Collated Gene Ontology terms

Biological process: hydrolase activity(2025) 5-oxoprolinase (ATP-hydrolyzing) activity(2009, 2013, 2023, 2024, 2025) catalytic activity(2025) identical protein binding(2025) ATP binding(2025) nucleotide binding(2025) N-methylhydantoinase (ATP-hydrolyzing) activity(2025) zinc ion binding(2025) ATP hydrolysis activity(2025)

Molecular function: glutathione metabolic process2009, 2010, 2013, 2017, 2025 cellular detoxification2015 glutathione catabolic process2009

Cellular component: cytosol2009, 2014, 2019, 2023, 2025 cytoplasm2009, 2018, 2025 plastid2019 plasmodesma2021 plasma membrane2010

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 4/8 
Bacteria: 10/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8V0XX21_CHICK
Ensembl»
0.0
Hydantoinase B/oxoprolinase
domain-containing protein		 Gallus gallus
TI:9031 None
   
A0A9S2_CAEEL
WormBase»
1.0
CELE_Y38F2AR.12 Y38F2AR.12 5-oxoprolinase Caenorhabditis elegans
TI:6239 None
 
E7F6Z6_DANRE
ZFIN»
1.0
oplah 5-oxoprolinase (EC
3.5.2.9) (5-oxoprolinase, ATP-hydrolysing)		 Danio rerio
TI:7955 None
 
OPLA_ARATH
TAIR»
2.6
OXP1 5-oxoprolinase 1 (EC 3.5.2.9) (5-oxo-L-prolinase)
(5-OPase) (Protein OXOPROLINASE 1) (Pyroglutamase)		 Arabidopsis thaliana
TI:3702 None
 
OPLA_DICDI
dictyBase»
1.5
oplah 5-oxoprolinase (EC 3.5.2.9)
(5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)		 Dictyostelium discoideum
TI:44689 None
 
OPLA_HUMAN
Ensembl»
3.2
OPLAH 5-oxoprolinase (EC 3.5.2.9)
(5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)		 Homo sapiens
TI:9606 None
 
OPLA_MOUSE
Ensembl»
2.5
Oplah 5-oxoprolinase (EC 3.5.2.9)
(5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)		 Mus musculus
TI:10090 None
 
OPLA_RAT
RGD»
2.0
Oplah 5-oxoprolinase (EC 3.5.2.9)
(5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)		 Rattus norvegicus
TI:10116 None
 
OPLA_YEAST
SGD»
4.2
OXP1 5-oxoprolinase (EC 3.5.2.9)
(5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)		 Saccharomyces cerevisiae
TI:4932 None
 
Q9W247_DROME
FlyBase»
1.0
Dmel\CG4752 FI03324p (RH09675p) Drosophila melanogaster
TI:7227 None
 
YAOE_SCHPO
PomBase»
1.6
SPAC11D3.14c Uncharacterized protein C11D3.14c Schizosaccharomyces pombe
TI:4896 None
 
YAOF_SCHPO
PomBase»
1.6
SPAC11D3.15 Uncharacterized protein C11D3.15 Schizosaccharomyces pombe
TI:4896 None