Collated Gene Ontology terms

Biological process: transcription coregulator activity(2007, 2024) transcription coactivator activity(2016, 2023)

Molecular function: regulation of transcription by RNA polymerase II2007, 2022, 2024 positive regulation of transcription initiation by RNA polymerase II2014, 2018, 2023 positive regulation of transcription elongation by RNA polymerase II2014, 2018 RNA polymerase II preinitiation complex assembly2014, 2018 transcription initiation at RNA polymerase II promoter2023 positive regulation of transcription by RNA polymerase II2015 mitotic cell cycle2010

Cellular component: mediator complex2005, 2007, 2012, 2020, 2023, 2024 nucleus2009, 2011, 2014, 2018, 2024 core mediator complex2014, 2015, 2018, 2024 nucleoplasm2010, 2013 nucleolus2016 cytoplasm2003 chromatin2016

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 7/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
MD22A_ARATH
TAIR»
0.0
MED22A Mediator of RNA polymerase
II transcription subunit 22a		 Arabidopsis thaliana
TI:3702 None
 
MD22B_ARATH
TAIR»
0.0
MED22B Mediator of RNA polymerase
II transcription subunit 22b		 Arabidopsis thaliana
TI:3702 None
 
MED22_CAEEL
WormBase»
0.0
mdt-22 Mediator of RNA polymerase II transcription
subunit 22 (Mediator complex subunit 22)		 Caenorhabditis elegans
TI:6239 None
 
MED22_DANRE
ZFIN»
0.0
med22 Mediator of RNA polymerase II transcription subunit 22
(Mediator complex subunit 22) (Surfeit locus protein 5)		 Danio rerio
TI:7955 None
 
MED22_DICDI
dictyBase»
0.5
med22 Putative mediator of RNA polymerase II transcription
subunit 22 (Putative mediator complex subunit 22)		 Dictyostelium discoideum
TI:44689 None
 
MED22_DROME
FlyBase»
3.3
MED22 Mediator of RNA polymerase II transcription
subunit 22 (Mediator complex subunit 22) (dMED24)		 Drosophila melanogaster
TI:7227 None
 
Q86BK9_DROME
FlyBase»
0.0
Dmel\CG32971 Mediator of RNA polymerase II transcription
subunit 22 (Mediator complex subunit 22)		 Drosophila melanogaster
TI:7227 None
 
A0A8V1AFQ2_CHICK
Ensembl»
0.0
MED22 Mediator of RNA polymerase II transcription subunit 22
(Mediator complex subunit 22) (Surfeit locus protein 5)		 Gallus gallus
TI:9031 None
   
MED22_CHICK
CTD»
0.0
MED22 Mediator of RNA polymerase II transcription subunit 22
(Mediator complex subunit 22) (Surfeit locus protein 5)		 Gallus gallus
TI:9031 None
 
MED22_HUMAN
Ensembl»
1.8
MED22 Mediator of RNA polymerase II transcription subunit 22
(Mediator complex subunit 22) (Surfeit locus protein 5) (Surf-5)		 Homo sapiens
TI:9606 None
 
MED22_MOUSE
Ensembl»
1.8
Med22 Mediator of RNA polymerase II transcription subunit 22
(Mediator complex subunit 22) (Surfeit locus protein 5) (Surf-5)		 Mus musculus
TI:10090 None
 
MED22_RAT
RGD»
0.0
Med22 Mediator of RNA polymerase II transcription subunit 22
(Mediator complex subunit 22) (Surfeit locus protein 5)		 Rattus norvegicus
TI:10116 None
 
MED22_SCHPO
PomBase»
3.2
med22 Mediator of RNA polymerase II transcription subunit 22 (Mediator
complex subunit 22) (Suppressor of RNA polymerase B 6 homolog)		 Schizosaccharomyces pombe
TI:4896 None