Collated Gene Ontology terms

Biological process: glucosaminyl-phosphatidylinositol O-acyltransferase activity(2011, 2013, 2014, 2024, 2025) O-acyltransferase activity(2020, 2025) acyltransferase activity(2025) transferase activity(2025) zinc ion binding(2025) ubiquitin protein ligase activity(2025) protein dimerization activity(2025) nucleic acid binding(2025) metal ion binding(2025) kinase activity(2025)

Molecular function: GPI anchor biosynthetic process2005, 2011, 2013, 2014, 2025 GPI anchor metabolic process2014, 2025 protein localization to plasma membrane2014, 2025 protein transport2025 meiotic cell cycle2025 DNA-templated transcription2025

Cellular component: membrane2022, 2025 endoplasmic reticulum2018, 2025 endoplasmic reticulum membrane2005, 2013, 2025 nucleus2025 nuclear outer membrane-endoplasmic reticulum membrane network2018 mitochondrion2018 endomembrane system2025

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
PIGW_MOUSE
Ensembl»
4.0
Pigw Glucosaminyl-phosphatidylinositol-acyltransferase PIGW (GlcN-PI-acyltransferase) (EC 2.3.-.-)
(Phosphatidylinositol-glycan biosynthesis class W protein) (PIG-W)		 Mus musculus
TI:10090 None
 
PIGW_HUMAN
Ensembl»
5.6
PIGW Glucosaminyl-phosphatidylinositol-acyltransferase PIGW (GlcN-PI-acyltransferase) (EC 2.3.-.-)
(Phosphatidylinositol-glycan biosynthesis class W protein) (PIG-W)		 Homo sapiens
TI:9606 None
 
GWT1_YEAST
SGD»
3.4
GWT1 GPI-anchored wall transfer
protein 1 (EC 2.3.-.-)		 Saccharomyces cerevisiae
TI:4932 None
 
PIGW_RAT
RGD»
3.6
Pigw Glucosaminyl-phosphatidylinositol-acyltransferase PIGW (GlcN-PI-acyltransferase) (EC 2.3.-.-)
(Phosphatidylinositol-glycan biosynthesis class W protein) (PIG-W)		 Rattus norvegicus
TI:10116 None
 
A0A3Q7HTU6_SOLLC
EnsemblPlants»
0.0
RING-type E3 ubiquitin transferase (EC 2.3.2.27) Solanum lycopersicum
TI:4081 None
   
PIGW_BOVIN
CTD»
0.0
PIGW Glucosaminyl-phosphatidylinositol-acyltransferase PIGW (GlcN-PI-acyltransferase) (EC 2.3.-.-)
(Phosphatidylinositol-glycan biosynthesis class W protein) (PIG-W)		 Bos taurus
TI:9913 None
 
GWT1_SCHPO
PomBase»
2.6
gwt1 GPI-anchored wall transfer protein 1 (EC
2.3.-.-) (Meiotically up-regulated gene 59 protein)		 Schizosaccharomyces pombe
TI:4896 None
 
A0A1L8H704_XENLA
Xenbase»
0.0
pigw.S Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Xenopus laevis
TI:8355 None
   
GWT1_CANAL
EnsemblFungi»
0.0
GWT1 GPI-anchored wall transfer
protein 1 (EC 2.3.-.-)		 Candida albicans
TI:5476 None
 
Q9VQB8_DROME
FlyBase»
2.0
PIG-Wa Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Drosophila melanogaster
TI:7227 None
 
Q9W096_DROME
FlyBase»
2.0
PIG-Wb Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Drosophila melanogaster
TI:7227 None
 
GWT1_ASPFU
EnsemblFungi»
0.0
gwt1 GPI-anchored wall transfer
protein 1 (EC 2.3.-.-)		 Aspergillus fumigatus
TI:746128 None
 
A0A1S4AUD8_TOBAC
euHCVdb»
0.0
LOC107801482 Uncharacterized protein At4g17910 Nicotiana tabacum
TI:4097 None
   
A0A1U8LA09_GOSHI
euHCVdb»
0.0
LOC107924155 Uncharacterized protein LOC107924155 isoform
X1 (Uncharacterized protein isoform X1)		 Gossypium hirsutum
TI:3635 None
   
