Collated Gene Ontology terms

Biological process: protein transmembrane transporter activity(2008, 2018, 2024, 2025) mitochondrion targeting sequence binding(2023, 2025) ATP hydrolysis activity(2023)

Molecular function: protein import into mitochondrial matrix2004, 2013, 2020, 2025 protein transport2025 intracellular protein transport2025 protein insertion into mitochondrial outer membrane2013, 2020, 2024, 2025 protein targeting to mitochondrion2007, 2019, 2023, 2025 protein insertion into mitochondrial membrane2017, 2025 positive regulation of apoptotic process2017, 2025 liver development2010

Cellular component: mitochondrial outer membrane translocase complex2008, 2013, 2017, 2020, 2023, 2025 mitochondrial outer membrane2011, 2013, 2018, 2023, 2024, 2025 mitochondrion2009, 2018, 2024, 2025 membrane2012, 2014, 2025 plasma membrane2014 mitochondrial inner membrane2005 TOM complex2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A2I2YQQ4_GORGO
Ensembl»
0.0
Uncharacterized protein Gorilla gorilla
TI:9593 None
 
A0A2I2YW56_GORGO
Ensembl»
0.0
Uncharacterized protein Gorilla gorilla
TI:9593 None
 
A0A2I3TJJ1_PANTR
Ensembl»
0.0
Uncharacterized protein Pan troglodytes
TI:9598 None
 
A0A2I3TN95_PANTR
Ensembl»
0.0
Uncharacterized protein Pan troglodytes
TI:9598 None
 
A0A3B3I7U3_ORYLA
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Oryzias latipes
TI:8090 None
   
A0A3Q2LEX1_HORSE
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Equus caballus
TI:9796 None
   
A0A5F8H0G4_MONDO
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Monodelphis domestica
TI:13616 None
   
A0A7M7PUI7_STRPU
EnsemblMetazoa»
0.0
Mitochondrial import receptor
subunit TOM22 homolog		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7RGY3_STRPU
EnsemblMetazoa»
0.0
Mitochondrial import receptor
subunit TOM22 homolog		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7U2I8I1_PHANO
TubercuList»
0.0
JI435_106020 Mitochondrial import receptor subunit tom22 Phaeosphaeria nodorum
TI:13684 None
 
A0A803TRL9_ANOCA
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Anolis carolinensis
TI:28377 None
   
A0A8I3PRQ6_CANLF
Ensembl»
0.0
LOC100855486 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Canis lupus
TI:9612 None
   
A0A8I3S5W1_CANLF
Ensembl»
0.0
Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Canis lupus
TI:9612 None
   
A0A8I3S6N9_CANLF
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Canis lupus
TI:9612 None
   
A0A8J0V887_XENLA
CTD»
0.0
LOC108715774 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Xenopus laevis
TI:8355 None
   
A0A8V0YNP8_CHICK
Ensembl»
1.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Gallus gallus
TI:9031 None
   
A0A9J7N7E1_BRAFL
euHCVdb»
0.0
LOC118429521 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Branchiostoma floridae
TI:7739 None
   
A0ABI7YIF1_FELCA
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Felis catus
TI:9685 None
   
A7E4R0_SCLS1
TubercuList»
0.0
SS1G_00282 Mitochondrial import receptor subunit tom22 Sclerotinia sclerotiorum
TI:5180 None
 
A7SPU1_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g126388 Mitochondrial import receptor
subunit TOM22 homolog		 Nematostella vectensis
TI:45351 None
 
A8X3S5_CAEBR
WormBase»
0.0
tomm-22 Mitochondrial import receptor
subunit TOM22 homolog		 Caenorhabditis briggsae
TI:6238 None
 
A9V1G1_MONBE
neXtProt»
0.0
MONBRDRAFT_32747 Mitochondrial import receptor
subunit TOM22 homolog		 Monosiga brevicollis
TI:81824 None
 
B3RN60_TRIAD
CTD»
0.0
TRIADDRAFT_53049 Mitochondrial import receptor
subunit TOM22 homolog		 Trichoplax adhaerens
TI:10228 None
 
B6K462_SCHJY
TubercuList»
0.0
tom22 TOM complex subunit Tom22 Schizosaccharomyces japonicus
TI:4897 None
 
D6X290_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_12425 Mitochondrial import receptor
subunit TOM22 homolog		 Tribolium castaneum
TI:7070 None
 
E3KQD4_PUCGT
TubercuList»
0.0
PGTG_12465 Mitochondrial import receptor protein Puccinia graminis
TI:5297 None
 
E9HF14_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_62022 Mitochondrial import receptor
subunit TOM22 homolog		 Daphnia pulex
TI:6669 None
 
F1SLC2_PIG
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Sus scrofa
TI:9823 None
   
