Collated Gene Ontology terms

Biological process: polyubiquitin modification-dependent protein binding(2025)

Molecular function: regulation of ubiquitin-dependent protein catabolic process2019, 2025 protein ubiquitination2010, 2015, 2025 ubiquitin-dependent protein catabolic process2010, 2025 positive regulation of proteasomal ubiquitin-dependent protein catabolic process2010, 2025 response to type II interferon2010, 2025 response to tumor necrosis factor2010, 2025 proteolysis involved in protein catabolic process2025 proteasomal protein catabolic process2022

Cellular component: nucleus2015, 2018, 2022, 2025 nucleoplasm2024, 2025 nucleolus2024, 2025 Lewy body2022, 2025 cytosol2017, 2025 cytoplasm2015

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 1/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
NUB1_MOUSE
Ensembl»
4.3
Nub1 NEDD8 ultimate buster 1 (Negative regulator
of ubiquitin-like proteins 1) (Protein BS4)		 Mus musculus
TI:10090 None
 
NUB1_HUMAN
Ensembl»
5.3
NUB1 NEDD8 ultimate buster 1 (Negative regulator of
ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18)		 Homo sapiens
TI:9606 None
 
A0A8I3NGZ1_CANLF
Ensembl»
0.0
NUB1 NEDD8 ultimate buster 1 (Negative
regulator of ubiquitin-like proteins 1)		 Canis lupus
TI:9612 None
   
F1SSM7_PIG
Ensembl»
0.0
NUB1 NEDD8 ultimate buster 1 (Negative
regulator of ubiquitin-like proteins 1)		 Sus scrofa
TI:9823 None
   
F6VRJ6_MONDO
Ensembl»
0.0
NUB1 NEDD8 ultimate buster 1 (Negative
regulator of ubiquitin-like proteins 1)		 Monodelphis domestica
TI:13616 None
   
F7H5E5_MACMU
Ensembl»
0.0
NUB1 NEDD8 ultimate buster 1 (Negative
regulator of ubiquitin-like proteins 1)		 Macaca mulatta
TI:9544 None
   
A0A8I5ZLQ1_RAT
RGD»
3.0
Nub1 Negative regulator of ubiquitin-like proteins 1 Rattus norvegicus
TI:10116 None
   
E1BZ00_CHICK
Ensembl»
0.5
NUB1 Negative regulator of ubiquitin like proteins 1 Gallus gallus
TI:9031 None
   
F7AZ69_ORNAN
Ensembl»
0.0
NUB1 Negative regulator of ubiquitin like proteins 1 Ornithorhynchus anatinus
TI:9258 None
   
G1KLX0_ANOCA
Ensembl»
0.0
NUB1 Negative regulator of ubiquitin like proteins 1 Anolis carolinensis
TI:28377 None
   
NUB1_BOVIN
euHCVdb»
0.0
NUB1 NEDD8 ultimate buster 1 (Negative
regulator of ubiquitin-like proteins 1)		 Bos taurus
TI:9913 None
 
Q9VBQ3_DROME
FlyBase»
1.0
Dmel\CG5111 FI08017p Drosophila melanogaster
TI:7227 None
 
A0A1U8JH81_GOSHI
euHCVdb»
0.0
LOC107906939 NEDD8 ultimate buster 1 Gossypium hirsutum
TI:3635 None
   
A0A2I3SXX4_PANTR
Ensembl»
0.0
NUB1 NEDD8 ultimate buster 1 (Negative
regulator of ubiquitin-like proteins 1)		 Pan troglodytes
TI:9598 None
 
A0A9R0IQS8_SPIOL
neXtProt»
0.0
LOC110793302 Uncharacterized protein isoform X1 Spinacia oleracea
TI:3562 None
   
Q500V3_ARATH
TAIR»
0.5
NUB1 At2g12550 (Ubiquitin-associated
(UBA)/TS-N domain-containing protein)		 Arabidopsis thaliana
TI:3702 None
 
A0A072VIE6_MEDTR
EnsemblPlants»
0.0
25488333 NEDD8 ultimate buster-like protein Medicago truncatula
TI:3880 None
 
