Collated Gene Ontology terms

Biological process: peptidyl-tRNA hydrolase activity(2013, 2017, 2025) hydrolase activity(2025)

Molecular function: positive regulation of anoikis2014, 2019, 2025 negative regulation of anoikis2012, 2019, 2025 negative regulation of gene expression2012, 2025 translation2025 negative regulation of proteasomal ubiquitin-dependent protein catabolic process2013, 2025 rescue of stalled ribosome2025 apoptotic process2025

Cellular component: cytosol2014, 2017, 2025 mitochondrion2009, 2012, 2014, 2018, 2024, 2025 mitochondrial outer membrane2018, 2023, 2024, 2025 cytoplasm2025 mitochondrial membrane2025 mitochondrial inner membrane2025 plasma membrane2019 nucleus2017 membrane2014 endoplasmic reticulum2025
cytoplasmic side of mitochondrial outer membrane2025 chloroplast2018

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 8/8 
Bacteria: 1/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8I5ZZ93_RAT
RGD»
2.0
Ptrh2 peptidyl-tRNA hydrolase (EC 3.1.1.29) Rattus norvegicus
TI:10116 None
   
E1BWS4_CHICK
Ensembl»
1.5
PTRH2 Peptidyl-tRNA hydrolase 2,
mitochondrial (EC 3.1.1.29)		 Gallus gallus
TI:9031 None
   
F4JV77_ARATH
TAIR»
0.5
At4g32900 peptidyl-tRNA hydrolase (EC 3.1.1.29) Arabidopsis thaliana
TI:3702 None
 
I3ITK3_DANRE
ZFIN»
0.5
si:dkey-19e4.5 peptidyl-tRNA hydrolase (EC 3.1.1.29) Danio rerio
TI:7955 None
 
PTH2_CAEEL
WormBase»
0.5
C24G6.8 Probable peptidyl-tRNA hydrolase 2
(PTH 2) (EC 3.1.1.29)		 Caenorhabditis elegans
TI:6239 None
 
PTH2_DICDI
dictyBase»
0.5
pth2 Probable peptidyl-tRNA hydrolase 2
(PTH 2) (EC 3.1.1.29)		 Dictyostelium discoideum
TI:44689 None
 
PTH2_DROME
FlyBase»
0.5
CG1307 Probable peptidyl-tRNA hydrolase 2
(PTH 2) (EC 3.1.1.29)		 Drosophila melanogaster
TI:7227 None
 
PTH2_HUMAN
Ensembl»
4.7
PTRH2 Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2)
(EC 3.1.1.29) (Bcl-2 inhibitor of transcription 1)		 Homo sapiens
TI:9606 None
 
PTH2_MOUSE
Ensembl»
3.5
Ptrh2 Peptidyl-tRNA hydrolase 2, mitochondrial
(PTH 2) (EC 3.1.1.29)		 Mus musculus
TI:10090 None
 
PTH2_SCHPO
PomBase»
1.0
SPAC19A8.14 Probable peptidyl-tRNA hydrolase 2
(PTH 2) (EC 3.1.1.29)		 Schizosaccharomyces pombe
TI:4896 None
 
PTH2_YEAST
SGD»
3.7
PTH2 Peptidyl-tRNA hydrolase 2 (PTH 2) (EC 3.1.1.29) Saccharomyces cerevisiae
TI:4932 None
 
Q1H5E3_ARATH
TAIR»
0.5
At5g16870 peptidyl-tRNA hydrolase (EC 3.1.1.29) Arabidopsis thaliana
TI:3702 None
 
Q9M8U2_ARATH
TAIR»
0.5
At3g03010 peptidyl-tRNA hydrolase (EC 3.1.1.29) Arabidopsis thaliana
TI:3702 None
 
Q9VG06_DROME
FlyBase»
0.5
Dmel\CG17327 peptidyl-tRNA hydrolase (EC 3.1.1.29) Drosophila melanogaster
TI:7227 None