Collated Gene Ontology terms

Biological process: nucleotide binding(2023) ATP binding(2023) alanine-tRNA ligase activity(2023) nucleic acid binding(2023) aminoacyl-tRNA ligase activity(2023) Ser-tRNA(Ala) hydrolase activity(2011, 2012, 2022, 2023) catalytic activity, acting on a tRNA(2023) aminoacyl-tRNA editing activity(2010, 2023) ligase activity(2023) metal ion binding(2023)
hydrolase activity2023 zinc ion binding2022

Molecular function: alanyl-tRNA aminoacylation2023 tRNA aminoacylation2023 regulation of translational fidelity2011, 2023 aminoacyl-tRNA metabolism involved in translational fidelity2023 tRNA metabolic process2023 translation2023

Cellular component: mitochondrion2023 cytoplasm2003, 2017, 2023 nucleus2014 membrane2023 chloroplast2023

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 10/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 3/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 28/39 
Archea: 5/8 
Bacteria: 8/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
W1P5G8_AMBTC
EnsemblPlants»
0.0
AMTR_s00045p00197400 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Amborella trichopoda
TI:13333 None
 
R4GCQ3_ANOCA
Ensembl»
0.0
AARSD1 Alanyl-tRNA synthetase domain containing 1 Anolis carolinensis
TI:28377 None
   
Q7QDK1_ANOGA
EnsemblMetazoa»
0.0
1272786 AGAP003413-PA Anopheles gambiae
TI:7165 None
 
A0A1I9LMV6_ARATH
TAIR»
0.0
At3g16565 Threonyl and alanyl tRNA
synthetase second additional domain-containing protein		 Arabidopsis thaliana
TI:3702 None
 
Q4WBR3_ASPFU
EnsemblFungi»
0.0
AFUA_8G07110 Alanyl-tRNA synthetase, putative (EC 6.1.1.7) Aspergillus fumigatus
TI:746128 None
 
Q81FC2_BACCR
EnsemblBacteria»
0.0
BC_1672 Metal-dependent hydrolase related
to alanyl-tRNA synthetase		 Bacillus cereus
TI:1396 None
 
Q8AA99_BACTN
EnsemblBacteria»
0.0
BT_0566 Alanyl-tRNA synthetase Bacteroides thetaiotaomicron
TI:818 None
 
F4P3A1_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_36953 Threonyl/alanyl tRNA synthetase
SAD domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None
 
AASD1_BOVIN
CTD»
0.0
AARSD1 Alanyl-tRNA editing protein Aarsd1
(Alanyl-tRNA synthetase domain-containing protein 1)		 Bos taurus
TI:9913 None
 
F1MZR1_BOVIN
Ensembl»
0.0
AARSD1 Alanyl-tRNA synthetase domain containing 1 Bos taurus
TI:9913 None
   
A0A0Q3I9G6_BRADI
EnsemblPlants»
0.0
100840915 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Brachypodium distachyon
TI:15368 None
 
C3XTB1_BRAFL
CTD»
0.0
LOC118403646 Alanyl-tRNA editing protein Aarsd1-like Branchiostoma floridae
TI:7739 None
 
A0A078I1Z7_BRANA
EnsemblPlants»
0.0
BnaC05g36690D BnaC05g36690D protein Brassica napus
TI:3708 None
 
A0A1D8PFC1_CANAL
EnsemblFungi»
0.0
CAALFM_C112240CA orf19.12703 Alanine--tRNA ligase Candida albicans
TI:5476 None
 
A0A8I3N0E9_CANLF
Ensembl»
0.0
AARSD1 Alanyl-tRNA synthetase domain containing 1 Canis lupus
TI:9612 None
   
A0A2K3CYJ8_CHLRE
EnsemblPlants»
0.0
CHLRE_14g628400v5 Threonyl/alanyl tRNA synthetase
SAD domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None
 
