Collated Gene Ontology terms

Biological process: rRNA (cytosine-N4-)-methyltransferase activity(2009, 2022, 2024, 2025) methyltransferase activity(2014, 2025) transferase activity(2025) protein homodimerization activity(2012)

Molecular function: rRNA base methylation2009, 2022, 2024, 2025 methylation2025 rRNA processing2025 mitochondrial small ribosomal subunit assembly2025

Cellular component: cytoplasm2009, 2017, 2025 mitochondrial matrix2024, 2025 mitochondrion2014, 2022, 2024, 2025 chloroplast2018, 2020, 2025 plasma membrane2010 cytosol2014

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 35/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A1D5PLE8_CHICK
Ensembl»
1.0
METTL15 12S rRNA N(4)-cytidine methyltransferase METTL15 (Methyltransferase
5 domain-containing protein 1) (Methyltransferase-like protein 15)		 Gallus gallus
TI:9031 None
   
F7F172_RAT
RGD»
2.5
Mettl15 12S rRNA N(4)-cytidine methyltransferase METTL15 (Methyltransferase
5 domain-containing protein 1) (Methyltransferase-like protein 15)		 Rattus norvegicus
TI:10116 None
   
ME15P_HUMAN
AG»
1.0
METTL15P1 Putative methyltransferase-like protein 15P1 (EC 2.1.1.-) (Methyltransferase 5
domain-containing protein 2) (Methyltransferase-like protein 15 pseudogene 1)		 Homo sapiens
TI:9606 None
 
MET15_DROME
FlyBase»
2.5
CG14683 Probable methyltransferase-like protein
15 homolog (EC 2.1.1.-)		 Drosophila melanogaster
TI:7227 None
 
MET15_HUMAN
Ensembl»
3.4
METTL15 12S rRNA N(4)-cytidine methyltransferase METTL15 (12S rRNA m4C methyltransferase)
(EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1) (Methyltransferase-like protein 15)		 Homo sapiens
TI:9606 None
 
MET15_MOUSE
Ensembl»
1.5
Mettl15 12S rRNA N(4)-cytidine methyltransferase METTL15 (12S rRNA m4C methyltransferase)
(EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1) (Methyltransferase-like protein 15)		 Mus musculus
TI:10090 None
 
Q54PT4_DICDI
dictyBase»
1.0
DDB_G0284343 Uncharacterized protein Dictyostelium discoideum
TI:44689 None
 
Q9LEU9_ARATH
TAIR»
1.0
CMAL AT5g10910/T30N20_180 (MraW
methylase family protein)		 Arabidopsis thaliana
TI:3702 None
 
RSMH_ECOLI
EnsemblBacteria»
3.4
rsmH Ribosomal RNA small subunit methyltransferase H (EC
2.1.1.199) (16S rRNA m(4)C1402 methyltransferase) (rRNA (cytosine-N(4)-)-methyltransferase RsmH)		 Escherichia coli
TI:562 None