE3_PIG
Ensembl»
0.0
TMEM17 Transmembrane protein 17 Sus scrofa
TI:9823 None
 
TMM17_BOVIN
Ensembl»
0.0
TMEM17 Transmembrane protein 17 Bos taurus
TI:9913 None
 
TMM17_CHICK
CTD»
1.5
TMEM17 Transmembrane protein 17 Gallus gallus
TI:9031 None
 
TMM17_HUMAN
Ensembl»
2.9
TMEM17 Transmembrane protein 17 Homo sapiens
TI:9606 None
 
A0A1D5PGJ8_CHICK
Ensembl»
0.0
TMEM216 Transmembrane protein 216 Gallus gallus
TI:9031 None
   
A0A287AG87_PIG
Ensembl»
0.0
TMEM216 Transmembrane protein 216 Sus scrofa
TI:9823 None
 
A0A5F5PY18_HORSE
Ensembl»
0.0
TMEM216 Transmembrane protein 216 Equus caballus
TI:9796 None
   
A0A8I3RZL1_CANLF
Ensembl»
0.0
TMEM216 Transmembrane protein 216 Canis lupus
TI:9612 None
   
A0AAA9TRK5_BOVIN
Ensembl»
0.0
TMEM216 Transmembrane protein 216 Bos taurus
TI:9913 None
   
F7C005_MACMU
Ensembl»
0.0
TMEM216 Transmembrane protein 216 Macaca mulatta
TI:9544 None
   
G3RZ04_GORGO
Ensembl»
0.0
TMEM216 Transmembrane protein 216 Gorilla gorilla
TI:9593 None
 
H2M7P7_ORYLA
Ensembl»
0.0
TMEM216 Transmembrane protein 216 Oryzias latipes
TI:8090 None
   
H2RCE3_PANTR
Ensembl»
0.0
TMEM216 Transmembrane protein 216 Pan troglodytes
TI:9598 None
 
Q9VHN0_DROME
FlyBase»
1.0
TMEM216 GEO07735p1 (RE40776p) (Transmembrane protein 216, isoform A) (Transmembrane
protein 216, isoform B) (Transmembrane protein 216, isoform C)		 Drosophila melanogaster
TI:7227 None
 
TM216_BOVIN
CTD»
0.0
TMEM216 Transmembrane protein 216 Bos taurus
TI:9913 None
 
TM216_HUMAN
Ensembl»
3.9
TMEM216 Transmembrane protein 216 Homo sapiens
TI:9606 None
 
A0A3B3H617_ORYLA
Ensembl»
0.0
TMEM80 Transmembrane protein 80 Oryzias latipes
TI:8090 None
   
A0A5F8A182_MACMU
Ensembl»
0.0
TMEM80 Transmembrane protein 80 Macaca mulatta
TI:9544 None
   
A0A8I3P4X2_CANLF
Ensembl»
0.0
TMEM80 Transmembrane protein 80 Canis lupus
TI:9612 None
   
A0A8V0ZP69_CHICK
Ensembl»
0.5
TMEM80 Transmembrane protein 80 Gallus gallus
TI:9031 None
   
A0A8W4FL01_PIG
Ensembl»
0.0
TMEM80 Transmembrane protein 80 Sus scrofa
TI:9823 None
   
G1KQQ5_ANOCA
Ensembl»
0.0
TMEM80 Transmembrane protein 80 Anolis carolinensis
TI:28377 None
   
H2Q2V6_PANTR
Ensembl»
0.0
TMEM80 Transmembrane protein 80 Pan troglodytes
TI:9598 None
 
TMM80_BOVIN
Ensembl»
0.0
TMEM80 Transmembrane protein 80 Bos taurus
TI:9913 None
 
TMM80_HUMAN
Ensembl»
0.5
TMEM80 Transmembrane protein 80 Homo sapiens
TI:9606 None
 
A2G3U7_TRIV3
TubercuList»
0.0
TVAG_041330 Transmembrane protein Trichomonas vaginalis
TI:5722 None
 
A2DLQ7_TRIV3
TubercuList»
0.0
TVAG_062950 Transmembrane protein Trichomonas vaginalis
TI:5722 None
 