A0A0A0LI64_CUCSA
neXtProt»
0.0
Csa_2G008690 UBA domain-containing protein Cucumis sativus
TI:3659 None
 
A0A0R0FBE4_SOYBN
EnsemblPlants»
0.0
LOC100778435 UBA domain-containing protein Glycine max
TI:3847 None
 
A0A1D6DWJ6_MAIZE
EnsemblPlants»
0.0
LOC103645857 Ubiquitin-associated (UBA)/TS-N
domain-containing protein		 Zea mays
TI:4577 None
 
A0A1S3WXM7_TOBAC
neXtProt»
0.0
LOC107759083 Uncharacterized protein LOC107759083 Nicotiana tabacum
TI:4097 None
   
A0A1S4DRG6_TOBAC
euHCVdb»
0.0
LOC107832680 NEDD8 ultimate buster 1-like
(Uncharacterized protein LOC107832680 isoform X1)		 Nicotiana tabacum
TI:4097 None
   
A0A1U7YZ52_NELNU
euHCVdb»
0.0
LOC104588589 NEDD8 ultimate buster 1 Nelumbo nucifera
TI:4432 None
   
A0A1Y1HNB1_KLENI
euHCVdb»
0.0
KFL_000170150 Ubiquitin-associated (UBA)/TS-N
domain-containing protein		 Klebsormidium nitens
TI:105231 None
 
A0A251NH08_PRUPE
euHCVdb»
0.0
PRUPE_7G257500 UBA domain-containing protein Prunus persica
TI:3760 None
 
A0A251TQ00_HELAN
euHCVdb»
0.0
HannXRQ_Chr10g0314151 HanXRQr2_Chr10g0461721 Putative ubiquitin-associated (UBA)/TS-N domain-containing protein (UBA-like superfamily,
ubiquilin, Ubiquitin-like domain superfamily, NEDD8 ultimate buster 1)		 Helianthus annuus
TI:4232 None
 
A0A2C9UL06_MANES
euHCVdb»
0.0
MANES_14G119700v8 UBA domain-containing protein Manihot esculenta
TI:3983 None
 
A0A2I2YY49_GORGO
Ensembl»
0.0
NUB1 NEDD8 ultimate buster 1 (Negative
regulator of ubiquitin-like proteins 1)		 Gorilla gorilla
TI:9593 None
 
A0A2K1WZP3_POPTR
neXtProt»
0.0
POPTR_018G118100 UBA domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A2K3DZ26_CHLRE
neXtProt»
0.0
CHLRE_03g205650v5 Ubiquitin-like domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A3B6B6D2_WHEAT
EnsemblPlants»
0.0
LOC123190809 Ubiquitin-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6CHE4_WHEAT
EnsemblPlants»
0.0
LOC123047145 Ubiquitin-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6DLP7_WHEAT
EnsemblPlants»
0.0
LOC123054957 Ubiquitin-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3N7F1D0_POPTR
euHCVdb»
0.0
POPTR_006G061500 UBA domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A3Q7H3Q2_SOLLC
EnsemblPlants»
0.0
UBA domain-containing protein Solanum lycopersicum
TI:4081 None
   
A0A6P9EUE0_JUGRE
euHCVdb»
0.0
LOC109021041 NEDD8 ultimate buster 1-like Juglans regia
TI:51240 None
   
A0A7I4DB19_PHYPA
EnsemblPlants»
0.0
LOC112280009 NEDD8 ultimate buster 1 Physcomitrium patens
TI:3218 None
 
A0A804JMV5_MUSAM
EnsemblPlants»
0.0
NEDD8 ultimate buster 1 Musa acuminata
TI:4641 None
   
A0A8I6X1I2_HORVV
EnsemblPlants»
0.0
LOC123428174 NEDD8 ultimate buster 1 Hordeum vulgare
TI:4513 None
   
A0A8J1KWP3_XENLA
CTD»
0.0
nub1.L NEDD8 ultimate buster 1 isoform X2 Xenopus laevis
TI:8355 None
   
A0A9L0R3R3_HORSE
Ensembl»
0.0
NEDD8 ultimate buster 1 (Negative
regulator of ubiquitin-like proteins 1)		 Equus caballus
TI:9796 None
   