A0A1U8N0G3_GOSHI
euHCVdb»
0.0
LOC107942196 Uncharacterized protein At4g17910 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A287AP94_PIG
Ensembl»
0.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Sus scrofa
TI:9823 None
   
A0A8I3PZQ5_CANLF
Ensembl»
0.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Canis lupus
TI:9612 None
   
A0A8V1AB48_CHICK
Ensembl»
1.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Gallus gallus
TI:9031 None
   
A0A9R0IPX4_SPIOL
neXtProt»
0.0
LOC110791962 Uncharacterized protein At4g17910 Spinacia oleracea
TI:3562 None
   
B6JUW9_SCHJY
TubercuList»
0.0
gwt1 GPI-anchored wall transfer protein (EC 2.3.-.-) Schizosaccharomyces japonicus
TI:4897 None
 
F1N3J6_BOVIN
Ensembl»
0.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Bos taurus
TI:9913 None
   
F6T417_ORNAN
Ensembl»
0.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Ornithorhynchus anatinus
TI:9258 None
   
F6Z393_HORSE
Ensembl»
0.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Equus caballus
TI:9796 None
   
F7HT11_MACMU
Ensembl»
0.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Macaca mulatta
TI:9544 None
 
G3QY46_GORGO
Ensembl»
0.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Gorilla gorilla
TI:9593 None
 
GWT1_YARLI
EnsemblFungi»
0.0
GWT1 GPI-anchored wall transfer
protein 1 (EC 2.3.-.-)		 Yarrowia lipolytica
TI:4952 None
 
H2R9M3_PANTR
Ensembl»
0.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Pan troglodytes
TI:9598 None
 
A0A1S4H0P4_ANOGA
EnsemblMetazoa»
0.0
Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Anopheles gambiae
TI:7165 None
 
A0A2A6B3R0_PRIPA
EnsemblMetazoa»
0.0
WBGene00099647 Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Pristionchus pacificus
TI:54126 None
   
A0A7M7PJQ9_STRPU
EnsemblMetazoa»
0.0
Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7RD88_STRPU
EnsemblMetazoa»
0.0
Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A9J7MCB8_BRAFL
euHCVdb»
0.0
LOC118431474 Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Branchiostoma floridae
TI:7739 None
   
A0ABM3BLH4_GOSHI
euHCVdb»
0.0
LOC121228917 GPI-anchored wall transfer protein 1 Gossypium hirsutum
TI:3635 None
   
A7F332_SCLS1
TubercuList»
0.0
SS1G_12330 GPI-anchored wall transfer protein (EC 2.3.-.-) Sclerotinia sclerotiorum
TI:5180 None
 
A7SB56_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g209576 Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Nematostella vectensis
TI:45351 None
 
B3S3N6_TRIAD
CTD»
0.0
TRIADDRAFT_28955 Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Trichoplax adhaerens
TI:10228 None
 
D6RYD7_CAEEL
WormBase»
1.0
pigw-1 Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Caenorhabditis elegans
TI:6239 None
 
D6WM59_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_14480 Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Tribolium castaneum
TI:7070 None
 
E3K5G3_PUCGT
TubercuList»
0.0
PGTG_05770 GPI-anchored wall transfer protein (EC 2.3.-.-) Puccinia graminis
TI:5297 None
 
E9G6I2_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_209372 Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Daphnia pulex
TI:6669 None
 
F1QAR3_DANRE
ZFIN»
1.0
pigw Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Danio rerio
TI:7955 None
 
F6QUR5_XENTR
Xenbase»
0.0
pigw Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Xenopus tropicalis
TI:8364 None
   
F7A2R6_CIOIN
Ensembl»
0.0
Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Ciona intestinalis
TI:7719 None
 
GWT1_CRYD1
EnsemblFungi»
0.0
GWT1 GPI-anchored wall transfer
protein 1 (EC 2.3.-.-)		 Cryptococcus deneoformans
TI:40410 None
 
GWT1_EMENI
EnsemblFungi»
0.0
gwt1 GPI-anchored wall transfer
protein 1 (EC 2.3.-.-)		 Emericella nidulans
TI:162425 None
 
