Biological process: phosphatase activity^{(2016, 2022, 2023)} metal ion binding^{(2022, 2023)} hydrolase activity⁽²⁰²³⁾ fructose-1-phosphatase activity⁽²⁰²³⁾ fructose 6-phosphate aldolase activity⁽²⁰²³⁾ protein carboxyl O-methyltransferase activity^{(2015, 2023)} methyltransferase activity⁽²⁰²³⁾ protein-glutamate O-methyltransferase activity⁽²⁰²³⁾ S-adenosylmethionine-dependent methyltransferase activity^{(2015, 2023)} enzyme binding^{(2015, 2023)}
± 13 transferase activity²⁰²³ inorganic diphosphate phosphatase activity²⁰²² zinc ion binding²⁰²³ steroid binding²⁰²³ sequence-specific DNA binding²⁰²³ nuclear steroid receptor activity²⁰²³ nuclear receptor activity²⁰²⁰ nuclear estrogen receptor activity²⁰²³ lipid binding²⁰²³ hormone binding²⁰²³ estrogen response element binding²⁰²² DNA-binding transcription factor activity²⁰²³ DNA binding²⁰²³

Molecular function: methylation²⁰²³ DNA damage response^{2015, 2022, 2023} protein methylation²⁰¹⁵ cellular detoxification²⁰¹⁷ steroid hormone mediated signaling pathway²⁰²³ response to organic cyclic compound²⁰²³ response to lipid²⁰²³ regulation of transcription by RNA polymerase II²⁰²³ regulation of DNA-templated transcription²⁰²³ intracellular estrogen receptor signaling pathway²⁰²²
± 1 cellular response to estrogen stimulus²⁰²²

Cellular component: nucleus^{2003, 2009, 2023} membrane²⁰²³ cytosol²⁰⁰⁹ cytoplasm^{2003, 2023}