Collated Gene Ontology terms

Biological process: metal ion binding(2008, 2025) cytochrome-c oxidase activity(2003, 2005, 2013, 2023, 2025) zinc ion binding(2013, 2021, 2022, 2025) oxidoreductase activity(2025) cobalt ion binding(2021)

Molecular function: mitochondrial electron transport, cytochrome c to oxygen2021, 2024, 2025 proton transmembrane transport2025 oxidative phosphorylation2024 mitochondrial respiratory chain complex IV assembly2012, 2025 maintenance of translational fidelity2025 cellular respiration2025 proton motive force-driven mitochondrial ATP synthesis2012, 2025 lipid storage2006, 2025 determination of adult lifespan2012, 2025 response to thyroid hormone2008
response to peptide hormone2008 response to bacterium2009 respiratory gaseous exchange by respiratory system2003

Cellular component: mitochondrion2005, 2006, 2009, 2014, 2018, 2021, 2024, 2025 respiratory chain complex IV2013, 2019, 2021, 2023, 2024, 2025 mitochondrial envelope2025 mitochondrial inner membrane2005, 2011, 2013, 2024, 2025 mitochondrial membrane2025 plasma membrane2014 phagocytic vesicle2009 myelin sheath2014 mitochondrial intermembrane space2011 cytosol2019
chloroplast thylakoid membrane2021 acrosomal vesicle2025

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
COX4_YEAST
SGD»
5.9
COX4 Cytochrome c oxidase subunit 4,
mitochondrial (Cytochrome c oxidase polypeptide IV)		 Saccharomyces cerevisiae
TI:4932 None
 
COX5B_HUMAN
Ensembl»
3.5
COX5B Cytochrome c oxidase subunit 5B,
mitochondrial (Cytochrome c oxidase polypeptide Vb)		 Homo sapiens
TI:9606 None
 
CX5B1_ARATH
TAIR»
2.3
COX5B-1 Cytochrome c oxidase
subunit 5b-1, mitochondrial (AtCOX5b-1)		 Arabidopsis thaliana
TI:3702 None
 
CX5B2_ARATH
TAIR»
0.5
COX5B-2 Cytochrome c oxidase
subunit 5b-2, mitochondrial (AtCOX5b-2)		 Arabidopsis thaliana
TI:3702 None
 
CX5BL_ARATH
TAIR»
0.5
At1g52710 Putative cytochrome c oxidase subunit 5b-like Arabidopsis thaliana
TI:3702 None
 
COX5B_RAT
RGD»
3.0
Cox5b Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c
oxidase polypeptide Vb) (Cytochrome c oxidase subunit VIA*)		 Rattus norvegicus
TI:10116 None
 
COX5_DICDI
dictyBase»
1.0
cxeA Cytochrome c oxidase subunit 5
(Cytochrome c oxidase polypeptide V)		 Dictyostelium discoideum
TI:44689 None
 
Q0P3U4_DANRE
ZFIN»
0.5
cox5b2 Cytochrome c oxidase subunit 5B,
mitochondrial (Cytochrome c oxidase polypeptide Vb)		 Danio rerio
TI:7955 None
 
Q9VMB8_DROME
FlyBase»
1.1
COX5BL Cytochrome c oxidase
subunit 5B-like (GEO10787p1) (IP07710p)		 Drosophila melanogaster
TI:7227 None
 
Q9VMB9_DROME
FlyBase»
2.6
COX5B Cytochrome c oxidase subunit 5B, isoform A
(Cytochrome c oxidase subunit 5B, isoform B) (RE06394p)		 Drosophila melanogaster
TI:7227 None
 
COX4_SCHPO
PomBase»
2.5
cox4 Cytochrome c oxidase subunit 4,
mitochondrial (Cytochrome c oxidase polypeptide IV)		 Schizosaccharomyces pombe
TI:4896 None
 
COX5B_MOUSE
AG»
0.5
Cox5b Cytochrome c oxidase subunit 5B,
mitochondrial (Cytochrome c oxidase polypeptide Vb)		 Mus musculus
TI:10090 None
 
P90849_CAEEL
WormBase»
2.9
cox-5b COX5B-domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q6IQU9_DANRE
ZFIN»
0.5
cox5ba Cytochrome c oxidase subunit 5B,
mitochondrial (Cytochrome c oxidase polypeptide Vb)		 Danio rerio
TI:7955 None
 
A0A8V0Z2Y8_CHICK
Ensembl»
0.5
COX5B Cytochrome c oxidase subunit 5B,
mitochondrial (Cytochrome c oxidase polypeptide Vb)		 Gallus gallus
TI:9031 None
   
A0AB13A3X0_DANRE
ZFIN»
0.0
cox5bb Cytochrome c oxidase subunit 5B,
mitochondrial (Cytochrome c oxidase polypeptide Vb)		 Danio rerio
TI:7955 None