GWT1_EREGS
EnsemblFungi»
0.0
GWT1 GPI-anchored wall transfer
protein 1 (EC 2.3.-.-)		 Eremothecium gossypii
TI:33169 None
 
GWT1_NEUCR
EnsemblFungi»
0.0
gwt1 GPI-anchored wall transfer
protein 1 (EC 2.3.-.-)		 Neurospora crassa
TI:5141 None
 
H2M6S7_ORYLA
Ensembl»
0.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Oryzias latipes
TI:8090 None
   
PIGW_DICDI
dictyBase»
1.0
pigw Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Dictyostelium discoideum
TI:44689 None
 
W5NLM0_LEPOC
Ensembl»
0.0
Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Lepisosteus oculatus
TI:7918 None
 
A0A1U8NTE3_GOSHI
euHCVdb»
0.0
LOC107951639 Serine/threonine-protein kinase TOR isoform X2 Gossypium hirsutum
TI:3635 None
   
A0A251VGU0_HELAN
euHCVdb»
0.0
HannXRQ_Chr02g0049971 HanXRQr2_Chr02g0073861 Phosphatidylinositol anchor biosynthesis protein PIGW/GWT1
(Putative transferase, transferring acyl groups)		 Helianthus annuus
TI:4232 None
 
A8XW09_CAEBR
WormBase»
0.0
pigw-1 Protein CBR-HPO-20 Caenorhabditis briggsae
TI:6238 None
 
K7VH76_MAIZE
EnsemblPlants»
0.0
LOC100273831 Transferase transferring acyl groups Zea mays
TI:4577 None
 
Y4791_ARATH
TAIR»
1.0
At4g17910 Uncharacterized protein At4g17910 Arabidopsis thaliana
TI:3702 None
 
A0A078JJS2_BRANA
euHCVdb»
0.0
BnaA03g56790D (rape) hypothetical
protein (BnaA03g56790D protein)		 Brassica napus
TI:3708 None
 
A0A0A0L556_CUCSA
neXtProt»
0.0
Csa_3G009480 GPI-anchored wall transfer protein Cucumis sativus
TI:3659 None
 
A0A0K9NZ69_ZOSMR
neXtProt»
0.0
ZOSMA_49G00930 GPI-anchored wall transfer protein Zostera marina
TI:29655 None
 
A0A0R0L8L8_SOYBN
EnsemblPlants»
0.0
GLYMA_01G095400 GPI-anchored wall transfer protein 1 Glycine max
TI:3847 None
 
A0A1B6QMY4_SORBI
euHCVdb»
0.0
SORBI_3001G356100 Transferase transferring acyl groups Sorghum bicolor
TI:4558 None
 
A0A1U8GVU6_CAPAN
euHCVdb»
0.0
T459_00879 GPI-anchored wall transfer protein Capsicum annuum
TI:4072 None
 
A0A1U8HP20_GOSHI
euHCVdb»
0.0
LOC107886330 Uncharacterized protein At4g17910 isoform X1
(Uncharacterized protein At4g17910-like isoform X1)		 Gossypium hirsutum
TI:3635 None
   
A0A1U8KLD8_GOSHI
neXtProt»
0.0
LOC107916698 Uncharacterized protein At4g17910 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1Y1I9B8_KLENI
euHCVdb»
0.0
KFL_002960070 Phosphatidylinositol glycan class W Klebsormidium nitens
TI:105231 None
 
A0A251P346_PRUPE
euHCVdb»
0.0
PRUPE_5G033200 GPI-anchored wall transfer protein Prunus persica
TI:3760 None
 
A0A2I4DNW0_JUGRE
neXtProt»
0.0
LOC108982023 Uncharacterized protein At4g17910 Juglans regia
TI:51240 None
   
A0A2K2B486_POPTR
euHCVdb»
0.0
POPTR_003G093300 GPI-anchored wall transfer protein Populus trichocarpa
TI:3694 None
 