A9WGQ1_CHLAA
EnsemblBacteria»
0.0
Caur_3018 Threonyl/alanyl tRNA synthetase SAD Chloroflexus aurantiacus
TI:1108 None
 
F6Q5L2_CIOIN
Ensembl»
0.0
Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Ciona intestinalis
TI:7719 None
 
A0A067G896_CITSI
Ensembl»
0.0
CISIN_1g0250981mg Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Citrus sinensis
TI:2711 None
 
Q5KP36_CRYNJ
EnsemblFungi»
0.0
CNA04320 Cytoplasm protein, putative Cryptococcus neoformans
TI:5207 None
 
AASD1_DANRE
ZFIN»
1.0
aarsd1 Alanyl-tRNA editing protein Aarsd1
(Alanyl-tRNA synthetase domain-containing protein 1)		 Danio rerio
TI:7955 None
 
E9G0N4_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_312382 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Daphnia pulex
TI:6669 None
 
B8E0L2_DICTD
EnsemblBacteria»
0.0
Dtur_1760 Threonyl/alanyl tRNA synthetase SAD Dictyoglomus turgidum
TI:513050 None
 
F0Z8M8_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_85978 Uncharacterized protein Dictyostelium purpureum
TI:5786 None
 
Q9W4R9_DROME
FlyBase»
1.0
anon-EST:Posey113 LD13611p (Uncharacterized protein,
isoform A (EC 6.1.1.7))		 Drosophila melanogaster
TI:7227 None
 
C8VA46_EMENI
EnsemblFungi»
0.0
ANIA_11110 Alanyl-tRNA synthetase,
putative (AFU_orthologue AFUA_8G07110)		 Emericella nidulans
TI:162425 None
 
A0A022RYF7_ERYGU
Ensembl»
0.0
MIMGU_mgv1a012367mg Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Erythranthe guttata
TI:4155 None
 
A0A059D185_EUCGR
EnsemblPlants»
0.0
EUGRSUZ_B01310 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Eucalyptus grandis
TI:71139 None
 
A0A2I2UVG8_FELCA
Ensembl»
0.0
AARSD1 Alanyl-tRNA synthetase domain containing 1 Felis catus
TI:9685 None
 
Q8RFZ8_FUSNN
EnsemblBacteria»
0.0
FN0527 Alanyl-tRNA synthetase (EC 6.1.1.7) Fusobacterium nucleatum
TI:851 None
 
F1NC49_CHICK
Ensembl»
1.0
AARSD1 Alanyl-tRNA synthetase domain containing 1 Gallus gallus
TI:9031 None
   
A8BQ23_GIAIC
EnsemblProtists»
0.0
GL50803_0015078 GL50803_15078 Metal-dependent hydrolase related to
alanyl-tRNA synthetase (Misacylated tRNA(Ala) deacylase)		 Giardia intestinalis
TI:5741 None
 
A0A0R0EUF7_SOYBN
EnsemblPlants»
0.0
GLYMA_19G060100 Uncharacterized protein Glycine max
TI:3847 None 		 
   
A0A0R0F7N9_SOYBN
EnsemblPlants»
0.0
GLYMA_17G026200 Alanyl-tRNA synthetase class
IIc N-terminal domain-containing protein		 Glycine max
TI:3847 None 		 
 
A0A0R0FCI9_SOYBN
EnsemblPlants»
0.0
GLYMA_18G167200 Uncharacterized protein Glycine max
TI:3847 None 		 
   
I1KMZ3_SOYBN
EnsemblPlants»
0.0
GLYMA_07G247900 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Glycine max
TI:3847 None
 
G3SH26_GORGO
Ensembl»
0.0
Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Gorilla gorilla
TI:9593 None
 