A0A9R1X9G5_LACSA
euHCVdb»
0.0
LSAT_V11C500262430 UBA domain-containing protein Lactuca sativa
TI:4236 None
 
A0ABM3AK29_GOSHI
euHCVdb»
0.0
LOC107913058 NEDD8 ultimate buster 1 Gossypium hirsutum
TI:3635 None
   
B9T241_RICCO
euHCVdb»
0.0
RCOM_0934400 NEDD8 ultimate buster, putative Ricinus communis
TI:3988 None
 
C5Y907_SORBI
euHCVdb»
0.0
SORBI_3006G237900 UBA domain-containing protein Sorghum bicolor
TI:4558 None
 
D7T4Y7_VITVI
neXtProt»
0.0
VIT_11s0118g00510 NEDD8 ultimate buster 1 Vitis vinifera
TI:29760 None
 
D8QQC3_SELML
euHCVdb»
0.0
SELMODRAFT_73901 UBA domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8R8L5_SELML
euHCVdb»
0.0
SELMODRAFT_169084 UBA domain-containing protein Selaginella moellendorffii
TI:88036 None
 
I1J2H9_BRADI
EnsemblPlants»
0.0
LOC100829250 UBA domain-containing protein Brachypodium distachyon
TI:15368 None
 
I1L286_SOYBN
EnsemblPlants»
0.0
LOC100792972 UBA domain-containing protein Glycine max
TI:3847 None
 
I1MHX4_SOYBN
EnsemblPlants»
0.0
LOC100804062 NEDD8 ultimate buster 1 Glycine max
TI:3847 None
 
K3Y5Y2_SETIT
EnsemblPlants»
0.0
LOC101763598 UBA domain-containing protein Setaria italica
TI:4555 None
 
M1D105_SOLTU
EnsemblPlants»
0.0
LOC102584013 NEDD8 ultimate buster Solanum tuberosum
TI:4113 None
   
M4D9J0_BRACM
EnsemblPlants»
0.0
NEDD8 ultimate buster 1 Brassica campestris
TI:3711 None
   
U5CWF7_AMBTC
euHCVdb»
0.0
AMTR_s00033p00177630 UBA domain-containing protein Amborella trichopoda
TI:13333 None
 
A0A022RHF2_ERYGU
neXtProt»
0.0
MIMGU_mgv1a003960mg UBA domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A061GP18_THECC
euHCVdb»
0.0
TCM_038205 Ubiquitin-associated (UBA)/TS-N
domain-containing protein		 Theobroma cacao
TI:3641 None
 
A0A067GDG5_CITSI
neXtProt»
0.0
CISIN_1g014748mg UBA domain-containing protein Citrus sinensis
TI:2711 None
 
A0A1S4H6U5_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A0A2G2Z0P5_CAPAN
neXtProt»
0.0
T459_18993 UBA domain-containing protein Capsicum annuum
TI:4072 None
 
A0A2K3DZ19_CHLRE
euHCVdb»
0.0
CHLRE_03g205700v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3DZ38_CHLRE
euHCVdb»
0.0
CHLRE_03g205701v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6WEG5_MARPO
neXtProt»
0.0
MARPO_0101s0042 UBA domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A7M7STL9_STRPU
EnsemblMetazoa»
0.0
Uncharacterized protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A9J7HLW5_BRAFL
neXtProt»
0.0
LOC118406065 NEDD8 ultimate buster 1-like Branchiostoma floridae
TI:7739 None
   
A0NAB7_ANOGA
EnsemblMetazoa»
0.0
AgaP_AGAP012858 AGAP012858-PA Anopheles gambiae
TI:7165 None
 
A2EAL3_TRIV3
TubercuList»
0.0
TVAG_491820 UBA/TS-N domain containing protein Trichomonas vaginalis
TI:5722 None
 
A2EAL8_TRIV3
TubercuList»
0.0
TVAG_491870 UBA/TS-N domain containing protein Trichomonas vaginalis
TI:5722 None
 
A2EGC9_TRIV3
TubercuList»
0.0
TVAG_401620 UBA/TS-N domain containing protein Trichomonas vaginalis
TI:5722 None
 
