Collated Gene Ontology terms

Biological process: fatty acyl-CoA hydrolase activity(2001, 2021, 2024, 2025) hydrolase activity(2025) carboxylic ester hydrolase activity(2025) acetyl-CoA hydrolase activity(2005, 2024) nucleic acid binding(2025) long-chain fatty acyl-CoA hydrolase activity(2021) isomerase activity(2025) RNA binding(2025) ATP binding(2025)

Molecular function: acyl-CoA metabolic process2001, 2005, 2017, 2024, 2025 short-chain fatty acid metabolic process2021, 2025 long-chain fatty acid metabolic process2021, 2025 lipid metabolic process2025 fatty acid metabolic process2025

Cellular component: mitochondrion2001, 2005, 2009, 2018, 2024, 2025 mitochondrial matrix2015, 2021, 2023, 2024, 2025 mitochondrial inner membrane2025 peroxisome2008, 2025 chloroplast2018

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 9/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q6AWX1_ARATH
TAIR»
1.0
At2g30720 At2g30720 (Thioesterase/thiol ester
dehydrase-isomerase superfamily protein)		 Arabidopsis thaliana
TI:3702 None
 
Q9LK77_ARATH
TAIR»
1.0
At5g48370 At5g48370 (Similarity to acyl-CoA thioesterase)
(Thioesterase/thiol ester dehydrase-isomerase superfamily protein)		 Arabidopsis thaliana
TI:3702 None
 
O16725_CAEEL
WormBase»
1.0
CELE_T07D3.9 T07D3.9 HotDog ACOT-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q23044_CAEEL
WormBase»
1.0
CELE_T22B7.7 T22B7.7 HotDog ACOT-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q94245_CAEEL
WormBase»
1.0
CELE_F57F4.1 F57F4.1 HotDog ACOT-type domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A0AB40E6M3_DANRE
ZFIN»
0.0
acot9.2 Acyl-CoA thioesterase 9, tandem duplicate 2 Danio rerio
TI:7955 None
   
F1R961_DANRE
ZFIN»
1.0
acot9.1 Acyl-CoA thioesterase 9, tandem duplicate 1 Danio rerio
TI:7955 None
 
Q54D65_DICDI
dictyBase»
1.0
DDB_G0292458 RRM domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q54LP9_DICDI
dictyBase»
1.0
DDB_G0286507 RNA-binding region
RNP-1 domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q95TK5_DROME
FlyBase»
2.0
Dmel\CG1635 LD44914p Drosophila melanogaster
TI:7227 None
 
Q9V9W4_DROME
FlyBase»
2.0
Dmel\CG1774 GH08048p (Uncharacterized protein, isoform A)
(Uncharacterized protein, isoform B (EC 3.1.2.20))		 Drosophila melanogaster
TI:7227 None
 
Q9V9W5_DROME
FlyBase»
2.0
Dmel\CG1638 HotDog ACOT-type domain-containing protein Drosophila melanogaster
TI:7227 None
 
Q9VMA4_DROME
FlyBase»
2.0
Dmel\CG13771 Uncharacterized protein, isoform A (EC 3.1.2.20) Drosophila melanogaster
TI:7227 None
 
A0A8V0XCS8_CHICK
Ensembl»
1.0
ACOT9 Acyl-CoA thioesterase 9 Gallus gallus
TI:9031 None
   
ACOT9_HUMAN
Ensembl»
4.0
ACOT9 Acyl-coenzyme A thioesterase 9, mitochondrial (Acyl-CoA thioesterase 9)
(EC 3.1.2.-) (EC 3.1.2.2) (Acyl-CoA thioester hydrolase 9)		 Homo sapiens
TI:9606 None
 
ACO10_MOUSE
Ensembl»
2.7
Acot10 Acyl-coenzyme A thioesterase 10, mitochondrial (Acyl-CoA thioesterase 10) (EC
3.1.2.-) (Mitochondrial 48 kDa acyl-CoA thioester hydrolase 2) (Mt-ACT48.2)		 Mus musculus
TI:10090 None
 
ACOT9_MOUSE
Ensembl»
5.8
Acot9 Acyl-coenzyme A thioesterase 9, mitochondrial (Acyl-CoA thioesterase 9) (EC 3.1.2.-) (EC 3.1.2.2) (Acyl coenzyme A thioester hydrolase
2) (MTE-2) (Acyl-CoA thioester hydrolase 9) (Mitochondrial 48 kDa acyl-CoA thioester hydrolase 1) (MT-ACT48.1) (Protein U8) (p48)		 Mus musculus
TI:10090 None
 
F7ETS0_RAT
RGD»
4.0
Acot9 Acyl-CoA thioesterase 9 Rattus norvegicus
TI:10116 None