Collated Gene Ontology terms

Biological process: G protein-coupled receptor binding(2012, 2025) heparin binding(2025) chemoattractant activity(2014) Toll-like receptor 4 binding(2014)

Molecular function: acute-phase response2025 positive regulation of synoviocyte proliferation2021, 2022, 2025 response to bacterium2007, 2018 positive regulation of cytosolic calcium ion concentration2012, 2025 positive regulation of cell adhesion2012, 2025 response to stilbenoid2011 positive regulation of cytokine production2012, 2025 macrophage chemotaxis2012, 2025 lymphocyte chemotaxis2012, 2025 regulation of protein secretion2012
positive regulation of lipid catabolic process2015 positive regulation of interleukin-1 production2012 positive regulation of ERK1 and ERK2 cascade2015 positive chemotaxis2025 platelet activation2012 neutrophil migration2015 neutrophil chemotaxis2012 negative regulation of inflammatory response2012 negative regulation of gene expression2015 lipid catabolic process2015 cholesterol metabolic process2007 cellular response to interleukin-12014 cell maturation2020 cell chemotaxis2014 I-kappaB phosphorylation2014

Cellular component: nucleus2018, 2020, 2021, 2025 extracellular region2004, 2012, 2013, 2025 high-density lipoprotein particle2025 nucleoplasm2022, 2024, 2025 cytoplasmic microtubule2013, 2025 extracellular exosome2014 extracellular space2007, 2014 endocytic vesicle lumen2013

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SAA2_HUMAN
Ensembl»
0.0
SAA2 Serum amyloid A-2 protein (SAA2)
[Cleaved into: Amyloid A2 protein (AA2)]		 Homo sapiens
TI:9606 None
 
SAA1_HUMAN
Ensembl»
9.0
SAA1 Serum amyloid A-1 protein (SAA) [Cleaved into: Amyloid protein A (Amyloid fibril protein AA); Serum amyloid protein
A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(2-103); Serum amyloid protein A(2-102); Serum amyloid protein A(4-101)]		 Homo sapiens
TI:9606 None
 
SAA4_HUMAN
Ensembl»
0.0
SAA4 Serum amyloid A-4 protein (Constitutively
expressed serum amyloid A protein) (C-SAA)		 Homo sapiens
TI:9606 None
 
SAA3_MOUSE
Ensembl»
6.1
Saa3 Serum amyloid A-3 protein Mus musculus
TI:10090 None
 
SAAL1_MOUSE
Ensembl»
1.0
Saal1 Protein SAAL1 (Synoviocyte proliferation-associated in
collagen-induced arthritis protein 1) (SPACIA1)		 Mus musculus
TI:10090 None
 
Q642J9_DANRE
ZFIN»
2.4
saa Serum amyloid A protein Danio rerio
TI:7955 None
 
SAA4_MOUSE
Ensembl»
0.0
Saa4 Serum amyloid A-4 protein (Amyloid A-5 protein) Mus musculus
TI:10090 None
 
C0Z225_ARATH
TAIR»
0.0
MRN17.5 ARM repeat superfamily
protein (AT5G22820 protein)		 Arabidopsis thaliana
TI:3702 None
 
SAA2_MOUSE
Ensembl»
1.3
Saa2 Serum amyloid A-2 protein
[Cleaved into: Amyloid protein A]		 Mus musculus
TI:10090 None
 
SAAL1_HUMAN
Ensembl»
1.3
SAAL1 Protein SAAL1 (Synoviocyte proliferation-associated in
collagen-induced arthritis protein 1) (SPACIA1)		 Homo sapiens
TI:9606 None
 
Q7K4H1_DROME
FlyBase»
0.0
CG8185 LD40680p Drosophila melanogaster
TI:7227 None
 
SAA1_MOUSE
Ensembl»
2.1
Saa1 Serum amyloid A-1 protein Mus musculus
TI:10090 None
 
A0A096LPE2_HUMAN
Ensembl»
0.0
SAA2-SAA4 SAA2-SAA4 readthrough Homo sapiens
TI:9606 None
 
Q7TP01_RAT
RGD»
1.0
Saal1 Bq135360 (Serum amyloid A-like 1) Rattus norvegicus
TI:10116 None
 
SAAL1_DANRE
ZFIN»
0.5
saal1 Protein saal1 Danio rerio
TI:7955 None
 
A0A8V0ZXK9_CHICK
Ensembl»
0.0
SAA Serum amyloid A protein Gallus gallus
TI:9031 None
   
A0A8V1A1K4_CHICK
Ensembl»
0.5
SAAL1 Serum amyloid A like 1 Gallus gallus
TI:9031 None