F4NZN9_BATDJ
euHCVdb»
0.0
BATDEDRAFT_24020 Mitochondrial import receptor subunit Tom22 Batrachochytrium dendrobatidis
TI:109871 None
 
F6QTZ2_MONDO
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Monodelphis domestica
TI:13616 None
   
F6T9W8_ORNAN
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Ornithorhynchus anatinus
TI:9258 None
   
F6YG80_MACMU
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Macaca mulatta
TI:9544 None
 
G3RBP4_GORGO
Ensembl»
0.0
CBY1 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Gorilla gorilla
TI:9593 None
 
H2QLN9_PANTR
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Pan troglodytes
TI:9598 None
 
H2XY09_CIOIN
Ensembl»
0.0
Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Ciona intestinalis
TI:7719 None
 
Q28BJ9_XENTR
Xenbase»
0.0
tomm22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Xenopus tropicalis
TI:8364 None
 
Q4WSR8_ASPFU
TubercuList»
0.0
AFUA_1G11860 Mitochondrial import receptor subunit tom22 Aspergillus fumigatus
TI:746128 None
 
Q59LZ9_CANAL
CGD»
0.0
TOM22 Tom22p Candida albicans
TI:5476 None
 
Q5BEC5_EMENI
TubercuList»
0.0
ANIA_01105 Mitochondrial import receptor
subunit tom22 (AFU_orthologue AFUA_1G11860)		 Emericella nidulans
TI:162425 None
 
Q5KA77_CRYD1
TubercuList»
0.0
CNJ02690 Mitochondrial import receptor
subunit tom22, putative		 Cryptococcus deneoformans
TI:40410 None
 
Q5PQ17_XENLA
Xenbase»
0.0
tomm22.L Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Xenopus laevis
TI:8355 None
 
Q6CCA8_YARLI
TubercuList»
0.0
YALI0_C11011g YALI0C11011p Yarrowia lipolytica
TI:4952 None
 
Q6IQJ1_DANRE
ZFIN»
1.8
tomm22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Danio rerio
TI:7955 None
 
Q74Z61_EREGS
euHCVdb»
0.0
AGOS_AGR345C AGR345Cp Eremothecium gossypii
TI:33169 None
 
Q7Q7D3_ANOGA
EnsemblMetazoa»
0.0
1276077 Mitochondrial import receptor
subunit TOM22 homolog		 Anopheles gambiae
TI:7165 None
 
Q9VZL1_DROME
FlyBase»
5.6
mge Mitochondrial import receptor
subunit TOM22 homolog		 Drosophila melanogaster
TI:7227 None
 
T1G490_HELRO
EnsemblMetazoa»
0.0
20215888 Mitochondrial import receptor
subunit TOM22 homolog		 Helobdella robusta
TI:6412 None
 
TOM22_BOVIN
Ensembl»
0.0
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Bos taurus
TI:9913 None
 
TOM22_CAEEL
WormBase»
1.0
tomm-22 Mitochondrial import receptor
subunit TOM22 homolog		 Caenorhabditis elegans
TI:6239 None
 
TOM22_HUMAN
Ensembl»
5.5
TOMM22 Mitochondrial import receptor subunit TOM22 homolog (hTom22) (1C9-2)
(Translocase of outer membrane 22 kDa subunit homolog)		 Homo sapiens
TI:9606 None
 
TOM22_MOUSE
Ensembl»
4.5
Tomm22 Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Mus musculus
TI:10090 None
 
TOM22_NEUCR
EnsemblFungi»
0.0
tom22 Mitochondrial import receptor subunit tom22 (MOM22 protein) (Mitochondrial 22 kDa
outer membrane protein) (Translocase of outer membrane 22 kDa subunit)		 Neurospora crassa
TI:5141 None
 
TOM22_RAT
RGD»
4.7
Tomm22 Mitochondrial import receptor subunit TOM22 homolog (rTOM22)
(Translocase of outer membrane 22 kDa subunit homolog)		 Rattus norvegicus
TI:10116 None
 
TOM22_SCHPO
PomBase»
2.5
tom22 Mitochondrial import receptor subunit tom22 (Mitochondrial 22 kDa outer
membrane protein) (Translocase of outer membrane 22 kDa subunit)		 Schizosaccharomyces pombe
TI:4896 None
 
TOM22_YEAST
SGD»
4.8
TOM22 Mitochondrial import receptor subunit TOM22 (Mitochondrial 17 kDa assembly protein) (Mitochondrial 22
kDa outer membrane protein) (Protein MAS17) (Translocase of outer membrane 22 kDa subunit)		 Saccharomyces cerevisiae
TI:4932 None
 
W5N1G9_LEPOC
Ensembl»
0.0
Mitochondrial import receptor subunit TOM22 homolog (Translocase
of outer membrane 22 kDa subunit homolog)		 Lepisosteus oculatus
TI:7918 None