A0A2K3D0T6_CHLRE
euHCVdb»
0.0
CHLRE_13g587200v5 Phosphatidylinositol-glycan biosynthesis
class W protein		 Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6X8P9_MARPO
euHCVdb»
0.0
MARPO_0029s0019 GPI-anchored wall transfer protein Marchantia polymorpha
TI:3197 None
 
A0A3B6ASK0_WHEAT
EnsemblPlants»
0.0
GPI-anchored wall transfer protein 1 Triticum aestivum
TI:4565 None
   
A0A3B6B1U1_WHEAT
EnsemblPlants»
0.0
LOC123189805 GPI-anchored wall transfer protein Triticum aestivum
TI:4565 None
   
A0A3B6C0F0_WHEAT
EnsemblPlants»
0.0
LOC123043733 GPI-anchored wall transfer protein Triticum aestivum
TI:4565 None
   
A0A3B6CC58_WHEAT
EnsemblPlants»
0.0
LOC123046036 GPI-anchored wall transfer protein Triticum aestivum
TI:4565 None
   
A0A3B6D7G8_WHEAT
EnsemblPlants»
0.0
LOC123051595 GPI-anchored wall transfer protein Triticum aestivum
TI:4565 None
   
A0A3B6DHD0_WHEAT
EnsemblPlants»
0.0
GPI-anchored wall transfer protein Triticum aestivum
TI:4565 None
   
A0A804JFE5_MUSAM
EnsemblPlants»
0.0
GPI-anchored wall transfer protein Musa acuminata
TI:4641 None
   
A0A804LL11_MAIZE
EnsemblPlants»
0.0
LOC100216561 Transferase transferring acyl groups Zea mays
TI:4577 None
   
A0A9R1V5V0_LACSA
euHCVdb»
0.0
LSAT_V11C600299310 GPI-anchored wall transfer protein Lactuca sativa
TI:4236 None
 
A0ABM2YSH4_GOSHI
euHCVdb»
0.0
LOC107888712 Uncharacterized protein At4g17910 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0ABM2ZVE8_GOSHI
euHCVdb»
0.0
LOC107939771 Uncharacterized protein At4g17910 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0ABM3AER5_GOSHI
neXtProt»
0.0
LOC107887877 Uncharacterized protein At4g17910 Gossypium hirsutum
TI:3635 None
   
A0ABM3BJH4_GOSHI
neXtProt»
0.0
LOC107917440 GPI-anchored wall transfer protein 1 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0ABM3BMG2_GOSHI
euHCVdb»
0.0
LOC107925534 Uncharacterized protein isoform X1 Gossypium hirsutum
TI:3635 None
   
A9SNV8_PHYPA
EnsemblPlants»
0.0
LOC112292795 GPI-anchored wall transfer protein Physcomitrium patens
TI:3218 None
 
B7PQD7_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW006280 Phosphatidylinositol-glycan biosynthesis class
W protein, putative		 Ixodes scapularis
TI:6945 None
 
B9S6K9_RICCO
neXtProt»
0.0
RCOM_1109320 GPI-anchored wall transfer protein, putative Ricinus communis
TI:3988 None
 
C4M4K5_ENTH1
TubercuList»
0.0
EHI_031230 GPI-anchored wall transfer protein Entamoeba histolytica
TI:5759 None
 
C6KSZ4_PLAF7
TubercuList»
0.0
PF3D7_0615300 GPI-anchored wall transfer protein 1, putative Plasmodium falciparum
TI:5833 None
 
D3KHE6_GIAIC
TubercuList»
0.0
GL50803_0086933 Uncharacterized protein Giardia intestinalis
TI:5741 None
 
D8R2Y0_SELML
euHCVdb»
0.0
SELMODRAFT_406788 GPI-anchored wall transfer protein Selaginella moellendorffii
TI:88036 None
 
D8RYJ4_SELML
euHCVdb»
0.0
SELMODRAFT_415900 GPI-anchored wall transfer protein Selaginella moellendorffii
TI:88036 None
 
F0ZA87_DICPU
TubercuList»
0.0
DICPUDRAFT_45375 Phosphatidylinositol-glycan biosynthesis
class W protein		 Dictyostelium purpureum
TI:5786 None
 
