Collated Gene Ontology terms

Biological process: tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity(2015, 2021, 2025) methyltransferase activity(2025) transferase activity(2025) RNA binding(2025) tRNA binding(2015) protein kinase activity(2025) nucleotide binding(2025) ATP binding(2025) protein tyrosine kinase activity(2025) protein serine/threonine kinase activity(2025)
kinase activity2025

Molecular function: methylation2025 tRNA processing2025 tRNA methylation2014, 2015, 2025

Cellular component: nucleoplasm2025 cytoplasm2025 chloroplast2018

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 7/8 
Bacteria: 15/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
TRMO_MOUSE
Ensembl»
2.5
Trmo tRNA (adenine(37)-N6)-methyltransferase (EC
2.1.1.-) (tRNA methyltransferase O)		 Mus musculus
TI:10090 None
 
TRMO_RAT
RGD»
2.5
Trmo tRNA (adenine(37)-N6)-methyltransferase (EC
2.1.1.-) (tRNA methyltransferase O)		 Rattus norvegicus
TI:10116 None
 
TRMO_ECOLI
EnsemblBacteria»
2.9
trmO tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA
(m6t6A37) methyltransferase) (tRNA methyltransferase O)		 Escherichia coli
TI:562 None
 
TRMO_HAEIN
EnsemblBacteria»
0.0
trmO tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA
(m6t6A37) methyltransferase) (tRNA methyltransferase O)		 Haemophilus influenzae
TI:727 None
 
TRMO_HUMAN
Ensembl»
2.1
TRMO tRNA (adenine(37)-N6)-methyltransferase (EC
2.1.1.-) (tRNA methyltransferase O)		 Homo sapiens
TI:9606 None
 
A0A3Q7IQB0_SOLLC
EnsemblPlants»
0.0
non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Solanum lycopersicum
TI:4081 None
   
A5D7V4_BOVIN
Ensembl»
0.0
TRMO tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Bos taurus
TI:9913 None
 
F6TYQ5_MONDO
Ensembl»
0.0
TRMO tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Monodelphis domestica
TI:13616 None
   
F6ZUI3_HORSE
Ensembl»
0.0
TRMO tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Equus caballus
TI:9796 None
   
G3QXH1_GORGO
Ensembl»
0.0
TRMO tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Gorilla gorilla
TI:9593 None
 
H2QXJ5_PANTR
Ensembl»
0.0
TRMO tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Pan troglodytes
TI:9598 None
 
A0A2U2GZV9_YERPE
neXtProt»
0.0
YPO1069 tRNA (adenine(37)-N6)-methyltransferase (tRNA (m6t6A37)
methyltransferase) (tRNA methyltransferase O)		 Yersinia pestis
TI:632 None
 
Q8ECJ1_SHEON
neXtProt»
0.0
yaeB tRNA (adenine(37)-N6)-methyltransferase (tRNA (m6t6A37)
methyltransferase) (tRNA methyltransferase O)		 Shewanella oneidensis
TI:70863 None
 
Q8ZRN2_SALTY
neXtProt»
0.0
yaeB tRNA (adenine(37)-N6)-methyltransferase (tRNA (m6t6A37)
methyltransferase) (tRNA methyltransferase O)		 Salmonella typhimurium
TI:28901 None
 
Q9KTM6_VIBCH
EnsemblBacteria»
0.0
VC_0876 tRNA (adenine(37)-N6)-methyltransferase (tRNA (m6t6A37)
methyltransferase) (tRNA methyltransferase O)		 Vibrio cholerae
TI:666 None
 
A9V4U4_MONBE
euHCVdb»
0.0
MONBRDRAFT_33342 Non-specific protein-tyrosine kinase Monosiga brevicollis
TI:81824 None
 
B0BLU9_XENTR
Xenbase»
0.0
trmo tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Xenopus tropicalis
TI:8364 None
 
