Collated Gene Ontology terms

Biological process: oxidoreductase activity(2024) transferase activity(2024) protein homodimerization activity(2014) heme binding(2012) dihydrokaempferol 4-reductase activity(2024) cholesterol 26-hydroxylase activity(2012) cholest-4-en-3-one 26-monooxygenase activity(2012) acyltransferase activity, transferring groups other than amino-acyl groups(2024)

Molecular function: cholesterol catabolic process2012 chloroplast fission2005

Cellular component: membrane2024 chloroplast2021, 2024 plastid inner membrane2024 plastid2005 plasma membrane2010 peptidoglycan-based cell wall2012 nucleus2014 mitochondrion2024 chloroplast inner membrane2024 chloroplast envelope2021

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 20/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
U5D7I4_AMBTC
EnsemblPlants»
0.0
AMTR_s00182p00029890 NAD-dependent epimerase/dehydratase
domain-containing protein		 Amborella trichopoda
TI:13333 None 		 
 
H9GER6_ANOCA
Ensembl»
0.0
sdr39u1 NAD-dependent epimerase/dehydratase
domain-containing protein		 Anolis carolinensis
TI:28377 None 		     
Q7PRQ8_ANOGA
EnsemblMetazoa»
0.0
1272419 AGAP000649-PA Anopheles gambiae
TI:7165 None 		 
 
GC1_ARATH
TAIR»
1.6
GC1 Epimerase family protein SDR39U1 homolog, chloroplastic (EC 1.1.1.-)
(Protein GIANT CHLOROPLAST 1) (Protein SulA homolog) (AtSulA)		 Arabidopsis thaliana
TI:3702 None
 
Q81I98_BACCR
EnsemblBacteria»
0.0
BC_0497 Cell division inhibitor Bacillus cereus
TI:1396 None 		 
 
YFHF_BACSU
EnsemblBacteria»
0.0
yfhF Epimerase family protein YfhF Bacillus subtilis
TI:1423 None 		 
 
Q89Z84_BACTN
EnsemblBacteria»
0.0
BT_4493 Sugar nucleotide epimerase Bacteroides thetaiotaomicron
TI:818 None 		 
 
D39U1_BOVIN
CTD»
0.0
SDR39U1 Epimerase family protein SDR39U1 (EC 1.1.1.-)
(Short-chain dehydrogenase/reductase family 39U member 1)		 Bos taurus
TI:9913 None
 
F1MK41_BOVIN
Ensembl»
0.0
SDR39U1 Short chain dehydrogenase/reductase
family 39U member 1		 Bos taurus
TI:9913 None 		     
I1IFV5_BRADI
EnsemblPlants»
0.0
BRADI_3g60920v3 NAD-dependent epimerase/dehydratase
domain-containing protein		 Brachypodium distachyon
TI:15368 None 		 
 
Q89JM2_BRADU
EnsemblBacteria»
0.0
bll5261 Bll5261 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
A0A9J7LCJ0_BRAFL
CTD»
0.0
LOC118418001 Epimerase family protein SDR39U1-like isoform X1 Branchiostoma floridae
TI:7739 None
   
A0A078FRY4_BRANA
EnsemblPlants»
0.0
BnaA04g12100D (rape) hypothetical
protein (BnaA04g12100D protein)		 Brassica napus
TI:3708 None 		 
 
A0A078GTD3_BRANA
EnsemblPlants»
0.0
BnaA07g04880D BnaA07g04880D protein Brassica napus
TI:3708 None 		 
 
A0A078J7S7_BRANA
EnsemblPlants»
0.0
BnaA06g40070D BnaA06g40070D protein Brassica napus
TI:3708 None 		 
 
M4DF49_BRACM
EnsemblPlants»
0.0
NAD-dependent epimerase/dehydratase
domain-containing protein		 Brassica campestris
TI:3711 None 		     
M4END6_BRACM
EnsemblPlants»
0.0
NAD-dependent epimerase/dehydratase
domain-containing protein		 Brassica campestris
TI:3711 None 		     
A0A8I3N3T9_CANLF
Ensembl»
0.0
SDR39U1 Short chain dehydrogenase/reductase
family 39U member 1		 Canis lupus
TI:9612 None 		     
A0A1U8EZT9_CAPAN
EnsemblPlants»
0.0
T459_07439 Epimerase family protein
SDR39U1-like protein, chloroplastic		 Capsicum annuum
TI:4072 None 		 
 
A0A2K3DRU1_CHLRE
EnsemblPlants»
0.0
CHLRE_05g233305v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
A9WFR2_CHLAA
EnsemblBacteria»
0.0
Caur_2203 NAD-dependent epimerase/dehydratase Chloroflexus aurantiacus
TI:1108 None 		 
 
H2XJN9_CIOIN
Ensembl»
0.0
LOC100181474 Epimerase family protein SDR39U1 Ciona intestinalis
TI:7719 None 		 
 
