Collated Gene Ontology terms

Biological process: oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(2020, 2025) oxidoreductase activity(2021, 2025) oxidoreductase activity, acting on a sulfur group of donors(2011, 2020, 2021, 2025) ribonuclease T2 activity(2025) RNA binding(2025) protein-disulfide reductase [NAD(P)H] activity(2012) disulfide oxidoreductase activity(2002)

Molecular function: immune system process2025 antigen processing and presentation of exogenous peptide antigen via MHC class I2011, 2025 antigen processing and presentation of exogenous peptide antigen via MHC class II2002, 2025 protein stabilization2008 positive regulation of defense response to bacterium2014 negative regulation of fibroblast proliferation2008 hematopoietic stem cell proliferation2024 cell redox homeostasis2024

Cellular component: extracellular region2003, 2018, 2025 lysosome2003, 2011, 2020, 2025 plasma membrane2018 membrane2025 secretory vesicle2019 plant-type vacuole2021 lysosomal lumen2013 cytosol2025 cytoplasm2012 cell junction2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 7/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q93VQ6_ARATH
TAIR»
0.5
At1g07080 At1g07080/F10K1_15 (Interferon inducible-lysosomal thiol
reductase) (Thioredoxin superfamily protein)		 Arabidopsis thaliana
TI:3702 None
 
Q0V809_ARATH
TAIR»
0.5
At4g12890 At4g12890 (Gamma interferon responsive lysosomal
thiol (GILT) reductase family protein)		 Arabidopsis thaliana
TI:3702 None
 
Q9VHA5_DROME
FlyBase»
0.5
Dmel\CG9427 GH19763p (Uncharacterized protein, isoform
A (EC 1.-.-.-, EC 1.8.4.-))		 Drosophila melanogaster
TI:7227 None
 
GILT1_DROME
FlyBase»
1.8
GILT1 GILT-like protein 1 Drosophila melanogaster
TI:7227 None
 
GILT2_DROME
FlyBase»
1.8
GILT2 GILT-like protein 2 (EC 1.8.-.-) Drosophila melanogaster
TI:7227 None
 
GILT3_DROME
FlyBase»
1.0
GILT3 GILT-like protein 3 Drosophila melanogaster
TI:7227 None
 
YKJ2_CAEEL
WormBase»
0.5
C02D5.2 GILT-like protein C02D5.2 Caenorhabditis elegans
TI:6239 None
 
YVRI_CAEEL
WormBase»
0.5
F37H8.5 GILT-like protein F37H8.5 Caenorhabditis elegans
TI:6239 None
 
YO30_CAEEL
WormBase»
0.5
ZK669.3 GILT-like protein ZK669.3 Caenorhabditis elegans
TI:6239 None
 
Q21830_CAEEL
WormBase»
0.5
CELE_R07E5.4 R07E5.4 Gamma interferon inducible
lysosomal thiol reductase		 Caenorhabditis elegans
TI:6239 None
 
Q8VY56_ARATH
TAIR»
0.5
At4g12870 Gamma interferon responsive lysosomal
thiol (GILT) reductase family protein		 Arabidopsis thaliana
TI:3702 None
 
Q9M017_ARATH
TAIR»
0.5
OSH1 Gamma interferon responsive lysosomal
thiol (GILT) reductase family protein		 Arabidopsis thaliana
TI:3702 None
 
Q9SV79_ARATH
TAIR»
0.5
At4g12900 Gamma interferon responsive lysosomal
thiol (GILT) reductase family protein		 Arabidopsis thaliana
TI:3702 None
 
A0ACD6B723_DANRE
ZFIN»
0.0
ifi30b Gamma-interferon-inducible lysosomal
thiol reductase		 Danio rerio
TI:7955 None 		     
Q23569_CAEEL
WormBase»
0.5
CELE_ZK669.2 ZK669.2 Gamma-interferon-inducible lysosomal
thiol reductase		 Caenorhabditis elegans
TI:6239 None
 
Q9XW24_CAEEL
WormBase»
0.5
CELE_Y18D10A.2 Y18D10A.2 Gamma-interferon-inducible lysosomal
thiol reductase		 Caenorhabditis elegans
TI:6239 None
 
A0A8V1AG08_CHICK
Ensembl»
0.5
IFI30 Gamma-interferon-inducible lysosomal thiol reductase
(EC 1.8.-.-) (Gamma-interferon-inducible protein IP-30)		 Gallus gallus
TI:9031 None
   
GILT_HUMAN
Ensembl»
3.5
IFI30 Gamma-interferon-inducible lysosomal thiol reductase (EC
1.8.4.-) (Gamma-interferon-inducible protein IP-30) (Legumaturain)		 Homo sapiens
TI:9606 None
 
GILT_RAT
RGD»
4.5
Ifi30 Gamma-interferon-inducible lysosomal thiol reductase (EC
1.8.4.-) (Interferon gamma inducible protein 30)		 Rattus norvegicus
TI:10116 None
 
GILT_MOUSE
Ensembl»
6.1
Ifi30 Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.4.-)
(Gamma-interferon-inducible protein IP-30) (Lysosomal thiol reductase IP30)		 Mus musculus
TI:10090 None
 
GILT_DANRE
ZFIN»
3.7
ifi30a Gamma-interferon-inducible lysosomal thiol reductase (zGILT)
(EC 1.8.4.-) (Gamma-interferon-inducible protein IP-30)		 Danio rerio
TI:7955 None
 
GILT_ARATH
TAIR»
0.5
GILT Gamma-interferon-responsive lysosomal
thiol protein (AtGILT)		 Arabidopsis thaliana
TI:3702 None
 
O76576_CAEEL
WormBase»
0.5
pqn-48 Prion-like-(Q/N-rich)-domain-bearing protein Caenorhabditis elegans
TI:6239 None
 
A0A0C4DHN2_DROME
FlyBase»
0.5
Dmel\CG41378 Uncharacterized protein, isoform B
(EC 1.-.-.-, EC 1.8.4.-)		 Drosophila melanogaster
TI:7227 None