H2LS45_ORYLA
Ensembl»
0.0
TRMO tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Oryzias latipes
TI:8090 None
   
Q5EAT7_XENLA
Xenbase»
0.0
trmo.L tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Xenopus laevis
TI:8355 None
 
R4GEK9_DANRE
ZFIN»
0.5
trmo tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Danio rerio
TI:7955 None
 
W5N219_LEPOC
Ensembl»
0.0
tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Lepisosteus oculatus
TI:7918 None
 
A0A8I3RY66_CANLF
Ensembl»
0.0
TRMO tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Canis lupus
TI:9612 None
   
F7H2E2_MACMU
Ensembl»
0.0
TRMO tRNA (adenine(37)-N6)-methyltransferase
(tRNA methyltransferase O)		 Macaca mulatta
TI:9544 None
 
Q6NMB4_ARATH
TAIR»
0.5
At4g28015 At4g28020 At4g28020 (tRNA-thr(GGU)
m(6)t(6)A37 methyltransferase)		 Arabidopsis thaliana
TI:3702 None
 
RCSF1_PSEAE
PharmGKB»
0.0
rcsF Putative S-adenosylmethionine-dependent methyltransferase
RcsF (EC 2.1.1.-)		 Pseudomonas aeruginosa
TI:287 None
 
A1Z759_DROME
FlyBase»
1.5
CG12822-PA Uncharacterized protein, isoform A Drosophila melanogaster
TI:7227 None
 
G7JE89_MEDTR
EnsemblPlants»
0.0
11425476 YaeB/AF-0241 family methyltransferase, putative Medicago truncatula
TI:3880 None
 
Q57XM2_TRYB2
TubercuList»
0.0
Tb07.22O10.610 TsaA-like domain-containing protein Trypanosoma brucei
TI:5691 None
 
A0A022R239_ERYGU
neXtProt»
0.0
MIMGU_mgv1a010900mg TsaA-like domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A061GR62_THECC
euHCVdb»
0.0
TCM_038609 Uncharacterized protein isoform 1 Theobroma cacao
TI:3641 None
 
A0A067F8B7_CITSI
euHCVdb»
0.0
CISIN_1g016676mg TsaA-like domain-containing protein Citrus sinensis
TI:2711 None
 
A0A078FMZ5_BRANA
euHCVdb»
0.0
BnaA08g13900D (rape) hypothetical
protein (BnaA08g13900D protein)		 Brassica napus
TI:3708 None
 
A0A0A0LTM6_CUCSA
euHCVdb»
0.0
Csa_1G295140 TsaA-like domain-containing protein Cucumis sativus
TI:3659 None
 
A0A0K9P1Q7_ZOSMR
neXtProt»
0.0
ZOSMA_438G00030 Nef-associated protein Zostera marina
TI:29655 None
 
A0A0Q3ES53_BRADI
EnsemblPlants»
0.0
LOC100834955 TsaA-like domain-containing protein Brachypodium distachyon
TI:15368 None
 
A0A1S3Y240_TOBAC
euHCVdb»
0.0
LOC107771347 Uncharacterized protein
LOC107771347 (tRNA (Adenine(37)-N6)-methyltransferase)		 Nicotiana tabacum
TI:4097 None
   
A0A1S3Y4E1_TOBAC
euHCVdb»
0.0
LOC107772059 Uncharacterized protein LOC107772059 isoform X1 Nicotiana tabacum
TI:4097 None
   
A0A1U8AL93_NELNU
euHCVdb»
0.0
LOC104601467 Uncharacterized protein LOC104601467 Nelumbo nucifera
TI:4432 None
   
A0A1U8F1U9_CAPAN
euHCVdb»
0.0
T459_29646 Nef-associated protein 1 Capsicum annuum
TI:4072 None
 
A0A1U8JR64_GOSHI
euHCVdb»
0.0
LOC107909649 tRNA (Adenine(37)-N6)-methyltransferase
isoform X1		 Gossypium hirsutum
TI:3635 None
   