A0A067E7L1_CITSI
Ensembl»
0.0
CISIN_1g017751mg DUF1731 domain-containing protein Citrus sinensis
TI:2711 None 		 
 
A0A0A0K2D2_CUCSA
EnsemblPlants»
0.0
Csa_7G006290 NAD-dependent epimerase/dehydratase
domain-containing protein		 Cucumis sativus
TI:3659 None 		 
 
Q08C46_DANRE
ZFIN»
0.0
zgc:153633 Epimerase family protein SDR39U1 (Zgc:153633) Danio rerio
TI:7955 None 		 
 
E9GAX2_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_301869 Epimerase family protein SDR39U1 Daphnia pulex
TI:6669 None 		 
 
F1A0E6_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_41579 DUF1731 domain-containing protein Dictyostelium purpureum
TI:5786 None 		 
 
Q54W18_DICDI
dictyBase»
0.0
DDB_G0279965 NAD-dependent epimerase/dehydratase
family protein		 Dictyostelium discoideum
TI:44689 None 		 
 
Q8T0N5_DROME
FlyBase»
0.0
Dmel\CG8768 GH17516p Drosophila melanogaster
TI:7227 None 		 
 
A0A022RK83_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a009159mg DUF1731 domain-containing protein Erythranthe guttata
TI:4155 None 		 
 
YFCH_ECOLI
EnsemblBacteria»
0.0
yfcH Epimerase family protein YfcH Escherichia coli
TI:562 None 		 
 
A0A2I2UNQ2_FELCA
Ensembl»
0.0
SDR39U1 Short chain dehydrogenase/reductase
family 39U member 1		 Felis catus
TI:9685 None 		 
 
I1LJ50_SOYBN
EnsemblPlants»
0.0
GLYMA_11G110000 DUF1731 domain-containing protein Glycine max
TI:3847 None 		 
 
I1LPX1_SOYBN
EnsemblPlants»
0.0
100814881 NAD-dependent epimerase/dehydratase
domain-containing protein		 Glycine max
TI:3847 None 		 
 
G3S9N1_GORGO
Ensembl»
0.0
SDR39U1 Short chain dehydrogenase/reductase
family 39U member 1		 Gorilla gorilla
TI:9593 None 		 
 
A0A1U8LIW6_GOSHI
Ensembl»
0.0
LOC107927930 Epimerase family protein
SDR39U1 homolog, chloroplastic		 Gossypium hirsutum
TI:3635 None 		     
Y1208_HAEIN
EnsemblBacteria»
0.0
HI_1208 Epimerase family protein HI_1208 Haemophilus influenzae
TI:727 None 		 
 
A0A9K3DJL5_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr17g0807231 Farnesol dehydrogenase (NAD(+)) (EC 1.1.1.354) Helianthus annuus
TI:4232 None
 
T1FY29_HELRO
EnsemblMetazoa»
0.0
20213727 DUF1731 domain-containing protein Helobdella robusta
TI:6412 None 		 
 
D39U1_HUMAN
Ensembl»
0.0
SDR39U1 Epimerase family protein SDR39U1 (EC 1.1.1.-)
(Short-chain dehydrogenase/reductase family 39U member 1)		 Homo sapiens
TI:9606 None
 
A0A8I6Z5E9_HORVV
EnsemblPlants»
0.0
Epimerase family protein
SDR39U1 homolog, chloroplastic		 Hordeum vulgare
TI:4513 None 		     
B7PP18_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW019145 DUF1731 domain-containing protein Ixodes scapularis
TI:6945 None 		 
 
A0A2I4E7I0_JUGRE
EnsemblPlants»
0.0
LOC108986994 Epimerase family protein
SDR39U1 homolog, chloroplastic		 Juglans regia
TI:51240 None 		 
 
A0A1Y1IW79_KLENI
EnsemblPlants»
0.0
KFL_013280010 Uncharacterized protein Klebsormidium nitens
TI:105231 None 		 
 
Q8EZH4_LEPIN
EnsemblBacteria»
0.0
LA_3879 Predicted nucleoside-diphosphate sugar epimerase Leptospira interrogans
TI:173 None 		 
 
Q8F125_LEPIN
EnsemblBacteria»
0.0
LA_3314 Cell division inhibitor Leptospira interrogans
TI:173 None 		 
 
Q8Y6J0_LISMO
EnsemblBacteria»
0.0
lmo1694 Lmo1694 protein Listeria monocytogenes
TI:1639 None 		 
 
F6YM95_MACMU
Ensembl»
0.0
SDR39U1 Short chain dehydrogenase/reductase
family 39U member 1		 Macaca mulatta
TI:9544 None 		     
A0A2C9W0M8_MANES
EnsemblPlants»
0.0
MANES_04G083100 NAD-dependent epimerase/dehydratase
domain-containing protein		 Manihot esculenta
TI:3983 None 		 
 
