Collated Gene Ontology terms

Biological process: hydrolase activity(2011, 2024) prenylcysteine methylesterase activity(2006, 2017, 2024) carboxylic ester hydrolase activity(2024) arylformamidase activity(2012, 2020, 2023, 2024) catalytic activity(2024) triglyceride lipase activity(2010, 2016, 2022, 2023, 2024) serine hydrolase activity(2008, 2022, 2024) short-chain carboxylesterase activity(2010, 2011, 2017) serine-type peptidase activity(2024) phosphate ion binding(2008, 2024)
hydrolase activity, acting on glycosyl bonds2024 lipase activity2011, 2024 acetylesterase activity2011, 2024 carboxylesterase activity2024 acetylalkylglycerol acetylhydrolase activity2024 steryl deacetylase activity2013, 2017 endo-1,4-beta-xylanase activity2024 deacetylase activity2024 calcium ion binding2024 transferase activity2024 sterol esterase activity2024 protein homodimerization activity2013 phospholipase C activity2010 phosphatidylcholine phospholipase C activity2024 metal ion binding2024 acylcarnitine hydrolase activity2019

Molecular function: tryptophan catabolic process to kynurenine2005, 2017, 2024 lipid catabolic process2024 tryptophan catabolic process2024 'de novo' NAD biosynthetic process from tryptophan2024 ether lipid metabolic process2020, 2024 xenobiotic metabolic process2008, 2024 proteolysis2024 xylan catabolic process2024 positive regulation of triglyceride catabolic process2017, 2024 sterol metabolic process2013, 2017
sterigmatocystin biosynthetic process2021, 2024 response to host immune response2010 biological process involved in interaction with host2010 response to toxic substance2013 response to acidic pH2018 response to abscisic acid2011 positive regulation of cell growth2024 modulation by symbiont of host innate immune response2023 meiotic cell cycle2024 low-density lipoprotein particle clearance2024 lipid metabolic process2024 growth of unicellular organism as a thread of attached cells2021 glycerolipid catabolic process2011 catabolic process2011 autophagy of mitochondrion2021 NAD biosynthetic process2024 GPI anchor biosynthetic process2021

Cellular component: membrane2006, 2008, 2014, 2022, 2024 endoplasmic reticulum membrane2011, 2015, 2017, 2024 Golgi membrane2011, 2017, 2024 endoplasmic reticulum2009, 2014, 2018, 2024 Golgi apparatus2024 cytoplasm2009, 2011, 2017, 2024 plasma membrane2010, 2014, 2024 nucleus2009, 2024 cytosol2008, 2009, 2024 extracellular region2012, 2024
phagocytic vesicle2006, 2009 mitochondrion2009, 2024 cell surface2024 lipid droplet2014 endoplasmic reticulum lumen2013 cell periphery2018 capsule2024

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 3/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 2/8 
Bacteria: 20/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
NCEH1_RAT
RGD»
3.0
Nceh1 Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Acetylalkylglycerol
acetylhydrolase) (2-acetyl MAGE hydrolase) (EC 3.1.1.71) (Arylacetamide deacetylase-like 1)		 Rattus norvegicus
TI:10116 None
 
NCEH1_HUMAN
Ensembl»
2.8
NCEH1 Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Acetylalkylglycerol
acetylhydrolase) (2-acetyl MAGE hydrolase) (EC 3.1.1.71) (Arylacetamide deacetylase-like 1)		 Homo sapiens
TI:9606 None
 
SAY1_YEAST
SGD»
3.2
SAY1 Steryl acetyl hydrolase 1 (EC 3.1.1.-) Saccharomyces cerevisiae
TI:4932 None
 
NCEH1_MOUSE
Ensembl»
3.2
Nceh1 Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Acetylalkylglycerol acetylhydrolase) (2-acetyl
MAGE hydrolase) (EC 3.1.1.71) (Arylacetamide deacetylase-like 1) (Chlorpyrifos oxon-binding protein) (CPO-BP)		 Mus musculus
TI:10090 None
 
F1NF25_CHICK
Ensembl»
0.5
NCEH1 Neutral cholesterol ester hydrolase 1 Gallus gallus
TI:9031 None
   
KFA_MOUSE
Ensembl»
1.7
Afmid Kynurenine formamidase (KFA) (KFase) (EC
3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)		 Mus musculus
TI:10090 None
 
M0RC77_RAT
RGD»
1.0
Afmid Kynurenine formamidase (KFA) (KFase) (EC
3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)		 Rattus norvegicus
TI:10116 None
   
ICME_ARATH
TAIR»
0.8
ICME Isoprenylcysteine alpha-carbonyl methylesterase ICME (EC
3.1.1.n2) (Isoprenylcysteine methylesterase) (Prenylcysteine methylesterase) (AtPCME)		 Arabidopsis thaliana
TI:3702 None
 
ICML2_ARATH
TAIR»
0.8
ICMEL2 Probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL2
(EC 3.1.1.n2) (Isoprenylcysteine methylesterase-like protein 2)		 Arabidopsis thaliana
TI:3702 None
 
KFA_DANRE
ZFIN»
0.5
afmid Kynurenine formamidase (KFA) (KFase) (EC
3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)		 Danio rerio
TI:7955 None
 
KFA_HUMAN
Ensembl»
0.5
AFMID Kynurenine formamidase (KFA) (KFase) (EC
3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)		 Homo sapiens
TI:9606 None
 
