Biological process: GTP binding^{(2005, 2006, 2009, 2014, 2017, 2023, 2024)} GTPase activity^{(2004, 2014, 2015, 2016, 2017, 2023, 2024)} protein heterodimerization activity^{(2006, 2009, 2012, 2024)} GTPase binding^{(2017, 2024)} protein-membrane adaptor activity^{(2023, 2024)} GDP binding^{(2017, 2023, 2024)} molecular adaptor activity^{(2023, 2024)} hydrolase activity⁽²⁰²⁴⁾ guanyl ribonucleotide binding^{(2013, 2024)} enzyme-substrate adaptor activity^{(2023, 2024)}
± 9 protein homodimerization activity^{2006, 2024} phosphoprotein binding^{2006, 2009, 2024} ubiquitin protein ligase binding^{2015, 2024} identical protein binding²⁰²⁴ protein serine/threonine kinase activator activity²⁰²³ protein kinase activity²⁰²⁴ metal ion binding²⁰²⁴ magnesium ion binding²⁰⁰³ ATP binding²⁰²⁴

Molecular function: positive regulation of TORC1 signaling^{2015, 2017, 2020, 2021, 2023, 2024} negative regulation of autophagy^{2015, 2019, 2023, 2024} cellular response to starvation^{2012, 2023, 2024} cellular response to amino acid stimulus^{2010, 2017, 2021, 2024} positive regulation of TOR signaling^{2010, 2011, 2012, 2013, 2020, 2023, 2024} cellular response to amino acid starvation^{2015, 2024} protein localization^{2010, 2024} protein localization to membrane^{2023, 2024} regulation of TOR signaling^{2015, 2024} protein localization to lysosome^{2023, 2024}
± 40 cellular response to nutrient levels^{2023, 2024} cellular response to leucine starvation^{2017, 2024} response to amino acid^{2016, 2024} regulation of TORC1 signaling^{2016, 2024} tumor necrosis factor-mediated signaling pathway^{2021, 2024} intracellular signal transduction^{2023, 2024} glucose homeostasis^{2023, 2024} cellular response to nitrogen starvation^{2015, 2017, 2019, 2024} cellular response to leucine^{2017, 2024} protein localization to vacuolar membrane^{2015, 2024} endocytic recycling^{2014, 2024} cellular response to oxidative stress^{2022, 2024} negative regulation of TORC1 signaling^{2023, 2024} lysosomal microautophagy^{2013, 2020, 2024} transcription by RNA polymerase III^{2013, 2024} transcription by RNA polymerase I^{2013, 2024} phosphate ion transport^{2005, 2013, 2024} determination of adult lifespan^{2011, 2012, 2024} apoptotic process^{2003, 2024} subtelomeric heterochromatin formation^{2021, 2024} positive regulation of transcription by RNA polymerase II^{2013, 2024} regulation of autophagosome assembly^{2012, 2024} positive regulation of multicellular organism growth^{2011, 2024} negative regulation of cell cycle switching, mitotic to meiotic cell cycle²⁰²¹ small GTPase mediated signal transduction²⁰⁰³ regulation of single-species biofilm formation on inanimate substrate²⁰¹⁷ regulation of lysosome organization²⁰¹⁷ regulation of cytolysis²⁰⁰⁶ regulation of autophagy²⁰¹² regulation of apoptotic cell clearance²⁰¹⁷ protein phosphorylation²⁰²⁴ proteasome-mediated ubiquitin-dependent protein catabolic process²⁰²¹ positive regulation of cell growth²⁰⁰⁹ piecemeal microautophagy of the nucleus²⁰²¹ multicellular organismal reproductive process²⁰¹¹ cytoplasm to vacuole transport by the Cvt pathway²⁰²¹ central nervous system myelination²⁰¹⁹ RNA splicing²⁰⁰³ Golgi to vacuole transport²⁰²¹ DNA-templated transcription²⁰⁰³

Cellular component: nucleus^{2003, 2006, 2009, 2013, 2023, 2024} lysosome^{2010, 2023, 2024} Gtr1-Gtr2 GTPase complex^{2013, 2017, 2018, 2021, 2024} cytoplasm^{2006, 2009, 2013, 2017, 2023, 2024} membrane²⁰²⁴ fungal-type vacuole membrane^{2015, 2018, 2020, 2021, 2024} lysosomal membrane^{2013, 2023, 2024} nucleoplasm^{2021, 2023, 2024} FNIP-folliculin RagC/D GAP^{2023, 2024} intracellular membrane-bounded organelle^{2023, 2024}
± 12 GATOR1 complex^{2015, 2024} Ragulator complex^{2020, 2021, 2024} centrosome^{2023, 2024} late endosome membrane^{2013, 2024} late endosome^{2014, 2024} cytosol^{2009, 2014, 2016} vacuole²⁰²⁴ vacuolar membrane²⁰²⁴ membrane raft^{2020, 2024} chromosome, telomeric region²⁰²⁴ chromatin^{2020, 2024} lipid droplet²⁰¹⁸