A0A1U8LWD8_GOSHI
Ensembl»
0.0
LOC107931493 Alanine--tRNA ligase-like isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1U8M8W5_GOSHI
Ensembl»
0.0
LOC107935157 Alanine--tRNA ligase-like isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A251V8F3_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr03g0080751 HanXRQr2_Chr03g0123171 Alanine--tRNA ligase (EC
6.1.1.7) (Putative alanine-tRNA ligase)		 Helianthus annuus
TI:4232 None
 
T1EFK0_HELRO
EnsemblMetazoa»
0.0
20195352 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Helobdella robusta
TI:6412 None
 
AASD1_HUMAN
Ensembl»
1.0
AARSD1 Alanyl-tRNA editing protein Aarsd1
(Alanyl-tRNA synthetase domain-containing protein 1)		 Homo sapiens
TI:9606 None
 
F2DSU4_HORVV
EnsemblPlants»
0.0
Predicted protein Hordeum vulgare
TI:4513 None
 
B7QDD1_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW013423 Alanyl-tRNA synthetase, putative (EC 6.1.1.7) Ixodes scapularis
TI:6945 None
 
B1L4V0_KORCO
EnsemblBacteria»
0.0
Kcr_0729 Threonyl/alanyl tRNA synthetase SAD Korarchaeum cryptofilum
TI:498846 None
 
B1L4W6_KORCO
EnsemblBacteria»
0.0
Kcr_0747 Threonyl/alanyl tRNA synthetase SAD Korarchaeum cryptofilum
TI:498846 None
 
B1L5H7_KORCO
EnsemblBacteria»
0.0
Kcr_0960 Threonyl/alanyl tRNA synthetase SAD Korarchaeum cryptofilum
TI:498846 None
 
Q4QFB6_LEIMA
EnsemblProtists»
0.0
LMJF_15_0690 Threonyl/alanyl tRNA synthetase
SAD domain-containing protein		 Leishmania major
TI:5664 None
 
W5N324_LEPOC
Ensembl»
0.0
Alanyl-tRNA synthetase domain containing 1 Lepisosteus oculatus
TI:7918 None
 
F6PQH0_MACMU
Ensembl»
0.0
AARSD1 Alanyl-tRNA synthetase domain containing 1 Macaca mulatta
TI:9544 None
   
A0A2C9W8X8_MANES
EnsemblPlants»
0.0
MANES_03G194700 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Manihot esculenta
TI:3983 None
 
G7JLH0_MEDTR
EnsemblPlants»
0.0
11413170 Alanyl-tRNA synthetase (Putative
alanine--tRNA ligase (EC 6.1.1.7))		 Medicago truncatula
TI:3880 None
 
G7JPZ7_MEDTR
EnsemblPlants»
0.0
MTR_4g123440 Alanyl-tRNA synthetase Medicago truncatula
TI:3880 None
 
ALAXM_METAC
EnsemblBacteria»
0.0
alaXM Alanyl-tRNA editing protein AlaX-M
(AlaX-M) (Alanyl-tRNA deacylase AlaX-M)		 Methanosarcina acetivorans
TI:2214 None
 
F7F360_MONDO
Ensembl»
0.0
AARSD1 Alanyl-tRNA synthetase domain containing 1 Monodelphis domestica
TI:13616 None
   
A2A4P3_MOUSE
Ensembl»
0.0
Gm27029 Predicted gene, 27029 Mus musculus
TI:10090 None
   
AASD1_MOUSE
Ensembl»
3.4
Aarsd1 Alanyl-tRNA editing protein Aarsd1 (Alanyl-tRNA deacylase alaX)
(AlaX) (AlaXp-II) (Alanyl-tRNA synthetase domain-containing protein 1)		 Mus musculus
TI:10090 None
 
A0A804KY92_MUSAM
EnsemblPlants»
0.0
103968738 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A1U8ABX8_NELNU
EnsemblBacteria»
0.0
LOC104598985 Uncharacterized protein LOC104598985 isoform X1 Nelumbo nucifera
TI:4432 None
   
A7RHY7_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g158880 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Nematostella vectensis
TI:45351 None
 