A0A2R6XDG3_MARPO
EnsemblPlants»
0.0
MARPO_0021s0030 DUF1731 domain-containing protein Marchantia polymorpha
TI:3197 None 		 
 
G7JJX2_MEDTR
EnsemblPlants»
0.0
11443607 NAD(P)-binding rossmann-fold protein (Putative
dihydroflavanol 4-reductase (EC 1.1.1.219))		 Medicago truncatula
TI:3880 None
 
F6PMJ2_MONDO
Ensembl»
0.0
SDR39U1 Short chain dehydrogenase/reductase
family 39U member 1		 Monodelphis domestica
TI:13616 None 		     
D39U1_MOUSE
Ensembl»
0.0
Sdr39u1 Epimerase family protein SDR39U1 (EC 1.1.1.-)
(Short-chain dehydrogenase/reductase family 39U member 1)		 Mus musculus
TI:10090 None
 
A0A804HS65_MUSAM
EnsemblPlants»
0.0
103984239 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None 		 
 
Y2216_MYCTU
TubercuList»
0.0
Rv2216 Epimerase family protein Rv2216 Mycobacterium tuberculosis
TI:1773 None
 
A0A1U8AN40_NELNU
EnsemblBacteria»
0.0
LOC104602045 Epimerase family protein
SDR39U1 homolog, chloroplastic		 Nelumbo nucifera
TI:4432 None 		     
A7RRE4_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g161857 Epimerase family protein SDR39U1 Nematostella vectensis
TI:45351 None 		 
 
A0A1S3YBI5_TOBAC
EnsemblFungi»
0.0
LOC107774381 Epimerase family protein
SDR39U1 homolog, chloroplastic-like		 Nicotiana tabacum
TI:4097 None 		     
A0A1S3YVL2_TOBAC
EnsemblFungi»
0.0
LOC107780014 Epimerase family protein SDR39U1
homolog, chloroplastic-like isoform X1		 Nicotiana tabacum
TI:4097 None 		     
A0A1S3Z4Y2_TOBAC
EnsemblFungi»
0.0
LOC107782972 Epimerase family protein
SDR39U1 homolog, chloroplastic-like		 Nicotiana tabacum
TI:4097 None 		     
A0A6I8P3M0_ORNAN
Ensembl»
0.0
SDR39U1 Short chain dehydrogenase/reductase
family 39U member 1		 Ornithorhynchus anatinus
TI:9258 None 		     
Q6EP22_ORYSJ
EnsemblPlants»
0.0
Os02g0834700 Os02g0834700 protein Oryza sativa
TI:4530 None 		 
 
A0A3B3I6F3_ORYLA
Ensembl»
0.0
sdr39u1 Short chain dehydrogenase/reductase
family 39U member 1		 Oryzias latipes
TI:8090 None 		     
A0A2I3R9T8_PANTR
Ensembl»
0.0
SDR39U1 Short chain dehydrogenase/reductase
family 39U member 1		 Pan troglodytes
TI:9598 None 		 
 
A0A7I4E3K8_PHYPA
EnsemblPlants»
0.0
DUF1731 domain-containing protein Physcomitrium patens
TI:3218 None 		 
 
B9HRF3_POPTR
EnsemblPlants»
0.0
POPTR_009G124800 NAD-dependent epimerase/dehydratase
domain-containing protein		 Populus trichocarpa
TI:3694 None 		 
 
A0A251MV10_PRUPE
EnsemblPlants»
0.0
PRUPE_8G083600 DUF1731 domain-containing protein Prunus persica
TI:3760 None 		 
 
Q9HVD6_PSEAE
EnsemblBacteria»
0.0
PA4656 TIGR01777 family protein Pseudomonas aeruginosa
TI:287 None 		 
 
D3ZYY0_RAT
RGD»
0.0
Sdr39u1 Short chain dehydrogenase/reductase
family 39U, member 1		 Rattus norvegicus
TI:10116 None 		     
Q7TTQ0_RHOBA
EnsemblBacteria»
0.0
RB1391 Hypothetical 317 kDa
protein-putative nucleoside-diphosphate sugar epimerase		 Rhodopirellula baltica
TI:265606 None 		 
 
B9RG50_RICCO
EnsemblBacteria»
0.0
RCOM_1450710 Cell division inhibitor Ricinus communis
TI:3988 None 		 
 
Q8ZNC8_SALTY
EnsemblBacteria»
0.0
yfcH Sugar nucleotide epimerase Salmonella typhimurium
TI:28901 None 		 
 
D8RQA2_SELML
EnsemblPlants»
0.0
SELMODRAFT_173339 DUF1731 domain-containing protein Selaginella moellendorffii
TI:88036 None 		 
 