A0A1U8KWM8_GOSHI
euHCVdb»
0.0
LOC107920117 tRNA (Adenine(37)-N6)-methyltransferase
isoform X1		 Gossypium hirsutum
TI:3635 None
   
A0A1W0W5A6_SORBI
euHCVdb»
0.0
SORBI_3002G208400 TsaA-like domain-containing protein Sorghum bicolor
TI:4558 None
 
A0A1Y1IMV6_KLENI
euHCVdb»
0.0
KFL_006850030 TsaA-like domain-containing protein Klebsormidium nitens
TI:105231 None
 
A0A251QUQ9_PRUPE
euHCVdb»
0.0
PRUPE_1G095000 TsaA-like domain-containing protein Prunus persica
TI:3760 None
 
A0A251UN31_HELAN
euHCVdb»
0.0
HannXRQ_Chr05g0136551 HanXRQr2_Chr05g0200201 TrmO-like domain, YaeB-like superfamily protein Helianthus annuus
TI:4232 None
 
A0A2I4FHW0_JUGRE
euHCVdb»
0.0
LOC108998917 Uncharacterized protein LOC108998917 isoform X1 Juglans regia
TI:51240 None
   
A0A2K3CXE9_CHLRE
euHCVdb»
0.0
CHLRE_14g613450v5 TsaA-like domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6WZZ6_MARPO
euHCVdb»
0.0
MARPO_0045s0079 TsaA-like domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A3B6KGA1_WHEAT
EnsemblPlants»
0.0
LOC123103814 TsaA-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6LKW7_WHEAT
EnsemblPlants»
0.0
LOC123112050 TsaA-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6LMQ9_WHEAT
EnsemblPlants»
0.0
LOC123112051 TsaA-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6MQS9_WHEAT
EnsemblPlants»
0.0
LOC123121586 TsaA-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A7I4FVZ5_PHYPA
EnsemblPlants»
0.0
LOC112286836 TsaA-like domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A7M7SUU9_STRPU
EnsemblMetazoa»
0.0
TsaA-like domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A804KAP5_MUSAM
EnsemblPlants»
0.0
GSMUA_86420.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A804Q980_MAIZE
EnsemblPlants»
0.0
LOC100191276 TsaA-like domain-containing protein Zea mays
TI:4577 None
   
A0A8I6XFR3_HORVV
EnsemblPlants»
0.0
LOC123397900 TsaA-like domain-containing protein Hordeum vulgare
TI:4513 None
   
A0A9J7KNE8_BRAFL
neXtProt»
0.0
LOC118409937 tRNA (Adenine(37)-N6)-methyltransferase-like Branchiostoma floridae
TI:7739 None
   
A0A9R0JFT6_SPIOL
neXtProt»
0.0
LOC110805746 TsaA-like domain-containing protein Spinacia oleracea
TI:3562 None
   
A0A9R1WYP6_LACSA
euHCVdb»
0.0
LSAT_V11C800415560 TsaA-like domain-containing protein Lactuca sativa
TI:4236 None
 
A2EBW9_TRIV3
TubercuList»
0.0
TVAG_259180 TsaA-like domain-containing protein Trichomonas vaginalis
TI:5722 None
 
A2FC71_TRIV3
TubercuList»
0.0
TVAG_335440 TsaA-like domain-containing protein Trichomonas vaginalis
TI:5722 None
 
A2FP34_TRIV3
TubercuList»
0.0
TVAG_181300 TsaA-like domain-containing protein Trichomonas vaginalis
TI:5722 None
 
A8B9W2_GIAIC
TubercuList»
0.0
GL50803_003079 Uncharacterized protein Giardia intestinalis
TI:5741 None
 
A8BLG2_GIAIC
TubercuList»
0.0
GL50803_008191 Uncharacterized protein Giardia intestinalis
TI:5741 None
 