Q585H9_TRYB2
TubercuList»
0.0
Tb04.26G5.630 Transmembrane protein Trypanosoma brucei
TI:5691 None
 
Q389Y2_TRYB2
TubercuList»
0.0
Tb10.6k15.0340 Uncharacterized protein Trypanosoma brucei
TI:5691 None
 
TMM17_MOUSE
Ensembl»
2.6
Tmem17 Transmembrane protein 17 Mus musculus
TI:10090 None
 
TMM17_RAT
RGD»
3.0
Tmem17 Transmembrane protein 17 Rattus norvegicus
TI:10116 None
 
TM17B_XENTR
Xenbase»
0.0
Tmem17-b Transmembrane protein 17B Xenopus tropicalis
TI:8364 None
 
TM17B_DANRE
ZFIN»
1.5
Tmem17b Transmembrane protein 17B Danio rerio
TI:7955 None
 
TM216_MOUSE
Ensembl»
4.9
Tmem216 Transmembrane protein 216
(Thymus atrophy-related protein)		 Mus musculus
TI:10090 None
 
TM216_RAT
RGD»
4.5
Tmem216 Transmembrane protein 216 Rattus norvegicus
TI:10116 None
 
A0A8I6AG20_RAT
RGD»
0.0
Tmem80 Transmembrane protein 80 Rattus norvegicus
TI:10116 None
   
TMM80_MOUSE
Ensembl»
0.5
Tmem80 Transmembrane protein 80 Mus musculus
TI:10090 None
 
A0A2A6BA87_PRIPA
EnsemblMetazoa»
0.0
WBGene00104842 Uncharacterized protein Pristionchus pacificus
TI:54126 None
   
A0A2A6CZ46_PRIPA
EnsemblMetazoa»
0.0
WBGene00106668 Major sperm protein Pristionchus pacificus
TI:54126 None
   
C8JQP7_CAEEL
WormBase»
2.9
mks-2 MecKel-Gruber Syndrome (MKS) homolog Caenorhabditis elegans
TI:6239 None
 
A8XPD6_CAEBR
WormBase»
0.0
tmem-17 Protein CBG16514 Caenorhabditis briggsae
TI:6238 None
 
Q23481_CAEEL
WormBase»
0.5
tmem-17 TMEM (Human TransMEMbrane protein) homolog Caenorhabditis elegans
TI:6239 None
 
A0A803TDG5_ANOCA
Ensembl»
0.0
tmem17 Transmembrane protein 17 Anolis carolinensis
TI:28377 None
   
A0ABD8GG26_XENTR
Xenbase»
0.0
tmem17 Transmembrane protein 17B Xenopus tropicalis
TI:8364 None
   
TM17A_XENTR
Xenbase»
0.0
tmem17-a Transmembrane protein 17A Xenopus tropicalis
TI:8364 None
 
TM17A_DANRE
ZFIN»
1.5
tmem17a Transmembrane protein 17A Danio rerio
TI:7955 None
 
A0A1L8GFM4_XENLA
Xenbase»
0.0
tmem17l.S Transmembrane protein 17A Xenopus laevis
TI:8355 None
   
A0A8J1J5Z0_XENTR
Xenbase»
0.0
tmem216 Transmembrane protein 216 Xenopus tropicalis
TI:8364 None
   
TM216_DANRE
ZFIN»
5.5
tmem216 Transmembrane protein 216 Danio rerio
TI:7955 None
 
A0A8J1MAE5_XENLA
CTD»
0.0
tmem216.L Transmembrane protein 216 Xenopus laevis
TI:8355 None
   
A0A6I8RIV0_XENTR
Xenbase»
0.0
tmem80 Transmembrane protein 80 Xenopus tropicalis
TI:8364 None
   
A0A1L8GJJ4_XENLA
Xenbase»
0.0
tmem80.L Transmembrane protein 80 Xenopus laevis
TI:8355 None
   
H2L5G6_ORYLA
Ensembl»
0.0
zgc:112294 Zgc:112294 Oryzias latipes
TI:8090 None