F4NWA8_BATDJ
euHCVdb»
0.0
BATDEDRAFT_22956 GPI-anchored wall transfer protein 1 Batrachochytrium dendrobatidis
TI:109871 None
 
G7IAL1_MEDTR
EnsemblPlants»
0.0
MTR_1g100910 GPI-anchored wall transfer protein Medicago truncatula
TI:3880 None
 
G7LH17_MEDTR
EnsemblPlants»
0.0
MTR_8g066760 GPI-anchored wall transfer protein Medicago truncatula
TI:3880 None
 
H3GEA6_PHYRM
EnsemblProtists»
0.0
GPI-anchored wall transfer protein Phytophthora ramorum
TI:164328 None
 
I1H512_BRADI
EnsemblPlants»
0.0
LOC100833614 GPI-anchored wall transfer protein Brachypodium distachyon
TI:15368 None
 
K4ALX8_SETIT
EnsemblPlants»
0.0
LOC101763918 GPI-anchored wall transfer protein Setaria italica
TI:4555 None
 
K7L971_SOYBN
EnsemblPlants»
0.0
LOC100811353 GPI-anchored wall transfer protein Glycine max
TI:3847 None
 
M0XD49_HORVV
EnsemblPlants»
0.0
LOC123427328 GPI-anchored wall transfer protein Hordeum vulgare
TI:4513 None
   
M4C859_BRACM
EnsemblPlants»
0.0
GPI-anchored wall transfer protein Brassica campestris
TI:3711 None
   
Q10KM5_ORYSJ
neXtProt»
0.0
LOC_Os03g26090 Os03g0378200 GWT1 family protein, expressed (Os03g0378200
protein) (cDNA clone:J023042E14, full insert sequence)		 Oryza sativa
TI:4530 None
 
T1FFJ6_HELRO
EnsemblMetazoa»
0.0
20207595 Phosphatidylinositol-glycan biosynthesis
class W protein		 Helobdella robusta
TI:6412 None
 
W1P2C9_AMBTC
neXtProt»
0.0
AMTR_s00002p00198580 GPI-anchored wall transfer protein Amborella trichopoda
TI:13333 None
 
A0A7U2FD50_PHANO
TubercuList»
0.0
JI435_141630 GPI-anchored wall transfer protein (EC 2.3.-.-) Phaeosphaeria nodorum
TI:13684 None
 
A0ABI8A3E6_FELCA
Ensembl»
0.0
PIGW Phosphatidylinositol-glycan biosynthesis class
W protein (EC 2.3.-.-)		 Felis catus
TI:9685 None
   
A0A022QE76_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a0219402mg Uncharacterized protein Erythranthe guttata
TI:4155 None
 
A0A022QIA2_ERYGU
neXtProt»
0.0
MIMGU_mgv1a0219401mg GPI-anchored wall transfer protein 1 Erythranthe guttata
TI:4155 None
 
A0A022RLC5_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a0224402mg Uncharacterized protein Erythranthe guttata
TI:4155 None
 
A0A022RPE9_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a0224401mg Uncharacterized protein Erythranthe guttata
TI:4155 None
 
A0A061G280_THECC
neXtProt»
0.0
TCM_015693 GPI-anchored wall transfer protein isoform 4 Theobroma cacao
TI:3641 None
 
A0A067D668_CITSI
euHCVdb»
0.0
CISIN_1g0428391mg Uncharacterized protein Citrus sinensis
TI:2711 None
 
A0A067DH17_CITSI
euHCVdb»
0.0
CISIN_1g0428392mg GPI-anchored wall transfer protein 1 Citrus sinensis
TI:2711 None
 
A0A1U7YT72_NELNU
euHCVdb»
0.0
LOC104585626 Uncharacterized protein At4g17910 isoform X2 Nelumbo nucifera
TI:4432 None
   
M1BH51_SOLTU
EnsemblPlants»
0.0
GPI-anchored wall transfer protein Solanum tuberosum
TI:4113 None
   
M1BHA6_SOLTU
EnsemblPlants»
0.0
GPI-anchored wall transfer protein Solanum tuberosum
TI:4113 None