MU180_SCHPO
PomBase»
1.0
mug180 Putative steryl acetyl hydrolase mug81 (EC
3.1.1.-) (Meiotically up-regulated gene 180 protein)		 Schizosaccharomyces pombe
TI:4896 None
 
ICML1_ARATH
TAIR»
0.0
ICMEL1 Probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL1
(EC 3.1.1.n2) (Isoprenylcysteine methylesterase-like protein 1)		 Arabidopsis thaliana
TI:3702 None
 
A0A8V1AN76_CHICK
Ensembl»
0.0
AFMID Kynurenine formamidase (KFA) (KFase) (EC
3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)		 Gallus gallus
TI:9031 None
   
AES_ECOLI
EnsemblBacteria»
3.7
aes Acetyl esterase (EC 3.1.1.-) (EcE) Escherichia coli
TI:562 None
 
A0A8M1Q1F6_DANRE
CTD»
0.0
LOC797436 Neutral cholesterol ester hydrolase 1-like Danio rerio
TI:7955 None
   
E7F2W1_DANRE
ZFIN»
0.0
aadac Arylacetamide deacetylase Danio rerio
TI:7955 None
 
J3QPI0_MOUSE
Ensembl»
0.0
Aadacl2fm3 AADACL2 family member 3 Mus musculus
TI:10090 None
   
W4VSP6_MOUSE
Ensembl»
0.0
Aadacl2fm2 AADACL2 family member 2 Mus musculus
TI:10090 None
   
KFA_DROME
FlyBase»
1.3
KFase Kynurenine formamidase (KFA) (KFase) (EC
3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)		 Drosophila melanogaster
TI:7227 None
 
A0A8V0X9N3_CHICK
Ensembl»
0.0
AADAC Arylacetamide deacetylase Gallus gallus
TI:9031 None
   
Q94187_CAEEL
WormBase»
0.0
CELE_F16F9.4 F16F9.4 Alpha/beta hydrolase
fold-3 domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
YFZ3_SCHPO
PomBase»
0.0
SPAC1039.03 AB hydrolase superfamily
protein C1039.03 (EC 3.-.-.-)		 Schizosaccharomyces pombe
TI:4896 None
 
Q54R44_DICDI
dictyBase»
0.0
DDB_G0283413 Kynurenine formamidase (KFA) (KFase) (EC
3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)		 Dictyostelium discoideum
TI:44689 None
 
Q6DKF1_DANRE
ZFIN»
0.5
zgc:92416 Neutral cholesterol ester
hydrolase 1 (Zgc:92416)		 Danio rerio
TI:7955 None
 
M0R509_RAT
RGD»
0.0
Aadacl2fm2 AADACL2 family member 2 Rattus norvegicus
TI:10116 None
   
O62460_CAEEL
WormBase»
0.5
afmd-2 Alpha/beta hydrolase
fold-3 domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q19839_CAEEL
WormBase»
0.0
trcs-1 Alpha/beta hydrolase
fold-3 domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
YE76_SCHPO
PomBase»
0.0
SPAC4A8.06c AB hydrolase superfamily
protein C4A8.06c (EC 3.-.-.-)		 Schizosaccharomyces pombe
TI:4896 None
 
A0A8M1NVX1_DANRE
CTD»
0.0
aadacl4 Arylacetamide deacetylase-like 4 Danio rerio
TI:7955 None
   
A0A8V0ZGR1_CHICK
Ensembl»
0.0
AADACL3B Alpha/beta hydrolase
fold-3 domain-containing protein		 Gallus gallus
TI:9031 None
   
A0A8V0ZH30_CHICK
Ensembl»
0.0
Alpha/beta hydrolase
fold-3 domain-containing protein		 Gallus gallus
TI:9031 None
   
A0A8V0ZH66_CHICK
Ensembl»
0.0
AADACL4B Alpha/beta hydrolase
fold-3 domain-containing protein		 Gallus gallus
TI:9031 None
   
B1ASB3_MOUSE
Ensembl»
0.0
Aadacl4fm5 AADACL4 family member 5 Mus musculus
TI:10090 None
   
Q54K46_DICDI
dictyBase»
0.0
DDB_G0287609 Alpha/beta hydrolase
fold-3 domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
VSH5_DICDI
dictyBase»
0.0
cinB Vegetative-specific protein H5 Dictyostelium discoideum
TI:44689 None
 
A5PMM7_DANRE
ZFIN»
0.0
fj43c01 Si:dkey-193c22.1 (Uncharacterized
protein LOC567837)		 Danio rerio
TI:7955 None
 
B1AVU6_MOUSE
Ensembl»
0.0
Aadacl4fm4 AADACL4 family member 4 Mus musculus
TI:10090 None
   
M0R631_RAT
RGD»
0.0
Aadacl4fm2 Similar to novel protein similar to esterases Rattus norvegicus
TI:10116 None
   
Q54FB4_DICDI
dictyBase»
0.0
DDB_G0290975 Alpha/beta hydrolase
fold-3 domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q54L36_DICDI
dictyBase»
0.0
DDB_G0286925 Esterase/lipase/thioesterase
domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q54DJ5_DICDI
dictyBase»
0.0
DDB_G0292226 Uncharacterized protein Dictyostelium discoideum
TI:44689 None