B3S8C2_TRIAD
CTD»
0.0
TRIADDRAFT_60485 TsaA-like domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B7QIF9_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW014570 TsaA-like domain-containing protein Ixodes scapularis
TI:6945 None
 
B8CFY9_THAPS
euHCVdb»
0.0
THAPSDRAFT_25788 TsaA-like domain-containing protein Thalassiosira pseudonana
TI:35128 None
 
B9IM43_POPTR
euHCVdb»
0.0
POPTR_018G096900 TsaA-like domain-containing protein Populus trichocarpa
TI:3694 None
 
B9T0H6_RICCO
euHCVdb»
0.0
RCOM_0729440 Protein virR, putative Ricinus communis
TI:3988 None
 
C4M5R2_ENTH1
TubercuList»
0.0
EHI_129960 TsaA-like domain-containing protein Entamoeba histolytica
TI:5759 None
 
D6WQW9_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_30545 Nef-associated protein 1-like Protein Tribolium castaneum
TI:7070 None
 
D7SQ29_VITVI
euHCVdb»
0.0
VIT_11s0052g01830 TsaA-like domain-containing protein Vitis vinifera
TI:29760 None
 
D8QXW5_SELML
euHCVdb»
0.0
SELMODRAFT_270356 TsaA-like domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8RUM5_SELML
neXtProt»
0.0
SELMODRAFT_271086 TsaA-like domain-containing protein Selaginella moellendorffii
TI:88036 None
 
F0ZKF0_DICPU
TubercuList»
0.0
DICPUDRAFT_78739 TsaA-like domain-containing protein Dictyostelium purpureum
TI:5786 None
 
F0ZXQ8_DICPU
TubercuList»
0.0
DICPUDRAFT_82827 TsaA-like domain-containing protein Dictyostelium purpureum
TI:5786 None
 
F6SJZ1_ORNAN
Ensembl»
0.0
TRMO TsaA-like domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
H3GL53_PHYRM
EnsemblProtists»
0.0
TsaA-like domain-containing protein Phytophthora ramorum
TI:164328 None
 
I1LVU9_SOYBN
EnsemblPlants»
0.0
GLYMA_13G093000 TsaA-like domain-containing protein Glycine max
TI:3847 None
 
I1MSV1_SOYBN
EnsemblPlants»
0.0
LOC100808885 TsaA-like domain-containing protein Glycine max
TI:3847 None
 
K3ZU37_SETIT
EnsemblPlants»
0.0
LOC101773584 TsaA-like domain-containing protein Setaria italica
TI:4555 None
 
M1CM18_SOLTU
EnsemblPlants»
0.0
LOC102584684 Protein virR Solanum tuberosum
TI:4113 None
   
M4D1N6_BRACM
EnsemblPlants»
0.0
TsaA-like domain-containing protein Brassica campestris
TI:3711 None
   
Q4QBT8_LEIMA
TubercuList»
0.0
LMJF_22_0590 TsaA-like domain-containing protein Leishmania major
TI:5664 None
 
Q54CD3_DICDI
dictyBase»
0.5
DDB_G0293042 TsaA-like domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q54N07_DICDI
dictyBase»
0.5
DDB_G0285577 TsaA-like domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q5JED3_THEKO
EnsemblBacteria»
0.0
TK0027 TsaA-like domain-containing protein Thermococcus kodakarensis
TI:311400 None
 
Q5JG53_THEKO
EnsemblBacteria»
0.0
TK0711 TsaA-like domain-containing protein Thermococcus kodakarensis
TI:311400 None
 
Q69L12_ORYSJ
euHCVdb»
0.0
Os09g0428900 Os09g0428900 protein (cDNA
clone:J023143B18, full insert sequence)		 Oryza sativa
TI:4530 None
 
Q74B22_GEOSL
EnsemblBacteria»
0.0
GSU2411 TsaA-like domain-containing protein Geobacter sulfurreducens
TI:35554 None
 