D8TDF1_SELML
EnsemblPlants»
0.0
SELMODRAFT_270068 DUF1731 domain-containing protein Selaginella moellendorffii
TI:88036 None 		 
 
K3YZU2_SETIT
EnsemblPlants»
0.0
101767905 NAD-dependent epimerase/dehydratase
domain-containing protein		 Setaria italica
TI:4555 None 		 
 
Q8ED48_SHEON
EnsemblPlants»
0.0
yfcH Predicted nucleoside-diphosphate
sugar epimerase YfcH		 Shewanella oneidensis
TI:70863 None 		 
 
A0A3Q7I8C3_SOLLC
EnsemblPlants»
0.0
N-acetyltransferase domain-containing protein Solanum lycopersicum
TI:4081 None
   
M1D3D7_SOLTU
EnsemblPlants»
0.0
Cell division inhibitor Solanum tuberosum
TI:4113 None 		     
A0A194YTC8_SORBI
EnsemblPlants»
0.0
SORBI_3004G359600 DUF1731 domain-containing protein Sorghum bicolor
TI:4558 None
 
Y792_STAA8
EnsemblBacteria»
0.0
SAOUHSC_00792 Epimerase family protein SAOUHSC_00792 Staphylococcus aureus
TI:1280 None 		 
 
Q9S2P6_STRCO
EnsemblBacteria»
0.0
SCO2190 TIGR01777 family protein Streptomyces coelicolor
TI:1902 None 		 
 
A0A7M7N974_STRPU
EnsemblMetazoa»
0.0
Epimerase family protein SDR39U1 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A287A9T9_PIG
Ensembl»
0.0
SDR39U1 Short chain dehydrogenase/reductase
family 39U member 1		 Sus scrofa
TI:9823 None 		     
Y1223_SYNY3
EnsemblBacteria»
0.0
slr1223 Epimerase family protein slr1223 Synechocystis sp.
TI:1148 None 		 
 
A0A061E6F4_THECC
EnsemblPlants»
0.0
TCM_006776 NAD(P)-binding Rossmann-fold superfamily protein Theobroma cacao
TI:3641 None 		 
 
D6WDT7_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_03713 Epimerase family protein SDR39U1-like Protein Tribolium castaneum
TI:7070 None 		 
 
A0A3B6NYH4_WHEAT
EnsemblPlants»
0.0
CFC21_085647 NAD-dependent epimerase/dehydratase
domain-containing protein		 Triticum aestivum
TI:4565 None 		 
 
A0A3B6PW33_WHEAT
EnsemblPlants»
0.0
CFC21_090615 NAD-dependent epimerase/dehydratase
domain-containing protein		 Triticum aestivum
TI:4565 None 		 
 
A0A3B6TR23_WHEAT
EnsemblPlants»
0.0
CFC21_111346 NAD-dependent epimerase/dehydratase
domain-containing protein		 Triticum aestivum
TI:4565 None 		 
 
RCP_VIBCH
EnsemblBacteria»
0.0
rcp Protein Rcp (Protein SulA) Vibrio cholerae
TI:666 None 		 
 
D7U5G5_VITVI
EnsemblPlants»
0.0
VIT_03s0038g00740 Epimerase family
protein SDR39U1-like, chloroplastic		 Vitis vinifera
TI:29760 None 		 
 
Q8P426_XANCP
EnsemblBacteria»
0.0
sulA Cell division inhibitor Xanthomonas campestris
TI:339 None 		 
 
A0A1L8HPP5_XENLA
Xenbase»
0.0
LOC108707038 Epimerase family protein SDR39U1 isoform X1 Xenopus laevis
TI:8355 None 		     
B7ZT44_XENTR
Xenbase»
0.0
sdr39u1 Epimerase family protein SDR39U1 Xenopus tropicalis
TI:8364 None 		 
 
A0A380PFV7_YERPE
EnsemblBacteria»
0.0
YPO2778 TIGR01777 family protein Yersinia pestis
TI:632 None 		 
 
A0A1D6HQF7_MAIZE
EnsemblPlants»
0.0
ZEAMMB73_Zm00001d018575 Epimerase family protein
SDR39U1 homolog chloroplastic		 Zea mays
TI:4577 None 		 
 
A0A0K9P313_ZOSMR
EnsemblPlants»
0.0
ZOSMA_40G00020 NAD-dependent epimerase/dehydratase
domain-containing protein		 Zostera marina
TI:29655 None 		 
   
A0A0K9P420_ZOSMR
EnsemblPlants»
0.0
ZOSMA_431G00010 Uncharacterized protein Zostera marina
TI:29655 None 		 
   
A0A0K9P9D8_ZOSMR
EnsemblPlants»
0.0
ZOSMA_348G00090 NAD-dependent epimerase/dehydratase Zostera marina
TI:29655 None