Q7SDK9_NEUCR
EnsemblFungi»
0.0
NCU00535 Alanyl-tRNA synthetase Neurospora crassa
TI:5141 None
 
F6S764_ORNAN
Ensembl»
0.0
AARSD1 Alanyl-tRNA synthetase domain containing 1 Ornithorhynchus anatinus
TI:9258 None
   
Q5ZDT9_ORYSJ
EnsemblPlants»
0.0
Os01g0120400 Os01g0120400 protein (cDNA clone:001-038-F08, full insert
sequence) (cDNA clone:006-309-G11, full insert sequence)		 Oryza sativa
TI:4530 None
 
A0A3B3I659_ORYLA
Ensembl»
0.0
LOC101172535 Alanyl-tRNA editing protein Aarsd1 Oryzias latipes
TI:8090 None
   
A0A2I3RZV4_PANTR
Ensembl»
0.0
PTGES3L Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Pan troglodytes
TI:9598 None
 
A0BPM0_PARTE
EnsemblProtists»
0.0
GSPATT00005236001 Chromosome undetermined scaffold_12,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0CKM4_PARTE
EnsemblProtists»
0.0
GSPATT00001055001 Chromosome undetermined scaffold_2,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
Q0V2U3_PHANO
EnsemblFungi»
0.0
SNOG_01671 Alanyl-tRNA synthetase class
IIc N-terminal domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None 		 
 
Q0V4U5_PHANO
EnsemblFungi»
0.0
SNOG_00969 Threonyl/alanyl tRNA synthetase
SAD domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
A0A7I4C030_PHYPA
EnsemblPlants»
0.0
Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Physcomitrium patens
TI:3218 None
 
H3HDB9_PHYRM
EnsemblProtists»
0.0
Threonyl/alanyl tRNA synthetase
SAD domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
B9HSB4_POPTR
EnsemblPlants»
0.0
POPTR_010G024900 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Populus trichocarpa
TI:3694 None
 
M5XFI4_PRUPE
EnsemblPlants»
0.0
PRUPE_1G137400 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Prunus persica
TI:3760 None
 
Q9I209_PSEAE
EnsemblBacteria»
0.0
PA2106 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Pseudomonas aeruginosa
TI:287 None
 
Q8ZVE9_PYRAE
EnsemblBacteria»
0.0
PAE2317 Alanyl-tRNA synthetase related protein Pyrobaculum aerophilum
TI:13773 None
 
AASD1_RAT
RGD»
2.5
Aarsd1 Alanyl-tRNA editing protein Aarsd1
(Alanyl-tRNA synthetase domain-containing protein 1)		 Rattus norvegicus
TI:10116 None
 
B9RT44_RICCO
EnsemblBacteria»
0.0
RCOM_0680890 Threonyl/alanyl tRNA synthetase
SAD domain-containing protein		 Ricinus communis
TI:3988 None
 
ALAXM_SACS2
EnsemblBacteria»
0.0
alaXM Alanyl-tRNA editing protein AlaX-M
(AlaX-M) (Alanyl-tRNA deacylase AlaX-M)		 Saccharolobus solfataricus
TI:2287 None
 
Q97YQ3_SACS2
EnsemblBacteria»
0.0
alaS-like2 Alanyl-tRNA synthetase
truncated homolog (AlaS-like2)		 Saccharolobus solfataricus
TI:2287 None
 
YNE0_YEAST
SGD»
3.2
YNL040W Putative alanyl-tRNA editing protein alaX
(AlaX) (AlaXp) (AlaXp-II) (Alanyl-tRNA deacylase alaX)		 Saccharomyces cerevisiae
TI:4932 None
 
A7EQE7_SCLS1
VEuPathDB»
0.0
SS1G_07549 Threonyl/alanyl tRNA synthetase
SAD domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None
 
D8R0K8_SELML
EnsemblPlants»
0.0
SELMODRAFT_406072 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Selaginella moellendorffii
TI:88036 None
 