Q89JY3_BRADU
EnsemblBacteria»
0.0
virR VirR Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q9JX96_NEIMB
neXtProt»
0.0
NMB2158 TsaA-like domain-containing protein Neisseria meningitidis
TI:487 None
 
Q9WY31_THEMA
EnsemblBacteria»
0.0
TM_0188 TsaA-like domain-containing protein Thermotoga maritima
TI:2336 None
 
W1PHX4_AMBTC
neXtProt»
0.0
AMTR_s00019p00173490 TsaA-like domain-containing protein Amborella trichopoda
TI:13333 None
 
A0A1S4H9A9_ANOGA
EnsemblMetazoa»
0.0
TsaA-like domain-containing protein Anopheles gambiae
TI:7165 None 		 
 
A0ABI7WSK4_FELCA
Ensembl»
0.0
TRMO TsaA-like domain-containing protein Felis catus
TI:9685 None 		     
A5I2D9_CLOBH
euHCVdb»
0.0
CBO1671 TsaA-like domain-containing protein Clostridium botulinum
TI:1491 None 		 
 
A9V8A2_MONBE
euHCVdb»
0.0
MONBRDRAFT_11127 TsaA-like domain-containing protein Monosiga brevicollis
TI:81824 None 		 
 
B1L3U1_KORCO
EnsemblBacteria»
0.0
Kcr_0364 TsaA-like domain-containing protein Korarchaeum cryptofilum
TI:498846 None 		 
 
B5YKZ5_THEYD
EnsemblBacteria»
0.0
THEYE_A1086 TsaA-like domain-containing protein Thermodesulfovibrio yellowstonii
TI:28262 None 		 
 
B8BYR5_THAPS
neXtProt»
0.0
THAPSDRAFT_32920 TsaA-like domain-containing protein Thalassiosira pseudonana
TI:35128 None 		 
 
D7TXT0_VITVI
neXtProt»
0.0
VIT_17s0053g00800 TsaA-like domain-containing protein Vitis vinifera
TI:29760 None 		 
 
F6U8L4_CIOIN
Ensembl»
0.0
TsaA-like domain-containing protein Ciona intestinalis
TI:7719 None 		 
 
Q81E18_BACCR
euHCVdb»
0.0
BC_2178 Transcriptional regulator Bacillus cereus
TI:1396 None 		 
 
Q8TTP4_METAC
EnsemblBacteria»
0.0
MA_0382 TsaA-like domain-containing protein Methanosarcina acetivorans
TI:2214 None 		 
 
Q8ZTZ9_PYRAE
EnsemblBacteria»
0.0
PAE3010 TsaA-like domain-containing protein Pyrobaculum aerophilum
TI:13773 None 		 
 
Q8ZV50_PYRAE
EnsemblBacteria»
0.0
PAE2456 TsaA-like domain-containing protein Pyrobaculum aerophilum
TI:13773 None 		 
 
Q97U53_SACS2
EnsemblBacteria»
0.0
SSO3170 TsaA-like domain-containing protein Saccharolobus solfataricus
TI:2287 None 		 
 
Q9KYJ3_STRCO
euHCVdb»
0.0
SCO6948 TsaA-like domain-containing protein Streptomyces coelicolor
TI:1902 None 		 
 
T1G380_HELRO
EnsemblMetazoa»
0.0
20215528 TsaA-like domain-containing protein Helobdella robusta
TI:6412 None 		 
 
Y1115_HALSA
euHCVdb»
0.0
VNG_1115H Probable S-adenosyl-L-methionine-binding
protein VNG_1115H		 Halobacterium salinarum
TI:2242 None 		 
 
Y1583_METJA
EnsemblBacteria»
0.0
MJ1583 Probable S-adenosyl-L-methionine-binding
protein MJ1583		 Methanocaldococcus jannaschii
TI:2190 None