Collated Gene Ontology terms

Biological process: fatty acyl-CoA hydrolase activity(2009, 2014, 2024, 2025) hydrolase activity(2025) hydrolase activity, acting on ester bonds(2025) deacylase activity(2025) acyl-CoA hydrolase activity(2025) thiolester hydrolase activity(2025) long-chain fatty acyl-CoA hydrolase activity(2025) identical protein binding(2025) nucleic acid binding(2025) metal ion binding(2025)
1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity2017

Molecular function: lipid metabolic process2025 negative regulation of cold-induced thermogenesis2018, 2025 protein homotetramerization2009, 2025 fatty acid biosynthetic process2025 acyl-CoA metabolic process2009

Cellular component: mitochondrion2009, 2018, 2024, 2025 nucleus2009, 2014, 2018, 2025 cytosol2009, 2015, 2017, 2025 cytoplasm2018, 2025 spindle2025 mitochondrial matrix2021, 2025 peroxisome2010, 2021, 2025 kinetoplast2018, 2025 nuclear lumen2018 ciliary plasm2018

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 11/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 2/8 
Bacteria: 5/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9VZZ6_DROME
FlyBase»
1.0
BcDNA:RE30174 CG16985 protein
(CG16985-PA) (GEO07616p1) (RE30174p)		 Drosophila melanogaster
TI:7227 None
 
ACO13_HUMAN
Ensembl»
2.6
ACOT13 Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Hotdog-fold thioesterase superfamily member 2) (Palmitoyl-CoA
hydrolase) (EC 3.1.2.2) (Thioesterase superfamily member 2) (THEM2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed]		 Homo sapiens
TI:9606 None
 
Q9M2E4_ARATH
TAIR»
0.5
T20K12.100 AT3g61200/T20K12_100 (Thioesterase
superfamily protein)		 Arabidopsis thaliana
TI:3702 None
 
Q9VZZ5_DROME
FlyBase»
1.0
Dmel\CG16986 GEO12033p1 (IP04654p) Drosophila melanogaster
TI:7227 None
 
Q9ZW37_ARATH
TAIR»
0.5
At2g29590 Acyl-coenzyme A thioesterase 13 (Hotdog-fold thioesterase
superfamily member 2) (Thioesterase superfamily member 2)		 Arabidopsis thaliana
TI:3702 None
 
ACO13_MOUSE
Ensembl»
3.6
Acot13 Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Hotdog-fold thioesterase
superfamily member 2) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (Thioesterase superfamily member 2) (THEM2)		 Mus musculus
TI:10090 None
 
P93828_ARATH
TAIR»
0.5
At1g04290 F19P19.27 protein
(Thioesterase superfamily protein)		 Arabidopsis thaliana
TI:3702 None
 
Q940V5_ARATH
TAIR»
0.5
At3g16175 Acyl-coenzyme A thioesterase 13 (Hotdog-fold thioesterase
superfamily member 2) (Thioesterase superfamily member 2)		 Arabidopsis thaliana
TI:3702 None
 
B3H4T3_ARATH
TAIR»
0.5
At1g52191 Acyl-coenzyme A thioesterase 13 (Hotdog-fold thioesterase
superfamily member 2) (Thioesterase superfamily member 2)		 Arabidopsis thaliana
TI:3702 None
 
C7G041_DICDI
dictyBase»
0.5
DDB_G0295733 Acyl-coenzyme A thioesterase 13 (Hotdog-fold thioesterase
superfamily member 2) (Thioesterase superfamily member 2)		 Dictyostelium discoideum
TI:44689 None
 
Q18187_CAEEL
WormBase»
0.5
C25H3.3 CELE_C25H3.3 Acyl-coenzyme A thioesterase 13 (Hotdog-fold thioesterase superfamily
member 2) (Palmitoyl-CoA hydrolase) (Thioesterase superfamily member 2)		 Caenorhabditis elegans
TI:6239 None
 
Q54HX1_DICDI
dictyBase»
0.5
DDB_G0289161 Acyl-coenzyme A thioesterase 13 (Hotdog-fold thioesterase
superfamily member 2) (Thioesterase superfamily member 2)		 Dictyostelium discoideum
TI:44689 None
 
Q86HX3_DICDI
dictyBase»
0.5
DDB_G0276419 Thioesterase superfamily protein Dictyostelium discoideum
TI:44689 None
 
Q8IG45_CAEEL
WormBase»
0.5
C25H3.14 CELE_C25H3.14 Acyl-coenzyme A thioesterase 13 (Hotdog-fold thioesterase superfamily
member 2) (Palmitoyl-CoA hydrolase) (Thioesterase superfamily member 2)		 Caenorhabditis elegans
TI:6239 None
 
YB22_SCHPO
PomBase»
2.5
SPBC31F10.02 Putative esterase C31F10.02 (EC 3.1.2.-) Schizosaccharomyces pombe
TI:4896 None
 
YLZ6_CAEEL
WormBase»
1.3
F42H10.6 Putative esterase F42H10.6 (EC 3.1.2.-) Caenorhabditis elegans
TI:6239 None
 
A0A8V0XVI6_CHICK
Ensembl»
0.5
Acyl-coenzyme A thioesterase 13 (Hotdog-fold thioesterase superfamily
member 2) (Palmitoyl-CoA hydrolase) (Thioesterase superfamily member 2)		 Gallus gallus
TI:9031 None
   
A0ACD6B6Q7_DANRE
ZFIN»
0.0
acot13 Acyl-coenzyme A thioesterase 13 isoform X1 Danio rerio
TI:7955 None 		     
D3ZA93_RAT
RGD»
2.5
Acot13 Acyl-CoA thioesterase 13 Rattus norvegicus
TI:10116 None