D8T1N1_SELML
EnsemblPlants»
0.0
SELMODRAFT_428079 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Selaginella moellendorffii
TI:88036 None
 
D8T1N4_SELML
EnsemblPlants»
0.0
SELMODRAFT_428080 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Selaginella moellendorffii
TI:88036 None
 
K3XL09_SETIT
EnsemblPlants»
0.0
Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Setaria italica
TI:4555 None
 
A0A1B6Q285_SORBI
EnsemblPlants»
0.0
SORBI_3003G094200 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Sorghum bicolor
TI:4558 None
 
A0A7M7SSR6_STRPU
EnsemblMetazoa»
0.0
Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A287BF30_PIG
Ensembl»
0.0
AARSD1 Alanyl-tRNA editing protein Aarsd1
(Alanyl-tRNA synthetase domain containing 1)		 Sus scrofa
TI:9823 None
 
B8CFA3_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_11693 Threonyl/alanyl tRNA synthetase
SAD domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
A0A061EP98_THECC
EnsemblPlants»
0.0
TCM_021201 Alanine-tRNA ligases,nucleic acid binding,ligases, forming aminoacyl-tRNA
and related compounds,nucleotide binding,ATP binding isoform 1		 Theobroma cacao
TI:3641 None
 
Q5JID2_THEKO
EnsemblBacteria»
0.0
TK0984 Alanyl-tRNA synthetase-related protein (Partial) Thermococcus kodakarensis
TI:311400 None
 
Q5JIQ8_THEKO
EnsemblBacteria»
0.0
TK1607 Alanyl-tRNA synthetase-related
protein (C-terminus)		 Thermococcus kodakarensis
TI:311400 None
 
Q9X249_THEMA
EnsemblBacteria»
0.0
TM_1726 Alanyl-tRNA synthetase-related protein Thermotoga maritima
TI:2336 None
 
D6W6E4_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_11516 Alanyl-tRNA editing protein Aarsd1-like Protein Tribolium castaneum
TI:7070 None
 
B3RQ03_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_20746 Threonyl/alanyl tRNA synthetase
SAD domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
B3RS86_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_54509 Threonyl/alanyl tRNA synthetase
SAD domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
A0A3B6E943_WHEAT
EnsemblPlants»
0.0
CFC21_033484 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Triticum aestivum
TI:4565 None
 
D8L9T6_WHEAT
EnsemblPlants»
0.0
CFC21_039046 TAA_ctg0954b.00310.1 TRAES_3BF041000090CFD_c1 Alanyl-tRNA synthetase, putative, expressed Triticum aestivum
TI:4565 None
 
I0JTV0_WHEAT
EnsemblPlants»
0.0
CFC21_045359 Alanyl-tRNA synthetase, putative, expressed Triticum aestivum
TI:4565 None
 
Q38ES2_TRYB2
VEuPathDB»
0.0
Tb09.160.4850 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Trypanosoma brucei
TI:5691 None
 
Q9KTW6_VIBCH
EnsemblBacteria»
0.0
VC_0764 Alanyl-tRNA synthetase-related protein Vibrio cholerae
TI:666 None
 
F6HE70_VITVI
EnsemblPlants»
0.0
VIT_05s0020g01470 Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Vitis vinifera
TI:29760 None
 
F6U4Q7_XENTR
Xenbase»
0.0
aarsd1 Alanyl-tRNA editing protein Aarsd1 isoform
X1 (Alanyl-tRNA synthetase domain containing 1)		 Xenopus tropicalis
TI:8364 None
   
Q6C730_YARLI
EnsemblFungi»
0.0
YALI0_E04246g YALI0E04246p Yarrowia lipolytica
TI:4952 None
 
B4FBL6_MAIZE
EnsemblPlants»
0.0
Alanyl-transfer RNA synthetases
family profile domain-containing protein		 Zea mays
TI:4577 None