A4IJ16_XENTR
Xenbase»
0.0
nub1 NEDD8 ultimate buster 1 (Nyren18 protein) Xenopus tropicalis
TI:8364 None
 
A7RI15_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g178169 NEDD8 ultimate buster 1 Nematostella vectensis
TI:45351 None
 
B3RRC2_TRIAD
CTD»
0.0
TRIADDRAFT_54183 UBA domain-containing protein Trichoplax adhaerens
TI:10228 None
 
D2A289_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_07685 NEDD8 ultimate buster 1-like Protein Tribolium castaneum
TI:7070 None
 
E9GCZ7_DAPPU
neXtProt»
0.0
DAPPUDRAFT_223703 UBA domain-containing protein Daphnia pulex
TI:6669 None
 
F6QQ96_BOVIN
Ensembl»
0.0
NUB1 Negative regulator of ubiquitin like proteins 1 Bos taurus
TI:9913 None
   
F6WSZ7_CIOIN
Ensembl»
0.0
NEDD8 ultimate buster 1 Ciona intestinalis
TI:7719 None
 
H2LFB5_ORYLA
Ensembl»
0.0
nub1 Negative regulator of ubiquitin-like proteins 1 Oryzias latipes
TI:8090 None
   
Q9VRF3_DROME
FlyBase»
0.5
Dmel\CG15445 LD38858p (LP11713p) (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform E) (Uncharacterized
protein, isoform F) (Uncharacterized protein, isoform G) (Uncharacterized protein, isoform H)		 Drosophila melanogaster
TI:7227 None
 
T1FR59_HELRO
EnsemblMetazoa»
0.0
20211306 UBA domain-containing protein Helobdella robusta
TI:6412 None
 
W5MUZ8_LEPOC
Ensembl»
0.0
Negative regulator of ubiquitin like proteins 1 Lepisosteus oculatus
TI:7918 None
 
A0A1Y1I8S5_KLENI
euHCVdb»
0.0
KFL_003460100 Protein with Ubiquitin associated domain Klebsormidium nitens
TI:105231 None 		 
 
A0A6P9ERW1_JUGRE
euHCVdb»
0.0
LOC109020480 NEDD8 ultimate buster 1-like Juglans regia
TI:51240 None 		     
A0A804JMV7_MUSAM
EnsemblPlants»
0.0
GSMUA_178570.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None 		 
 
A0A804JMV9_MUSAM
EnsemblPlants»
0.0
GSMUA_178590.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None 		 
 
A0A8M3AW93_DANRE
ZFIN»
0.0
nub1 NEDD8 ultimate buster 1 Danio rerio
TI:7955 None 		     
A0A9L0S0Y1_HORSE
Ensembl»
0.0
NEDD8 ultimate buster
1 ubiquitin-like domain-containing protein		 Equus caballus
TI:9796 None 		     
A0AAD9T842_EUCGR
euHCVdb»
0.0
EUGRSUZ_L03235 UBA domain-containing protein Eucalyptus grandis
TI:71139 None 		 
 
A0AAD9WGU5_EUCGR
neXtProt»
0.0
EUGRSUZ_L03187 UBA domain-containing protein Eucalyptus grandis
TI:71139 None 		 
 
A0ABI7XW73_FELCA
Ensembl»
0.0
NUB1 UBA domain-containing protein Felis catus
TI:9685 None 		     
A7RI20_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g197428 Uncharacterized protein Nematostella vectensis
TI:45351 None 		 
 
B7PK54_IXOSC
EnsemblMetazoa»
0.0
8030156 UBA domain-containing protein Ixodes scapularis
TI:6945 None 		 
 
B7PK55_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW005082 Uncharacterized protein Ixodes scapularis
TI:6945 None 		 
 
B9SMQ4_RICCO
neXtProt»
0.0
RCOM_1627520 Ubiquitin-like domain-containing protein Ricinus communis
TI:3988 None 		 
 
Q0J9L6_ORYSJ
euHCVdb»
0.0
Os04g0644300 Os04g0644300 protein Oryza sativa
TI:4530 None